-
1
-
-
78751656754
-
Role of Rab GTPases in membrane traffic and cell physiology
-
Hutagalung AH, Novick PJ (2011) Role of Rab GTPases in membrane traffic and cell physiology. Physiol Rev 91(1):119-149.
-
(2011)
Physiol Rev
, vol.91
, Issue.1
, pp. 119-149
-
-
Hutagalung, A.H.1
Novick, P.J.2
-
2
-
-
68049105101
-
Rab GTPases as coordinators of vesicle traffic
-
Stenmark H (2009) Rab GTPases as coordinators of vesicle traffic. Nat Rev Mol Cell Biol 10(8):513-525.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, Issue.8
, pp. 513-525
-
-
Stenmark, H.1
-
3
-
-
0035798385
-
Evolution of the Rab family of small GTP-binding proteins
-
Pereira-Leal JB, Seabra MC (2001) Evolution of the Rab family of small GTP-binding proteins. J Mol Biol 313(4):889-901.
-
(2001)
J Mol Biol
, vol.313
, Issue.4
, pp. 889-901
-
-
Pereira-Leal, J.B.1
Seabra, M.C.2
-
4
-
-
0029966304
-
Protein prenyltransferases
-
Casey PJ, Seabra MC (1996) Protein prenyltransferases. J Biol Chem 271(10):5289-5292.
-
(1996)
J Biol Chem
, vol.271
, Issue.10
, pp. 5289-5292
-
-
Casey, P.J.1
Seabra, M.C.2
-
5
-
-
0037291870
-
Structure of Rab escort protein-1 in complex with Rab geranylgeranyltransferase
-
Pylypenko O, et al. (2003) Structure of Rab escort protein-1 in complex with Rab geranylgeranyltransferase. Mol Cell 11(2):483-494.
-
(2003)
Mol Cell
, vol.11
, Issue.2
, pp. 483-494
-
-
Pylypenko, O.1
-
6
-
-
2942575037
-
Structure of the Rab7:REP-1 complex: Insights into the mechanism of Rab prenylation and choroideremia disease
-
Rak A, et al. (2004) Structure of the Rab7:REP-1 complex: Insights into the mechanism of Rab prenylation and choroideremia disease. Cell 117(6):749-760.
-
(2004)
Cell
, vol.117
, Issue.6
, pp. 749-760
-
-
Rak, A.1
-
7
-
-
67649690942
-
Structure of the disordered C terminus of Rab7 GTPase induced by binding to the Rab geranylgeranyl transferase catalytic complex reveals the mechanism of Rab prenylation
-
Wu YW, Goody RS, Abagyan R, Alexandrov K (2009) Structure of the disordered C terminus of Rab7 GTPase induced by binding to the Rab geranylgeranyl transferase catalytic complex reveals the mechanism of Rab prenylation. J Biol Chem 284(19): 13185-13192.
-
(2009)
J Biol Chem
, vol.284
, Issue.19
, pp. 13185-13192
-
-
Wu, Y.W.1
Goody, R.S.2
Abagyan, R.3
Alexandrov, K.4
-
8
-
-
34547636357
-
Interaction analysis of prenylated Rab GTPase with Rab escort protein and GDP dissociation inhibitor explains the need for both regulators
-
Wu YW, Tan KT, Waldmann H, Goody RS, Alexandrov K (2007) Interaction analysis of prenylated Rab GTPase with Rab escort protein and GDP dissociation inhibitor explains the need for both regulators. Proc Natl Acad Sci USA 104(30):12294-12299.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.30
, pp. 12294-12299
-
-
Wu, Y.W.1
Tan, K.T.2
Waldmann, H.3
Goody, R.S.4
Alexandrov, K.5
-
9
-
-
0031023505
-
Identification of a GDI displacement factor that releases endosomal Rab GTPases from Rab-GDI
-
Dirac-Svejstrup AB, Sumizawa T, Pfeffer SR (1997) Identification of a GDI displacement factor that releases endosomal Rab GTPases from Rab-GDI. EMBO J 16(3):465-472.
-
(1997)
EMBO J
, vol.16
, Issue.3
, pp. 465-472
-
-
Dirac-Svejstrup, A.B.1
Sumizawa, T.2
Pfeffer, S.R.3
-
10
-
-
0242363237
-
Yip3 catalyses the dissociation of endosomal Rab-GDI complexes
-
Sivars U, Aivazian D, Pfeffer SR (2003) Yip3 catalyses the dissociation of endosomal Rab-GDI complexes. Nature 425(6960):856-859.
-
(2003)
Nature
, vol.425
, Issue.6960
, pp. 856-859
-
-
Sivars, U.1
Aivazian, D.2
Pfeffer, S.R.3
-
11
-
-
0025948794
-
Hypervariable C-terminal domain of rab proteins acts as a targeting signal
-
Chavrier P, et al. (1991) Hypervariable C-terminal domain of rab proteins acts as a targeting signal. Nature 353(6346):769-772.
-
(1991)
Nature
, vol.353
, Issue.6346
, pp. 769-772
-
-
Chavrier, P.1
-
12
-
-
33745280280
-
TIP47 is a key effector for Rab9 localization
-
Aivazian D, Serrano RL, Pfeffer S (2006) TIP47 is a key effector for Rab9 localization. J Cell Biol 173(6):917-926.
-
(2006)
J Cell Biol
, vol.173
, Issue.6
, pp. 917-926
-
-
Aivazian, D.1
Serrano, R.L.2
Pfeffer, S.3
-
13
-
-
13444292179
-
Multiple regions contribute to membrane targeting of Rab GTPases
-
Ali BR, Wasmeier C, Lamoreux L, Strom M, Seabra MC (2004) Multiple regions contribute to membrane targeting of Rab GTPases. J Cell Sci 117(Pt 26):6401-6412.
-
(2004)
J Cell Sci
, vol.117
, Issue.PART 26
, pp. 6401-6412
-
-
Ali, B.R.1
Wasmeier, C.2
Lamoreux, L.3
Strom, M.4
Seabra, M.C.5
-
14
-
-
0028144416
-
The effector domain of Rab6, plus a highly hydrophobic C terminus, is required for Golgi apparatus localization
-
Beranger F, Paterson H, Powers S, de Gunzburg J, Hancock JF (1994) The effector domain of Rab6, plus a highly hydrophobic C terminus, is required for Golgi apparatus localization. Mol Cell Biol 14(1):744-758.
-
(1994)
Mol Cell Biol
, vol.14
, Issue.1
, pp. 744-758
-
-
Beranger, F.1
Paterson, H.2
Powers, S.3
De Gunzburg, J.4
Hancock, J.F.5
-
15
-
-
77953809435
-
Membrane targeting mechanism of Rab GTPases elucidated by semisynthetic protein probes
-
Wu YW, et al. (2010) Membrane targeting mechanism of Rab GTPases elucidated by semisynthetic protein probes. Nat Chem Biol 6(7):534-540.
-
(2010)
Nat Chem Biol
, vol.6
, Issue.7
, pp. 534-540
-
-
Wu, Y.W.1
-
16
-
-
57749121492
-
Chemoselective ligation and modification strategies for peptides and proteins
-
Hackenberger CP, Schwarzer D (2008) Chemoselective ligation and modification strategies for peptides and proteins. Angew Chem Int Ed Engl 47(52):10030-10074.
-
(2008)
Angew Chem Int Ed Engl
, vol.47
, Issue.52
, pp. 10030-10074
-
-
Hackenberger, C.P.1
Schwarzer, D.2
-
17
-
-
77957758860
-
Biological applications of protein splicing
-
Vila-Perelló M, Muir TW (2010) Biological applications of protein splicing. Cell 143(2): 191-200.
-
(2010)
Cell
, vol.143
, Issue.2
, pp. 191-200
-
-
Vila-Perelló, M.1
Muir, T.W.2
-
18
-
-
80052077967
-
One-pot dual-labeling of a protein by two chemoselective reactions
-
Yi L, et al. (2011) One-pot dual-labeling of a protein by two chemoselective reactions. Angew Chem Int Ed Engl 50(36):8287-8290.
-
(2011)
Angew Chem Int Ed Engl
, vol.50
, Issue.36
, pp. 8287-8290
-
-
Yi, L.1
-
19
-
-
0034714098
-
The mammalian Rab family of small GTPases: Definition of family and subfamily sequence motifs suggests a mechanism for functional specificity in the Ras superfamily
-
Pereira-Leal JB, Seabra MC (2000) The mammalian Rab family of small GTPases: Definition of family and subfamily sequence motifs suggests a mechanism for functional specificity in the Ras superfamily. J Mol Biol 301(4):1077-1087.
-
(2000)
J Mol Biol
, vol.301
, Issue.4
, pp. 1077-1087
-
-
Pereira-Leal, J.B.1
Seabra, M.C.2
-
20
-
-
0142178212
-
Structure of Rab GDP-dissociation inhibitor in complex with prenylated YPT1 GTPase
-
Rak A, et al. (2003) Structure of Rab GDP-dissociation inhibitor in complex with prenylated YPT1 GTPase. Science 302(5645):646-650.
-
(2003)
Science
, vol.302
, Issue.5645
, pp. 646-650
-
-
Rak, A.1
-
21
-
-
33750728028
-
Quantitative understanding of the energy transfer between fluorescent proteins connected via flexible peptide linkers
-
Evers TH, van Dongen EM, Faesen AC, Meijer EW, Merkx M (2006) Quantitative understanding of the energy transfer between fluorescent proteins connected via flexible peptide linkers. Biochemistry 45(44):13183-13192.
-
(2006)
Biochemistry
, vol.45
, Issue.44
, pp. 13183-13192
-
-
Evers, T.H.1
Van Dongen, E.M.2
Faesen, A.C.3
Meijer, E.W.4
Merkx, M.5
-
22
-
-
33845431710
-
A protein fluorescence amplifier: Continuous fluorometric assay for rab geranylgeranyltransferase
-
Wu YW, et al. (2006) A protein fluorescence amplifier: Continuous fluorometric assay for rab geranylgeranyltransferase. ChemBioChem 7(12):1859-1861.
-
(2006)
ChemBioChem
, vol.7
, Issue.12
, pp. 1859-1861
-
-
Wu, Y.W.1
-
23
-
-
0028261425
-
Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis
-
Stenmark H, et al. (1994) Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis. EMBO J 13(6):1287-1296.
-
(1994)
EMBO J
, vol.13
, Issue.6
, pp. 1287-1296
-
-
Stenmark, H.1
-
24
-
-
0035937112
-
Isoprenylcysteine carboxyl methyltransferase deficiency in mice
-
Bergo MO, et al. (2001) Isoprenylcysteine carboxyl methyltransferase deficiency in mice. J Biol Chem 276(8):5841-5845.
-
(2001)
J Biol Chem
, vol.276
, Issue.8
, pp. 5841-5845
-
-
Bergo, M.O.1
-
25
-
-
0027180460
-
Post-translational processing and membrane association of the two early endosome-associated rab GTP-binding proteins (rab4 and rab5)
-
Li G, Stahl PD (1993) Post-translational processing and membrane association of the two early endosome-associated rab GTP-binding proteins (rab4 and rab5). Arch Biochem Biophys 304(2):471-478.
-
(1993)
Arch Biochem Biophys
, vol.304
, Issue.2
, pp. 471-478
-
-
Li, G.1
Stahl, P.D.2
-
26
-
-
0028153018
-
Geranylgeranylated Rab proteins terminating in Cys-Ala-Cys, but not Cys-Cys, are carboxyl-methylated by bovine brain membranes in vitro
-
Smeland TE, Seabra MC, Goldstein JL, Brown MS (1994) Geranylgeranylated Rab proteins terminating in Cys-Ala-Cys, but not Cys-Cys, are carboxyl-methylated by bovine brain membranes in vitro. Proc Natl Acad Sci USA 91(22):10712-10716.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, Issue.22
, pp. 10712-10716
-
-
Smeland, T.E.1
Seabra, M.C.2
Goldstein, J.L.3
Brown, M.S.4
-
27
-
-
0038247888
-
Membrane targeting of Rab GTPases is influenced by the prenylation motif
-
Gomes AQ, et al. (2003) Membrane targeting of Rab GTPases is influenced by the prenylation motif. Mol Biol Cell 14(5):1882-1899.
-
(2003)
Mol Biol Cell
, vol.14
, Issue.5
, pp. 1882-1899
-
-
Gomes, A.Q.1
-
28
-
-
0032005206
-
Cytoskeletal proteins and Golgi dynamics
-
Lippincott-Schwartz J
-
Lippincott-Schwartz J (1998) Cytoskeletal proteins and Golgi dynamics. Curr Opin Cell Biol 10(1):52-59.
-
(1998)
Curr Opin Cell Biol
, vol.10
, Issue.1
, pp. 52-59
-
-
-
29
-
-
18444381428
-
Structural basis for recruitment of RILP by small GTPase Rab7
-
Wu M, Wang T, Loh E, Hong W, Song H (2005) Structural basis for recruitment of RILP by small GTPase Rab7. EMBO J 24(8):1491-1501.
-
(2005)
EMBO J
, vol.24
, Issue.8
, pp. 1491-1501
-
-
Wu, M.1
Wang, T.2
Loh, E.3
Hong, W.4
Song, H.5
-
30
-
-
33845313646
-
PI(3,45)P3 and PI(45)P2 lipids target proteins with polybasic clusters to the plasma membrane
-
Heo WD, et al. (2006) PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane. Science 314(5804):1458-1461.
-
(2006)
Science
, vol.314
, Issue.5804
, pp. 1458-1461
-
-
Heo, W.D.1
-
31
-
-
45449083834
-
The structural basis for activation of the Rab Ypt1p by the TRAPP membrane-tethering complexes
-
Cai Y, et al. (2008) The structural basis for activation of the Rab Ypt1p by the TRAPP membrane-tethering complexes. Cell 133(7):1202-1213.
-
(2008)
Cell
, vol.133
, Issue.7
, pp. 1202-1213
-
-
Cai, Y.1
-
32
-
-
34247596532
-
Structural basis for Rab GTPase activation by VPS9 domain exchange factors
-
Delprato A, Lambright DG (2007) Structural basis for Rab GTPase activation by VPS9 domain exchange factors. Nat Struct Mol Biol 14(5):406-412.
-
(2007)
Nat Struct Mol Biol
, vol.14
, Issue.5
, pp. 406-412
-
-
Delprato, A.1
Lambright, D.G.2
-
33
-
-
77954649564
-
Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1)
-
Mishra A, Eathiraj S, Corvera S, Lambright DG (2010) Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1). Proc Natl Acad Sci USA 107(24):10866-10871.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.24
, pp. 10866-10871
-
-
Mishra, A.1
Eathiraj, S.2
Corvera, S.3
Lambright, D.G.4
-
34
-
-
79960175612
-
Rab27a targeting to melanosomes requires nucleotide exchange but not effector binding
-
Tarafder AK, et al. (2011) Rab27a targeting to melanosomes requires nucleotide exchange but not effector binding. Traffic 12(8):1056-1066.
-
(2011)
Traffic
, vol.12
, Issue.8
, pp. 1056-1066
-
-
Tarafder, A.K.1
-
35
-
-
84874366009
-
RabGEFs are a major determinant for specific Rab membrane targeting
-
Blümer J, et al. (2013) RabGEFs are a major determinant for specific Rab membrane targeting. J Cell Biol 200(3):287-300.
-
(2013)
J Cell Biol
, vol.200
, Issue.3
, pp. 287-300
-
-
Blümer, J.1
-
36
-
-
77950460749
-
Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells
-
Kinchen JM, Ravichandran KS (2010) Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells. Nature 464(7289):778-782.
-
(2010)
Nature
, vol.464
, Issue.7289
, pp. 778-782
-
-
Kinchen, J.M.1
Ravichandran, K.S.2
-
37
-
-
77957231342
-
The Mon1-Ccz1 complex is the GEF of the late endosomal Rab7 homolog Ypt7
-
Nordmann M, et al. (2010) The Mon1-Ccz1 complex is the GEF of the late endosomal Rab7 homolog Ypt7. Curr Biol 20(18):1654-1659.
-
(2010)
Curr Biol
, vol.20
, Issue.18
, pp. 1654-1659
-
-
Nordmann, M.1
-
38
-
-
77951918362
-
Identification of the switch in early-to-late endosome transition
-
Poteryaev D, Datta S, Ackema K, Zerial M, Spang A (2010) Identification of the switch in early-to-late endosome transition. Cell 141(3):497-508.
-
(2010)
Cell
, vol.141
, Issue.3
, pp. 497-508
-
-
Poteryaev, D.1
Datta, S.2
Ackema, K.3
Zerial, M.4
Spang, A.5
-
39
-
-
70149084564
-
A Rab GAP cascade defines the boundary between two Rab GTPases on the secretory pathway
-
Rivera-Molina FE, Novick PJ (2009) A Rab GAP cascade defines the boundary between two Rab GTPases on the secretory pathway. Proc Natl Acad Sci USA 106(34):14408-14413.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.34
, pp. 14408-14413
-
-
Rivera-Molina, F.E.1
Novick, P.J.2
-
40
-
-
73949094671
-
Rabex-5 is a Rab22 effector and mediates a Rab22-Rab5 signaling cascade in endocytosis
-
Zhu H, Liang Z, Li G (2009) Rabex-5 is a Rab22 effector and mediates a Rab22-Rab5 signaling cascade in endocytosis. Mol Biol Cell 20(22):4720-4729.
-
(2009)
Mol Biol Cell
, vol.20
, Issue.22
, pp. 4720-4729
-
-
Zhu, H.1
Liang, Z.2
Li, G.3
-
41
-
-
68749097137
-
The localization of the Golgin GCC185 is independent of Rab6A/A' and Arl1
-
Houghton FJ, Chew PL, Lodeho S, Goud B, Gleeson PA (2009) The localization of the Golgin GCC185 is independent of Rab6A/A' and Arl1. Cell 138(4):787-794.
-
(2009)
Cell
, vol.138
, Issue.4
, pp. 787-794
-
-
Houghton, F.J.1
Chew, P.L.2
Lodeho, S.3
Goud, B.4
Gleeson, P.A.5
-
42
-
-
22944444569
-
Structural basis of family-wide Rab GTPase recognition by rabenosyn-5
-
Eathiraj S, Pan X, Ritacco C, Lambright DG (2005) Structural basis of family-wide Rab GTPase recognition by rabenosyn-5. Nature 436(7049):415-419.
-
(2005)
Nature
, vol.436
, Issue.7049
, pp. 415-419
-
-
Eathiraj, S.1
Pan, X.2
Ritacco, C.3
Lambright, D.G.4
|