The C-terminal sequence of several human serine proteases encodes host defense functions

Journal of Innate Immunity

Volumn 3, Issue 5, 2011, Pages 471-482

  Kasetty, Gopinath ^a   Papareddy, Praveen ^a   Kalle, Martina ^a   Rydengrd, Victoria ^a   Walse, Björn ^c   Svensson, Bo ^c   Mörgelin, Matthias ^b   Malmsten, Martin ^d   Schmidtchen, Artur ^a  

^a LUND UNIVERSITY   (Sweden)

^b LUND UNIVERSITY   (Sweden)

^c SARomics AB   (Sweden)

^d UPPSALA UNIVERSITY   (Sweden)

Author keywords

Antimicrobial peptide; Coagulation; Endotoxin; Host defense; Proteinase

Indexed keywords

APOLIPOPROTEIN; BACTERIUM LIPOPOLYSACCHARIDE; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 9; CATHEPSIN G; GRANZYME B; HYALURONIC ACID BINDING PROTEIN; KALLIKREIN; LIPOSOME; NEUROPSIN; PLASMINOGEN; POLYPEPTIDE ANTIBIOTIC AGENT; PROTEIN C; SERINE PROTEINASE; THROMBIN;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; ARTICLE; BLOOD CELL; BLOOD CLOTTING; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EPITHELIUM CELL; HOST RESISTANCE; HUMAN; IMMUNOMODULATION; INNATE IMMUNITY; MACROPHAGE FUNCTION; MALE; MEMBRANE PERMEABILITY; MOUSE; NONHUMAN; PHYSIOLOGICAL PROCESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; SEPTIC SHOCK;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; CELL LINE; DISEASE MODELS, ANIMAL; HUMANS; IMMUNITY, INNATE; IMMUNOMODULATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED C57BL; PEPTIDE FRAGMENTS; PHYLOGENY; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SERINE PROTEASES; SHOCK, SEPTIC; STRUCTURAL HOMOLOGY, PROTEIN;

EID: 80052048215     PISSN: 1662811X     EISSN: 16628128     Source Type: Journal    
DOI: 10.1159/000327016     Document Type: Article

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