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Volumn 57, Issue 3, 2014, Pages 623-632

Magnitude and mechanisms of glucose counterregulation following islet transplantation in patients with type 1 diabetes suffering from severe hypoglycaemic episodes

Author keywords

Hypoglycaemia counterregulation; Pancreatic islet transplantation; Type 1 diabetes mellitus

Indexed keywords

GLUCOSE; GLUCOSE BLOOD LEVEL; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN; LACTIC ACID;

EID: 84894536916     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-013-3120-9     Document Type: Article
Times cited : (21)

References (31)
  • 1
    • 57249098943 scopus 로고    scopus 로고
    • The barrier of hypoglycemia in diabetes
    • 1:CAS:528:DC%2BD1MXhsleisLY%3D 19033403 10.2337/db08-1084
    • Cryer PE (2008) The barrier of hypoglycemia in diabetes. Diabetes 57:3169-3176
    • (2008) Diabetes , vol.57 , pp. 3169-3176
    • Cryer, P.E.1
  • 3
    • 41149105804 scopus 로고    scopus 로고
    • Hypoglycemia in type 1 diabetes: A still unresolved problem in the era of insulin analogs and pump therapy
    • 18227471 10.2337/dc08-s228
    • Shalitin S, Phillip M (2008) Hypoglycemia in type 1 diabetes: a still unresolved problem in the era of insulin analogs and pump therapy. Diabetes Care 31(Suppl 2):S121-S124
    • (2008) Diabetes Care , vol.31 , Issue.SUPPL. 2
    • Shalitin, S.1    Phillip, M.2
  • 4
    • 21344462346 scopus 로고    scopus 로고
    • Five-year follow-up after clinical islet transplantation
    • 1:CAS:528:DC%2BD2MXmtVelsbs%3D 15983207 10.2337/diabetes.54.7.2060
    • Ryan EA, Paty BW, Senior PA et al (2005) Five-year follow-up after clinical islet transplantation. Diabetes 54:2060-2069
    • (2005) Diabetes , vol.54 , pp. 2060-2069
    • Ryan, E.A.1    Paty, B.W.2    Senior, P.A.3
  • 5
    • 59249108588 scopus 로고    scopus 로고
    • Restoration of hypoglycemia awareness after islet transplantation
    • 18697903 10.2337/dc08-0741
    • Leitão CB, Tharavanij T, Cure P et al (2008) Restoration of hypoglycemia awareness after islet transplantation. Diabetes Care 31:2113-2115
    • (2008) Diabetes Care , vol.31 , pp. 2113-2115
    • Leitão, C.B.1    Tharavanij, T.2    Cure, P.3
  • 6
    • 84862892304 scopus 로고    scopus 로고
    • Improvement in outcomes of clinical islet transplantation: 1999-2010
    • 1:CAS:528:DC%2BC38Xht1Sht7rL 22723582 10.2337/dc12-0063
    • Barton FB, Rickels MR, Alejandro R et al (2012) Improvement in outcomes of clinical islet transplantation: 1999-2010. Diabetes Care 35:1436-1445
    • (2012) Diabetes Care , vol.35 , pp. 1436-1445
    • Barton, F.B.1    Rickels, M.R.2    Alejandro, R.3
  • 7
    • 84879553051 scopus 로고    scopus 로고
    • Multicenter Australian trial of islet transplantation: Improving accessibility and outcomes
    • 23668890 10.1111/ajt.12250
    • O'Connell PJ, Holmes-Walker DJ, Goodman D et al (2013) Multicenter Australian trial of islet transplantation: improving accessibility and outcomes. Am J Transplant 13:1850-1858
    • (2013) Am J Transplant , vol.13 , pp. 1850-1858
    • O'Connell, P.J.1    Holmes-Walker, D.J.2    Goodman, D.3
  • 8
    • 0024834748 scopus 로고
    • Lilly lecture 1989. Toward physiological understanding of glucose tolerance. Minimal-model approach
    • 1:CAS:528:DyaK3cXjtVKqtg%3D%3D 2684710 10.2337/diab.38.12.1512
    • Bergman RN (1989) Lilly lecture 1989. Toward physiological understanding of glucose tolerance. Minimal-model approach. Diabetes 38:1512-1527
    • (1989) Diabetes , vol.38 , pp. 1512-1527
    • Bergman, R.N.1
  • 9
    • 27744554445 scopus 로고    scopus 로고
    • A potential important role of skeletal muscle in human counterregulation of hypoglycemia
    • 1:CAS:528:DC%2BD2MXht1altL7F 16144954 10.1210/jc.2005-0225
    • Meyer C, Saar P, Soydan N et al (2005) A potential important role of skeletal muscle in human counterregulation of hypoglycemia. J Clin Endocrinol Metab 90:6244-6250
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 6244-6250
    • Meyer, C.1    Saar, P.2    Soydan, N.3
  • 10
    • 0032558096 scopus 로고    scopus 로고
    • Improved glucose counterregulation and autonomic symptoms after intraportal islet transplants alone in patients with long-standing type i diabetes mellitus
    • 1:STN:280:DyaK1czmsFSjsw%3D%3D 9701271 10.1097/00007890-199807270-00017
    • Meyer C, Hering BJ, Grossmann R et al (1998) Improved glucose counterregulation and autonomic symptoms after intraportal islet transplants alone in patients with long-standing type I diabetes mellitus. Transplantation 66:233-240
    • (1998) Transplantation , vol.66 , pp. 233-240
    • Meyer, C.1    Hering, B.J.2    Grossmann, R.3
  • 11
    • 33947509294 scopus 로고    scopus 로고
    • Glycemic thresholds for activation of counterregulatory hormone and symptom responses in islet transplant recipients
    • 1:CAS:528:DC%2BD2sXjtlGnurk%3D 17192287 10.1210/jc.2006-2426
    • Rickels MR, Schutta MH, Mueller R et al (2007) Glycemic thresholds for activation of counterregulatory hormone and symptom responses in islet transplant recipients. J Clin Endocrinol Metab 92:873-879
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 873-879
    • Rickels, M.R.1    Schutta, M.H.2    Mueller, R.3
  • 12
    • 33644673813 scopus 로고    scopus 로고
    • Islet cell hormonal responses to hypoglycemia after human islet transplantation for type 1 diabetes
    • 1:CAS:528:DC%2BD2MXht1Siu7fF 16249446 10.2337/diabetes.54.11.3205
    • Rickels MR, Schutta MH, Mueller R et al (2005) Islet cell hormonal responses to hypoglycemia after human islet transplantation for type 1 diabetes. Diabetes 54:3205-3211
    • (2005) Diabetes , vol.54 , pp. 3205-3211
    • Rickels, M.R.1    Schutta, M.H.2    Mueller, R.3
  • 13
    • 0031006603 scopus 로고    scopus 로고
    • Hypoglycemia in the Diabetes Control and Complications Trial
    • The Diabetes Control and Complications Trial Research Group 10.2337/diab.46.2.271
    • The Diabetes Control and Complications Trial Research Group (1997) Hypoglycemia in the Diabetes Control and Complications Trial. Diabetes 46:271-286
    • (1997) Diabetes , vol.46 , pp. 271-286
  • 14
    • 0034721255 scopus 로고    scopus 로고
    • Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
    • 1:CAS:528:DC%2BD3cXlvVSmt7k%3D 10911004 10.1056/NEJM200007273430401
    • Shapiro AM, Lakey JR, Ryan EA et al (2000) Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 343:230-238
    • (2000) N Engl J Med , vol.343 , pp. 230-238
    • Shapiro, A.M.1    Lakey, J.R.2    Ryan, E.A.3
  • 16
    • 78651144990 scopus 로고
    • On the hormonal regulation of carbohydrate metabolism; Studies with C14 glucose
    • 1:CAS:528:DyaF3sXkslSiurg%3D 14284029
    • Debodo RC, Steele R, Altszuler N, Dunn A, Bishop JS (1963) On the hormonal regulation of carbohydrate metabolism; studies with C14 glucose. Recent Prog Horm Res 19:445-488
    • (1963) Recent Prog Horm Res , vol.19 , pp. 445-488
    • Debodo, R.C.1    Steele, R.2    Altszuler, N.3    Dunn, A.4    Bishop, J.S.5
  • 17
    • 0023245416 scopus 로고
    • Estimation of endogenous glucose production during hyperinsulinemic- euglycemic glucose clamps. Comparison of unlabeled and labeled exogenous glucose infusates
    • 1:CAS:528:DyaL2sXlslWrt7g%3D 3297886 10.2337/diab.36.8.914
    • Finegood DT, Bergman RN, Vranic M (1987) Estimation of endogenous glucose production during hyperinsulinemic-euglycemic glucose clamps. Comparison of unlabeled and labeled exogenous glucose infusates. Diabetes 36:914-924
    • (1987) Diabetes , vol.36 , pp. 914-924
    • Finegood, D.T.1    Bergman, R.N.2    Vranic, M.3
  • 18
    • 0016213628 scopus 로고
    • Measurement and validation of nonsteady turnover rates with applications to the inulin and glucose systems
    • 1:CAS:528:DyaE2cXkvVOnt7g%3D 4834189
    • Radziuk J, Norwich KH, Vranic M (1974) Measurement and validation of nonsteady turnover rates with applications to the inulin and glucose systems. Fed Proc 33:1855-1864
    • (1974) Fed Proc , vol.33 , pp. 1855-1864
    • Radziuk, J.1    Norwich, K.H.2    Vranic, M.3
  • 19
    • 0017250446 scopus 로고
    • Lactate metabolism in resting and exercising dogs
    • 1:CAS:528:DyaE28XhtF2ntr0%3D 931842
    • Issekutz B Jr, Shaw WA, Issekutz AC (1976) Lactate metabolism in resting and exercising dogs. J Appl Physiol 40:312-319
    • (1976) J Appl Physiol , vol.40 , pp. 312-319
    • Issekutz, Jr.B.1    Shaw, W.A.2    Issekutz, A.C.3
  • 21
    • 0026717602 scopus 로고
    • Nonproductive exchanges: The use of isotopes gone astray
    • 1:CAS:528:DyaK38XhvFSms7g%3D 1588822 10.1016/0026-0495(92)90199-K
    • Landau BR, Wahren J (1992) Nonproductive exchanges: the use of isotopes gone astray. Metabolism 41:457-459
    • (1992) Metabolism , vol.41 , pp. 457-459
    • Landau, B.R.1    Wahren, J.2
  • 22
    • 0026512255 scopus 로고
    • Skeletal muscle is a major site of lactate uptake and release during hyperinsulinemia
    • 1:CAS:528:DyaK38Xls1KgtA%3D%3D 1736040 10.1016/0026-0495(92)90148-4
    • Consoli A, Nurjahan N, Gerich JE, Mandarino LJ (1992) Skeletal muscle is a major site of lactate uptake and release during hyperinsulinemia. Metabolism 41:176-179
    • (1992) Metabolism , vol.41 , pp. 176-179
    • Consoli, A.1    Nurjahan, N.2    Gerich, J.E.3    Mandarino, L.J.4
  • 23
    • 0019921815 scopus 로고
    • Muscle mass: Reliable indicator of protein-energy malnutrition severity and outcome
    • 1:CAS:528:DyaL38XktVCqtLc%3D 6805298
    • Heymsfield SB, McManus C, Stevens V, Smith J (1982) Muscle mass: reliable indicator of protein-energy malnutrition severity and outcome. Am J Clin Nutr 35:1192-1199
    • (1982) Am J Clin Nutr , vol.35 , pp. 1192-1199
    • Heymsfield, S.B.1    McManus, C.2    Stevens, V.3    Smith, J.4
  • 24
    • 0031036141 scopus 로고    scopus 로고
    • Defective glucagon secretion during sustained hypoglycemia following successful islet allo- and autotransplantation in humans
    • 1:CAS:528:DyaK2sXks1aq 8971076 10.2337/diab.46.1.23
    • Kendall DM, Teuscher AU, Robertson RP (1997) Defective glucagon secretion during sustained hypoglycemia following successful islet allo- and autotransplantation in humans. Diabetes 46:23-27
    • (1997) Diabetes , vol.46 , pp. 23-27
    • Kendall, D.M.1    Teuscher, A.U.2    Robertson, R.P.3
  • 25
    • 0036896935 scopus 로고    scopus 로고
    • Intrahepatic islet transplantation in type 1 diabetic patients does not restore hypoglycemic hormonal counterregulation or symptom recognition after insulin independence
    • 1:CAS:528:DC%2BD38Xptl2nurw%3D 12453896 10.2337/diabetes.51.12.3428
    • Paty BW, Ryan EA, Shapiro AM, Lakey JR, Robertson RP (2002) Intrahepatic islet transplantation in type 1 diabetic patients does not restore hypoglycemic hormonal counterregulation or symptom recognition after insulin independence. Diabetes 51:3428-3434
    • (2002) Diabetes , vol.51 , pp. 3428-3434
    • Paty, B.W.1    Ryan, E.A.2    Shapiro, A.M.3    Lakey, J.R.4    Robertson, R.P.5
  • 26
    • 0028961526 scopus 로고
    • Contribution of hepatic glycogenolysis to glucose production in humans in response to a physiological increase in plasma glucagon concentration
    • 1:CAS:528:DyaK2MXjtlCksL8%3D 7859939 10.2337/diab.44.2.185
    • Magnusson I, Rothman DL, Gerard DP, Katz LD, Shulman GI (1995) Contribution of hepatic glycogenolysis to glucose production in humans in response to a physiological increase in plasma glucagon concentration. Diabetes 44:185-189
    • (1995) Diabetes , vol.44 , pp. 185-189
    • Magnusson, I.1    Rothman, D.L.2    Gerard, D.P.3    Katz, L.D.4    Shulman, G.I.5
  • 27
    • 0028847792 scopus 로고
    • Impaired net hepatic glycogen synthesis in insulin-dependent diabetic subjects during mixed meal ingestion. A 13C nuclear magnetic resonance spectroscopy study
    • 1:CAS:528:DyaK2MXjsV2rsLw%3D 7860761 10.1172/JCI117727 295553
    • Hwang JH, Perseghin G, Rothman DL et al (1995) Impaired net hepatic glycogen synthesis in insulin-dependent diabetic subjects during mixed meal ingestion. A 13C nuclear magnetic resonance spectroscopy study. J Clin Invest 95:783-787
    • (1995) J Clin Invest , vol.95 , pp. 783-787
    • Hwang, J.H.1    Perseghin, G.2    Rothman, D.L.3
  • 28
    • 0035143089 scopus 로고    scopus 로고
    • Effects of short-term improvement of insulin treatment and glycemia on hepatic glycogen metabolism in type 1 diabetes
    • 1:CAS:528:DC%2BD3MXhtVOgs7Y%3D 11272152 10.2337/diabetes.50.2.392
    • Bischof MG, Krssak M, Krebs M et al (2001) Effects of short-term improvement of insulin treatment and glycemia on hepatic glycogen metabolism in type 1 diabetes. Diabetes 50:392-398
    • (2001) Diabetes , vol.50 , pp. 392-398
    • Bischof, M.G.1    Krssak, M.2    Krebs, M.3
  • 29
    • 48249088124 scopus 로고    scopus 로고
    • Intrahepatic glucose flux as a mechanism for defective intrahepatic islet alpha-cell response to hypoglycemia
    • 1:CAS:528:DC%2BD1cXnsF2isr8%3D 18362210 10.2337/db08-0137
    • Zhou H, Zhang T, Bogdani M et al (2008) Intrahepatic glucose flux as a mechanism for defective intrahepatic islet alpha-cell response to hypoglycemia. Diabetes 57:1567-1574
    • (2008) Diabetes , vol.57 , pp. 1567-1574
    • Zhou, H.1    Zhang, T.2    Bogdani, M.3
  • 30
    • 77954933558 scopus 로고    scopus 로고
    • Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
    • 1:CAS:528:DC%2BC3cXovFarsbc%3D 20577053 10.1172/JCI40671 2898585
    • Foretz M, Hébrard S, Leclerc J et al (2010) Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state. J Clin Invest 120:2355-2369
    • (2010) J Clin Invest , vol.120 , pp. 2355-2369
    • Foretz, M.1    Hébrard, S.2    Leclerc, J.3
  • 31
    • 0042320958 scopus 로고    scopus 로고
    • Higher insulin concentrations are required to suppress gluconeogenesis than glycogenolysis in nondiabetic humans
    • 1:CAS:528:DC%2BD3sXntFeqtLk%3D 12941759 10.2337/diabetes.52.9.2213
    • Adkins A, Basu R, Persson M et al (2003) Higher insulin concentrations are required to suppress gluconeogenesis than glycogenolysis in nondiabetic humans. Diabetes 52:2213-2220
    • (2003) Diabetes , vol.52 , pp. 2213-2220
    • Adkins, A.1    Basu, R.2    Persson, M.3


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