-
1
-
-
79955830308
-
Protective role of heat shock proteins in Parkinson's disease
-
1:CAS:528:DC%2BC3MXlslKmtr4%3D 21212626 10.1159/000321548
-
Aridon P, Geraci F, Turturici G, D'Amelio M, Savettieri G, Sconzo G (2011) Protective role of heat shock proteins in Parkinson's disease. Neurodegener Dis 8:155-168
-
(2011)
Neurodegener Dis
, vol.8
, pp. 155-168
-
-
Aridon, P.1
Geraci, F.2
Turturici, G.3
D'Amelio, M.4
Savettieri, G.5
Sconzo, G.6
-
2
-
-
0031593748
-
The relationship between BcI2, Bax and p53: Consequences for cell cycle progression and cell death
-
1:CAS:528:DyaK1MXksVKnsA%3D%3D 9872359 10.1093/molehr/4.12.1099
-
Basu A, Haldar S (1998) The relationship between BcI2, Bax and p53: consequences for cell cycle progression and cell death. Mol Hum Reprod 4:1099-1109
-
(1998)
Mol Hum Reprod
, vol.4
, pp. 1099-1109
-
-
Basu, A.1
Haldar, S.2
-
3
-
-
37249007782
-
Hsp70 suppresses apoptosis in sympathetic neurones by preventing the activation of c-Jun
-
1:CAS:528:DC%2BD1cXhtFehtrs%3D 17971127
-
Bienemann AS, Lee YB, Howarth J, Uney JB (2008) Hsp70 suppresses apoptosis in sympathetic neurones by preventing the activation of c-Jun. J Neurochem 104:271-278
-
(2008)
J Neurochem
, vol.104
, pp. 271-278
-
-
Bienemann, A.S.1
Lee, Y.B.2
Howarth, J.3
Uney, J.B.4
-
4
-
-
0034993599
-
Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: Contribution to the apoptotic theory in Parkinson's disease
-
1:CAS:528:DC%2BD3MXkt1Kitbo%3D 11403877 10.1016/S0301-0082(01)00003-X
-
Blum D, Torch S, Lambeng N et al (2001) Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease. Prog Neurobiol 65:135-172
-
(2001)
Prog Neurobiol
, vol.65
, pp. 135-172
-
-
Blum, D.1
Torch, S.2
Lambeng, N.3
-
5
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
1:CAS:528:DyaE28XksVehtrY%3D 942051 10.1016/0003-2697(76)90527-3
-
Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
6
-
-
35548939457
-
Heat shock proteins and protection of the nervous system
-
1:CAS:528:DC%2BD2sXhsVanurfI 17656567 10.1196/annals.1391.032
-
Brown IR (2007) Heat shock proteins and protection of the nervous system. Ann N Y Acad Sci 1113:147-158
-
(2007)
Ann N y Acad Sci
, vol.1113
, pp. 147-158
-
-
Brown, I.R.1
-
7
-
-
26844537386
-
Increased nuclear factor-erythroid 2 p45-related factor 2 activity protects SH-SY5Y cells against oxidative damage
-
1:CAS:528:DC%2BD2MXhtFegu7vL 16092930 10.1111/j.1471-4159.2005.03377.x
-
Cao TT, Ma L, Kandpal G, Warren L, Hess JF, Seabrook GR (2005) Increased nuclear factor-erythroid 2 p45-related factor 2 activity protects SH-SY5Y cells against oxidative damage. J Neurochem 95:406-417
-
(2005)
J Neurochem
, vol.95
, pp. 406-417
-
-
Cao, T.T.1
Ma, L.2
Kandpal, G.3
Warren, L.4
Hess, J.F.5
Seabrook, G.R.6
-
8
-
-
20444415298
-
Adaptation to hydrogen peroxide enhances PC12 cell tolerance against oxidative damage
-
Chen ZH, Yoshida Y, Saito Y, Niki E (2005) Adaptation to hydrogen peroxide enhances PC12 cell tolerance against oxidative damage. Neurosci Lett 383:256-259
-
(2005)
Neurosci Lett
, vol.383
, pp. 256-259
-
-
Zh, C.1
Yoshida, Y.2
Saito, Y.3
Niki, E.4
-
9
-
-
0033168508
-
Two distinct mechanisms are involved in 6-hydroxydopamine- and MPP +-induced dopaminergic neuronal cell death: Role of caspases, ROS, and JNK
-
1:CAS:528:DyaK1MXktFCht7s%3D 10397638 10.1002/(SICI)1097-4547(19990701) 57:1<86: AID-JNR9>3.0.CO;2-E
-
Choi WS, Yoon SY, Oh TH, Choi EJ, O'Malley KL, Oh YJ (1999) Two distinct mechanisms are involved in 6-hydroxydopamine- and MPP +-induced dopaminergic neuronal cell death: role of caspases, ROS, and JNK. J Neurosci Res 57:86-94
-
(1999)
J Neurosci Res
, vol.57
, pp. 86-94
-
-
Choi, W.S.1
Yoon, S.Y.2
Oh, T.H.3
Choi, E.J.4
O'Malley, K.L.5
Oh, Y.J.6
-
10
-
-
0031873752
-
The 90-kDa molecular chaperone family: Structure, function, and clinical applications. A comprehensive review
-
1:CAS:528:DyaK1cXltVOktrc%3D 9749880 10.1016/S0163-7258(98)00013-8
-
Csermely P, Schnaider T, Soti C, Prohászka Z, Nardai G (1998) The 90-kDa molecular chaperone family: structure, function, and clinical applications. A comprehensive review. Pharmacol Ther 79:129-168
-
(1998)
Pharmacol Ther
, vol.79
, pp. 129-168
-
-
Csermely, P.1
Schnaider, T.2
Soti, C.3
Prohászka, Z.4
Nardai, G.5
-
11
-
-
65549095883
-
The transcription factor Nrf2 as a new therapeutic target in Parkinson's disease
-
1:CAS:528:DC%2BD1MXitFKnu74%3D 19236154 10.1517/13543780802716501
-
Cuadrado A, Moreno-Murciano P, Pedraza-Chaverri J (2009) The transcription factor Nrf2 as a new therapeutic target in Parkinson's disease. Expert Opin Ther Targets 13:319-329
-
(2009)
Expert Opin Ther Targets
, vol.13
, pp. 319-329
-
-
Cuadrado, A.1
Moreno-Murciano, P.2
Pedraza-Chaverri, J.3
-
12
-
-
0035394668
-
Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice
-
1:CAS:528:DC%2BD3MXlsFOgu7w%3D 11448943 10.1093/hmg/10.14.1511
-
Cummings CJ, Sun Y, Opal P et al (2001) Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice. Hum Mol Genet 10:1511-1518
-
(2001)
Hum Mol Genet
, vol.10
, pp. 1511-1518
-
-
Cummings, C.J.1
Sun, Y.2
Opal, P.3
-
13
-
-
0242363670
-
Molecular pathways of neurodegeneration in Parkinson's disease
-
1:CAS:528:DC%2BD3sXos1Cmt7w%3D 14593166 10.1126/science.1087753
-
Dawson TM, Dawson VL (2003) Molecular pathways of neurodegeneration in Parkinson's disease. Science 302:819-822
-
(2003)
Science
, vol.302
, pp. 819-822
-
-
Dawson, T.M.1
Dawson, V.L.2
-
14
-
-
10944241135
-
Hsp70 gene transfer by adeno-associated virus inhibits MPTP-induced nigrostriatal degeneration in the mouse model of Parkinson disease
-
1:CAS:528:DC%2BD2cXhtVCls7rP 15585408 10.1016/j.ymthe.2004.09.007
-
Dong Z, Wolfer DP, Lipp HP, Bueler H (2005) Hsp70 gene transfer by adeno-associated virus inhibits MPTP-induced nigrostriatal degeneration in the mouse model of Parkinson disease. Mol Ther 11:80-88
-
(2005)
Mol Ther
, vol.11
, pp. 80-88
-
-
Dong, Z.1
Wolfer, D.P.2
Lipp, H.P.3
Bueler, H.4
-
15
-
-
3042934967
-
Tissue sulfhydryl groups
-
1:CAS:528:DyaG1MXotl2ksA%3D%3D 13650640 10.1016/0003-9861(59)90090-6
-
Ellman GL (1959) Tissue sulfhydryl groups. Arch Biochem Biophys 82:70-77
-
(1959)
Arch Biochem Biophys
, vol.82
, pp. 70-77
-
-
Ellman, G.L.1
-
16
-
-
0033057848
-
Heat-shock proteins, molecular chaperones, and the stress response: Evolutionary and ecological physiology
-
1:CAS:528:DyaK1MXitVejs7o%3D 10099689 10.1146/annurev.physiol.61.1.243
-
Feder ME, Hofmann GE (1999) Heat-shock proteins, molecular chaperones, and the stress response: evolutionary and ecological physiology. Annu Rev Physiol 61:243-282
-
(1999)
Annu Rev Physiol
, vol.61
, pp. 243-282
-
-
Feder, M.E.1
Hofmann, G.E.2
-
17
-
-
24944525045
-
Molecular pathogenesis of Parkinson's disease
-
10.1093/hmg/ddi308
-
Gandhi S, Wood NW (2005) Molecular pathogenesis of Parkinson's disease. Hum Mol Genet 2:2749-2755
-
(2005)
Hum Mol Genet
, vol.2
, pp. 2749-2755
-
-
Gandhi, S.1
Wood, N.W.2
-
18
-
-
33646849308
-
6-Hydroxydopamine-induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase Cdelta
-
1:CAS:528:DC%2BD28XhvVejs7w%3D 16361258 10.1074/jbc.M511560200
-
Hanrott K, Gudmunsen L, O'Neill MJ, Wonnacott S (2006) 6-Hydroxydopamine-induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase Cdelta. J Biol Chem 281:5373-5382
-
(2006)
J Biol Chem
, vol.281
, pp. 5373-5382
-
-
Hanrott, K.1
Gudmunsen, L.2
O'Neill, M.J.3
Wonnacott, S.4
-
19
-
-
33748581394
-
Apomorphine protects against 6-hydroxydopamine-induced neuronal cell death through activation of the Nrf2-ARE pathway
-
1:CAS:528:DC%2BD28XpvVGjsLk%3D 16802348 10.1002/jnr.20974
-
Hara H, Ohta M, Adachi T (2006) Apomorphine protects against 6-hydroxydopamine-induced neuronal cell death through activation of the Nrf2-ARE pathway. J Neurosci Res 84:860-866
-
(2006)
J Neurosci Res
, vol.84
, pp. 860-866
-
-
Hara, H.1
Ohta, M.2
Adachi, T.3
-
20
-
-
0035033952
-
Signalling for survival and death in neurons: The role of stress-activated kinases, JNK and p38
-
1:CAS:528:DC%2BD3MXjsFehurY%3D 11369511 10.1016/S0898-6568(01)00148-6
-
Harper SJ, LoGrasso P (2001) Signalling for survival and death in neurons: the role of stress-activated kinases, JNK and p38. Cell Signal 13:299-310
-
(2001)
Cell Signal
, vol.13
, pp. 299-310
-
-
Harper, S.J.1
Lograsso, P.2
-
21
-
-
84877738587
-
Activation of the antioxidant response in methionine deprived human cells results in an HSF1-independent increase in HSPA1A mRNA levels
-
1:CAS:528:DC%2BC3sXislyktbY%3D 23395854 10.1016/j.biochi.2013.01.017
-
Hensen SM, Heldens L, van Enckevort CM, van Genesen ST, Pruijn GJ, Lubsen NH (2013) Activation of the antioxidant response in methionine deprived human cells results in an HSF1-independent increase in HSPA1A mRNA levels. Biochimie 95:1245-1251
-
(2013)
Biochimie
, vol.95
, pp. 1245-1251
-
-
Hensen, S.M.1
Heldens, L.2
Van Enckevort, C.M.3
Van Genesen, S.T.4
Pruijn, G.J.5
Lubsen, N.H.6
-
22
-
-
24044447603
-
Induction of the protective antioxidant response element pathway by 6-hydroxydopamine in vivo and in vitro
-
1:CAS:528:DC%2BD2MXovVOjsbs%3D 15976186 10.1093/toxsci/kfi241
-
Jakel RJ, Kern JT, Johnson DA, Johnson JA (2005) Induction of the protective antioxidant response element pathway by 6-hydroxydopamine in vivo and in vitro. Toxicol Sci 87:176-186
-
(2005)
Toxicol Sci
, vol.87
, pp. 176-186
-
-
Jakel, R.J.1
Kern, J.T.2
Johnson, D.A.3
Johnson, J.A.4
-
23
-
-
33947307990
-
Nrf2-mediated protection against 6-hydroxydopamine
-
1:CAS:528:DC%2BD2sXjsVWhtbs%3D 2062573 17336276 10.1016/j.brainres.2007. 01.131
-
Jakel RJ, Townsend JA, Kraft AD, Johnson JA (2007) Nrf2-mediated protection against 6-hydroxydopamine. Brain Res 1144:192-201
-
(2007)
Brain Res
, vol.1144
, pp. 192-201
-
-
Jakel, R.J.1
Townsend, J.A.2
Kraft, A.D.3
Johnson, J.A.4
-
24
-
-
78649239916
-
Molecular chaperones as rational drug targets for Parkinson's disease therapeutics
-
1:CAS:528:DC%2BC3cXhsFarsbrM 3364514 20942788 10.2174/187152710793237386
-
Kalia SK, Kalia LV, McLean PJ (2010) Molecular chaperones as rational drug targets for Parkinson's disease therapeutics. CNS Neurol Disord Drug Targets 9:741-753
-
(2010)
CNS Neurol Disord Drug Targets
, vol.9
, pp. 741-753
-
-
Kalia, S.K.1
Kalia, L.V.2
McLean, P.J.3
-
25
-
-
64149121709
-
Induction of heat shock proteins for protection against oxidative stress
-
1:CAS:528:DC%2BD1MXkslOqsbs%3D 19248813 10.1016/j.addr.2009.02.003
-
Kalmar B, Greensmith L (2009) Induction of heat shock proteins for protection against oxidative stress. Adv Drug Deliv Rev 61:310-318
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 310-318
-
-
Kalmar, B.1
Greensmith, L.2
-
26
-
-
33846493549
-
Association of heat shock protein 70 induction and the amelioration of experimental autoimmune uveoretinitis in mice
-
1:CAS:528:DC%2BD2sXjsFCis7k%3D 17270705 10.1016/j.imbio.2006.08.004
-
Kitamei H, Kitaichi N, Yoshida K et al (2007) Association of heat shock protein 70 induction and the amelioration of experimental autoimmune uveoretinitis in mice. Immunobiology 212:11-18
-
(2007)
Immunobiology
, vol.212
, pp. 11-18
-
-
Kitamei, H.1
Kitaichi, N.2
Yoshida, K.3
-
27
-
-
4043112106
-
The induction of heat shock proteins as a potential strategy to treat neurodegenerative disorders
-
1:CAS:528:DC%2BD2cXnt1entLs%3D 15334179 10.1358/dnp.2004.17.5.829033
-
Klettner A (2004) The induction of heat shock proteins as a potential strategy to treat neurodegenerative disorders. Drug News Perspect 17:299-306
-
(2004)
Drug News Perspect
, vol.17
, pp. 299-306
-
-
Klettner, A.1
-
28
-
-
0037434737
-
Nrf2 is an inhibitor of the Fas pathway as identified by Achilles' Heel Method, a new function-based approach to gene identification in human cells
-
1:CAS:528:DC%2BD3sXhtFSmt7w%3D 12584558 10.1038/sj.onc.1206077
-
Kotlo KU, Yehiely F, Efimova E, Harasty H, Hesabi B, Shchors K, Einat P, Rozen A, Berent E, Deiss LP (2003) Nrf2 is an inhibitor of the Fas pathway as identified by Achilles' Heel Method, a new function-based approach to gene identification in human cells. Oncogene 22:797-806
-
(2003)
Oncogene
, vol.22
, pp. 797-806
-
-
Kotlo, K.U.1
Yehiely, F.2
Efimova, E.3
Harasty, H.4
Hesabi, B.5
Shchors, K.6
Einat, P.7
Rozen, A.8
Berent, E.9
Deiss, L.P.10
-
29
-
-
0345306813
-
Aspirin prevents apoptosis and NF-kappaB activation induced by H2O2 in hela cells
-
1:CAS:528:DC%2BD3sXpsVClsrc%3D 14753751 10.1080/10715760310001616005
-
Kutuk O, Basaga H (2003) Aspirin prevents apoptosis and NF-kappaB activation induced by H2O2 in hela cells. Free Radic Res 37:1267-1276
-
(2003)
Free Radic Res
, vol.37
, pp. 1267-1276
-
-
Kutuk, O.1
Basaga, H.2
-
30
-
-
2342514015
-
An important role of Nrf2-ARE pathway in the cellular defense mechanism
-
1:CAS:528:DC%2BD2cXjtFWlur4%3D 15469687 10.5483/BMBRep.2004.37.2.139
-
Lee JM, Johnson JA (2004) An important role of Nrf2-ARE pathway in the cellular defense mechanism. J Biochem Mol Biol 37:139-143
-
(2004)
J Biochem Mol Biol
, vol.37
, pp. 139-143
-
-
Lee, J.M.1
Johnson, J.A.2
-
31
-
-
0033557640
-
Distinct mechanisms underlie neurotoxin-mediated cell death in cultured dopaminergic neurons
-
1:CAS:528:DyaK1MXhtFOhsrw%3D 9952406
-
Lotharius J, Dugan LL, O'Malley KL (1999) Distinct mechanisms underlie neurotoxin-mediated cell death in cultured dopaminergic neurons. J Neurosci 19:1284-1293
-
(1999)
J Neurosci
, vol.19
, pp. 1284-1293
-
-
Lotharius, J.1
Dugan, L.L.2
O'Malley, K.L.3
-
32
-
-
84867034260
-
Role of nrf2 in oxidative stress and toxicity
-
1:CAS:528:DC%2BC3sXjt1Wguro%3D 23294312 10.1146/annurev-pharmtox-011112- 140320
-
Ma Q (2013) Role of nrf2 in oxidative stress and toxicity. Annu Rev Pharmacol Toxicol 53:401-426
-
(2013)
Annu Rev Pharmacol Toxicol
, vol.53
, pp. 401-426
-
-
Ma, Q.1
-
33
-
-
33645159024
-
RNA knockdown as a potential therapeutic strategy in Parkinson's disease
-
1:CAS:528:DC%2BD28XitVGnurc%3D 16267570 10.1038/sj.gt.3302669
-
Manfredsson FP, Lewin AS, Mandel RJ (2006) RNA knockdown as a potential therapeutic strategy in Parkinson's disease. Gene Ther 13:517-524
-
(2006)
Gene Ther
, vol.13
, pp. 517-524
-
-
Manfredsson, F.P.1
Lewin, A.S.2
Mandel, R.J.3
-
34
-
-
34147180058
-
Evaluation of locked nucleic acid-modified small interfering RNA in vitro and in vivo
-
1:CAS:528:DC%2BD2sXivV2ntb8%3D 17363479 10.1158/1535-7163.MCT-06-0195
-
Mook OR, Baas F, de Wissel MB, Fluiter K (2007) Evaluation of locked nucleic acid-modified small interfering RNA in vitro and in vivo. Mol Cancer Ther 6:833-843
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 833-843
-
-
Mook, O.R.1
Baas, F.2
De Wissel, M.B.3
Fluiter, K.4
-
35
-
-
42249103388
-
Tat-Hsp70 protects dopaminergic neurons in midbrain cultures and in the substantia nigra in models of Parkinson's disease
-
1:CAS:528:DC%2BD1cXlsl2hu7c%3D 18182047 10.1111/j.1471-4159.2007.05204.x
-
Nagel F, Falkenburger BH, Tönges L, Kowsky S, Pöppelmeyer C, Schulz JB, Bähr M, Dietz GP (2008) Tat-Hsp70 protects dopaminergic neurons in midbrain cultures and in the substantia nigra in models of Parkinson's disease. J Neurochem 105:853-864
-
(2008)
J Neurochem
, vol.105
, pp. 853-864
-
-
Nagel, F.1
Falkenburger, B.H.2
Tönges, L.3
Kowsky, S.4
Pöppelmeyer, C.5
Schulz, J.B.6
Bähr, M.7
Dietz, G.P.8
-
36
-
-
78449240947
-
Hsp90 interaction with INrf2(Keap1) mediates stress-induced Nrf2 activation
-
1:CAS:528:DC%2BC3cXhsVWgsrjO 20864537 10.1074/jbc.M110.175802
-
Niture SK, Jaiswal AK (2010) Hsp90 interaction with INrf2(Keap1) mediates stress-induced Nrf2 activation. J Biol Chem 285:36865-36875
-
(2010)
J Biol Chem
, vol.285
, pp. 36865-36875
-
-
Niture, S.K.1
Jaiswal, A.K.2
-
37
-
-
84858964113
-
Nrf2 protein up-regulates antiapoptotic protein Bcl-2 and prevents cellular apoptosis
-
1:CAS:528:DC%2BC38XktlKrtLc%3D 22275372 10.1074/jbc.M111.312694
-
Niture SK, Jaiswal AK (2012) Nrf2 protein up-regulates antiapoptotic protein Bcl-2 and prevents cellular apoptosis. J Biol Chem 287:9873-9886
-
(2012)
J Biol Chem
, vol.287
, pp. 9873-9886
-
-
Niture, S.K.1
Jaiswal, A.K.2
-
38
-
-
0031775603
-
Caspases mediate 6-hydroxydopamine-induced apoptosis but not necrosis in PC12 cells
-
1:CAS:528:DyaK1cXjsVGktb0%3D 9603231 10.1046/j.1471-4159.1998.70062637.x
-
Ochu EE, Rothwell NJ, Waters CM (1998) Caspases mediate 6-hydroxydopamine-induced apoptosis but not necrosis in PC12 cells. J Neurochem 70:2637-2640
-
(1998)
J Neurochem
, vol.70
, pp. 2637-2640
-
-
Ochu, E.E.1
Rothwell, N.J.2
Waters, C.M.3
-
39
-
-
32844470038
-
AEG3482 is an antiapoptotic compound that inhibits Jun kinase activity and cell death through induced expression of heat shock protein 90
-
1:CAS:528:DC%2BD28XhvVemsrw%3D 16492569 10.1016/j.chembiol.2005.11.012
-
Salehi AH, Morris SJ, Ho W-C et al (2006) AEG3482 is an antiapoptotic compound that inhibits Jun kinase activity and cell death through induced expression of heat shock protein 90. Chem Biol 13:213-223
-
(2006)
Chem Biol
, vol.13
, pp. 213-223
-
-
Salehi, A.H.1
Morris, S.J.2
Ho, W.-C.3
-
40
-
-
0035003439
-
Chemistry and biochemistry of oxidative stress in neurodegenerative disease
-
1:CAS:528:DC%2BD3MXjsVChtbs%3D 11375746 10.2174/0929867013372922
-
Sayre LM, Smith MA, Perry G (2001) Chemistry and biochemistry of oxidative stress in neurodegenerative disease. Curr Med Chem 8:721-738
-
(2001)
Curr Med Chem
, vol.8
, pp. 721-738
-
-
Sayre, L.M.1
Smith, M.A.2
Perry, G.3
-
41
-
-
79957606041
-
Etiology and pathogenesis of Parkinson's disease
-
21626550 10.1002/mds.23732
-
Schapira AH, Jenner P (2011) Etiology and pathogenesis of Parkinson's disease. Mov Disord 26:1049-1055
-
(2011)
Mov Disord
, vol.26
, pp. 1049-1055
-
-
Schapira, A.H.1
Jenner, P.2
-
42
-
-
28844451001
-
Geldanamycin induces heat shock protein 70 and protects against MPTP-induced dopaminergic neurotoxicity in mice
-
1:CAS:528:DC%2BD2MXht1Gjs7%2FI 16210323 10.1074/jbc.M505524200
-
Shen HY, He JC, Wang Y, Huang QY, Chen JF (2005) Geldanamycin induces heat shock protein 70 and protects against MPTP-induced dopaminergic neurotoxicity in mice. J Biol Chem 280:39962-39969
-
(2005)
J Biol Chem
, vol.280
, pp. 39962-39969
-
-
Shen, H.Y.1
He, J.C.2
Wang, Y.3
Huang, Q.Y.4
Chen, J.F.5
-
43
-
-
65849512212
-
Nrf2 activators provide neuroprotection against 6-hydroxydopamine toxicity in rat organotypic nigrostriatal cocultures
-
1:CAS:528:DC%2BD1MXltFartb4%3D 19125416 10.1002/jnr.21975
-
Siebert A, Desai V, Chandrasekaran K, Fiskum G, Jafri MS (2009) Nrf2 activators provide neuroprotection against 6-hydroxydopamine toxicity in rat organotypic nigrostriatal cocultures. J Neurosci Res 87:1659-1669
-
(2009)
J Neurosci Res
, vol.87
, pp. 1659-1669
-
-
Siebert, A.1
Desai, V.2
Chandrasekaran, K.3
Fiskum, G.4
Jafri, M.S.5
-
44
-
-
33244474580
-
Hsp70 inhibits heat-induced apoptosis upstream of mitochondria by preventing Bax translocation
-
1:CAS:528:DC%2BD2MXht1SktLjE 16172114 10.1074/jbc.M509497200
-
Stankiewicz AR, Lachapelle G, Foo CP, Radicioni SM, Mosser DD (2005) Hsp70 inhibits heat-induced apoptosis upstream of mitochondria by preventing Bax translocation. J Biol Chem 280:38729-38739
-
(2005)
J Biol Chem
, vol.280
, pp. 38729-38739
-
-
Stankiewicz, A.R.1
Lachapelle, G.2
Foo, C.P.3
Radicioni, S.M.4
Mosser, D.D.5
-
45
-
-
78049348191
-
Parkinson's disease: Oxidative stress and therapeutic approaches
-
20221655 10.1007/s10072-010-0245-1
-
Surendran S, Rajasankar S (2010) Parkinson's disease: oxidative stress and therapeutic approaches. Neurol Sci 31:531-540
-
(2010)
Neurol Sci
, vol.31
, pp. 531-540
-
-
Surendran, S.1
Rajasankar, S.2
-
47
-
-
68649112842
-
Oxidative and nitrosative stress in Parkinson's disease
-
1:CAS:528:DC%2BD1MXnsFygsrc%3D 19162179 10.1016/j.bbadis.2008.12.006
-
Tsang AH, Chung KK (2009) Oxidative and nitrosative stress in Parkinson's disease. Biochim Biophys Acta 1792:643-650
-
(2009)
Biochim Biophys Acta
, vol.1792
, pp. 643-650
-
-
Tsang, A.H.1
Chung, K.K.2
-
48
-
-
0032727617
-
Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70
-
1:CAS:528:DyaK1MXnvFOktbo%3D 10581028 10.1038/70532
-
Warrick JM, Chan HY, Gray-Board GL, Chai Y, Paulson HL, Bonini NM (1999) Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70. Nat Genet 23:425-428
-
(1999)
Nat Genet
, vol.23
, pp. 425-428
-
-
Warrick, J.M.1
Chan, H.Y.2
Gray-Board, G.L.3
Chai, Y.4
Paulson, H.L.5
Bonini, N.M.6
-
49
-
-
0032963521
-
The toxicity of 6-hydroxydopamine on PC12 and P19 cells
-
1:CAS:528:DyaK1MXjsVShuro%3D 10350640 10.1016/S0169-328X(99)00103-5
-
Woodgate A, MacGibbon G, Walton M, Dragunow M (1999) The toxicity of 6-hydroxydopamine on PC12 and P19 cells. Brain Res Mol Brain Res 69:84-92
-
(1999)
Brain Res Mol Brain Res
, vol.69
, pp. 84-92
-
-
Woodgate, A.1
Macgibbon, G.2
Walton, M.3
Dragunow, M.4
-
50
-
-
82255181180
-
HSF1-dependent upregulation of Hsp70 by sulfhydryl-reactive inducers of the KEAP1/NRF2/ARE pathway
-
1:CAS:528:DC%2BC3MXhsFeqs7jE 3302153 22118669 10.1016/j.chembiol.2011.09. 008
-
Zhang Y, Ahn YH, Benjamin IJ, Honda T, Hicks RJ, Calabrese V, Cole PA, Dinkova-Kostova AT (2011) HSF1-dependent upregulation of Hsp70 by sulfhydryl-reactive inducers of the KEAP1/NRF2/ARE pathway. Chem Biol 18:1355-1361
-
(2011)
Chem Biol
, vol.18
, pp. 1355-1361
-
-
Zhang, Y.1
Ahn, Y.H.2
Benjamin, I.J.3
Honda, T.4
Hicks, R.J.5
Calabrese, V.6
Cole, P.A.7
Dinkova-Kostova, A.T.8
-
51
-
-
4644291645
-
Analysis of alpha-synuclein-associated proteins by quantitative proteomics
-
1:CAS:528:DC%2BD2cXnt1yjtrY%3D 15234983 10.1074/jbc.M405456200
-
Zhou Y, Gu G, Goodlett DR, Zhang T, Pan C, Montine TJ, Montine KS, Aebersold RH, Zhang J (2004) Analysis of alpha-synuclein-associated proteins by quantitative proteomics. J Biol Chem 279:39155-39164
-
(2004)
J Biol Chem
, vol.279
, pp. 39155-39164
-
-
Zhou, Y.1
Gu, G.2
Goodlett, D.R.3
Zhang, T.4
Pan, C.5
Montine, T.J.6
Montine, K.S.7
Aebersold, R.H.8
Zhang, J.9
-
52
-
-
57649155208
-
Oxidative stress in Parkinson's disease: A mechanism of pathogenic and therapeutic significance
-
1:CAS:528:DC%2BD1MXhsVaqtbs%3D 2745097 19076434 10.1196/annals.1427.023
-
Zhou C, Huang Y, Przedborski S (2008) Oxidative stress in Parkinson's disease: a mechanism of pathogenic and therapeutic significance. Ann N Y Acad Sci 1147:93-104
-
(2008)
Ann N y Acad Sci
, vol.1147
, pp. 93-104
-
-
Zhou, C.1
Huang, Y.2
Przedborski, S.3
|