메뉴 건너뛰기




Volumn 8, Issue 11, 2013, Pages

Identification of miR-30e* regulation of bmi1 expression mediated by tumor-associated macrophages in gastrointestinal cancer

Author keywords

[No Author keywords available]

Indexed keywords

BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE, TUMOR; COCULTURE TECHNIQUES; GASTROINTESTINAL NEOPLASMS; GENE EXPRESSION REGULATION; HUMANS; MACROPHAGES; MICRORNAS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYCOMB REPRESSIVE COMPLEX 1; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84894265866     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081839     Document Type: Article
Times cited : (52)

References (35)
  • 1
    • 4644319204 scopus 로고    scopus 로고
    • Stem cells and cancer; the polycomb connection
    • doi:10.1016/j.cell.2004.08.005. PubMed: 15315754
    • Valk-Lingbeek ME, Bruggeman SW, van Lohuizen M (2004) Stem cells and cancer; the polycomb connection. Cell 118: 409-418. doi:10.1016/j.cell.2004.08. 005. PubMed: 15315754.
    • (2004) Cell , vol.118 , pp. 409-418
    • Valk-Lingbeek, M.E.1    Bruggeman, S.W.2    Van Lohuizen, M.3
  • 2
    • 33846576622 scopus 로고    scopus 로고
    • Epigenetic stem cell signature in cancer
    • doi:10.1038/ng1941. PubMed: 17200673
    • Widschwendter M, Fiegl H, Egle D, Mueller-Holzner E, Spizzo G et al. (2007) Epigenetic stem cell signature in cancer. Nat Genet 39: 157-158. doi:10.1038/ng1941. PubMed: 17200673.
    • (2007) Nat Genet , vol.39 , pp. 157-158
    • Widschwendter, M.1    Fiegl, H.2    Egle, D.3    Mueller-Holzner, E.4    Spizzo, G.5
  • 3
    • 0242667922 scopus 로고    scopus 로고
    • Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
    • doi:10.1038/nature02060. PubMed: 14574365
    • Molofsky AV, Pardal R, Iwashita T, Park IK, Clarke MF et al. (2003) Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 425: 962-967. doi:10.1038/nature02060. PubMed: 14574365.
    • (2003) Nature , vol.425 , pp. 962-967
    • Molofsky, A.V.1    Pardal, R.2    Iwashita, T.3    Park, I.K.4    Clarke, M.F.5
  • 4
    • 0033552813 scopus 로고    scopus 로고
    • The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
    • doi:10.1038/16476. PubMed: 9923679
    • Jacobs JJ, Kieboom K, Marino S, DePinho RA, van Lohuizen M (1999) The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature 397: 164-168. doi:10.1038/16476. PubMed: 9923679.
    • (1999) Nature , vol.397 , pp. 164-168
    • Jacobs, J.J.1    Kieboom, K.2    Marino, S.3    DePinho, R.A.4    Van Lohuizen, M.5
  • 5
    • 20544453888 scopus 로고    scopus 로고
    • Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice
    • doi:10.1101/gad.1299305. PubMed: 15964995
    • Bruggeman SW, Valk-Lingbeek ME, van der Stoop PP, Jacobs JJ, Kieboom K et al. (2005) Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice. Genes Dev 19: 1438-1443. doi:10.1101/gad.1299305. PubMed: 15964995.
    • (2005) Genes Dev , vol.19 , pp. 1438-1443
    • Bruggeman, S.W.1    Valk-Lingbeek, M.E.2    Van Der Stoop, P.P.3    Jacobs, J.J.4    Kieboom, K.5
  • 6
    • 10344258563 scopus 로고    scopus 로고
    • Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1
    • doi:10.1016/j.immuni.2004.11.004. PubMed: 15589172
    • Iwama A, Oguro H, Negishi M, Kato Y, Morita Y et al. (2004) Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1. Immunity 21: 843-851. doi:10.1016/j.immuni.2004.11.004. PubMed: 15589172.
    • (2004) Immunity , vol.21 , pp. 843-851
    • Iwama, A.1    Oguro, H.2    Negishi, M.3    Kato, Y.4    Morita, Y.5
  • 7
    • 46249128798 scopus 로고    scopus 로고
    • Bmi1 is expressed in vivo in intestinal stem cells
    • doi:10.1038/ng.165. PubMed: 18536716
    • Sangiorgi E, Capecchi MR (2008) Bmi1 is expressed in vivo in intestinal stem cells. Nat Genet 40: 915-920. doi:10.1038/ng.165. PubMed: 18536716.
    • (2008) Nat Genet , vol.40 , pp. 915-920
    • Sangiorgi, E.1    Capecchi, M.R.2
  • 8
    • 0027487387 scopus 로고
    • bmi-1 transgene induces lymphomas and collaborates with myc in tumorigenesis
    • PubMed: 8414519
    • Haupt Y, Bath ML, Harris AW, Adams JM (1993) bmi-1 transgene induces lymphomas and collaborates with myc in tumorigenesis. Oncogene 8: 3161-3164. PubMed: 8414519.
    • (1993) Oncogene , vol.8 , pp. 3161-3164
    • Haupt, Y.1    Bath, M.L.2    Harris, A.W.3    Adams, J.M.4
  • 9
    • 39749120638 scopus 로고    scopus 로고
    • Bmi-1 expression predicts prognosis for patients with gastric carcinoma
    • doi:10.1002/jso.20934. PubMed: 18041745
    • Liu JH, Song LB, Zhang X, Guo BH, Feng Y et al. (2008) Bmi-1 expression predicts prognosis for patients with gastric carcinoma. J Surg Oncol 97: 267-272. doi:10.1002/jso.20934. PubMed: 18041745.
    • (2008) J Surg Oncol , vol.97 , pp. 267-272
    • Liu, J.H.1    Song, L.B.2    Zhang, X.3    Guo, B.H.4    Feng, Y.5
  • 10
    • 77953232638 scopus 로고    scopus 로고
    • Expression level of Bmi-1 oncoprotein is associated with progression and prognosis in colon cancer
    • doi:10.1007/s00432-009-0745-7. PubMed: 20024662
    • Li DW, Tang HM, Fan JW, Yan DW, Zhou CZ et al. (2010) Expression level of Bmi-1 oncoprotein is associated with progression and prognosis in colon cancer. J Cancer Res Clin Oncol 136: 997-1006. doi:10.1007/s00432-009-0745-7. PubMed: 20024662.
    • (2010) J Cancer Res Clin Oncol , vol.136 , pp. 997-1006
    • Li, D.W.1    Tang, H.M.2    Fan, J.W.3    Yan, D.W.4    Zhou, C.Z.5
  • 11
    • 84863691003 scopus 로고    scopus 로고
    • Macrophages in tumor microenvironments and the progression of tumors
    • Hao NB, Lu MH, Fan YH, Cao YL, Zhang ZR, et al. (2012) Macrophages in tumor microenvironments and the progression of tumors. Clin Dev Immunol 2012: 948098
    • (2012) Clin Dev Immunol , vol.2012 , pp. 948098
    • Hao, N.B.1    Lu, M.H.2    Fan, Y.H.3    Cao, Y.L.4    Zhang, Z.R.5
  • 12
    • 33750813483 scopus 로고    scopus 로고
    • Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: New molecules and patterns of gene expression
    • PubMed: 17082649
    • Martinez FO, Gordon S, Locati M, Mantovani A (2006) Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J Immunol 177: 7303-7311. PubMed: 17082649.
    • (2006) J Immunol , vol.177 , pp. 7303-7311
    • Martinez, F.O.1    Gordon, S.2    Locati, M.3    Mantovani, A.4
  • 13
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • doi:10.1038/nri978. PubMed: 12511873
    • Gordon S (2003) Alternative activation of macrophages. Nat Rev Immunol 3: 23-35. doi:10.1038/nri978. PubMed: 12511873.
    • (2003) Nat Rev Immunol , vol.3 , pp. 23-35
    • Gordon, S.1
  • 14
    • 33645991795 scopus 로고    scopus 로고
    • Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy
    • doi:10.1016/j.ejca.2006.01.003. PubMed: 16520032
    • Sica A, Schioppa T, Mantovani A, Allavena P (2006) Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy. Eur J Cancer 42: 717-727. doi:10.1016/j.ejca.2006.01.003. PubMed: 16520032.
    • (2006) Eur J Cancer , vol.42 , pp. 717-727
    • Sica, A.1    Schioppa, T.2    Mantovani, A.3    Allavena, P.4
  • 15
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • doi:10.1038/nrc1256. PubMed: 14708027
    • Pollard JW (2004) Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 4: 71-78. doi:10.1038/nrc1256. PubMed: 14708027.
    • (2004) Nat Rev Cancer , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 16
    • 70349107704 scopus 로고    scopus 로고
    • Activated macrophages in the tumour microenvironment-dancing to the tune of TLR and NF-kappaB
    • doi:10.1002/path.2602. PubMed: 19662665
    • Hallam S, Escorcio-Correia M, Soper R, Schultheiss A, Hagemann T (2009) Activated macrophages in the tumour microenvironment-dancing to the tune of TLR and NF-kappaB. J Pathol 219: 143-152. doi:10.1002/path.2602. PubMed: 19662665.
    • (2009) J Pathol , vol.219 , pp. 143-152
    • Hallam, S.1    Escorcio-Correia, M.2    Soper, R.3    Schultheiss, A.4    Hagemann, T.5
  • 17
    • 84876424760 scopus 로고    scopus 로고
    • Macrophage regulation of tumor responses to anticancer therapies
    • doi:10.1016/j.ccr.2013.02.013. PubMed: 23518347
    • De Palma M, Lewis CE (2013) Macrophage regulation of tumor responses to anticancer therapies. Cancer Cell 23: 277-286. doi:10.1016/j.ccr.2013.02.013. PubMed: 23518347.
    • (2013) Cancer Cell , vol.23 , pp. 277-286
    • De Palma, M.1    Lewis, C.E.2
  • 18
    • 78651461701 scopus 로고    scopus 로고
    • HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF
    • doi:10.1016/j.ccr.2010.11.009. PubMed: 21215706
    • Rolny C, Mazzone M, Tugues S, Laoui D, Johansson I et al. (2011) HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF. Cancer Cell 19: 31-44. doi:10.1016/j.ccr.2010.11.009. PubMed: 21215706.
    • (2011) Cancer Cell , vol.19 , pp. 31-44
    • Rolny, C.1    Mazzone, M.2    Tugues, S.3    Laoui, D.4    Johansson, I.5
  • 19
    • 33846188098 scopus 로고    scopus 로고
    • microRNAs as oncogenes and tumor suppressors
    • doi:10.1016/j.ydbio.2006.08.028. PubMed: 16989803
    • Zhang B, Pan X, Cobb GP, Anderson TA (2007) microRNAs as oncogenes and tumor suppressors. Dev Biol 302: 1-12. doi:10.1016/j.ydbio.2006.08.028. PubMed: 16989803.
    • (2007) Dev Biol , vol.302 , pp. 1-12
    • Zhang, B.1    Pan, X.2    Cobb, G.P.3    Anderson, T.A.4
  • 20
    • 84861533055 scopus 로고    scopus 로고
    • microRNAs in cancer management
    • doi:10.1016/S1470-2045(12)70073-6. PubMed: 22652233
    • Kong YW, Ferland-McCollough D, Jackson TJ, Bushell M (2012) microRNAs in cancer management. Lancet Oncol 13: e249-e258. doi:10.1016/S1470-2045(12)70073- 6. PubMed: 22652233.
    • (2012) Lancet Oncol , vol.13
    • Kong, Y.W.1    Ferland-McCollough, D.2    Jackson, T.J.3    Bushell, M.4
  • 21
    • 33745685884 scopus 로고    scopus 로고
    • Bmi-1 is a novel molecular marker of nasopharyngeal carcinoma progression and immortalizes primary human nasopharyngeal epithelial cells
    • doi:10.1158/0008-5472.CAN-06-0094. PubMed: 16778197
    • Song LB, Zeng MS, Liao WT, Zhang L, Mo HY et al. (2006) Bmi-1 is a novel molecular marker of nasopharyngeal carcinoma progression and immortalizes primary human nasopharyngeal epithelial cells. Cancer Res 66: 6225-6232. doi:10.1158/0008-5472.CAN-06-0094. PubMed: 16778197.
    • (2006) Cancer Res , vol.66 , pp. 6225-6232
    • Song, L.B.1    Zeng, M.S.2    Liao, W.T.3    Zhang, L.4    Mo, H.Y.5
  • 22
    • 77954855351 scopus 로고    scopus 로고
    • Significance of alternatively activated macrophages in patients with intrahepatic cholangiocarcinoma
    • doi:10.1111/j.1349-7006.2010.01614.x. PubMed: 20545696
    • Hasita H, Komohara Y, Okabe H, Masuda T, Ohnishi K et al. (2010) Significance of alternatively activated macrophages in patients with intrahepatic cholangiocarcinoma. Cancer Sci 101: 1913-1919. doi:10.1111/j.1349- 7006.2010.01614.x. PubMed: 20545696.
    • (2010) Cancer Sci , vol.101 , pp. 1913-1919
    • Hasita, H.1    Komohara, Y.2    Okabe, H.3    Masuda, T.4    Ohnishi, K.5
  • 23
    • 63149154973 scopus 로고    scopus 로고
    • Tumor-associated macrophage-induced invasion and angiogenesis of human basal cell carcinoma cells by cyclooxygenase-2 induction
    • doi:10.1038/jid.2008.310. PubMed: 18843292
    • Tjiu JW, Chen JS, Shun CT, Lin SJ, Liao YH et al. (2009) Tumor-associated macrophage-induced invasion and angiogenesis of human basal cell carcinoma cells by cyclooxygenase-2 induction. J Invest Dermatol 129: 1016-1025. doi:10.1038/jid.2008.310. PubMed: 18843292.
    • (2009) J Invest Dermatol , vol.129 , pp. 1016-1025
    • Tjiu, J.W.1    Chen, J.S.2    Shun, C.T.3    Lin, S.J.4    Liao, Y.H.5
  • 24
    • 84874291853 scopus 로고    scopus 로고
    • Tumor-associated macrophages regulate murine breast cancer stem cells through a novel paracrine EGFR/Stat3/Sox-2 signaling pathway
    • doi:10.1002/stem.1281. PubMed: 23169551
    • Yang J, Liao D, Chen C, Liu Y, Chuang TH et al. (2013) Tumor-associated macrophages regulate murine breast cancer stem cells through a novel paracrine EGFR/Stat3/Sox-2 signaling pathway. Stem Cells 31: 248-258. doi:10.1002/stem. 1281. PubMed: 23169551.
    • (2013) Stem Cells , vol.31 , pp. 248-258
    • Yang, J.1    Liao, D.2    Chen, C.3    Liu, Y.4    Chuang, T.H.5
  • 25
    • 4143110195 scopus 로고    scopus 로고
    • Expression profiling identifies chemokine (C-C motif) ligand 18 as an independent prognostic indicator in gastric cancer
    • doi:10.1053/j.gastro.2004.05.031. PubMed: 15300578
    • Leung SY, Yuen ST, Chu KM, Mathy JA, Li R et al. (2004) Expression profiling identifies chemokine (C-C motif) ligand 18 as an independent prognostic indicator in gastric cancer. Gastroenterology 127: 457-469. doi:10.1053/j.gastro.2004.05.031. PubMed: 15300578.
    • (2004) Gastroenterology , vol.127 , pp. 457-469
    • Leung, S.Y.1    Yuen, S.T.2    Chu, K.M.3    Mathy, J.A.4    Li, R.5
  • 26
    • 38649136919 scopus 로고    scopus 로고
    • Tumor-infiltrating macrophages and dendritic cells in human colorectal cancer: Relation to local regulatory T cells, systemic T-cell response against tumor-associated antigens and survival
    • doi:10.1186/1479-5876-5-62. PubMed: 18047662
    • Nagorsen D, Voigt S, Berg E, Stein H, Thiel E et al. (2007) Tumor-infiltrating macrophages and dendritic cells in human colorectal cancer: relation to local regulatory T cells, systemic T-cell response against tumor-associated antigens and survival. J Transl Med 5: 62. doi:10.1186/1479- 5876-5-62. PubMed: 18047662.
    • (2007) J Transl Med , vol.5 , pp. 62
    • Nagorsen, D.1    Voigt, S.2    Berg, E.3    Stein, H.4    Thiel, E.5
  • 27
    • 77957583439 scopus 로고    scopus 로고
    • Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition
    • doi:10.1038/ncb2099. PubMed: 20818389
    • Yang MH, Hsu DS, Wang HW, Wang HJ, Lan HY et al. (2010) Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition. Nat Cell Biol 12: 982-992. doi:10.1038/ncb2099. PubMed: 20818389.
    • (2010) Nat Cell Biol , vol.12 , pp. 982-992
    • Yang, M.H.1    Hsu, D.S.2    Wang, H.W.3    Wang, H.J.4    Lan, H.Y.5
  • 28
    • 84873320012 scopus 로고    scopus 로고
    • A positive feedback loop regulates the expression of polycomb group protein BMI1 via WNT signaling pathway
    • doi:10.1074/jbc.M112.422931. PubMed: 23239878
    • Cho JH, Dimri M, Dimri GP (2013) A positive feedback loop regulates the expression of polycomb group protein BMI1 via WNT signaling pathway. J Biol Chem 288: 3406-3418. doi:10.1074/jbc.M112.422931. PubMed: 23239878.
    • (2013) J Biol Chem , vol.288 , pp. 3406-3418
    • Cho, J.H.1    Dimri, M.2    Dimri, G.P.3
  • 29
    • 84863050370 scopus 로고    scopus 로고
    • Regulation of the potential marker for intestinal cells, Bmi1, by beta-catenin and the zinc finger protein KLF4: Implications for colon cancer
    • doi:10.1074/jbc.M111.316349. PubMed: 22170051
    • Yu T, Chen X, Zhang W, Colon D, Shi J et al. (2012) Regulation of the potential marker for intestinal cells, Bmi1, by beta-catenin and the zinc finger protein KLF4: implications for colon cancer. J Biol Chem 287: 3760-3768. doi:10.1074/jbc.M111.316349. PubMed: 22170051.
    • (2012) J Biol Chem , vol.287 , pp. 3760-3768
    • Yu, T.1    Chen, X.2    Zhang, W.3    Colon, D.4    Shi, J.5
  • 30
    • 77955294582 scopus 로고    scopus 로고
    • MicroRNA 128a increases intracellular ROS level by targeting Bmi-1 and inhibits medulloblastoma cancer cell growth by promoting senescence
    • doi:10.1371/journal.pone.0010748. PubMed: 20574517
    • Venkataraman S, Alimova I, Fan R, Harris P, Foreman N et al. (2010) MicroRNA 128a increases intracellular ROS level by targeting Bmi-1 and inhibits medulloblastoma cancer cell growth by promoting senescence. PLOS ONE 5: e10748. doi:10.1371/journal.pone.0010748. PubMed: 20574517.
    • (2010) PLOS ONE , vol.5
    • Venkataraman, S.1    Alimova, I.2    Fan, R.3    Harris, P.4    Foreman, N.5
  • 31
    • 84856222156 scopus 로고    scopus 로고
    • MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1
    • doi:10.1038/onc.2011.263. PubMed: 21725369
    • Sun L, Yao Y, Liu B, Lin Z, Lin L et al. (2012) MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1. Oncogene 31: 432-445. doi:10.1038/onc.2011.263. PubMed: 21725369.
    • (2012) Oncogene , vol.31 , pp. 432-445
    • Sun, L.1    Yao, Y.2    Liu, B.3    Lin, Z.4    Lin, L.5
  • 32
    • 84873623252 scopus 로고    scopus 로고
    • MicroRNA-218 inhibits cell cycle progression and promotes apoptosis in colon cancer by downregulating BMI1 polycomb ring finger oncogene
    • PubMed: 23255074
    • He X, Dong Y, Wu CW, Zhao Z, Ng SS et al. (2012) MicroRNA-218 inhibits cell cycle progression and promotes apoptosis in colon cancer by downregulating BMI1 polycomb ring finger oncogene. Mol Med 18: 1491-1498. PubMed: 23255074.
    • (2012) Mol Med , vol.18 , pp. 1491-1498
    • He, X.1    Dong, Y.2    Wu, C.W.3    Zhao, Z.4    Ng, S.S.5
  • 33
    • 84861709195 scopus 로고    scopus 로고
    • Attenuation of the beta-catenin/TCF4 complex in colorectal cancer cells induces several growth-suppressive microRNAs that target cancer promoting genes
    • doi:10.1038/onc.2011.453. PubMed: 21963845
    • Schepeler T, Holm A, Halvey P, Nordentoft I, Lamy P et al. (2012) Attenuation of the beta-catenin/TCF4 complex in colorectal cancer cells induces several growth-suppressive microRNAs that target cancer promoting genes. Oncogene 31: 2750-2760. doi:10.1038/onc.2011.453. PubMed: 21963845.
    • (2012) Oncogene , vol.31 , pp. 2750-2760
    • Schepeler, T.1    Holm, A.2    Halvey, P.3    Nordentoft, I.4    Lamy, P.5
  • 34
    • 84855461449 scopus 로고    scopus 로고
    • MicroRNA-30e* promotes human glioma cell invasiveness in an orthotopic xenotransplantation model by disrupting the NF-kappaB/IkappaBalpha negative feedback loop
    • doi:10.1172/JCI58849. PubMed: 22156201
    • Jiang L, Lin C, Song L, Wu J, Chen B et al. (2012) MicroRNA-30e* promotes human glioma cell invasiveness in an orthotopic xenotransplantation model by disrupting the NF-kappaB/IkappaBalpha negative feedback loop. J Clin Invest 122: 33-47. doi:10.1172/JCI58849. PubMed: 22156201.
    • (2012) J Clin Invest , vol.122 , pp. 33-47
    • Jiang, L.1    Lin, C.2    Song, L.3    Wu, J.4    Chen, B.5
  • 35
    • 80054924979 scopus 로고    scopus 로고
    • MicroRNA-451 is involved in the self-renewal, tumorigenicity, and chemoresistance of colorectal cancer stem cells
    • doi:10.1002/stem.741. PubMed: 21948564
    • Bitarte N, Bandres E, Boni V, Zarate R, Rodriguez J et al. (2011) MicroRNA-451 is involved in the self-renewal, tumorigenicity, and chemoresistance of colorectal cancer stem cells. Stem Cells 29: 1661-1671. doi:10.1002/stem.741. PubMed: 21948564.
    • (2011) Stem Cells , vol.29 , pp. 1661-1671
    • Bitarte, N.1    Bandres, E.2    Boni, V.3    Zarate, R.4    Rodriguez, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.