-
1
-
-
80555149812
-
Mycobacterial secretion systems ESX-1 and ESX-5 play distinct roles in host cell death and inflammasome activation
-
Abdallah, A. M., Bestebroer, J., Savage, N. D., de Punder, K., van Zon, M., Wilson, L., Korbee, C. J., van der Sar, A. M., Ottenhoff, T. H., van der Wel, N. N. et al. (2011). Mycobacterial secretion systems ESX-1 and ESX-5 play distinct roles in host cell death and inflammasome activation. J. Immunol. 187, 4744-4753.
-
(2011)
J. Immunol.
, vol.187
, pp. 4744-4753
-
-
Abdallah, A.M.1
Bestebroer, J.2
Savage, N.D.3
De Punder, K.4
Van Zon, M.5
Wilson, L.6
Korbee, C.J.7
Van Der Sar, A.M.8
Ottenhoff, T.H.9
Van Der Wel, N.N.10
-
2
-
-
79955031171
-
Aprabc: A Mycobacterium tuberculosis complex-specific locus that modulates pH-driven adaptation to the macrophage phagosome
-
Abramovitch, R. B., Rohde, K. H., Hsu, F. F. and Russell, D. G. (2011). aprABC: a Mycobacterium tuberculosis complex-specific locus that modulates pH-driven adaptation to the macrophage phagosome. Mol. Microbiol. 80, 678-694.
-
(2011)
Mol. Microbiol.
, vol.80
, pp. 678-694
-
-
Abramovitch, R.B.1
Rohde, K.H.2
Hsu, F.F.3
Russell, D.G.4
-
3
-
-
84860355561
-
Local immune responses in human tuberculosis: Learning from the site of infection
-
Brighenti, S. and Andersson, J. (2012). Local immune responses in human tuberculosis: learning from the site of infection. J. Infect. Dis. 205 Suppl., S316-S324.
-
(2012)
J. Infect. Dis
, vol.205 SUPPL.
-
-
Brighenti, S.1
Andersson, J.2
-
4
-
-
77954050777
-
Host-detrimental role of Esx-1-mediated inflammasome activation in mycobacterial infection
-
Carlsson, F., Kim, J., Dumitru, C., Barck, K. H., Carano, R. A., Sun, M., Diehl, L. and Brown, E. J. (2010). Host-detrimental role of Esx-1-mediated inflammasome activation in mycobacterial infection. PLoS Pathog. 6, e1000895.
-
(2010)
PLoS Pathog.
, vol.6
-
-
Carlsson, F.1
Kim, J.2
Dumitru, C.3
Barck, K.H.4
Carano, R.A.5
Sun, M.6
Diehl, L.7
Brown, E.J.8
-
5
-
-
0027928745
-
CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells
-
Cozens, A. L., Yezzi, M. J., Kunzelmann, K., Ohrui, T., Chin, L., Eng, K., Finkbeiner, W. E., Widdicombe, J. H. and Gruenert, D. C. (1994). CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells. Am. J. Respir. Cell Mol. Biol. 10, 38-47.
-
(1994)
Am. J. Respir. Cell Mol. Biol.
, vol.10
, pp. 38-47
-
-
Cozens, A.L.1
Yezzi, M.J.2
Kunzelmann, K.3
Ohrui, T.4
Chin, L.5
Eng, K.6
Finkbeiner, W.E.7
Widdicombe, J.H.8
Gruenert, D.C.9
-
6
-
-
58149083837
-
The role of the granuloma in expansion and dissemination of early tuberculous infection
-
Davis, J. M. and Ramakrishnan, L. (2009). The role of the granuloma in expansion and dissemination of early tuberculous infection. Cell 136, 37-49.
-
(2009)
Cell
, vol.136
, pp. 37-49
-
-
Davis, J.M.1
Ramakrishnan, L.2
-
7
-
-
67650655950
-
A novel in vitro multiple-stress dormancy model for Mycobacterium tuberculosis generates a lipid-loaded, drugtolerant, dormant pathogen
-
Deb, C., Lee, C. M., Dubey, V. S., Daniel, J., Abomoelak, B., Sirakova, T. D., Pawar, S., Rogers, L. and Kolattukudy, P. E. (2009). A novel in vitro multiple-stress dormancy model for Mycobacterium tuberculosis generates a lipid-loaded, drugtolerant, dormant pathogen. PLoS ONE 4, e6077.
-
(2009)
PLoS ONE
, vol.4
-
-
Deb, C.1
Lee, C.M.2
Dubey, V.S.3
Daniel, J.4
Abomoelak, B.5
Sirakova, T.D.6
Pawar, S.7
Rogers, L.8
Kolattukudy, P.E.9
-
8
-
-
33646793320
-
Development of a novel threedimensional in vitro model of oral Candida infection
-
Dongari-Bagtzoglou, A. and Kashleva, H. (2006). Development of a novel threedimensional in vitro model of oral Candida infection. Microb. Pathog. 40, 271-278.
-
(2006)
Microb. Pathog.
, vol.40
, pp. 271-278
-
-
Dongari-Bagtzoglou, A.1
Kashleva, H.2
-
9
-
-
79955111092
-
Macrophages and control of granulomatous inflammation in tuberculosis
-
Flynn, J. L., Chan, J. and Lin, P. L. (2011). Macrophages and control of granulomatous inflammation in tuberculosis. Mucosal Immunol. 4, 271-278.
-
(2011)
Mucosal Immunol.
, vol.4
, pp. 271-278
-
-
Flynn, J.L.1
Chan, J.2
Lin, P.L.3
-
10
-
-
40349106159
-
Control of M. Tuberculosis ESAT-6secretion and specific T cell recognition by PhoP
-
Frigui, W., Bottai, D., Majlessi, L., Monot, M., Josselin, E., Brodin, P., Garnier, T., Gicquel, B., Martin, C., Leclerc, C. et al. (2008). Control of M. tuberculosis ESAT-6secretion and specific T cell recognition by PhoP. PLoS Pathog. 4, e33.
-
(2008)
PLoS Pathog.
, vol.4
-
-
Frigui, W.1
Bottai, D.2
Majlessi, L.3
Monot, M.4
Josselin, E.5
Brodin, P.6
Garnier, T.7
Gicquel, B.8
Martin, C.9
Leclerc, C.10
-
12
-
-
84863993689
-
ESX-1- mediated translocation to the cytosol controls virulence of mycobacteria
-
Houben, D., Demangel, C., van Ingen, J., Perez, J., Baldeón, L., Abdallah, A. M., Caleechurn, L., Bottai, D., van Zon, M., de Punder, K. et al. (2012). ESX-1- mediated translocation to the cytosol controls virulence of mycobacteria. Cell Microbiol. 14, 1287-1298.
-
(2012)
Cell Microbiol.
, vol.14
, pp. 1287-1298
-
-
Houben, D.1
Demangel, C.2
Van Ingen, J.3
Perez, J.4
Baldeón, L.5
Abdallah, A.M.6
Caleechurn, L.7
Bottai, D.8
Van Zon, M.9
De Punder, K.10
-
13
-
-
84872131454
-
Human granuloma in vitro model, for TB dormancy and resuscitation
-
Kapoor, N., Pawar, S., Sirakova, T. D., Deb, C., Warren, W. L. and Kolattukudy, P. E. (2013). Human granuloma in vitro model, for TB dormancy and resuscitation. PLoS ONE 8, e53657.
-
(2013)
PLoS ONE
, vol.8
-
-
Kapoor, N.1
Pawar, S.2
Sirakova, T.D.3
Deb, C.4
Warren, W.L.5
Kolattukudy, P.E.6
-
14
-
-
56949100513
-
Guinea pig model of Mycobacterium tuberculosis latent/dormant infection
-
Kashino, S. S., Napolitano, D. R., Skobe, Z. and Campos-Neto, A. (2008). Guinea pig model of Mycobacterium tuberculosis latent/dormant infection. Microbes Infect. 10, 1469-1476.
-
(2008)
Microbes Infect.
, vol.10
, pp. 1469-1476
-
-
Kashino, S.S.1
Napolitano, D.R.2
Skobe, Z.3
Campos-Neto, A.4
-
15
-
-
0027463178
-
BCG-induced protection in guinea pigs vaccinated and challenged via the respiratory route
-
Lagranderie, M., Ravisse, P., Marchal, G., Gheorghiu, M., Balasubramanian, V., Weigeshaus, E. H. and Smith, D. W. (1993). BCG-induced protection in guinea pigs vaccinated and challenged via the respiratory route. Tuber. Lung Dis. 74, 38-46.
-
(1993)
Tuber. Lung Dis.
, vol.74
, pp. 38-46
-
-
Lagranderie, M.1
Ravisse, P.2
Marchal, G.3
Gheorghiu, M.4
Balasubramanian, V.5
Weigeshaus, E.H.6
Smith, D.W.7
-
16
-
-
0037219942
-
Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guérin attenuation
-
Lewis, K. N., Liao, R., Guinn, K. M., Hickey, M. J., Smith, S., Behr, M. A. and Sherman, D. R. (2003). Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guérin attenuation. J. Infect. Dis. 187, 117-123.
-
(2003)
J. Infect. Dis.
, vol.187
, pp. 117-123
-
-
Lewis, K.N.1
Liao, R.2
Guinn, K.M.3
Hickey, M.J.4
Smith, S.5
Behr, M.A.6
Sherman, D.R.7
-
17
-
-
75749099727
-
Tumor necrosis factor neutralization results in disseminated disease in acute and latent Mycobacterium tuberculosis infection with normal granuloma structure in a cynomolgus macaque model
-
Lin, P. L., Myers, A., Smith, L., Bigbee, C., Bigbee, M., Fuhrman, C., Grieser, H., Chiosea, I., Voitenek, N. N., Capuano, S. V. et al. (2010). Tumor necrosis factor neutralization results in disseminated disease in acute and latent Mycobacterium tuberculosis infection with normal granuloma structure in a cynomolgus macaque model. Arthritis Rheum. 62, 340-350.
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 340-350
-
-
Lin, P.L.1
Myers, A.2
Smith, L.3
Bigbee, C.4
Bigbee, M.5
Fuhrman, C.6
Grieser, H.7
Chiosea, I.8
Voitenek, N.N.9
Capuano, S.V.10
-
18
-
-
84871036375
-
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010
-
Lozano, R., Naghavi, M., Foreman, K., Lim, S., Shibuya, K., Aboyans, V., Abraham, J., Adair, T., Aggarwal, R., Ahn, S. Y. et al. (2012). Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 380, 2095-2128.
-
(2012)
Lancet
, vol.380
, pp. 2095-2128
-
-
Lozano, R.1
Naghavi, M.2
Foreman, K.3
Lim, S.4
Shibuya, K.5
Aboyans, V.6
Abraham, J.7
Adair, T.8
Aggarwal, R.9
Ahn, S.Y.10
-
19
-
-
84855332758
-
Dendritic cell functional properties in a three-dimensional tissue model of human lung mucosa
-
Nguyen Hoang, A. T., Chen, P., Juarez, J., Sachamitr, P., Billing, B., Bosnjak, L., Dahlén, B., Coles, M. and Svensson, M. (2012). Dendritic cell functional properties in a three-dimensional tissue model of human lung mucosa. Am. J. Physiol. 302, L226-L237.
-
(2012)
Am. J. Physiol.
, vol.302
-
-
Nguyen Hoang, A.T.1
Chen, P.2
Juarez, J.3
Sachamitr, P.4
Billing, B.5
Bosnjak, L.6
Dahlén, B.7
Coles, M.8
Svensson, M.9
-
20
-
-
1842861893
-
An in vitro dual model of mycobacterial granulomas to investigate the molecular interactions between mycobacteria and human host cells
-
Puissegur, M. P., Botanch, C., Duteyrat, J. L., Delsol, G., Caratero, C. and Altare, F. (2004). An in vitro dual model of mycobacterial granulomas to investigate the molecular interactions between mycobacteria and human host cells. Cell. Microbiol. 6, 423-433.
-
(2004)
Cell. Microbiol.
, vol.6
, pp. 423-433
-
-
Puissegur, M.P.1
Botanch, C.2
Duteyrat, J.L.3
Delsol, G.4
Caratero, C.5
Altare, F.6
-
21
-
-
0036437048
-
Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti
-
Pym, A. S., Brodin, P., Brosch, R., Huerre, M. and Cole, S. T. (2002). Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti. Mol. Microbiol. 46, 709-717.
-
(2002)
Mol. Microbiol.
, vol.46
, pp. 709-717
-
-
Pym, A.S.1
Brodin, P.2
Brosch, R.3
Huerre, M.4
Cole, S.T.5
-
22
-
-
67049142962
-
Compartmentalization of immune responses in human tuberculosis: Few CD8+effector T cells but elevated levels of FoxP3+ regulatory t cells in the granulomatous lesions
-
Rahman, S., Gudetta, B., Fink, J., Granath, A., Ashenafi, S., Aseffa, A., Derbew, M., Svensson, M., Andersson, J. and Brighenti, S. G. (2009). Compartmentalization of immune responses in human tuberculosis: few CD8+effector T cells but elevated levels of FoxP3+ regulatory t cells in the granulomatous lesions. Am. J. Pathol. 174, 2211-2224.
-
(2009)
Am. J. Pathol.
, vol.174
, pp. 2211-2224
-
-
Rahman, S.1
Gudetta, B.2
Fink, J.3
Granath, A.4
Ashenafi, S.5
Aseffa, A.6
Derbew, M.7
Svensson, M.8
Andersson, J.9
Brighenti, S.G.10
-
23
-
-
84874684544
-
Prime-boost vaccination with rBCG/rAd35 enhances CD8+ cytolytic T-cell responses in lesions from Mycobacterium tuberculosis-infected primates
-
Rahman, S., Magalhaes, I., Rahman, J., Ahmed, R. K., Sizemore, D. R., Scanga, C. A., Weichold, F., Verreck, F., Kondova, I., Sadoff, J. et al. (2012). Prime-boost vaccination with rBCG/rAd35 enhances CD8+ cytolytic T-cell responses in lesions from Mycobacterium tuberculosis-infected primates. Mol. Med. 18, 647-658.
-
(2012)
Mol. Med.
, vol.18
, pp. 647-658
-
-
Rahman, S.1
Magalhaes, I.2
Rahman, J.3
Ahmed, R.K.4
Sizemore, D.R.5
Scanga, C.A.6
Weichold, F.7
Verreck, F.8
Kondova, I.9
Sadoff, J.10
-
24
-
-
69049108875
-
Foamy macrophages and the progression of the human tuberculosis granuloma
-
Russell, D. G., Cardona, P. J., Kim, M. J., Allain, S. and Altare, F. (2009). Foamy macrophages and the progression of the human tuberculosis granuloma. Nat. Immunol. 10, 943-948.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 943-948
-
-
Russell, D.G.1
Cardona, P.J.2
Kim, M.J.3
Allain, S.4
Altare, F.5
-
25
-
-
33947172058
-
Life and death in the granuloma: Immunopathology of tuberculosis
-
Saunders, B. M. and Britton, W. J. (2007). Life and death in the granuloma: immunopathology of tuberculosis. Immunol. Cell Biol. 85, 103-111.
-
(2007)
Immunol. Cell Biol.
, vol.85
, pp. 103-111
-
-
Saunders, B.M.1
Britton, W.J.2
-
26
-
-
0037062934
-
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
-
Scaffidi, P., Misteli, T. and Bianchi, M. E. (2002). Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 418, 191-195.
-
(2002)
Nature
, vol.418
, pp. 191-195
-
-
Scaffidi, P.1
Misteli, T.2
Bianchi, M.E.3
-
27
-
-
79954611256
-
Experimental tuberculosis in the Wistar rat: A model for protective immunity and control of infection
-
Singhal, A., Aliouat, M., Hervé, M., Mathys, V., Kiass, M., Creusy, C., Delaire, B., Tsenova, L., Fleurisse, L., Bertout, J. et al. (2011). Experimental tuberculosis in the Wistar rat: a model for protective immunity and control of infection. PLoS ONE 6, e18632.
-
(2011)
PLoS ONE
, vol.6
-
-
Singhal, A.1
Aliouat, M.2
Hervé, M.3
Mathys, V.4
Kiass, M.5
Creusy, C.6
Delaire, B.7
Tsenova, L.8
Fleurisse, L.9
Bertout, J.10
-
28
-
-
79959658128
-
Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component
-
Stoop, E. J., Schipper, T., Huber, S. K., Nezhinsky, A. E., Verbeek, F. J., Gurcha, S. S., Besra, G. S., Vandenbroucke-Grauls, C. M., Bitter, W. and van der Sar, A. M. (2011). Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component. Dis. Model. Mech. 4, 526-536.
-
(2011)
Dis. Model. Mech.
, vol.4
, pp. 526-536
-
-
Stoop, E.J.1
Schipper, T.2
Huber, S.K.3
Nezhinsky, A.E.4
Verbeek, F.J.5
Gurcha, S.S.6
Besra, G.S.7
Vandenbroucke-Grauls, C.M.8
Bitter, W.9
Van Der Sar, A.M.10
-
29
-
-
80053452071
-
Phosphodiesterase-4 inhibition alters gene expression and improves isoniazid-mediated clearance of Mycobacterium tuberculosis in rabbit lungs
-
Subbian, S., Tsenova, L., O'Brien, P., Yang, G., Koo, M. S., Peixoto, B., Fallows, D., Dartois, V., Muller, G. and Kaplan, G. (2011). Phosphodiesterase-4 inhibition alters gene expression and improves isoniazid-mediated clearance of Mycobacterium tuberculosis in rabbit lungs. PLoS Pathog. 7, e1002262.
-
(2011)
PLoS Pathog.
, vol.7
-
-
Subbian, S.1
Tsenova, L.2
O'brien, P.3
Yang, G.4
Koo, M.S.5
Peixoto, B.6
Fallows, D.7
Dartois, V.8
Muller, G.9
Kaplan, G.10
-
30
-
-
5044239313
-
Human tuberculous granulomas induce peripheral lymphoid follicle-like structures to orchestrate local host defence in the lung
-
Ulrichs, T., Kosmiadi, G. A., Trusov, V., Jörg, S., Pradl, L., Titukhina, M., Mishenko, V., Gushina, N. and Kaufmann, S. H. (2004). Human tuberculous granulomas induce peripheral lymphoid follicle-like structures to orchestrate local host defence in the lung. J. Pathol. 204, 217-228.
-
(2004)
J. Pathol.
, vol.204
, pp. 217-228
-
-
Ulrichs, T.1
Kosmiadi, G.A.2
Trusov, V.3
Jörg, S.4
Pradl, L.5
Titukhina, M.6
Mishenko, V.7
Gushina, N.8
Kaufmann, S.H.9
-
31
-
-
34547642553
-
Mycobacterium tuberculosis nuoG is a virulence gene that inhibits apoptosis of infected host cells
-
Velmurugan, K., Chen, B., Miller, J. L., Azogue, S., Gurses, S., Hsu, T., Glickman, M., Jacobs, W. R., Jr, Porcelli, S. A. and Briken, V. (2007). Mycobacterium tuberculosis nuoG is a virulence gene that inhibits apoptosis of infected host cells. PLoS Pathog. 3, e110.
-
(2007)
PLoS Pathog.
, vol.3
-
-
Velmurugan, K.1
Chen, B.2
Miller, J.L.3
Azogue, S.4
Gurses, S.5
Hsu, T.6
Glickman, M.7
Jacobs Jr., W.R.8
Porcelli, S.A.9
Briken, V.10
-
32
-
-
14044254749
-
Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant
-
Volkman, H. E., Clay, H., Beery, D., Chang, J. C., Sherman, D. R. and Ramakrishnan, L. (2004). Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant. PLoS Biol. 2, e367.
-
(2004)
PLoS Biol.
, vol.2
-
-
Volkman, H.E.1
Clay, H.2
Beery, D.3
Chang, J.C.4
Sherman, D.R.5
Ramakrishnan, L.6
-
33
-
-
75649141266
-
Tuberculous granuloma induction via interaction of a bacterial secreted protein with host epithelium
-
Volkman, H. E., Pozos, T. C., Zheng, J., Davis, J. M., Rawls, J. F. and Ramakrishnan, L. (2010). Tuberculous granuloma induction via interaction of a bacterial secreted protein with host epithelium. Science 327, 466-469.
-
(2010)
Science
, vol.327
, pp. 466-469
-
-
Volkman, H.E.1
Pozos, T.C.2
Zheng, J.3
Davis, J.M.4
Rawls, J.F.5
Ramakrishnan, L.6
-
34
-
-
79957554114
-
Human macrophages infected with a high burden of ESAT-6-expressing M. Tuberculosis undergo caspase- 1- and cathepsin B-independent necrosis
-
Welin, A., Eklund, D., Stendahl, O. and Lerm, M. (2011a). Human macrophages infected with a high burden of ESAT-6-expressing M. tuberculosis undergo caspase- 1- and cathepsin B-independent necrosis. PLoS ONE 6, e20302.
-
(2011)
PLoS ONE
, vol.6
-
-
Welin, A.1
Eklund, D.2
Stendahl, O.3
Lerm, M.4
-
35
-
-
80052050200
-
Importance of phagosomal functionality for growth restriction of Mycobacterium tuberculosis in primary human macrophages
-
Welin, A., Raffetseder, J., Eklund, D., Stendahl, O. and Lerm, M. (2011b). Importance of phagosomal functionality for growth restriction of Mycobacterium tuberculosis in primary human macrophages. J. Innate Immun. 3, 508-518.
-
(2011)
J. Innate Immun.
, vol.3
, pp. 508-518
-
-
Welin, A.1
Raffetseder, J.2
Eklund, D.3
Stendahl, O.4
Lerm, M.5
|