Detection of in vivo enzyme activity with CatalyCEST MRI

Magnetic Resonance in Medicine

Volumn 71, Issue 3, 2014, Pages 1221-1230

  Yoo, Byunghee ^a   Sheth, Vipul R ^b   Howison, Christine M ^c   Douglas, Matthew J K ^d   Pineda, Carlos T ^d   Maine, Erin A ^d   Baker, Amanda F ^d,e   Pagel, Mark D ^d,f,g  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Case Western Reserve University   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

^d UNIVERSITY OF ARIZONA   (United States)

^e UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^f University of Arizona   (United States)

^g University of Arizona   (United States)

Author keywords

CEST MRI; contrast agents; enzyme activity; molecular imaging

Indexed keywords

CHEMICAL DETECTION; ENZYME ACTIVITY; IMAGE SEGMENTATION; MAGNETIC RESONANCE IMAGING; PHARMACOKINETICS; TUMORS;

CEST MRIS; CHEMICAL EXCHANGE SATURATION TRANSFER; CONTRAST AGENT; INTRAVENOUS INJECTIONS; LORENTZIAN LINE SHAPE; REGION OF INTEREST; SPECTROSCOPIC IMAGES; UROKINASE PLASMINOGEN;

MOLECULAR IMAGING;

CHEMICAL EXCHANGE SATURATION TRANSFER NUCLEAR AGENT; CONTRAST MEDIUM; UNCLASSIFIED DRUG; UROKINASE; 1,4,7,10-TETRAAZACYCLODODECANE- 1,4,7,10-TETRAACETIC ACID; RADIOPHARMACEUTICAL AGENT; SINGLE HETEROCYCLIC RINGS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CATALYSIS; CHEMICAL EXCHANGE SATURATION TRANSFER NUCLEAR MAGNETIC RESONANCE IMAGING; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME KINETICS; FEASIBILITY STUDY; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MAGNETIC FIELD; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PANCREAS TUMOR; STEADY STATE; SYNTHESIS; ANIMAL; ENZYME ACTIVATION; ENZYMOLOGY; METABOLISM; MOLECULAR IMAGING; PATHOLOGY; PROCEDURES; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; TUMOR CELL LINE;

ANIMALS; CATALYSIS; CELL LINE, TUMOR; ENZYME ACTIVATION; FEASIBILITY STUDIES; HETEROCYCLIC COMPOUNDS, 1-RING; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MOLECULAR IMAGING; PANCREATIC NEOPLASMS; RADIOPHARMACEUTICALS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 84894421739     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.24763     Document Type: Article

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