Fundamental determinants of protein requirements in the ICU

Current Opinion in Clinical Nutrition and Metabolic Care

Volumn 17, Issue 2, 2014, Pages 183-189

  Weijs, Peter J M ^a,b  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b AMSTERDAM UNIVERSITY OF APPLIED SCIENCES   (Netherlands)

Author keywords

Critically ill; Muscle mass; Protein dosing; Protein needs

Indexed keywords

CRITICAL ILLNESS; DIETARY PROTEINS; ENERGY INTAKE; FEMALE; HUMANS; INTENSIVE CARE; INTENSIVE CARE UNITS; MALE; MUSCLE, SKELETAL; NUTRITIONAL REQUIREMENTS; PROTEIN-ENERGY MALNUTRITION; SEPSIS;

EID: 84894171116     PISSN: 13631950     EISSN: 14736519     Source Type: Journal    
DOI: 10.1097/MCO.0000000000000029     Document Type: Review

References (44)

1. Sion-Sarid R, Cohen J, Houri Z, Singer P. Indirect calorimetry: a guide for optimizing nutritional support in the critically ill child. Nutrition 2013; 29:1094-1099.
2. Kreymann KG, Berger MM, Deutz NE, et al. ESPEN Guidelines on enteral nutrition: intensive care. Clin Nutr 2006; 25:210-223.
3. Singer P, Berger MM, Van den Berghe G, et al. ESPEN Guidelines on parenteral nutrition: intensive care. Clin Nutr 2009; 28:387-400.
4. McClave SA, Martindale RG, Vanek VW, et al. Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). JPEN J Parenter Enteral Nutr 2009; 33:277-316.
5. Joint WHO/FAO/UNU Expert Consultation. Protein and amino acid requirements in human nutrition. World Health Organ Tech Rep Ser 2007; 1-265.
6. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). Scientific opinion on dietary reference values for protein. EFSA J 2012; 10:. 2557 (1-66).
7. Millward DJ. Identifying recommended dietary allowances for protein and amino acids: a critique of the 2007WHO/FAO/UNU report. Br J Nutr 2012; 108 (Suppl 2):S3-S21.
8. Dardevet D, Rémond D, Peyron MA, et al. Muscle wasting and resistance of muscle anabolism: the 'anabolic threshold concept' for adapted nutritional strategies during sarcopenia. Sci World J 2012; 2012:269531.
9. Berg A, Rooyackers O, Bellander BM, Wernerman J. Whole body protein kinetics during hypocaloric and normocaloric feeding in critically ill patients. Crit Care 2013; 17:R158.
10. Herridge MS, Tansey CM, MatteA, et al. Cheung AM; Canadian Critical Care Trials Group. Functional disability 5 years after acute respiratory distress syndrome. N Engl J Med 2011; 364:1293-1304.
11. Wischmeyer PE. The evolution of nutrition in critical care: how much, how soon? Crit Care 2013; 17 (Suppl 1):S7.
12. Alberda C, Gramlich L, Jones N, et al. The relationship between nutritional intake and clinical outcomes in critically ill patients: results of an international multicenter observational study. Intensive Care Med 2009; 35:1728-1737.
13. Carli F, Webster J, Ramachandra V, et al. Aspects of protein metabolism after elective surgery in patients receiving constant nutritional support. Clin Sci (Lond) 1990; 78:621-628.
14. Ishibashi N, Plank LD, Sando K, Hill GL. Optimal protein requirements during the first 2 weeks after the onset of critical illness. Crit Care Med 1998; 26:1529-1535.
15. Larsson J, Lennmarken C, Martensson J, et al. Nitrogen requirements in severely injured patients. Br J Surg 1990; 77:413-416.
16. Masiero E, Agatea L, Mammucari C, et al. Autophagy is required to maintain muscle mass. Cell Metab 2009; 10:507-515.
17. Vanhorebeek I, Gunst J, Derde S, et al. Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients. J Clin Endocrinol Metab 2011; 96:E633-E645.
18. Derde S, Vanhorebeek I, Gü iza F, et al. Early parenteral nutrition evokes a phenotype of autophagy deficiency in liver and skeletal muscle of critically ill rabbits. Endocrinology 2012; 153:2267-2276.
19. Lopez Hell?́n J, Baena-Fustegueras JA, Sab?́n-Urk?́a P, et al. Nutritional modulation of protein metabolism after gastrointestinal surgery. Eur J Clin Nutr 2008; 62:254-262.
20. Klaude M, Mori M, Tjä der I, et al. Protein metabolism and gene expression in skeletal muscle of critically ill patients with sepsis. Clin Sci (Lond) 2012; 122:133-142.
21. Hoffer LJ, Bistrian BR. Appropriate protein provision in critical illness: a systematic and narrative review. Am J Clin Nutr 2012; 96:591-600.
22. Weijs PJ, Wischmeyer PE. Optimizing energy and protein balance in the ICU. Curr Opin Clin Nutr Metab Care 2013; 16:194-201.
23. Volpi E, Campbell WW, Dwyer JT, et al. Is the optimal level of protein intake for older adults greater than the recommended dietary allowance? J Gerontol A Biol Sci Med Sci 2013; 68:677-681.
24. Symons TB, Sheffield-Moore M, Wolfe RR, Paddon-Jones D. A moderate serving of high-quality protein maximally stimulates skeletal muscle protein synthesis in young and elderly subjects. J Am Diet Assoc 2009; 109:1582-1586.
25. Verreijen AM, Engberink MF, Verlaan S, Weijs PJ. Exploration of what level of protein is needed for muscle mass accretion during weight loss with resistance training in obese elderly. Clin Nutr 2013; 32:S8.
26. Heidegger CP, Berger MM, Graf S, et al. Optimisation of energy provision with supplemental parenteral nutrition in critically ill patients: a randomised controlled clinical trial. Lancet 2013; 381:385-393.
27. Singer P, Anbar R, Cohen J, et al. The tight calorie control study (TICACOS): a prospective, randomized, controlled pilot study of nutritional support in critically ill patients. Intensive Care Med 2011; 37:601-609.
28. Casaer MP, Wilmer A, Van den Berghe G. Supplemental parenteral nutrition in critically ill patients. Lancet 2013; 381:1715.
29. Casaer MP, Mesotten D, Hermans G, et al. Early versus late parenteral nutrition in critically ill adults. N Engl J Med 2011; 365:506-517.
30. Vincent JL, Preiser JC. When should we add parenteral to enteral nutrition? Lancet 2013; 381:354-355.
31. Weijs PJ, Sauerwein HP, Kondrup J. Protein recommendations in the ICU: g protein/kg body weight-which body weight for underweight and obese patients? Clin Nutr 2012; 31:774-775.
32. Moisey LL, Mourtzakis M, Cotton BA, et al. Skeletal muscle predicts ventilatorfree days, ICU-free days, and mortality in elderly ICU patients. Crit Care 2013; 17:R206.
33. Weijs PJM, Looijaard WGPM, Dekker IM, et al. Low skeletal muscle area is a risk factor for mortality in mechanically ventilated critically ill patients. Crit Care 2013; 18:R12.
34. Casaer MP, Langouche L, Coudyzer W, et al. Impact of early parenteral nutrition on muscle and adipose tissue compartments during critical illness. Crit Care Med 2013; 41:2298-2309.
35. Weijs PJ, Kruizenga HM, van Dijk AE, et al. Validation of predictive equations for resting energy expenditure in adult outpatients and inpatients. Clin Nutr 2008; 27:150-157.
36. Casaer MP, Wilmer A, Hermans G, et al. Role of disease and macronutrient dose in the randomized controlled EPaNIC trial: a post hoc analysis. Am J Respir Crit Care Med 2013; 187:247-255.
37. Puthucheary ZA, Rawal J, McPhail M, et al. Acute skeletal muscle wasting in critical illness. JAMA 2013; 310:1591-1600.
38. Strack van Schijndel RJ, Weijs PJ, Koopmans RH, et al. Optimal nutrition during the period of mechanical ventilation decreases mortality in critically ill, long-term acute female patients: a prospective observational cohort study. Crit Care 2009; 13:R132.
39. Weijs PJ, Stapel SN, de Groot SD, et al. Optimal protein and energy nutrition decreases mortality in mechanically ventilated, critically ill patients: a prospective observational cohort study. JPEN J Parenter Enteral Nutr 2012; 36:60-68.
40. Doig GS, Simpson F, Sweetman EA, et al. Early PN Investigators of the ANZICS Clinical Trials Group. Early parenteral nutrition in critically ill patients with short-term relative contraindications to early enteral nutrition: a randomized controlled trial. JAMA 2013; 309:2130-2138.
41. Braunschweig CA, Sheean PM, Peterson SJ, et al. Exploitation of diagnostic computed tomography scans to assess the impact of nutritional support on body composition changes in respiratory failure patients. JPEN J Parenter Enteral Nutr 2013. [Epub ahead of print]
42. Strack van Schijndel RJM, Weijs PJM, Sauerwein HP, et al. An algorithm for balanced protein/energy provision in critically ill mechanically ventilated patients. E-spen Eur E-J Clin Nutr Metabolism 2007; 2:69-74.
43. Strack van Schijndel RJ, de Groot SD, Driessen RH, et al. Computer-aided support improves early and adequate delivery of nutrients in the ICU. Neth J Med 2009; 67:388-393.
44. Allingstrup MJ, Esmailzadeh N, Wilkens Knudsen A, et al. Provision of protein and energy in relation to measured requirements in intensive care patients. Clin Nutr 2012; 31:462-468.