An antimicrobial helix A-derived peptide of heparin cofactor II blocks endotoxin responses in vivo

Biochimica et Biophysica Acta - Biomembranes

Volumn 1838, Issue 5, 2014, Pages 1225-1234

  Papareddy, Praveen ^a   Kalle, Martina ^a   Singh, Shalini ^b   Mörgelin, Matthias ^a   Schmidtchen, Artur ^a,c   Malmsten, Martin ^b  

^a LUND UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

^c NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

Antimicrobial peptide; Lipid A; Lipopolysaccharide; Membrane

Indexed keywords

ANTIINFECTIVE AGENT; BACTERIUM LIPOPOLYSACCHARIDE; ENDOTOXIN; HEPARIN COFACTOR II; LIPID A; PEPTIDE GKS26; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BIOASSAY; BIOLOGICAL ACTIVITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; HOST RESISTANCE; IN VITRO STUDY; IN VIVO STUDY; LIPID MEMBRANE; LUNG INFILTRATE; MEMBRANE DAMAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LIPID INTERACTION; SEPTIC SHOCK;

BACTERIA (MICROORGANISMS); MUS;

ANTIMICROBIAL PEPTIDE; LIPID A; LIPOPOLYSACCHARIDE; MEMBRANE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIA; CELL LINE; CELL MEMBRANE; CYTOKINES; ENDOTOXINS; HEPARIN COFACTOR II; HUMANS; INFLAMMATION; LIPIDS; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED C57BL; PROTEIN STRUCTURE, TERTIARY; SHOCK, SEPTIC;

EID: 84894536600     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2014.01.026     Document Type: Article

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