-
1
-
-
0344874654
-
Esophageal cancer
-
10.1056/NEJMra035010, 14657432
-
Enzinger PC, Mayer RJ. Esophageal cancer. N Engl J Med 2003, 349:2241-2252. 10.1056/NEJMra035010, 14657432.
-
(2003)
N Engl J Med
, vol.349
, pp. 2241-2252
-
-
Enzinger, P.C.1
Mayer, R.J.2
-
2
-
-
28844437366
-
Mcl-1 overexpression in hepatocellular carcinoma: a potential target for antisense therapy
-
10.1016/j.jhep.2005.09.010, 16289418
-
Sieghart W, Losert D, Strommer S, Cejka D, Schmid K, Rasoul-Rockenschaub S, Bodingbauer M, Crevenna R, Monia BP, Peck-Radosavljevic M, Wacheck V. Mcl-1 overexpression in hepatocellular carcinoma: a potential target for antisense therapy. J Hepatol 2006, 44:151-157. 10.1016/j.jhep.2005.09.010, 16289418.
-
(2006)
J Hepatol
, vol.44
, pp. 151-157
-
-
Sieghart, W.1
Losert, D.2
Strommer, S.3
Cejka, D.4
Schmid, K.5
Rasoul-Rockenschaub, S.6
Bodingbauer, M.7
Crevenna, R.8
Monia, B.P.9
Peck-Radosavljevic, M.10
Wacheck, V.11
-
3
-
-
0032928807
-
Immunohistochemical analysis of Bcl-2, Bax, Bcl-X, and Mcl-1 expression in pancreatic cancers
-
10.1159/000011933, 9885381
-
Miyamoto Y, Hosotani R, Wada M, Lee JU, Koshiba T, Fujimoto K, Tsuji S, Nakajima S, Doi R, Kato M, et al. Immunohistochemical analysis of Bcl-2, Bax, Bcl-X, and Mcl-1 expression in pancreatic cancers. Oncology 1999, 56:73-82. 10.1159/000011933, 9885381.
-
(1999)
Oncology
, vol.56
, pp. 73-82
-
-
Miyamoto, Y.1
Hosotani, R.2
Wada, M.3
Lee, J.U.4
Koshiba, T.5
Fujimoto, K.6
Tsuji, S.7
Nakajima, S.8
Doi, R.9
Kato, M.10
-
4
-
-
77953805572
-
Mechanism by which Mcl-1 regulates cancer-specific apoptosis triggered by mda-7/IL-24, an IL-10-related cytokine
-
10.1158/0008-5472.CAN-10-0563, 3171699, 20501829
-
Dash R, Richards JE, Su ZZ, Bhutia SK, Azab B, Rahmani M, Dasmahapatra G, Yacoub A, Dent P, Dmitriev IP, et al. Mechanism by which Mcl-1 regulates cancer-specific apoptosis triggered by mda-7/IL-24, an IL-10-related cytokine. Cancer Res 2010, 70:5034-5045. 10.1158/0008-5472.CAN-10-0563, 3171699, 20501829.
-
(2010)
Cancer Res
, vol.70
, pp. 5034-5045
-
-
Dash, R.1
Richards, J.E.2
Su, Z.Z.3
Bhutia, S.K.4
Azab, B.5
Rahmani, M.6
Dasmahapatra, G.7
Yacoub, A.8
Dent, P.9
Dmitriev, I.P.10
-
5
-
-
73849083434
-
Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival
-
10.1038/nature08646, 20023629
-
Schwickart M, Huang X, Lill JR, Liu J, Ferrando R, French DM, Maecker H, O'Rourke K, Bazan F, Eastham-Anderson J, et al. Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival. Nature 2010, 463:103-107. 10.1038/nature08646, 20023629.
-
(2010)
Nature
, vol.463
, pp. 103-107
-
-
Schwickart, M.1
Huang, X.2
Lill, J.R.3
Liu, J.4
Ferrando, R.5
French, D.M.6
Maecker, H.7
O'Rourke, K.8
Bazan, F.9
Eastham-Anderson, J.10
-
6
-
-
68949099384
-
RNA silencing of Mcl-1 enhances ABT-737-mediated apoptosis in melanoma: role for a caspase-8-dependent pathway
-
10.1371/journal.pone.0006651, 2722728, 19684859
-
Keuling AM, Felton KE, Parker AA, Akbari M, Andrew SE, Tron VA. RNA silencing of Mcl-1 enhances ABT-737-mediated apoptosis in melanoma: role for a caspase-8-dependent pathway. PLoS One 2009, 4:e6651. 10.1371/journal.pone.0006651, 2722728, 19684859.
-
(2009)
PLoS One
, vol.4
-
-
Keuling, A.M.1
Felton, K.E.2
Parker, A.A.3
Akbari, M.4
Andrew, S.E.5
Tron, V.A.6
-
7
-
-
77249119762
-
The landscape of somatic copy-number alteration across human cancers
-
10.1038/nature08822, 2826709, 20164920
-
Beroukhim R, Mermel CH, Porter D, Wei G, Raychaudhuri S, Donovan J, Barretina J, Boehm JS, Dobson J, Urashima M, et al. The landscape of somatic copy-number alteration across human cancers. Nature 2010, 463:899-905. 10.1038/nature08822, 2826709, 20164920.
-
(2010)
Nature
, vol.463
, pp. 899-905
-
-
Beroukhim, R.1
Mermel, C.H.2
Porter, D.3
Wei, G.4
Raychaudhuri, S.5
Donovan, J.6
Barretina, J.7
Boehm, J.S.8
Dobson, J.9
Urashima, M.10
-
8
-
-
79953719297
-
A survey of the anti-apoptotic Bcl-2 subfamily expression in cancer types provides a platform to predict the efficacy of Bcl-2 antagonists in cancer therapy
-
10.1038/cddis.2010.18, 3032312, 21364647
-
Placzek WJ, Wei J, Kitada S, Zhai D, Reed JC, Pellecchia M. A survey of the anti-apoptotic Bcl-2 subfamily expression in cancer types provides a platform to predict the efficacy of Bcl-2 antagonists in cancer therapy. Cell Death Dis 2010, 1:e40. 10.1038/cddis.2010.18, 3032312, 21364647.
-
(2010)
Cell Death Dis
, vol.1
-
-
Placzek, W.J.1
Wei, J.2
Kitada, S.3
Zhai, D.4
Reed, J.C.5
Pellecchia, M.6
-
9
-
-
0034071930
-
Functional analysis of the human MCL-1 gene
-
10.1007/PL00000728, 11130466
-
Akgul C, Turner PC, White MR, Edwards SW. Functional analysis of the human MCL-1 gene. Cell Mol Life Sci 2000, 57:684-691. 10.1007/PL00000728, 11130466.
-
(2000)
Cell Mol Life Sci
, vol.57
, pp. 684-691
-
-
Akgul, C.1
Turner, P.C.2
White, M.R.3
Edwards, S.W.4
-
10
-
-
0032772367
-
The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB
-
84561, 10454566
-
Wang JM, Chao JR, Chen W, Kuo ML, Yen JJ, Yang-Yen HF. The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB. Mol Cell Biol 1999, 19:6195-6206. 84561, 10454566.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 6195-6206
-
-
Wang, J.M.1
Chao, J.R.2
Chen, W.3
Kuo, M.L.4
Yen, J.J.5
Yang-Yen, H.F.6
-
11
-
-
0037902100
-
Serine phosphorylation of STAT3 is essential for Mcl-1 expression and macrophage survival
-
10.1182/blood-2002-11-3396, 12637318
-
Liu H, Ma Y, Cole SM, Zander C, Chen KH, Karras J, Pope RM. Serine phosphorylation of STAT3 is essential for Mcl-1 expression and macrophage survival. Blood 2003, 102:344-352. 10.1182/blood-2002-11-3396, 12637318.
-
(2003)
Blood
, vol.102
, pp. 344-352
-
-
Liu, H.1
Ma, Y.2
Cole, S.M.3
Zander, C.4
Chen, K.H.5
Karras, J.6
Pope, R.M.7
-
12
-
-
0035136846
-
Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression
-
10.1172/JCI9940, 199188, 11160159
-
Epling-Burnette PK, Liu JH, Catlett-Falcone R, Turkson J, Oshiro M, Kothapalli R, Li Y, Wang JM, Yang-Yen HF, Karras J, et al. Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression. J Clin Invest 2001, 107:351-362. 10.1172/JCI9940, 199188, 11160159.
-
(2001)
J Clin Invest
, vol.107
, pp. 351-362
-
-
Epling-Burnette, P.K.1
Liu, J.H.2
Catlett-Falcone, R.3
Turkson, J.4
Oshiro, M.5
Kothapalli, R.6
Li, Y.7
Wang, J.M.8
Yang-Yen, H.F.9
Karras, J.10
-
13
-
-
0033556387
-
Regulation of MCL1 through a serum response factor/Elk-1-mediated mechanism links expression of a viability-promoting member of the BCL2 family to the induction of hematopoietic cell differentiation
-
10.1074/jbc.274.3.1801, 9880563
-
Townsend KJ, Zhou P, Qian L, Bieszczad CK, Lowrey CH, Yen A, Craig RW. Regulation of MCL1 through a serum response factor/Elk-1-mediated mechanism links expression of a viability-promoting member of the BCL2 family to the induction of hematopoietic cell differentiation. J Biol Chem 1999, 274:1801-1813. 10.1074/jbc.274.3.1801, 9880563.
-
(1999)
J Biol Chem
, vol.274
, pp. 1801-1813
-
-
Townsend, K.J.1
Zhou, P.2
Qian, L.3
Bieszczad, C.K.4
Lowrey, C.H.5
Yen, A.6
Craig, R.W.7
-
14
-
-
0037370472
-
Interleukin-3 stimulation of mcl-1 gene transcription involves activation of the PU.1 transcription factor through a p38 mitogen-activated protein kinase-dependent pathway
-
10.1128/MCB.23.6.1896-1909.2003, 149468, 12612065
-
Wang JM, Lai MZ, Yang-Yen HF. Interleukin-3 stimulation of mcl-1 gene transcription involves activation of the PU.1 transcription factor through a p38 mitogen-activated protein kinase-dependent pathway. Mol Cell Biol 2003, 23:1896-1909. 10.1128/MCB.23.6.1896-1909.2003, 149468, 12612065.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 1896-1909
-
-
Wang, J.M.1
Lai, M.Z.2
Yang-Yen, H.F.3
-
15
-
-
76649142741
-
The novel, proteasome-independent NF-kappaB inhibitor V1810 induces apoptosis and cell cycle arrest in multiple myeloma and overcomes NF-kappaB-mediated drug resistance
-
Meinel FG, Mandl-Weber S, Baumann P, Leban J, Schmidmaier R. The novel, proteasome-independent NF-kappaB inhibitor V1810 induces apoptosis and cell cycle arrest in multiple myeloma and overcomes NF-kappaB-mediated drug resistance. Mol Cancer Ther 2010, 9:300-310.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 300-310
-
-
Meinel, F.G.1
Mandl-Weber, S.2
Baumann, P.3
Leban, J.4
Schmidmaier, R.5
-
16
-
-
78649305848
-
Thiocolchicoside exhibits anticancer effects through downregulation of NF-kappaB pathway and its regulated gene products linked to inflammation and cancer
-
10.1158/1940-6207.CAPR-10-0037, 3142676, 20978115
-
Reuter S, Prasad S, Phromnoi K, Ravindran J, Sung B, Yadav VR, Kannappan R, Chaturvedi MM, Aggarwal BB. Thiocolchicoside exhibits anticancer effects through downregulation of NF-kappaB pathway and its regulated gene products linked to inflammation and cancer. Cancer Prev Res (Phila) 2010, 3:1462-1472. 10.1158/1940-6207.CAPR-10-0037, 3142676, 20978115.
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, pp. 1462-1472
-
-
Reuter, S.1
Prasad, S.2
Phromnoi, K.3
Ravindran, J.4
Sung, B.5
Yadav, V.R.6
Kannappan, R.7
Chaturvedi, M.M.8
Aggarwal, B.B.9
-
17
-
-
34347246278
-
Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death
-
10.1016/j.ccr.2007.05.006, 17613437
-
Ricci MS, Kim SH, Ogi K, Plastaras JP, Ling J, Wang W, Jin Z, Liu YY, Dicker DT, Chiao PJ, et al. Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death. Cancer Cell 2007, 12:66-80. 10.1016/j.ccr.2007.05.006, 17613437.
-
(2007)
Cancer Cell
, vol.12
, pp. 66-80
-
-
Ricci, M.S.1
Kim, S.H.2
Ogi, K.3
Plastaras, J.P.4
Ling, J.5
Wang, W.6
Jin, Z.7
Liu, Y.Y.8
Dicker, D.T.9
Chiao, P.J.10
-
18
-
-
84864294419
-
N-alpha-acetyltransferase 10 protein inhibits apoptosis through RelA/p65-regulated MCL1 expression
-
10.1093/carcin/bgs144, 22496479
-
Xu H, Jiang B, Meng L, Ren T, Zeng Y, Wu J, Qu L, Shou C. N-alpha-acetyltransferase 10 protein inhibits apoptosis through RelA/p65-regulated MCL1 expression. Carcinogenesis 2012, 33:1193-1202. 10.1093/carcin/bgs144, 22496479.
-
(2012)
Carcinogenesis
, vol.33
, pp. 1193-1202
-
-
Xu, H.1
Jiang, B.2
Meng, L.3
Ren, T.4
Zeng, Y.5
Wu, J.6
Qu, L.7
Shou, C.8
-
19
-
-
33845768987
-
Integrating cell-signalling pathways with NF-kappaB and IKK function
-
10.1038/nrm2083, 17183360
-
Perkins ND. Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat Rev Mol Cell Biol 2007, 8:49-62. 10.1038/nrm2083, 17183360.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 49-62
-
-
Perkins, N.D.1
-
20
-
-
10644239087
-
Regulation of NF-kappaB by atypical activators and tumour suppressors
-
Perkins ND. Regulation of NF-kappaB by atypical activators and tumour suppressors. Biochem Soc Trans 2004, 32:936-939.
-
(2004)
Biochem Soc Trans
, vol.32
, pp. 936-939
-
-
Perkins, N.D.1
-
21
-
-
37549004392
-
Nuclear factor-kappaB activation: from bench to bedside
-
10.3181/0707-MR-196, 18156302
-
Sethi G, Sung B, Aggarwal BB. Nuclear factor-kappaB activation: from bench to bedside. Exp Biol Med (Maywood) 2008, 233:21-31. 10.3181/0707-MR-196, 18156302.
-
(2008)
Exp Biol Med (Maywood)
, vol.233
, pp. 21-31
-
-
Sethi, G.1
Sung, B.2
Aggarwal, B.B.3
-
22
-
-
33750432183
-
Nuclear factor-kappaB and inhibitor of kappaB kinase pathways in oncogenic initiation and progression
-
10.1038/sj.onc.1209942, 17072330
-
Basseres DS, Baldwin AS. Nuclear factor-kappaB and inhibitor of kappaB kinase pathways in oncogenic initiation and progression. Oncogene 2006, 25:6817-6830. 10.1038/sj.onc.1209942, 17072330.
-
(2006)
Oncogene
, vol.25
, pp. 6817-6830
-
-
Basseres, D.S.1
Baldwin, A.S.2
-
23
-
-
33644853585
-
Association of activated transcription factor nuclear factor kappab with chemoradiation resistance and poor outcome in esophageal carcinoma
-
10.1200/JCO.2005.03.8810, 16401681
-
Izzo JG, Malhotra U, Wu TT, Ensor J, Luthra R, Lee JH, Swisher SG, Liao Z, Chao KS, Hittelman WN, et al. Association of activated transcription factor nuclear factor kappab with chemoradiation resistance and poor outcome in esophageal carcinoma. J Clin Oncol 2006, 24:748-754. 10.1200/JCO.2005.03.8810, 16401681.
-
(2006)
J Clin Oncol
, vol.24
, pp. 748-754
-
-
Izzo, J.G.1
Malhotra, U.2
Wu, T.T.3
Ensor, J.4
Luthra, R.5
Lee, J.H.6
Swisher, S.G.7
Liao, Z.8
Chao, K.S.9
Hittelman, W.N.10
-
24
-
-
33646723047
-
Nuclear factor-kB signaling pathway constitutively activated in esophageal squamous cell carcinoma cell lines and inhibition of growth of cells by small interfering RNA
-
10.1111/j.1745-7270.2006.00166.x, 16680372
-
Tian F, Zang WD, Hou WH, Liu HT, Xue LX. Nuclear factor-kB signaling pathway constitutively activated in esophageal squamous cell carcinoma cell lines and inhibition of growth of cells by small interfering RNA. Acta Biochim Biophys Sin (Shanghai) 2006, 38:318-326. 10.1111/j.1745-7270.2006.00166.x, 16680372.
-
(2006)
Acta Biochim Biophys Sin (Shanghai)
, vol.38
, pp. 318-326
-
-
Tian, F.1
Zang, W.D.2
Hou, W.H.3
Liu, H.T.4
Xue, L.X.5
-
25
-
-
0034704939
-
Epidermal growth factor (EGF) suppresses staurosporine-induced apoptosis by inducing mcl-1 via the mitogen-activated protein kinase pathway
-
10.1038/sj.onc.1203452, 10763823
-
Leu CM, Chang C, Hu C. Epidermal growth factor (EGF) suppresses staurosporine-induced apoptosis by inducing mcl-1 via the mitogen-activated protein kinase pathway. Oncogene 2000, 19:1665-1675. 10.1038/sj.onc.1203452, 10763823.
-
(2000)
Oncogene
, vol.19
, pp. 1665-1675
-
-
Leu, C.M.1
Chang, C.2
Hu, C.3
-
26
-
-
58149294015
-
Overexpression of PLK1 is associated with poor survival by inhibiting apoptosis via enhancement of survivin level in esophageal squamous cell carcinoma
-
10.1002/ijc.23990, 19004025
-
Feng YB, Lin DC, Shi ZZ, Wang XC, Shen XM, Zhang Y, Du XL, Luo ML, Xu X, Han YL, et al. Overexpression of PLK1 is associated with poor survival by inhibiting apoptosis via enhancement of survivin level in esophageal squamous cell carcinoma. Int J Cancer 2009, 124:578-588. 10.1002/ijc.23990, 19004025.
-
(2009)
Int J Cancer
, vol.124
, pp. 578-588
-
-
Feng, Y.B.1
Lin, D.C.2
Shi, Z.Z.3
Wang, X.C.4
Shen, X.M.5
Zhang, Y.6
Du, X.L.7
Luo, M.L.8
Xu, X.9
Han, Y.L.10
-
27
-
-
0023852747
-
Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line
-
10.1083/jcb.106.3.761, 2115116, 2450098
-
Boukamp P, Petrussevska RT, Breitkreutz D, Hornung J, Markham A, Fusenig NE. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J Cell Biol 1988, 106:761-771. 10.1083/jcb.106.3.761, 2115116, 2450098.
-
(1988)
J Cell Biol
, vol.106
, pp. 761-771
-
-
Boukamp, P.1
Petrussevska, R.T.2
Breitkreutz, D.3
Hornung, J.4
Markham, A.5
Fusenig, N.E.6
-
28
-
-
33846960757
-
HTERT/re-caspase-3 system induce apoptosis in hTERT-positive cancer cells
-
10.4161/cbt.5.11.3460, 17172814
-
Yang LF, Zhao Y, Zeng L, Gong JP, Cao Y. hTERT/re-caspase-3 system induce apoptosis in hTERT-positive cancer cells. Cancer Biol Ther 2006, 5:1546-1553. 10.4161/cbt.5.11.3460, 17172814.
-
(2006)
Cancer Biol Ther
, vol.5
, pp. 1546-1553
-
-
Yang, L.F.1
Zhao, Y.2
Zeng, L.3
Gong, J.P.4
Cao, Y.5
-
29
-
-
33845735954
-
Upregulated expression of kappa light chain by Epstein-Barr virus encoded latent membrane protein 1 in nasopharyngeal carcinoma cells via NF-kappaB and AP-1 pathways
-
10.1016/j.cellsig.2006.07.012, 16979873
-
Liu HD, Zheng H, Li M, Hu DS, Tang M, Cao Y. Upregulated expression of kappa light chain by Epstein-Barr virus encoded latent membrane protein 1 in nasopharyngeal carcinoma cells via NF-kappaB and AP-1 pathways. Cell Signal 2007, 19:419-427. 10.1016/j.cellsig.2006.07.012, 16979873.
-
(2007)
Cell Signal
, vol.19
, pp. 419-427
-
-
Liu, H.D.1
Zheng, H.2
Li, M.3
Hu, D.S.4
Tang, M.5
Cao, Y.6
-
30
-
-
71149121322
-
LMP1-augmented kappa intron enhancer activity contributes to upregulation expression of Ig kappa light chain via NF-kappaB and AP-1 pathways in nasopharyngeal carcinoma cells
-
10.1186/1476-4598-8-92, 2774294, 19860880
-
Liu H, Zheng H, Duan Z, Hu D, Li M, Liu S, Li Z, Deng X, Wang Z, Tang M, et al. LMP1-augmented kappa intron enhancer activity contributes to upregulation expression of Ig kappa light chain via NF-kappaB and AP-1 pathways in nasopharyngeal carcinoma cells. Mol Cancer 2009, 8:92. 10.1186/1476-4598-8-92, 2774294, 19860880.
-
(2009)
Mol Cancer
, vol.8
, pp. 92
-
-
Liu, H.1
Zheng, H.2
Duan, Z.3
Hu, D.4
Li, M.5
Liu, S.6
Li, Z.7
Deng, X.8
Wang, Z.9
Tang, M.10
-
31
-
-
56749156112
-
Epstein-Barr virus latent membrane protein 1 mediates serine 25 phosphorylation and nuclear entry of annexin A2 via PI-PLC-PKCalpha/PKCbeta pathway
-
10.1002/mc.20445, 18412141
-
Luo W, Yan G, Li L, Wang Z, Liu H, Zhou S, Liu S, Tang M, Yi W, Dong Z, Cao Y. Epstein-Barr virus latent membrane protein 1 mediates serine 25 phosphorylation and nuclear entry of annexin A2 via PI-PLC-PKCalpha/PKCbeta pathway. Mol Carcinog 2008, 47:934-946. 10.1002/mc.20445, 18412141.
-
(2008)
Mol Carcinog
, vol.47
, pp. 934-946
-
-
Luo, W.1
Yan, G.2
Li, L.3
Wang, Z.4
Liu, H.5
Zhou, S.6
Liu, S.7
Tang, M.8
Yi, W.9
Dong, Z.10
Cao, Y.11
-
32
-
-
84863236801
-
EBV-encoded LMP1 upregulates Igkappa 3′enhancer activity and Igkappa expression in nasopharyngeal cancer cells by activating the Ets-1 through ERKs signaling
-
10.1371/journal.pone.0032624, 3291551, 22396784
-
Liu H, Duan Z, Zheng H, Hu D, Li M, Tao Y, Bode AM, Dong Z, Cao Y. EBV-encoded LMP1 upregulates Igkappa 3′enhancer activity and Igkappa expression in nasopharyngeal cancer cells by activating the Ets-1 through ERKs signaling. PLoS One 2012, 7:e32624. 10.1371/journal.pone.0032624, 3291551, 22396784.
-
(2012)
PLoS One
, vol.7
-
-
Liu, H.1
Duan, Z.2
Zheng, H.3
Hu, D.4
Li, M.5
Tao, Y.6
Bode, A.M.7
Dong, Z.8
Cao, Y.9
-
33
-
-
33847367725
-
Mechanism and functional role of XIAP and Mcl-1 down-regulation in flavopiridol/vorinostat antileukemic interactions
-
10.1158/1535-7163.MCT-06-0562, 17308065
-
Rosato RR, Almenara JA, Kolla SS, Maggio SC, Coe S, Gimenez MS, Dent P, Grant S. Mechanism and functional role of XIAP and Mcl-1 down-regulation in flavopiridol/vorinostat antileukemic interactions. Mol Cancer Ther 2007, 6:692-702. 10.1158/1535-7163.MCT-06-0562, 17308065.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 692-702
-
-
Rosato, R.R.1
Almenara, J.A.2
Kolla, S.S.3
Maggio, S.C.4
Coe, S.5
Gimenez, M.S.6
Dent, P.7
Grant, S.8
-
34
-
-
48049121067
-
E-cadherin controls beta-catenin and NF-kappaB transcriptional activity in mesenchymal gene expression
-
10.1242/jcs.021667, 18565826
-
Solanas G, Porta-de-la-Riva M, Agusti C, Casagolda D, Sanchez-Aguilera F, Larriba MJ, Pons F, Peiro S, Escriva M, Munoz A, et al. E-cadherin controls beta-catenin and NF-kappaB transcriptional activity in mesenchymal gene expression. J Cell Sci 2008, 121:2224-2234. 10.1242/jcs.021667, 18565826.
-
(2008)
J Cell Sci
, vol.121
, pp. 2224-2234
-
-
Solanas, G.1
Porta-de-la-Riva, M.2
Agusti, C.3
Casagolda, D.4
Sanchez-Aguilera, F.5
Larriba, M.J.6
Pons, F.7
Peiro, S.8
Escriva, M.9
Munoz, A.10
-
35
-
-
10644224272
-
Induction of the RelB NF-kappaB subunit by the cytomegalovirus IE1 protein is mediated via Jun kinase and c-Jun/Fra-2 AP-1 complexes
-
10.1128/JVI.79.1.95-105.2005, 538727, 15596805
-
Wang X, Sonenshein GE. Induction of the RelB NF-kappaB subunit by the cytomegalovirus IE1 protein is mediated via Jun kinase and c-Jun/Fra-2 AP-1 complexes. J Virol 2005, 79:95-105. 10.1128/JVI.79.1.95-105.2005, 538727, 15596805.
-
(2005)
J Virol
, vol.79
, pp. 95-105
-
-
Wang, X.1
Sonenshein, G.E.2
-
36
-
-
64949182097
-
Overexpression of Cap43 is associated with malignant status of esophageal cancer
-
Sohda M, Mochida Y, Kato H, Miyazaki T, Nakajima M, Fukuchi M, Manda R, Fukai Y, Masuda N, Ono M, et al. Overexpression of Cap43 is associated with malignant status of esophageal cancer. Anticancer Res 2009, 29:965-970.
-
(2009)
Anticancer Res
, vol.29
, pp. 965-970
-
-
Sohda, M.1
Mochida, Y.2
Kato, H.3
Miyazaki, T.4
Nakajima, M.5
Fukuchi, M.6
Manda, R.7
Fukai, Y.8
Masuda, N.9
Ono, M.10
-
37
-
-
53249127054
-
Beta-Catenin/TCF pathway upregulates STAT3 expression in human esophageal squamous cell carcinoma
-
10.1016/j.canlet.2008.05.035, 18602747
-
Yan S, Zhou C, Zhang W, Zhang G, Zhao X, Yang S, Wang Y, Lu N, Zhu H, Xu N. beta-Catenin/TCF pathway upregulates STAT3 expression in human esophageal squamous cell carcinoma. Cancer Lett 2008, 271:85-97. 10.1016/j.canlet.2008.05.035, 18602747.
-
(2008)
Cancer Lett
, vol.271
, pp. 85-97
-
-
Yan, S.1
Zhou, C.2
Zhang, W.3
Zhang, G.4
Zhao, X.5
Yang, S.6
Wang, Y.7
Lu, N.8
Zhu, H.9
Xu, N.10
-
38
-
-
55549140173
-
Role of the histone H3 lysine 4 methyltransferase, SET7/9, in the regulation of NF-kappaB-dependent inflammatory genes. Relevance to diabetes and inflammation
-
10.1074/jbc.M802800200, 2546554, 18650421
-
Li Y, Reddy MA, Miao F, Shanmugam N, Yee JK, Hawkins D, Ren B, Natarajan R. Role of the histone H3 lysine 4 methyltransferase, SET7/9, in the regulation of NF-kappaB-dependent inflammatory genes. Relevance to diabetes and inflammation. J Biol Chem 2008, 283:26771-26781. 10.1074/jbc.M802800200, 2546554, 18650421.
-
(2008)
J Biol Chem
, vol.283
, pp. 26771-26781
-
-
Li, Y.1
Reddy, M.A.2
Miao, F.3
Shanmugam, N.4
Yee, J.K.5
Hawkins, D.6
Ren, B.7
Natarajan, R.8
-
39
-
-
33646024035
-
A novel NF-kappaB binding site controls human granzyme B gene transcription
-
Huang C, Bi E, Hu Y, Deng W, Tian Z, Dong C, Hu Y, Sun B. A novel NF-kappaB binding site controls human granzyme B gene transcription. J Immunol 2006, 176:4173-4181.
-
(2006)
J Immunol
, vol.176
, pp. 4173-4181
-
-
Huang, C.1
Bi, E.2
Hu, Y.3
Deng, W.4
Tian, Z.5
Dong, C.6
Hu, Y.7
Sun, B.8
-
40
-
-
9644273898
-
Targeting promiscuous signaling pathways in cancer: another Notch in the bedpost
-
10.1016/j.molmed.2004.10.001, 15567329
-
Beverly LJ, Capobianco AJ. Targeting promiscuous signaling pathways in cancer: another Notch in the bedpost. Trends Mol Med 2004, 10:591-598. 10.1016/j.molmed.2004.10.001, 15567329.
-
(2004)
Trends Mol Med
, vol.10
, pp. 591-598
-
-
Beverly, L.J.1
Capobianco, A.J.2
-
41
-
-
21244472965
-
Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis
-
10.1016/j.cell.2005.06.009, 15989957
-
Zhong Q, Gao W, Du F, Wang X. Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis. Cell 2005, 121:1085-1095. 10.1016/j.cell.2005.06.009, 15989957.
-
(2005)
Cell
, vol.121
, pp. 1085-1095
-
-
Zhong, Q.1
Gao, W.2
Du, F.3
Wang, X.4
-
42
-
-
34347350211
-
Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization
-
10.1128/MCB.00620-06, 1900029, 17387146
-
Ding Q, He X, Hsu JM, Xia W, Chen CT, Li LY, Lee DF, Liu JC, Zhong Q, Wang X, Hung MC. Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization. Mol Cell Biol 2007, 27:4006-4017. 10.1128/MCB.00620-06, 1900029, 17387146.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 4006-4017
-
-
Ding, Q.1
He, X.2
Hsu, J.M.3
Xia, W.4
Chen, C.T.5
Li, L.Y.6
Lee, D.F.7
Liu, J.C.8
Zhong, Q.9
Wang, X.10
Hung, M.C.11
-
43
-
-
79952271269
-
Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7
-
10.1038/nature09779, 21368834
-
Wertz IE, Kusam S, Lam C, Okamoto T, Sandoval W, Anderson DJ, Helgason E, Ernst JA, Eby M, Liu J, et al. Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7. Nature 2011, 471:110-114. 10.1038/nature09779, 21368834.
-
(2011)
Nature
, vol.471
, pp. 110-114
-
-
Wertz, I.E.1
Kusam, S.2
Lam, C.3
Okamoto, T.4
Sandoval, W.5
Anderson, D.J.6
Helgason, E.7
Ernst, J.A.8
Eby, M.9
Liu, J.10
-
44
-
-
34548687035
-
Mir-29 regulates Mcl-1 protein expression and apoptosis
-
10.1038/sj.onc.1210436, 2432524, 17404574
-
Mott JL, Kobayashi S, Bronk SF, Gores GJ. mir-29 regulates Mcl-1 protein expression and apoptosis. Oncogene 2007, 26:6133-6140. 10.1038/sj.onc.1210436, 2432524, 17404574.
-
(2007)
Oncogene
, vol.26
, pp. 6133-6140
-
-
Mott, J.L.1
Kobayashi, S.2
Bronk, S.F.3
Gores, G.J.4
-
45
-
-
79956017530
-
Targeting aberrant PI3K/Akt activation by PI103 restores sensitivity to TRAIL-induced apoptosis in neuroblastoma
-
10.1158/1078-0432.CCR-10-2530, 21355080
-
Opel D, Naumann I, Schneider M, Bertele D, Debatin KM, Fulda S. Targeting aberrant PI3K/Akt activation by PI103 restores sensitivity to TRAIL-induced apoptosis in neuroblastoma. Clin Cancer Res 2011, 17:3233-3247. 10.1158/1078-0432.CCR-10-2530, 21355080.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 3233-3247
-
-
Opel, D.1
Naumann, I.2
Schneider, M.3
Bertele, D.4
Debatin, K.M.5
Fulda, S.6
-
46
-
-
34548096400
-
Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1
-
10.1158/1078-0432.CCR-07-0665, 17652623
-
Wang YF, Jiang CC, Kiejda KA, Gillespie S, Zhang XD, Hersey P. Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1. Clin Cancer Res 2007, 13:4934-4942. 10.1158/1078-0432.CCR-07-0665, 17652623.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4934-4942
-
-
Wang, Y.F.1
Jiang, C.C.2
Kiejda, K.A.3
Gillespie, S.4
Zhang, X.D.5
Hersey, P.6
-
47
-
-
0037062442
-
Quantitative prediction of NF-kappa B DNA-protein interactions
-
10.1073/pnas.102674699, 123039, 12048232
-
Udalova IA, Mott R, Field D, Kwiatkowski D. Quantitative prediction of NF-kappa B DNA-protein interactions. Proc Natl Acad Sci U S A 2002, 99:8167-8172. 10.1073/pnas.102674699, 123039, 12048232.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 8167-8172
-
-
Udalova, I.A.1
Mott, R.2
Field, D.3
Kwiatkowski, D.4
-
48
-
-
0142105387
-
Genetic analysis of NF-kappaB/Rel transcription factors defines functional specificities
-
10.1093/emboj/cdg534, 213788, 14532125
-
Hoffmann A, Leung TH, Baltimore D. Genetic analysis of NF-kappaB/Rel transcription factors defines functional specificities. Embo J 2003, 22:5530-5539. 10.1093/emboj/cdg534, 213788, 14532125.
-
(2003)
Embo J
, vol.22
, pp. 5530-5539
-
-
Hoffmann, A.1
Leung, T.H.2
Baltimore, D.3
-
49
-
-
18244379306
-
Interactions of NF-kappaB with chromatin: the art of being at the right place at the right time
-
Natoli G, Saccani S, Bosisio D, Marazzi I. Interactions of NF-kappaB with chromatin: the art of being at the right place at the right time. Nat Immunol 2005, 6:439-445.
-
(2005)
Nat Immunol
, vol.6
, pp. 439-445
-
-
Natoli, G.1
Saccani, S.2
Bosisio, D.3
Marazzi, I.4
-
50
-
-
0038771214
-
Modulation of NF-kappaB activity by exchange of dimers
-
10.1016/S1097-2765(03)00227-2, 12820969
-
Saccani S, Pantano S, Natoli G. Modulation of NF-kappaB activity by exchange of dimers. Mol Cell 2003, 11:1563-1574. 10.1016/S1097-2765(03)00227-2, 12820969.
-
(2003)
Mol Cell
, vol.11
, pp. 1563-1574
-
-
Saccani, S.1
Pantano, S.2
Natoli, G.3
-
51
-
-
0027384590
-
NF-kappa B subunit-specific regulation of the interleukin-8 promoter
-
364673, 8413215
-
Kunsch C, Rosen CA. NF-kappa B subunit-specific regulation of the interleukin-8 promoter. Mol Cell Biol 1993, 13:6137-6146. 364673, 8413215.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 6137-6146
-
-
Kunsch, C.1
Rosen, C.A.2
-
52
-
-
2442454735
-
Prognostic significance of a short sequence insertion in the MCL-1 promoter in chronic lymphocytic leukemia
-
10.1093/jnci/djh122, 15126604
-
Moshynska O, Sankaran K, Pahwa P, Saxena A. Prognostic significance of a short sequence insertion in the MCL-1 promoter in chronic lymphocytic leukemia. J Natl Cancer Inst 2004, 96:673-682. 10.1093/jnci/djh122, 15126604.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 673-682
-
-
Moshynska, O.1
Sankaran, K.2
Pahwa, P.3
Saxena, A.4
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