-
1
-
-
79952232216
-
Global cancer statistics
-
Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin 2011; 61:69-90.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
2
-
-
0035135578
-
Adjuvant treatment of colorectal cancer at the turn of the century: European and US perspectives
-
Wils J, O'Dwyer P, Labianca R. Adjuvant treatment of colorectal cancer at the turn of the century: European and US perspectives. Ann Oncol 2001; 12:13-22.
-
(2001)
Ann Oncol
, vol.12
, pp. 13-22
-
-
Wils, J.1
O'Dwyer, P.2
Labianca, R.3
-
4
-
-
36448978124
-
TNF-alpha is critical for antitumor but not antiviral T cell immunity in mice
-
Calzascia T, Pellegrini M, Hall H, et al. TNF-alpha is critical for antitumor but not antiviral T cell immunity in mice. J Clin Invest 2007; 117:3833-3845.
-
(2007)
J Clin Invest
, vol.117
, pp. 3833-3845
-
-
Calzascia, T.1
Pellegrini, M.2
Hall, H.3
-
5
-
-
0141431027
-
Tumour necrosis factor alpha: A potential target for the therapy of solid tumours
-
Szlosarek PW, Balkwill FR. Tumour necrosis factor alpha: A potential target for the therapy of solid tumours. Lancet Oncol 2003; 4:565-573.
-
(2003)
Lancet Oncol
, vol.4
, pp. 565-573
-
-
Szlosarek, P.W.1
Balkwill, F.R.2
-
6
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
Karin M. Nuclear factor-kappaB in cancer development and progression. Nature 2006; 441:431-436.
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
7
-
-
33645703930
-
Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation
-
Wu CJ, Conze DB, Li T, Srinivasula SM, Ashwell JD. Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation. Nat Cell Biol 2006; 8:398-406.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 398-406
-
-
Wu, C.J.1
Conze, D.B.2
Li, T.3
Srinivasula, S.M.4
Ashwell, J.D.5
-
8
-
-
81255195542
-
Programmed necrosis: Backup to and competitor with apoptosis in the immune system
-
Han J, Zhong CQ, Zhang DW. Programmed necrosis: Backup to and competitor with apoptosis in the immune system. Nat Immunol 2011; 12:1143-1149.
-
(2011)
Nat Immunol
, vol.12
, pp. 1143-1149
-
-
Han, J.1
Zhong, C.Q.2
Zhang, D.W.3
-
9
-
-
8444220527
-
Molecular mechanisms of caspase regulation during apoptosis
-
Riedl SJ, Shi Y. Molecular mechanisms of caspase regulation during apoptosis. Nat Rev Mol Cell Biol 2004; 5:897-907.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 897-907
-
-
Riedl, S.J.1
Shi, Y.2
-
10
-
-
33845977959
-
Mitochondrial membrane permeabilization in cell death
-
Kroemer G, Galluzzi L, Brenner C. Mitochondrial membrane permeabilization in cell death. Physiol Rev 2007; 87:99-163.
-
(2007)
Physiol Rev
, vol.87
, pp. 99-163
-
-
Kroemer, G.1
Galluzzi, L.2
Brenner, C.3
-
11
-
-
0036009115
-
NF-kappaB at the crossroads of life and death
-
Karin M, Lin A. NF-kappaB at the crossroads of life and death. Nat Immunol 2002; 3:221-227.
-
(2002)
Nat Immunol
, vol.3
, pp. 221-227
-
-
Karin, M.1
Lin, A.2
-
12
-
-
33847745864
-
Execution of macrophage apoptosis by PE_PGRS33 of Mycobacterium tuberculosis is mediated by Toll-like receptor 2-dependent release of tumor necrosis factor-alpha
-
Basu S, Pathak SK, Banerjee A, et al. Execution of macrophage apoptosis by PE_PGRS33 of Mycobacterium tuberculosis is mediated by Toll-like receptor 2-dependent release of tumor necrosis factor-alpha. J Biol Chem 2007; 282:1039-1050.
-
(2007)
J Biol Chem
, vol.282
, pp. 1039-1050
-
-
Basu, S.1
Pathak, S.K.2
Banerjee, A.3
-
13
-
-
0033576675
-
More than one way to die: Apoptosis, necrosis and reactive oxygen damage
-
Fiers W, Beyaert R, Declercq W, Vandenabeele P. More than one way to die: Apoptosis, necrosis and reactive oxygen damage. Oncogene 1999; 18:7719-7730.
-
(1999)
Oncogene
, vol.18
, pp. 7719-7730
-
-
Fiers, W.1
Beyaert, R.2
Declercq, W.3
Vandenabeele, P.4
-
14
-
-
0034986183
-
Activation of two distinct anti-proliferative pathways, apoptosis and p38 MAP kinase-dependent cell cycle arrest, by tumor necrosis factor in human melanoma cell line A375
-
Hattori T, Hayashi H, Chiba T, Onozaki K. Activation of two distinct anti-proliferative pathways, apoptosis and p38 MAP kinase-dependent cell cycle arrest, by tumor necrosis factor in human melanoma cell line A375. Eur Cytokine Netw 2001; 12:244-252.
-
(2001)
Eur Cytokine Netw
, vol.12
, pp. 244-252
-
-
Hattori, T.1
Hayashi, H.2
Chiba, T.3
Onozaki, K.4
-
15
-
-
34248141100
-
Cytokine-mediated A between link innate immunity inflammation, and cancer
-
Lin WW, Karin M. Cytokine-mediated A between link innate immunity inflammation, and cancer. J Clin Invest 2007; 117:1175-1183.
-
(2007)
J Clin Invest
, vol.117
, pp. 1175-1183
-
-
Lin, W.W.1
Karin, M.2
-
16
-
-
33845546703
-
The involvement of IL-1 in tumorigenesis, tumor invasiveness, metastasis and tumor-host interactions
-
Apte RN, Dotan S, Elkabets M, et al. The involvement of IL-1 in tumorigenesis, tumor invasiveness, metastasis and tumor-host interactions. Cancer Metastasis Rev 2006; 25:387-408.
-
(2006)
Cancer Metastasis Rev
, vol.25
, pp. 387-408
-
-
Apte, R.N.1
Dotan, S.2
Elkabets, M.3
-
17
-
-
23644436122
-
IL-6 signaling promotes tumor growth in colorectal cancer
-
Becker C, Fantini MC, Wirtz S, et al. IL-6 signaling promotes tumor growth in colorectal cancer. Cell Cycle 2005; 4:217-220.
-
(2005)
Cell Cycle
, vol.4
, pp. 217-220
-
-
Becker, C.1
Fantini, M.C.2
Wirtz, S.3
-
18
-
-
54049086233
-
Interleukin-8 signaling attenuates TRAIL- and chemotherapy-induced apoptosis through transcriptional regulation of c-FLIP in prostate cancer cells
-
Wilson C, Wilson T, Johnston PG, Longley DB, Waugh DJ. Interleukin-8 signaling attenuates TRAIL- and chemotherapy-induced apoptosis through transcriptional regulation of c-FLIP in prostate cancer cells. Mol Cancer Ther 2008; 7:2649-2661.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 2649-2661
-
-
Wilson, C.1
Wilson, T.2
Johnston, P.G.3
Longley, D.B.4
Waugh, D.J.5
-
19
-
-
0042014500
-
Interleukin-10-mediated inhibition of angiogenesis and tumor growth in mice bearing VEGF-producing ovarian cancer
-
Kohno T, Mizukami H, Suzuki M, et al. Interleukin-10-mediated inhibition of angiogenesis and tumor growth in mice bearing VEGF-producing ovarian cancer. Cancer Res 2003; 63:5091-5094.
-
(2003)
Cancer Res
, vol.63
, pp. 5091-5094
-
-
Kohno, T.1
Mizukami, H.2
Suzuki, M.3
-
20
-
-
18644381517
-
Expression of IL-27 in murine carcinoma cells produces antitumor effects and induces protective immunity in inoculated host animals
-
Chiyo M, Shimozato O, Yu L, et al. Expression of IL-27 in murine carcinoma cells produces antitumor effects and induces protective immunity in inoculated host animals. Int J Cancer 2005; 115:437-442.
-
(2005)
Int J Cancer
, vol.115
, pp. 437-442
-
-
Chiyo, M.1
Shimozato, O.2
Yu, L.3
-
21
-
-
0037731516
-
Synergistic therapeutic effects of a tumor targeting antibody fragment, fused to interleukin 12 and to tumor necrosis factor alpha
-
Halin C, Gafner V, Villani ME, et al. Synergistic therapeutic effects of a tumor targeting antibody fragment, fused to interleukin 12 and to tumor necrosis factor alpha. Cancer Res 2003; 63:3202-3210.
-
(2003)
Cancer Res
, vol.63
, pp. 3202-3210
-
-
Halin, C.1
Gafner, V.2
Villani, M.E.3
-
22
-
-
33745618676
-
IL-4 inhibits the TNF-alpha induced proliferation of renal cell carcinoma (RCC) and cooperates with TNF-alpha to induce apoptotic and cytokine responses by RCC: Implications for antitumor immune responses
-
Falkensammer C, Johrer K, Gander H, et al. IL-4 inhibits the TNF-alpha induced proliferation of renal cell carcinoma (RCC) and cooperates with TNF-alpha to induce apoptotic and cytokine responses by RCC: Implications for antitumor immune responses. Cancer Immunol Immunother 2006; 55:1228-1237.
-
(2006)
Cancer Immunol Immunother
, vol.55
, pp. 1228-1237
-
-
Falkensammer, C.1
Johrer, K.2
Gander, H.3
-
23
-
-
12444304581
-
Interleukin-32: A cytokine and inducer of TNFalpha
-
Kim SH, Han SY, Azam T, Yoon DY, Dinarello CA. Interleukin-32: A cytokine and inducer of TNFalpha. Immunity 2005; 22:131-142.
-
(2005)
Immunity
, vol.22
, pp. 131-142
-
-
Kim, S.H.1
Han, S.Y.2
Azam, T.3
Yoon, D.Y.4
Dinarello, C.A.5
-
24
-
-
31544432072
-
Involvement of IL-32 in activation-induced cell death in T cells
-
Goda C, Kanaji T, Kanaji S, et al. Involvement of IL-32 in activation-induced cell death in T cells. Int Immunol 2006; 18:233-240.
-
(2006)
Int Immunol
, vol.18
, pp. 233-240
-
-
Goda, C.1
Kanaji, T.2
Kanaji, S.3
-
25
-
-
42949095542
-
Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function
-
Marcondes AM, Mhyre AJ, Stirewalt DL, Kim SH, Dinarello CA, Deeg HJ. Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function. Proc Natl Acad Sci USA 2008; 105:2865-2870.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 2865-2870
-
-
Marcondes, A.M.1
Mhyre, A.J.2
Stirewalt, D.L.3
Kim, S.H.4
Dinarello, C.A.5
Deeg, H.J.6
-
26
-
-
61449091573
-
Identification of the most active interleukin-32 isoform
-
Choi JD, Bae SY, Hong JW, et al. Identification of the most active interleukin-32 isoform. Immunology 2009; 126:535-542.
-
(2009)
Immunology
, vol.126
, pp. 535-542
-
-
Choi, J.D.1
Bae, S.Y.2
Hong, J.W.3
-
27
-
-
79960838180
-
IL-32gamma inhibits cancer cell growth through inactivation of NF-kappaB and STAT3 signals
-
Oh JH, Cho MC, Kim JH, et al. IL-32gamma inhibits cancer cell growth through inactivation of NF-kappaB and STAT3 signals. Oncogene 2011; 30:3345-3359.
-
(2011)
Oncogene
, vol.30
, pp. 3345-3359
-
-
Oh, J.H.1
Cho, M.C.2
Kim, J.H.3
-
28
-
-
66249116702
-
PI3K pathway activation mediates resistance to MEK inhibitors in KRAS mutant cancers
-
Wee S, Jagani Z, Xiang KX, et al. PI3K pathway activation mediates resistance to MEK inhibitors in KRAS mutant cancers. Cancer Res 2009; 69:4286-4293.
-
(2009)
Cancer Res
, vol.69
, pp. 4286-4293
-
-
Wee, S.1
Jagani, Z.2
Xiang, K.X.3
-
29
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995; 270:1326-1331.
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
30
-
-
34848813535
-
Varied role of the gut epithelium in mucosal homeostasis
-
McCole DF, Barrett KE. Varied role of the gut epithelium in mucosal homeostasis. Curr Opin Gastroenterol 2007; 23:647-654.
-
(2007)
Curr Opin Gastroenterol
, vol.23
, pp. 647-654
-
-
McCole, D.F.1
Barrett, K.E.2
-
31
-
-
4544224979
-
Inhibition of NF-kappaB in cancer cells converts inflammation-induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression
-
Luo JL, Maeda S, Hsu LC, Yagita H, Karin M. Inhibition of NF-kappaB in cancer cells converts inflammation-induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression. Cancer Cell 2004; 6:297-305.
-
(2004)
Cancer Cell
, vol.6
, pp. 297-305
-
-
Luo, J.L.1
Maeda, S.2
Hsu, L.C.3
Yagita, H.4
Karin, M.5
-
32
-
-
0027495327
-
The role of interleukin-6 in lipopolysaccharide-induced weight loss, hypoglycemia and fibrinogen production, in vivo
-
Strassmann G, Fong M, Windsor S, Neta R. The role of interleukin-6 in lipopolysaccharide-induced weight loss, hypoglycemia and fibrinogen production, in vivo. Cytokine 1993; 5:285-290.
-
(1993)
Cytokine
, vol.5
, pp. 285-290
-
-
Strassmann, G.1
Fong, M.2
Windsor, S.3
Neta, R.4
-
33
-
-
0030719401
-
Antitumor effects of the combination immunotherapy with interleukin-12 and tumor necrosis factor alpha in mice
-
Lasek W, Feleszko W, Golab J, et al. Antitumor effects of the combination immunotherapy with interleukin-12 and tumor necrosis factor alpha in mice. Cancer Immunol Immunother 1997; 45:100-108.
-
(1997)
Cancer Immunol Immunother
, vol.45
, pp. 100-108
-
-
Lasek, W.1
Feleszko, W.2
Golab, J.3
-
34
-
-
33749864535
-
The antitumor activity of TRAIL and IL-24 with replicating oncolytic adenovirus in colorectal cancer
-
Zhao L, Dong A, Gu J, et al. The antitumor activity of TRAIL and IL-24 with replicating oncolytic adenovirus in colorectal cancer. Cancer Gene Ther 2006; 13:1011-1022.
-
(2006)
Cancer Gene Ther
, vol.13
, pp. 1011-1022
-
-
Zhao, L.1
Dong, A.2
Gu, J.3
-
35
-
-
0028943734
-
Apoptosis in the pathogenesis and treatment of disease
-
Thompson CB. Apoptosis in the pathogenesis and treatment of disease. Science 1995; 267:1456-1462.
-
(1995)
Science
, vol.267
, pp. 1456-1462
-
-
Thompson, C.B.1
-
36
-
-
19944433954
-
Interleukin-10 plasmid DNA inhibits subcutaneous tumor growth of Colon 26 adenocarcinoma in mice
-
Kokura S, Yoshida N, Ishikawa T, et al. Interleukin-10 plasmid DNA inhibits subcutaneous tumor growth of Colon 26 adenocarcinoma in mice. Cancer Lett 2005; 218:171-179.
-
(2005)
Cancer Lett
, vol.218
, pp. 171-179
-
-
Kokura, S.1
Yoshida, N.2
Ishikawa, T.3
-
37
-
-
33745685704
-
Curcumin decreases binding of Shiga-like toxin-1B on human intestinal epithelial cell line HT29 stimulated with TNF-alpha and IL-1beta: Suppression of p38 JNK and NF-kappaB p65 as potential targets
-
Moon DO, Jin CY, Lee JD, et al. Curcumin decreases binding of Shiga-like toxin-1B on human intestinal epithelial cell line HT29 stimulated with TNF-alpha and IL-1beta: Suppression of p38 JNK and NF-kappaB p65 as potential targets. Biol Pharm Bull 2006; 29:1470-1475.
-
(2006)
Biol Pharm Bull
, vol.29
, pp. 1470-1475
-
-
Moon, D.O.1
Jin, C.Y.2
Lee, J.D.3
-
38
-
-
70849088411
-
Miz1 is a signal- and pathway-specific modulator or regulator (SMOR) that suppresses TNF-alpha-induced JNK1 activation
-
Liu J, Zhao Y, Eilers M, Lin A. Miz1 is a signal- and pathway-specific modulator or regulator (SMOR) that suppresses TNF-alpha-induced JNK1 activation. Proc Natl Acad Sci USA 2009; 106:18279-18284.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 18279-18284
-
-
Liu, J.1
Zhao, Y.2
Eilers, M.3
Lin, A.4
-
39
-
-
67349286984
-
Guggulsterone induces apoptosis in colon cancer cells and inhibits tumor growth in murine colorectal cancer xenografts
-
An MJ, Cheon JH, Kim SW, Kim ES, Kim TI, Kim WH. Guggulsterone induces apoptosis in colon cancer cells and inhibits tumor growth in murine colorectal cancer xenografts. Cancer Lett 2009; 279:93-100.
-
(2009)
Cancer Lett
, vol.279
, pp. 93-100
-
-
An, M.J.1
Cheon, J.H.2
Kim, S.W.3
Kim, E.S.4
Kim, T.I.5
Kim, W.H.6
-
40
-
-
40449127743
-
Action of bacterial polysaccharide on tumors. Iii. Repeated response of sarcoma 37, in tolerant mice, to serratia marcescens endotoxin
-
O'Malley WE, Achinstein B, Shear MJ. Action of bacterial polysaccharide on tumors. Iii. Repeated response of sarcoma 37, in tolerant mice, to serratia marcescens endotoxin. Cancer Res 1963; 23:890-895.
-
(1963)
Cancer Res
, vol.23
, pp. 890-895
-
-
O'Malley, W.E.1
Achinstein, B.2
Shear, M.J.3
-
41
-
-
0016723594
-
An endotoxin-induced serum factor that causes necrosis of tumors
-
Carswell EA, Old LJ, Kassel RL, Green S, Fiore N, Williamson B. An endotoxin-induced serum factor that causes necrosis of tumors. Proc Natl Acad Sci USA 1975; 72:3666-3670.
-
(1975)
Proc Natl Acad Sci USA
, vol.72
, pp. 3666-3670
-
-
Carswell, E.A.1
Old, L.J.2
Kassel, R.L.3
Green, S.4
Fiore, N.5
Williamson, B.6
-
42
-
-
0035292790
-
IL-6 and IFN-gamma regulation of IL-10 production by human colon carcinoma cells
-
Suzuki S, Mita S, Kamohara H, Sakamoto K, Ishiko T, Ogawa M. IL-6 and IFN-gamma regulation of IL-10 production by human colon carcinoma cells. Int J Oncol 2001; 18:581-586.
-
(2001)
Int J Oncol
, vol.18
, pp. 581-586
-
-
Suzuki, S.1
Mita, S.2
Kamohara, H.3
Sakamoto, K.4
Ishiko, T.5
Ogawa, M.6
-
43
-
-
68249158099
-
A proinflammatory cytokine interleukin-32beta promotes the production of an anti-inflammatory cytokine interleukin-10
-
Kang JW, Choi SC, Cho MC, et al. A proinflammatory cytokine interleukin-32beta promotes the production of an anti-inflammatory cytokine interleukin-10. Immunology 2009; 128:e532-e540.
-
(2009)
Immunology
, vol.128
-
-
Kang, J.W.1
Choi, S.C.2
Cho, M.C.3
-
44
-
-
78650425216
-
Paradoxical effects of constitutive human IL-32{gamma} in transgenic mice during experimental colitis
-
Choi J, Bae S, Hong J, et al. Paradoxical effects of constitutive human IL-32{gamma} in transgenic mice during experimental colitis. Proc Natl Acad Sci USA 2010; 107:21082-21086.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 21082-21086
-
-
Choi, J.1
Bae, S.2
Hong, J.3
-
45
-
-
83055176906
-
Interleukin-32 enhances cytotoxic effect of natural killer cells to cancer cells via activation of death receptor 3
-
Park MH, Song MJ, Cho MC, et al. Interleukin-32 enhances cytotoxic effect of natural killer cells to cancer cells via activation of death receptor 3. Immunology 2012; 135:63-72.
-
(2012)
Immunology
, vol.135
, pp. 63-72
-
-
Park, M.H.1
Song, M.J.2
Cho, M.C.3
-
46
-
-
0023693995
-
Tumor necrosis factor and lymphotoxin secretion by human natural killer cells leads to antiviral cytotoxicity
-
Paya CV, Kenmotsu N, Schoon RA, Leibson PJ. Tumor necrosis factor and lymphotoxin secretion by human natural killer cells leads to antiviral cytotoxicity. J Immunol 1988; 141:1989-1995.
-
(1988)
J Immunol
, vol.141
, pp. 1989-1995
-
-
Paya, C.V.1
Kenmotsu, N.2
Schoon, R.A.3
Leibson, P.J.4
-
47
-
-
0028962125
-
Fas-mediated cytotoxicity by freshly isolated natural killer cells
-
Arase H, Arase N, Saito T. Fas-mediated cytotoxicity by freshly isolated natural killer cells. J Exp Med 1995; 181:1235-1238.
-
(1995)
J Exp Med
, vol.181
, pp. 1235-1238
-
-
Arase, H.1
Arase, N.2
Saito, T.3
-
48
-
-
0030905897
-
A new mechanism of NK cell cytotoxicity activation: The CD40-CD40 ligand interaction
-
Carbone E, Ruggiero G, Terrazzano G, et al. A new mechanism of NK cell cytotoxicity activation: The CD40-CD40 ligand interaction. J Exp Med 1997; 185:2053-2060.
-
(1997)
J Exp Med
, vol.185
, pp. 2053-2060
-
-
Carbone, E.1
Ruggiero, G.2
Terrazzano, G.3
-
49
-
-
0032447111
-
Natural killer (NK) cell-mediated cytotoxicity: Differential use of TRAIL and Fas ligand by immature and mature primary human NK cells
-
Zamai L, Ahmad M, Bennett IM, Azzoni L, Alnemri ES, Perussia B. Natural killer (NK) cell-mediated cytotoxicity: Differential use of TRAIL and Fas ligand by immature and mature primary human NK cells. J Exp Med 1998; 188:2375-2380.
-
(1998)
J Exp Med
, vol.188
, pp. 2375-2380
-
-
Zamai, L.1
Ahmad, M.2
Bennett, I.M.3
Azzoni, L.4
Alnemri, E.S.5
Perussia, B.6
|