A cell permeable peptide targeting the intracellular loop 2 of endothelin B receptor reduces pulmonary hypertension in a hypoxic rat model

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Green, Daniel S ^a   Rupasinghe, Chamila ^b   Warburton, Rod ^c   Wilson, Jamie L ^a   Sallum, Christine O ^a   Taylor, Linda ^a   Yatawara, Achani ^b   Mierke, Dale ^b   Polgar, Peter ^a   Hill, Nicholas ^c  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Lamont Doherty Earth Observatory   (United States)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PENETRATING PEPTIDE; ENDOTHELIN 1; ENDOTHELIN B RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B;

ANIMAL; ANOXIA; COMPLICATION; DRUG EFFECTS; HYPERTENSION, PULMONARY; INTRACELLULAR SPACE; MALE; METABOLISM; MOLECULARLY TARGETED THERAPY; PATHOLOGY; PATHOPHYSIOLOGY; PULMONARY ARTERY; RAT; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; ANOXIA; CELL-PENETRATING PEPTIDES; ENDOTHELIN-1; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HYPERTENSION, PULMONARY; INTRACELLULAR SPACE; MALE; MOLECULAR TARGETED THERAPY; PROTO-ONCOGENE PROTEINS C-AKT; PULMONARY ARTERY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ENDOTHELIN B; SIGNAL TRANSDUCTION;

EID: 84894248437     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081309     Document Type: Article

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