-
2
-
-
84862983912
-
The coumarin psoralidin enhances anticancer effect of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)
-
Bronikowska J, Szliszka E, Jaworska D, Czuba ZP and Krol W: The coumarin psoralidin enhances anticancer effect of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). Molecules 17: 6449-6464, 2012.
-
(2012)
Molecules
, vol.17
, pp. 6449-6464
-
-
Bronikowska, J.1
Szliszka, E.2
Jaworska, D.3
Czuba, Z.P.4
Krol, W.5
-
3
-
-
69949153861
-
Furanocoumarins: Novel topoisomerase I inhibitors from Ruta graveolens L
-
Diwan R and Malpathak N: Furanocoumarins: novel topoisomerase I inhibitors from Ruta graveolens L. Bioorg Med Chem 17: 7052-7055, 2009.
-
(2009)
Bioorg Med Chem
, vol.17
, pp. 7052-7055
-
-
Diwan, R.1
Malpathak, N.2
-
4
-
-
0033913305
-
Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco-2 cells and on the activity of cytochrome P450 3A4
-
Ohnishi A, Matsuo H, Yamada S, et al: Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco-2 cells and on the activity of cytochrome P450 3A4. Br Pharmacol 130: 1369-1377, 2000.
-
(2000)
Br Pharmacol
, vol.130
, pp. 1369-1377
-
-
Ohnishi, A.1
Matsuo, H.2
Yamada, S.3
-
5
-
-
33745159659
-
A furanocoumarin-free grapefruit juice establishes furanocoumarins as the mediators of the grapefruit juice-felodipine interaction
-
Paine MF, Widmer WW, Hart HL, et al: A furanocoumarin-free grapefruit juice establishes furanocoumarins as the mediators of the grapefruit juice-felodipine interaction. Am J Clin Nutr 83: 1097-1105, 2006.
-
(2006)
Am J Clin Nutr
, vol.83
, pp. 1097-1105
-
-
Paine, M.F.1
Widmer, W.W.2
Hart, H.L.3
-
6
-
-
0028117270
-
Drug resistance: Genotype versus phenotype - Thirty-second G.H.A. Clowes Memorial Award Lecture
-
Biedler JL: Drug resistance: genotype versus phenotype - Thirty-second G.H.A. Clowes Memorial Award Lecture. Cancer Res 54: 666-678, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 666-678
-
-
Biedler, J.L.1
-
7
-
-
0030577119
-
P-glycoprotein multidrug resistance and cancer
-
Bosch I and Croop J: P-glycoprotein multidrug resistance and cancer. Biochim Biophys Acta 9: 37-54, 1996.
-
(1996)
Biochim Biophys Acta
, vol.9
, pp. 37-54
-
-
Bosch, I.1
Croop, J.2
-
8
-
-
0024548599
-
Expression of a multidrug resistance gene in human cancers
-
Goldstein LJ, Galski H, Fojo A, et al: Expression of a multidrug resistance gene in human cancers. J Natl Cancer Inst 81: 116-124, 1989.
-
(1989)
J Natl Cancer Inst
, vol.81
, pp. 116-124
-
-
Goldstein, L.J.1
Galski, H.2
Fojo, A.3
-
9
-
-
0036364467
-
Multidrug resistance in cancer: Role of ATP-dependent transporters
-
Gottesman MM, Fojo T and Bates SE: Multidrug resistance in cancer: role of ATP-dependent transporters. Nat Rev Cancer 2: 48-58, 2002.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 48-58
-
-
Gottesman, M.M.1
Fojo, T.2
Bates, S.E.3
-
10
-
-
0035901938
-
Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance
-
Friedrich K, Wieder T, Von Haefen C, et al: Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance. Oncogene 20: 2749-2760, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 2749-2760
-
-
Friedrich, K.1
Wieder, T.2
Von Haefen, C.3
-
11
-
-
0036849351
-
P-glycoprotein inhibits caspase-8 activation but not formation of the death inducing signal complex (disc) following Fas ligation
-
Ruefli AA, Tainton KM, Darcy PK, Smyth MJ and Johnstone RW: P-glycoprotein inhibits caspase-8 activation but not formation of the death inducing signal complex (disc) following Fas ligation. Cell Death Differ 9: 1266-1272, 2002.
-
(2002)
Cell Death Differ
, vol.9
, pp. 1266-1272
-
-
Ruefli, A.A.1
Tainton, K.M.2
Darcy, P.K.3
Smyth, M.J.4
Johnstone, R.W.5
-
12
-
-
0037427122
-
NF-kappaB transcription factor induces drug resistance through MDR1 expression in cancer cells
-
Bentires-Alj M, Barbu V, Fillet M, et al: NF-kappaB transcription factor induces drug resistance through MDR1 expression in cancer cells. Oncogene 22: 90-97, 2003.
-
(2003)
Oncogene
, vol.22
, pp. 90-97
-
-
Bentires-Alj, M.1
Barbu, V.2
Fillet, M.3
-
13
-
-
28544451205
-
Control of multidrug resistance gene mdr1 and cancer resistance to chemotherapy by the longevity gene sirt1
-
Chu F, Chou PM, Zheng X, Mirkin BL and Rebbaa A: Control of multidrug resistance gene mdr1 and cancer resistance to chemotherapy by the longevity gene sirt1. Cancer Res 65: 10183-10187, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 10183-10187
-
-
Chu, F.1
Chou, P.M.2
Zheng, X.3
Mirkin, B.L.4
Rebbaa, A.5
-
14
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
Klionsky DJ and Emr SD: Autophagy as a regulated pathway of cellular degradation. Science 290: 1717-1721, 2000.
-
(2000)
Science
, vol.290
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
15
-
-
1842583789
-
Development by self-digestion: Molecular mechanisms and biological functions of autophagy
-
Levine B and Klionsky DJ: Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell 6: 463-477, 2004.
-
(2004)
Dev Cell
, vol.6
, pp. 463-477
-
-
Levine, B.1
Klionsky, D.J.2
-
16
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine B and Kroemer G: Autophagy in the pathogenesis of disease. Cell 132: 27-42, 2008.
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
17
-
-
9144240441
-
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
-
Qu X, Yu J, Bhagat G, et al: Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest 112: 1809-1820, 2003.
-
(2003)
J Clin Invest
, vol.112
, pp. 1809-1820
-
-
Qu, X.1
Yu, J.2
Bhagat, G.3
-
18
-
-
34147193472
-
Cell biology: Autophagy and cancer
-
Levine B: Cell biology: autophagy and cancer. Nature 446: 745-747, 2007.
-
(2007)
Nature
, vol.446
, pp. 745-747
-
-
Levine, B.1
-
19
-
-
79955377420
-
Autophagy-deficient mice develop multiple liver tumors
-
Takamura A, Komatsu M, Hara T, et al: Autophagy-deficient mice develop multiple liver tumors. Genes Dev 25: 795-800, 2011.
-
(2011)
Genes Dev
, vol.25
, pp. 795-800
-
-
Takamura, A.1
Komatsu, M.2
Hara, T.3
-
20
-
-
50349098812
-
Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells
-
Han J, Hou W, Goldstein LA, et al: Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells. J Biol Chem 283: 19665-19677, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 19665-19677
-
-
Han, J.1
Hou, W.2
Goldstein, L.A.3
-
21
-
-
33847008972
-
DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells
-
Katayama M, Kawaguchi T, Berger MS and Pieper RO: DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells. Cell Death Differ 14: 548-558, 2007.
-
(2007)
Cell Death Differ
, vol.14
, pp. 548-558
-
-
Katayama, M.1
Kawaguchi, T.2
Berger, M.S.3
Pieper, R.O.4
-
22
-
-
77955038334
-
The epidermal growth factor receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1alpha and Bcl-2 and activating the beclin 1/hVps34 complex
-
Li X and Fan Z: The epidermal growth factor receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1alpha and Bcl-2 and activating the beclin 1/hVps34 complex. Cancer Res 70: 5942-5952, 2010.
-
(2010)
Cancer Res
, vol.70
, pp. 5942-5952
-
-
Li, X.1
Fan, Z.2
-
23
-
-
33845459165
-
Autophagy is activated for cell survival after endoplasmic reticulum stress
-
Ogata M, Hino S, Saito A, et al: Autophagy is activated for cell survival after endoplasmic reticulum stress. Mol Cell Biol 26: 9220-9231, 2006.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 9220-9231
-
-
Ogata, M.1
Hino, S.2
Saito, A.3
-
24
-
-
79956147268
-
Overcoming multidrug resistance in human lung cancer with novel benzo[α] quinolizin-4-ones
-
Kanintronkul Y, Worayuthakarn R, Thasana N, et al: Overcoming multidrug resistance in human lung cancer with novel benzo[α] quinolizin-4-ones. Anticancer Res 31: 921-927, 2011.
-
(2011)
Anticancer Res
, vol.31
, pp. 921-927
-
-
Kanintronkul, Y.1
Worayuthakarn, R.2
Thasana, N.3
-
25
-
-
33646079159
-
Feroniellins A-C, novel cytotoxic furanocoumarins with highly oxygenated C10 moieties from Feroniella lucida
-
Phuwapraisirisan P, Surapinit S, Sombund S, Siripong P and Tip-pyang S: Feroniellins A-C, novel cytotoxic furanocoumarins with highly oxygenated C10 moieties from Feroniella lucida. Tetrahedron Lett 47: 3685-3688, 2006.
-
(2006)
Tetrahedron Lett
, vol.47
, pp. 3685-3688
-
-
Phuwapraisirisan, P.1
Surapinit, S.2
Sombund, S.3
Siripong, P.4
Tip-pyang, S.5
-
26
-
-
84868642028
-
Studies of the in vitro cytotoxic, antioxidant, lipase inhibitory and antimicrobial activities of selected Thai medicinal plants
-
Kaewpiboon C, Lirdprapamongkol K, Srisomsap C, et al: Studies of the in vitro cytotoxic, antioxidant, lipase inhibitory and antimicrobial activities of selected Thai medicinal plants. BMC Complement Altern Med 12: 217, 2012.
-
(2012)
BMC Complement Altern Med
, vol.12
, pp. 217
-
-
Kaewpiboon, C.1
Lirdprapamongkol, K.2
Srisomsap, C.3
-
27
-
-
84862778684
-
SIRT1 overexpression decreases cisplatin-induced acetylation of NF-kappaB p65 subunit and cytotoxicity in renal proximal tubule cells
-
Jung YJ, Lee JE, Lee AS, et al: SIRT1 overexpression decreases cisplatin-induced acetylation of NF-kappaB p65 subunit and cytotoxicity in renal proximal tubule cells. Biochem Biophys Res Commun 419: 206-210, 2012.
-
(2012)
Biochem Biophys Res Commun
, vol.419
, pp. 206-210
-
-
Jung, Y.J.1
Lee, J.E.2
Lee, A.S.3
-
28
-
-
25844443754
-
Breast cancer resistance protein: Molecular target for anticancer drug resistance and pharmacokinetics/pharmacodynamics
-
Sugimoto Y, Tsukahara S, Ishikawa E and Mitsuhashi J: Breast cancer resistance protein: molecular target for anticancer drug resistance and pharmacokinetics/pharmacodynamics. Cancer Sci 96: 457-465, 2005.
-
(2005)
Cancer Sci
, vol.96
, pp. 457-465
-
-
Sugimoto, Y.1
Tsukahara, S.2
Ishikawa, E.3
Mitsuhashi, J.4
-
29
-
-
0034895918
-
Multidrug resistance proteins MRP3, MRP1, and MRP2 in lung cancer: Correlation of protein levels with drug response and messenger RNA levels
-
Young LC, Campling BG, Cole SPC, Deeley RG and Gerlach JH: Multidrug resistance proteins MRP3, MRP1, and MRP2 in lung cancer: correlation of protein levels with drug response and messenger RNA levels. Clin Cancer Res 7: 1798-1804, 2001.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1798-1804
-
-
Young, L.C.1
Campling, B.G.2
Cole, S.P.C.3
Deeley, R.G.4
Gerlach, J.H.5
-
30
-
-
79551489371
-
Metformin inhibits P-glycoprotein expression via the NF-kappaB pathway and CRE transcriptional activity through AMPK activation
-
Kim HG, Hien TT, Han EH, et al: Metformin inhibits P-glycoprotein expression via the NF-kappaB pathway and CRE transcriptional activity through AMPK activation. Br J Pharmacol 162: 1096-1108, 2011.
-
(2011)
Br J Pharmacol
, vol.162
, pp. 1096-1108
-
-
Kim, H.G.1
Hien, T.T.2
Han, E.H.3
-
31
-
-
84865192351
-
Clitocine reversal of P-glycoprotein associated multi-drug resistance through downregulation of transcription factor NF-kappaB in R-HepG2 cell line
-
Sun J, Yeung CA, Co NN, et al: Clitocine reversal of P-glycoprotein associated multi-drug resistance through downregulation of transcription factor NF-kappaB in R-HepG2 cell line. PLoS One 7: e40720, 2012.
-
(2012)
PLoS One
, vol.7
-
-
Sun, J.1
Yeung, C.A.2
Co, N.N.3
-
32
-
-
79956224883
-
Targeting autophagy during cancer therapy to improve clinical outcomes
-
Levy JM and Thorburn A: Targeting autophagy during cancer therapy to improve clinical outcomes. Pharmacol Ther 131: 130-141, 2011.
-
(2011)
Pharmacol Ther
, vol.131
, pp. 130-141
-
-
Levy, J.M.1
Thorburn, A.2
-
34
-
-
77949595310
-
Autophagic and apoptotic mechanisms of curcumin-induced death in K562 cells
-
Jia YL, Li J, Qin ZH and Liang ZQ: Autophagic and apoptotic mechanisms of curcumin-induced death in K562 cells. J Asian Nat Prod Res 11: 918-928, 2009.
-
(2009)
J Asian Nat Prod Res
, vol.11
, pp. 918-928
-
-
Jia, Y.L.1
Li, J.2
Qin, Z.H.3
Liang, Z.Q.4
-
35
-
-
84872190720
-
Antitumor effects of rapamycin in pancreatic cancer cells by inducing apoptosis and autophagy
-
Dai ZJ, Gao J, Ma XB, et al: Antitumor effects of rapamycin in pancreatic cancer cells by inducing apoptosis and autophagy. Int J Mol Sci 14: 273-285, 2012.
-
(2012)
Int J Mol Sci
, vol.14
, pp. 273-285
-
-
Dai, Z.J.1
Gao, J.2
Ma, X.B.3
-
37
-
-
77954633764
-
Molecular mechanism of suppression of MDR1 by puerarin from Pueraria lobata via NF-kappaB pathway and cAMP-responsive element transcriptional activity-dependent up-regulation of AMP-activated protein kinase in breast cancer MCF-7/adr cells
-
Hien TT, Kim HG, Han EH, Kang KW and Jeong HG: Molecular mechanism of suppression of MDR1 by puerarin from Pueraria lobata via NF-kappaB pathway and cAMP-responsive element transcriptional activity-dependent up-regulation of AMP-activated protein kinase in breast cancer MCF-7/adr cells. Mol Nutr Food Res 54: 918-928, 2010.
-
(2010)
Mol Nutr Food Res
, vol.54
, pp. 918-928
-
-
Hien, T.T.1
Kim, H.G.2
Han, E.H.3
Kang, K.W.4
Jeong, H.G.5
-
38
-
-
84876417062
-
Reversal of P-glycoprotein-mediated multidrug resistance is induced by mollugin in MCF-7/adriamycin cells
-
Tran TP, Kim HG, Choi JH, Na MK and Jeong HG: Reversal of P-glycoprotein-mediated multidrug resistance is induced by mollugin in MCF-7/adriamycin cells. Phytomedicine 20: 622-631, 2013.
-
(2013)
Phytomedicine
, vol.20
, pp. 622-631
-
-
Tran, T.P.1
Kim, H.G.2
Choi, J.H.3
Na, M.K.4
Jeong, H.G.5
-
39
-
-
27644521173
-
Antibacterial and antioxidant activity of Sutherlandia frutescens (Fabaceae), a reputed anti-HIV/AIDS phytomedicine
-
Katerere DR and Eloff JN: Antibacterial and antioxidant activity of Sutherlandia frutescens (Fabaceae), a reputed anti-HIV/AIDS phytomedicine. Phytother Res 19: 779-781, 2005.
-
(2005)
Phytother Res
, vol.19
, pp. 779-781
-
-
Katerere, D.R.1
Eloff, J.N.2
-
40
-
-
84861813696
-
Interference of Frizzled 1 (FZD1) reverses multidrug resistance in breast cancer cells through the Wnt/beta-catenin pathway
-
Zhang H, Zhang X, Wu X, et al: Interference of Frizzled 1 (FZD1) reverses multidrug resistance in breast cancer cells through the Wnt/beta-catenin pathway. Cancer Lett 323: 106-113, 2012.
-
(2012)
Cancer Lett
, vol.323
, pp. 106-113
-
-
Zhang, H.1
Zhang, X.2
Wu, X.3
-
41
-
-
84857181300
-
Activating transcription factor 4 confers a multidrug resistance phenotype to gastric cancer cells through transactivation of SIRT1 expression
-
Zhu H, Xia L, Zhang Y, et al: Activating transcription factor 4 confers a multidrug resistance phenotype to gastric cancer cells through transactivation of SIRT1 expression. PLoS One 7: e31431, 2012.
-
(2012)
PLoS One
, vol.7
-
-
Zhu, H.1
Xia, L.2
Zhang, Y.3
-
42
-
-
84856748733
-
Cell death by autophagy: Facts and apparent artefacts
-
Denton D, Nicolson S and Kumar S: Cell death by autophagy: facts and apparent artefacts. Cell Death Differ 19: 87-95, 2012.
-
(2012)
Cell Death Differ
, vol.19
, pp. 87-95
-
-
Denton, D.1
Nicolson, S.2
Kumar, S.3
-
43
-
-
79961194820
-
Autophagy impairment induces premature senescence in primary human fibroblasts
-
Kang HT, Lee KB, Kim SY, Choi HR and Park SC: Autophagy impairment induces premature senescence in primary human fibroblasts. PLoS One 6: e23367, 2011.
-
(2011)
PLoS One
, vol.6
-
-
Kang, H.T.1
Lee, K.B.2
Kim, S.Y.3
Choi, H.R.4
Park, S.C.5
-
44
-
-
62449110463
-
Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling
-
Tal MC, Sasai M, Lee HK, Yordy B, Shadel GS and Iwasaki A: Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling. Proc Natl Acad Sci USA 106: 2770-2775, 2009.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2770-2775
-
-
Tal, M.C.1
Sasai, M.2
Lee, H.K.3
Yordy, B.4
Shadel, G.S.5
Iwasaki, A.6
-
45
-
-
84878992314
-
Autophagy inhibition sensitizes colon cancer cells to antiangiogenic and cytotoxic therapy
-
Selvakumaran M, Amaravadi RK, Vasilevskaya IA and O'Dwyer PJ: Autophagy inhibition sensitizes colon cancer cells to antiangiogenic and cytotoxic therapy. Clin Cancer Res 19: 2995-3007, 2013.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 2995-3007
-
-
Selvakumaran, M.1
Amaravadi, R.K.2
Vasilevskaya, I.A.3
O'Dwyer, P.J.4
-
46
-
-
84880303592
-
Autophagy inhibition induces enhanced proapoptotic effects of ZD6474 in glioblastoma
-
Shen J, Zheng H, Ruan J, et al: Autophagy inhibition induces enhanced proapoptotic effects of ZD6474 in glioblastoma. Br J Cancer 109: 164-171, 2013.
-
(2013)
Br J Cancer
, vol.109
, pp. 164-171
-
-
Shen, J.1
Zheng, H.2
Ruan, J.3
-
47
-
-
77957367974
-
Inhibition of autophagy enhances anticancer effects of atorvastatin in digestive malignancies
-
Yang PM, Liu YL, Lin YC, Shun CT, Wu MS and Chen CC: Inhibition of autophagy enhances anticancer effects of atorvastatin in digestive malignancies. Cancer Res 70: 7699-7709, 2010.
-
(2010)
Cancer Res
, vol.70
, pp. 7699-7709
-
-
Yang, P.M.1
Liu, Y.L.2
Lin, Y.C.3
Shun, C.T.4
Wu, M.S.5
Chen, C.C.6
-
48
-
-
77953383616
-
Autophagy blockade sensitizes prostate cancer cells towards Src family kinase inhibitors
-
Wu Z, Chang PC, Yang JC, et al: Autophagy blockade sensitizes prostate cancer cells towards Src family kinase inhibitors. Genes Cancer 1: 40-49, 2010.
-
(2010)
Genes Cancer
, vol.1
, pp. 40-49
-
-
Wu, Z.1
Chang, P.C.2
Yang, J.C.3
-
49
-
-
84878186041
-
The mTOR inhibitor RAD001 potentiates autophagic cell death induced by temozolomide in a glioblastoma cell line
-
Josset E, Burckel H, Noel G and Bischoff P: The mTOR inhibitor RAD001 potentiates autophagic cell death induced by temozolomide in a glioblastoma cell line. Anticancer Res 33: 1845-1851, 2013.
-
(2013)
Anticancer Res
, vol.33
, pp. 1845-1851
-
-
Josset, E.1
Burckel, H.2
Noel, G.3
Bischoff, P.4
-
50
-
-
17144427728
-
Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors
-
Takeuchi H, Kondo Y, Fujiwara K, et al: Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors. Cancer Res 65: 3336-3346, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 3336-3346
-
-
Takeuchi, H.1
Kondo, Y.2
Fujiwara, K.3
|