Sizing up large protein complexes by electrospray ionisation-based electrophoretic mobility and native mass spectrometry: Morphology selective binding of Fabs to hepatitis B virus capsids

Analytical and Bioanalytical Chemistry

Volumn 406, Issue 5, 2014, Pages 1437-1446

  Bereszczak, Jessica Z ^a   Havlik, Marlene ^b   Weiss, Victor U ^b   Marchetti Deschmann, Martina ^b   Van Duijn, Esther ^d   Watts, Norman R ^c   Wingfield, Paul T ^c   Allmaier, Guenter ^b   Steven, Alasdair C ^c   Heck, Albert J R ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b VIENNA UNIVERSITY OF TECHNOLOGY   (Austria)

^c NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^d TNO   (Netherlands)

Author keywords

GEMMA; Hepatitis B; Immune complex; Native MS; Quasi equivalence; Virus antibody complexes

Indexed keywords

IMMUNOGLOBULIN F(AB) FRAGMENT; VIRUS ANTIGEN;

ANTIGEN ANTIBODY COMPLEX; BINDING SITE; CHEMISTRY; CONFERENCE PAPER; ELECTROSPRAY MASS SPECTROMETRY; HEPATITIS B VIRUS; HUMAN; IMMUNOLOGY; MASS SPECTROMETRY; METHODOLOGY; PROTEIN BINDING; PROTEIN DOMAIN; VIRUS CAPSID;

ANTIGEN-ANTIBODY COMPLEX; ANTIGENS, VIRAL; BINDING SITES; CAPSID; HEPATITIS B VIRUS; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; MASS SPECTROMETRY; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84894416052     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-013-7548-z     Document Type: Conference Paper

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