Endothelial progenitor cells are recruited into resolving venous thrombi

Circulation

Volumn 111, Issue 20, 2005, Pages 2645-2653

  Modarai, B ^a   Burnand, K G ^a   Sawyer, B ^a   Smith, A ^a,b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

Angiogenesis; Cells; Revascularization; Thrombus

Indexed keywords

ANGIOPOIETIN RECEPTOR; CD68 ANTIGEN; CELL MARKER; GREEN FLUORESCENT PROTEIN; VASCULOTROPIN RECEPTOR 2;

ARTICLE; BONE MARROW; CONTROLLED STUDY; DONOR; ENDOTHELIUM CELL; FLOW CYTOMETRY; HISTOLOGY; MACROPHAGE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; STEM CELL; TISSUE SECTION; VEIN THROMBOSIS; WILD TYPE;

ANIMALS; ANTIGENS, CD34; ANTIGENS, SURFACE; BONE MARROW TRANSPLANTATION; CELL MOVEMENT; ENDOTHELIUM, VASCULAR; GREEN FLUORESCENT PROTEINS; MACROPHAGES, PERITONEAL; MICE; RECEPTOR, TIE-2; STEM CELLS; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2; VENOUS THROMBOSIS;

EID: 19644385523     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.104.492678     Document Type: Article

References (37)

1. Wakefield TW, Linn MJ, Henke PK, Kadell AM, Wilke CA, Wrobleski SK, Sarkar M, Burdick MD, Myers DD, Stricter RM. Neovascularization during venous thrombosis organization: a preliminary study. J Vasc Surg. 1999;30:885-892.
2. Kwaan HCGG. Clinical use of 51 Cr-leukocytes in the detection of DVT. Circulation. 1971;44;55-59.
3. McGuinness CL, Humphries J, Waltham M, Burnand KG, Collins M, Smith A. Recruitment of labelled monocytes by experimental venous thrombi. Thromb Haemost. 2001;85;1018-1024.
4. Sevitt S. The mechanisms of canalisation in deep vein thrombosis. J Pathol. 1973:110:153-165.
5. Meissner MH, Zierler BK, Bergelin RO, Chandler WL, Strandness DE Jr. Coagulation, fibrinolysis, and recanalization after acute deep venous thrombosis. J Vase Surg. 2002:35:278-285.
6. Waltham M, Burnand KG. Collins M, Smith A. Vascular endothelial growth factor and basic fibroblast growth factor are found in resolving venous thrombi. J Vase Surg. 2000:32:988-996.
7. Asahara T, Takahashi T, Masuda H, Kalka C, Chen D, Iwaguro H, Inai Y, Silver M, Isner JM. VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells. EMBO J. 1999;18:3964-3972.
8. Isner JM, Kalka C, Kawamoto A, Asahara T, Bone marrow as a source of endothelial cells for natural and iatrogenic vascular repair. Ann N Y Acad Sci. 2001;953:75-84.
9. Rafii S, Lyden D. Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration. Nat Med. 2003;9:702-712.
10. Singh I, Burnand KG, Collins M, Luttun A, Collen D, Boelhouwer B, Smith A. Failure of thrombus to resolve in urokinase-type plasminogen activator gene-knockout mice: rescue by normal bone marrow-derived cells. Circulation. 2003:107:869-875.
11. Sato TN, Tozawa Y, Deutsch U, Wolburg-Buchholz K, Fujiwara Y, Gendron-Maguire M, Gridley T, Wolburg H, Risau W, Qin Y. Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature, 1995:376:70-74.
12. Motoike T, Loughna S, Perens E, Roman BL, Liao W, Chau TC, Richardson CD, Kawate T, Kuno J, Weinstein BM, Stainier DY, Sato TN, Universal GFP reporter for the study of vascular development. Genesis, 2000:28:75-81.
13. Leijh PC, van Zwet TL, ter Kuile MN, van Furth R. Effect of thioglycolate on phagocytic and microbicidal activities of peritoneal macrophages. Infect Immun. 1984:46:448-452.
14. Li YM, Baviello G, Vlassara H, Mitsuhashi T. Glycation products in aged thioglycollate medium enhance the elicitation of peritoneal macrophages. J Immunol Methods. 1997;201:183-188.
15. Ho MK, Springer TA. Tissue distribution, structural characterization, and biosynthesis of Mac-3, a macrophage surface glycoprotein exhibiting molecular weight heterogeneity. J Biol Chem. 1983;258:636-642.
16. Hume DA, Ross IL, Himes SR, Sasmono RT, Wells CA, Ravasi T. The mononuclear phagocyte system revisited. J Leukoc Biol. 2002;72: 621-627.
17. Thomas ML, The leukocyte common antigen family. Anna Rev Immunol. 1989;7:339-369.
18. Ismail JA, Poppa V, Kemper LE, Scatena M, Giachelli CM, Coffin JD, Murry CE, Immunohistologic labeling of murine endothelium. Cardiovasc Pathol. 2003;12:82-90.
19. Tamaki T, Akatsuka A, Ando K, Nakamura Y, Matsuzawa H, Hotta T, Roy RR, Edgerton VR. Identification of myogenic-endothelial progenitor cells in the interstitial spaces of skeletal muscle. J Cell Biol. 2002:157: 571-577.
20. Breier G, Clauss M, Risau W. Coordinate expression of vascular endothelial growth factor receptor-1 (flt-1) and its ligand suggests a paracrine regulation of murine vascular development, Dev Dyn. 1995;204: 228-239.
21. Ziegelhoeffer T, Fernandez B, Kostin S, Heil M, Voswinckel R, Helisch A, Schaper W, Bone marrow-derived cells do not incorporate into the adult growing vasculature. Circ Res. 2004:94:230-238.
22. Tepper O, Murayama T, Kearney M. Therapeutic neovascularization as a novel approach to thrombus recanalization and resolution. Circulation. 2002;(suppl 19):SII-65. Abstract.
23. Moldovan NI, Asahara T. Role of blood mononuclear cells in recanalization and vascularization of thrombi: past, present, and future. Trends Cardiovasc Med. 2003:13:265-269.
24. Peters KG, De Vries C, Williams LT. Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth. Proc Natl Acad Sci U S A. 1993;90:8915-8919.
25. Oelrichs RB, Reid HH, Bernard O, Ziemiecki A, Wilks AF. NYK/FLK-1: a putative receptor protein tyrosine kinase isolated from E10 embryonic neuroepithelium is expressed in endothelial cells of the developing embryo. Oncogene. 1993;8:11-18.
26. Shibata Y, Zsengeller Z, Otake K, Palaniyar N, Trapnell BC. Alveolar macrophage deficiency in osteopetrotic mice deficient in macrophage colony-stimulating factor is spontaneously corrected with age and associated with matrix metalloproteinase expression and emphysema. Blood. 2001;98:2845-2852.
27. Choi K, Kennedy M, Kazarov A, Papadimitriou JC, Keller G. A common precursor for hematopoietic and endothelial cells. Development. 1998; 125:725-732.
28. Shaw JP, Basch R, Shamamian P. Hematopoietic stem cells and endothelial cell precursors express Tie-2, CD31 and CD45. Blood Cells Mol Dis. 2004;32:168-175.
29. Zhao Y, Glesne D, Huberman E. A human peripheral blood monocytederived subset acts as pluripotent stem cells. Proc Natl Acad Sci U S A, 2003;100:2426-2431.
30. Rehman J, Li J, Orschell CM, March KL. Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors. Circulation. 2003;107:1164-1169.
31. Fujiyama S, Amano K, Uehira K, Yoshida M, Nishiwaki Y, Nozawa Y, Jin D, Takai S, Miyazaki M, Egashira K, Imada T, Iwasaka T, Matsubara H, Bone marrow monocyte lineage cells adhere on injured endothelium in a monocyte chemoattractant protein-1 -dependent manner and accelerate reendothelialization as endothelial progenitor cells. Circ Res. 2003;93: 980-989.
32. Schmeisser A, Garlichs CD, Zhang H, Eskafi S, Graffy C, Ludwig J, Strasser RH, Daniel WG. Monocytes coexpress endothelial and macrophagocytic lineage markers and form cord-like structures in Matrigel under angiogenic conditions. Cardiovasc Res. 2001;49:671-680.
33. Voswinckel R, Ziegelhoeffer T, Heil M, Kostin S, Breier G, Mehling T, Haberberger R, Clauss M, Gaumann A, Schaper W, Seeger W. Circulating vascular progenitor cells do not contribute to compensatory lung growth. Circ Res. 2003;93:372-379.
34. Murohara T, Ikeda H, Duan J, Shintani S, Sasaki K, Eguchi H, Onitsuka I, Matsui K, Imaizumi T. Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularization. J Clin Invest. 2000; 105;1527-1536.
35. Urbich C, Heeschen C, Aicher A, Dernbach E, Zeiher AM, Dimmeler S. Relevance of monocytic features for neovascularization capacity of circulating endothelial progenitor cells. Circulation. 2003;108: 2511-2516.
36. Urbich C, Dimmeler S, Endothelial progenitor cells: characterization and role in vascular biology. Circ Res. 2004;95:343-353.
37. Woywodt A, Bahlmann FH, De Groot K, Haller H, Haubitz M. Circulating endothelial cells: life, death, detachment and repair of the endothelial cell layer. Nephrol Dial Transplant. 2002;17:1728-1730.