Brain-derived neurotrophic factor, but not body weight, correlated with a reduction in depression scale scores in men with metabolic syndrome: A prospective weight-reduction study

Diabetology and Metabolic Syndrome

Volumn 6, Issue 1, 2014, Pages

  Lee, I Te ^a,b,c   Fu, Chia Po ^a   Lee, Wen Jane ^a   Liang, Kae Woei ^a,c   Lin, Shih Yi ^a,c   Wan, Chu Jen ^d   Sheu, Wayne Huey Herng ^a,b,c,e  

^a TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d HUNGKUANG UNIVERSITY   (Taiwan)

^e NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

Exercise; Lifestyle intervention; Obesity; Zung self rating depression scale

Indexed keywords

EID: 84894106157     PISSN: None     EISSN: 17585996     Source Type: Journal    
DOI: 10.1186/1758-5996-6-18     Document Type: Article

References (62)

1. Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). National Cholesterol Education Program, JAMA 2001 285 19 2486 2497 10.1001/jama.285.19. 2486 11368702
2. Metabolic syndrome with and without C-reactive protein as a predictor of coronary heart disease and diabetes in the West of Scotland Coronary Prevention Study. Sattar N, Gaw A, Scherbakova O, Ford I, O'Reilly DS, Haffner SM, Isles C, Macfarlane PW, Packard CJ, Cobbe SM, et al. Circulation 2003 108 4 414 419 10.1161/01.CIR.0000080897.52664.94 12860911 (Pubitemid 36935533)
3. The metabolic syndrome. Cornier MA, Dabelea D, Hernandez TL, Lindstrom RC, Steig AJ, Stob NR, Van Pelt RE, Wang H, Eckel RH, Endocrine reviews 2008 29 7 777 822 10.1210/er.2008-0024 18971485
4. The metabolic syndrome: a global public health problem and a new definition. Zimmet P, Magliano D, Matsuzawa Y, Alberti G, Shaw J, J Atherosclerosis Thromb 2005 12 6 295 300 10.5551/jat.12.295
5. Abdominal obesity and metabolic syndrome. Despres JP, Lemieux I, Nature 2006 444 7121 881 887 10.1038/nature05488 17167477 (Pubitemid 46024995)
6. The association of low-grade inflammation, urinary albumin, and insulin resistance with metabolic syndrome in nondiabetic Taiwanese. Lee IT, Lee WJ, Huang CN, WHHS, Metabolism 2007 56 12 1708 1713 10.1016/j.metabol.2007.07.015 17998025 (Pubitemid 350064590)
7. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. Tuomilehto J, Lindstrom J, Eriksson JG, Valle TT, Hamalainen H, Ilanne-Parikka P, Keinanen-Kiukaanniemi S, Laakso M, Louheranta A, Rastas M, et al. New Engl J Med 2001 344 18 1343 1350 10.1056/NEJM200105033441801 11333990 (Pubitemid 32378388)
8. Relation of weight change to changes in atherogenic traits: the Framingham Study. Ashley FW Jr, Kannel WB, J Chron Dis 1974 27 3 103 114 10.1016/0021-9681(74)90079-4 4830839
9. Systematic review of long-term lifestyle interventions to prevent weight gain and morbidity in adults. Brown T, Avenell A, Edmunds LD, Moore H, Whittaker V, Avery L, Summerbell C, Obes Rev 2009 10 6 627 638 10.1111/j.1467-789X.2009. 00641.x 19754634
10. The prevalence and determinants of obesity in adults with intellectual disabilities. Melville CA, Hamilton S, Hankey CR, Miller S, Boyle S, Obes Rev 2007 8 3 223 230 10.1111/j.1467-789X.2006.00296.x 17444964 (Pubitemid 46632693)
11. Central obesity and the aging brain. Jagust W, Harvey D, Mungas D, Haan M, Arch Neurol 2005 62 10 1545 1548 16216937 (Pubitemid 41434559)
12. Metabolic syndrome and cognitive decline. Yaffe K, Curr Alzheimer Res 2007 4 2 123 126 10.2174/156720507780362191 17430234 (Pubitemid 46557499)
13. The metabolic syndrome, inflammation, and risk of cognitive decline. Yaffe K, Kanaya A, Lindquist K, Simonsick EM, Harris T, Shorr RI, Tylavsky FA, Newman AB, JAMA 2004 292 18 2237 2242 10.1001/jama.292.18.2237 15536110 (Pubitemid 39473161)
14. Association of C-reactive protein with cognitive impairment. Noble JM, Manly JJ, Schupf N, Tang MX, Mayeux R, Luchsinger JA, Arch Neurol 2010 67 1 87 92 20065134
15. Insulin and leptin as adiposity signals. Benoit SC, Clegg DJ, Seeley RJ, Woods SC, Recent Progr Horm Res 2004 59 267 285 10.1210/rp.59.1.267 14749506 (Pubitemid 41327155)
16. Adiposity and Alzheimer's disease. Luchsinger JA, Mayeux R, Curr Alzheimer Res 2007 4 2 127 134 10.2174/156720507780362100 17430235 (Pubitemid 46562392)
17. Metabolic syndrome and Alzheimer's disease: a link to a vascular hypothesis? Milionis HJ, Florentin M, Giannopoulos S, CNS spectrums 2008 13 7 606 613 18622365
18. Brain-derived neurotrophic factor (BDNF) and food intake regulation: a minireview. Lebrun B, Bariohay B, Moyse E, Jean A, (Auton Neurosci: basic & clinical 2006 126-127 30 38 (Pubitemid 43833352)
19. Molecular cloning and expression of brain-derived neurotrophic factor. Leibrock J, Lottspeich F, Hohn A, Hofer M, Hengerer B, Masiakowski P, Thoenen H, Barde YA, Nature 1989 341 6238 149 152 10.1038/341149a0 2779653 (Pubitemid 19222776)
20. Purification and identification of brain-derived neurotrophic factor from human serum. Rosenfeld RD, Zeni L, Haniu M, Talvenheimo J, Radka SF, Bennett L, Miller JA, Welcher AA, Protein Expr Purif 1995 6 4 465 471 10.1006/prep.1995. 1062 8527932
21. Transport of brain-derived neurotrophic factor across the blood-brain barrier. Pan W, Banks WA, Fasold MB, Bluth J, Kastin AJ, Neuropharmacology 1998 37 12 1553 1561 10.1016/S0028-3908(98)00141-5 9886678 (Pubitemid 28550429)
22. Role for brain-derived neurotrophic factor in learning and memory. Yamada K, Mizuno M, Nabeshima T, Life Sciences 2002 70 7 735 744 10.1016/S0024- 3205(01)01461-8 11833737 (Pubitemid 34075562)
23. Serum brain-derived neurotrophic factor in bipolar and unipolar depression: a potential adjunctive tool for differential diagnosis. Fernandes BS, Gama CS, Kauer-Sant'Anna M, Lobato MI, Belmonte-de-Abreu P, Kapczinski F, (J Psychiatr Res 2009 43 15 1200 1204 10.1016/j.jpsychires.2009.04.010 19501841
24. A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression. Brunoni AR, Lopes M, Fregni F, Int J Neuropsychopharmacol 2008 11 8 1169 1180 10.1017/S1461145708009309 18752720
25. Long-term infusion of brain-derived neurotrophic factor reduces food intake and body weight via a corticotrophin-releasing hormone pathway in the paraventricular nucleus of the hypothalamus. Toriya M, Maekawa F, Maejima Y, Onaka T, Fujiwara K, Nakagawa T, Nakata M, Yada T, J Neuroendocrinol 2010 22 9 987 995 10.1111/j.1365-2826.2010.02039.x 20561155
26. Brain-derived neurotrophic factor regulates glucose metabolism by modulating energy balance in diabetic mice. Nakagawa T, Tsuchida A, Itakura Y, Nonomura T, Ono M, Hirota F, Inoue T, Nakayama C, Taiji M, Noguchi H, Diabetes 2000 49 3 436 444 10.2337/diabetes.49.3.436 10868966 (Pubitemid 30131790)
27. Serum brain-derived neurotrophic factor level is increased and associated with obesity in newly diagnosed female patients with type 2 diabetes mellitus. Suwa M, Kishimoto H, Nofuji Y, Nakano H, Sasaki H, Radak Z, Kumagai S, Metabol Clin Exp 2006 55 7 852 857 10.1016/j.metabol.2006.02.012 (Pubitemid 43902888)
28. Circulating brain-derived neurotrophic factor and indices of metabolic and cardiovascular health: data from the Baltimore Longitudinal Study of Aging. Golden E, Emiliano A, Maudsley S, Windham BG, Carlson OD, Egan JM, Driscoll I, Ferrucci L, Martin B, Mattson MP, PLos One 2010 5 4 10099 10.1371/journal.pone. 0010099 20404913
29. BDNF, metabolic risk factors, and resistance training in middle-aged individuals. Levinger I, Goodman C, Matthews V, Hare DL, Jerums G, Garnham A, Selig S, Med Sci Sports Exerc 2008 40 3 535 541 18379218 (Pubitemid 351294671)
30. Brain-derived neurotrophic factor (BDNF) and type 2 diabetes. Krabbe KS, Nielsen AR, Krogh-Madsen R, Plomgaard P, Rasmussen P, Erikstrup C, Fischer CP, Lindegaard B, Petersen AM, Taudorf S, et al. Diabetologia 2007 50 2 431 438 10.1007/s00125-006-0537-4 17151862
31. NGF, BDNF, leptin, and mast cells in human coronary atherosclerosis and metabolic syndrome. Chaldakov GN, Fiore M, Stankulov IS, Hristova M, Antonelli A, Manni L, Ghenev PI, Angelucci F, Aloe L, Arch Physiol Biochem 2001 109 4 357 360 10.1076/apab.109.4.357.4249 11935372 (Pubitemid 35216883)
32. Sex-dependent metabolic, neuroendocrine, and cognitive responses to dietary energy restriction and excess. Martin B, Pearson M, Kebejian L, Golden E, Keselman A, Bender M, Carlson O, Egan J, Ladenheim B, Cadet JL, et al. Endocrinology 2007 148 9 4318 4333 10.1210/en.2007-0161 17569758 (Pubitemid 47295690)
33. A Self-Rating Depression Scale. Zung WW, Arch Gen Psychiatr 1965 12 63 70 10.1001/archpsyc.1965.01720310065008 14221692
34. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC, Diabetologia 1985 28 7 412 419 10.1007/BF00280883 3899825 (Pubitemid 15018832)
35. Brain-derived neurotrophic factor not associated with metabolic syndrome but inversely correlated with vascular cell adhesion molecule-1 in men without diabetes. Lee IT, Lee WJ, Tsai IC, Liang KW, Lin SY, Wan CJ, Fu CP, Sheu WH, Clin Chim Acta 2012 413 9-10 944 948 10.1016/j.cca.2012.02.013 22374129
36. Role of exercise-induced brain-derived neurotrophic factor production in the regulation of energy homeostasis in mammals. Pedersen BK, Pedersen M, Krabbe KS, Bruunsgaard H, Matthews VB, Febbraio MA, Exp Physiol 2009 94 12 1153 1160 10.1113/expphysiol.2009.048561 19748969
37. Endurance training increases plasma brain-derived neurotrophic factor concentration in young healthy men. Zoladz JA, Pilc A, Majerczak J, Grandys M, Zapart-Bukowska J, Duda K, J Physiol Pharmacol 2008 59 Suppl 7 119 132 19258661
38. Effects of physical exercise on plasma levels of brain-derived neurotrophic factor and depressive symptoms in elderly women-a randomized clinical trial. Pereira DS, de Queiroz BZ, Miranda AS, Rocha NP, Felicio DC, Mateo EC, Favero M, Coelho FM, Jesus-Moraleida F, Gomes Pereira DA, et al. Arch Phys Med Rehabil 2013 94 8 1443 1450 10.1016/j.apmr.2013.03.029 23602881
39. Kinetics of serum brain-derived neurotrophic factor following low-intensity versus high-intensity exercise in men and women. Schmidt-Kassow M, Schadle S, Otterbein S, Thiel C, Doehring A, Lotsch J, Kaiser J, Neuroreport 2012 23 15 889 893 10.1097/WNR.0b013e32835946ca 22964969
40. Effects of aerobic exercise on mild cognitive impairment: a controlled trial. Baker LD, Frank LL, Foster-Schubert K, Green PS, Wilkinson CW, McTiernan A, Plymate SR, Fishel MA, Watson GS, Cholerton BA, et al. Arch Neurol 2010 67 1 71 79 20065132
41. Lifestyle modification and behavior therapy effectively reduce body weight and increase serum level of brain-derived neurotrophic factor in obese non-diabetic patients with schizophrenia. Kuo FC, Lee CH, Hsieh CH, Kuo P, Chen YC, Hung YJ, Psychiatr Res 2013 209 2 150 154 10.1016/j.psychres.2012.11.020
42. The role of brain-derived neurotrophic factor (BDNF) gene variants in antipsychotic response and antipsychotic-induced weight gain. Zai GC, Zai CC, Chowdhury NI, Tiwari AK, Souza RP, Lieberman JA, Meltzer HY, Potkin SG, Muller DJ, Kennedy JL, Progr Neuro Psychopharmacol Biol Psychiatr 2012 39 1 96 101 10.1016/j.pnpbp.2012.05.014
43. Evidence for a release of brain-derived neurotrophic factor from the brain during exercise. Rasmussen P, Brassard P, Adser H, Pedersen MV, Leick L, Hart E, Secher NH, Pedersen BK, Pilegaard H, Exp Physiol 2009 94 10 1062 1069 10.1113/expphysiol.2009.048512 19666694
44. New insights into BDNF function in depression and anxiety. Martinowich K, Manji H, Lu B, Nat Neurosci 2007 10 9 1089 1093 10.1038/nn1971 17726474 (Pubitemid 47339961)
45. Psychobiological effects observed in obese men experiencing body weight loss plateau. Chaput JP, Drapeau V, Hetherington M, Lemieux S, Provencher V, Tremblay A, Depress Anxiety 2007 24 7 518 521 10.1002/da.20264 17131351 (Pubitemid 350086264)
46. Elevated depressive symptoms are associated with hypertriglyceridemia in Japanese male workers. Kamezaki F, Sonoda S, Nakata S, Okazaki M, Tamura M, Abe H, Takeuchi M, Otsuji Y, Intern Med 2011 50 21 2485 2490 10.2169/ internalmedicine.50.5667 22041346
47. Psychobiological impact of a progressive weight loss program in obese men. Chaput JP, Drapeau V, Hetherington M, Lemieux S, Provencher V, Tremblay A, Physiol Behav 2005 86 1-2 224 232 16112692 (Pubitemid 41316626)
48. Association of major depression and binge eating disorder with weight loss in a clinical setting. Pagoto S, Bodenlos JS, Kantor L, Gitkind M, Curtin C, Ma Y, Obesity 2007 15 11 2557 2559 10.1038/oby.2007.307 18070746
49. Does depression reduce the effectiveness of behavioral weight loss treatment? Ludman E, Simon GE, Ichikawa LE, Operskalski BH, Arterburn D, Linde JA, Jeffery RW, Rohde P, Finch EA, Behav Med 2010 35 4 126 134 19933059
50. One-year changes in symptoms of depression and weight in overweight/obese individuals with type 2 diabetes in the Look AHEAD study. Faulconbridge LF, Wadden TA, Rubin RR, Wing RR, Walkup MP, Fabricatore AN, Coday M, Van Dorsten B, Mount DL, Ewing LJ, et al. Obesity 2012 20 4 783 793 10.1038/oby.2011.315 22016099
51. Decreased serum brain-derived neurotrophic factor concentration in young nonobese subjects with low insulin sensitivity. Karczewska-Kupczewska M, Straczkowski M, Adamska A, Nikolajuk A, Otziomek E, Gorska M, Kowalska I, Clin Biochem 2011 44 10-11 817 820 21620811
52. Central nervous system circuitry involved in the hyperinsulinism syndrome. Lechin F, van der Dijs B, Neuroendocrinology 2006 84 4 222 234 10.1159/000098005 17167239 (Pubitemid 46391713)
53. CNS-targets in control of energy and glucose homeostasis. Kleinridders A, Konner AC, Bruning JC, Curr Opin Pharmacol 2009 9 6 794 804 10.1016/j.coph.2009.10.006 19884043
54. Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants. Shimizu E, Hashimoto K, Okamura N, Koike K, Komatsu N, Kumakiri C, Nakazato M, Watanabe H, Shinoda N, Okada S, et al. Biol Psychiatr 2003 54 1 70 75 10.1016/S0006-3223(03)00181-1 (Pubitemid 36776725)
55. Effect of the look AHEAD study intervention on medication use and related cost to treat cardiovascular disease risk factors in individuals with type 2 diabetes. Redmon JB, Bertoni AG, Connelly S, Feeney PA, Glasser SP, Glick H, Greenway F, Hesson LA, Lawlor MS, Montez M, et al. Diabetes Care 2010 33 6 1153 1158 10.2337/dc09-2090 20332353
56. Four-year analysis of cardiovascular disease risk factors, depression symptoms, and antidepressant medicine use in the Look AHEAD (Action for Health in Diabetes) clinical trial of weight loss in diabetes. Rubin RR, Peyrot M, Gaussoin SA, Espeland MA, Williamson D, Faulconbridge LF, Wadden TA, Ewing L, Safford M, Evans-Hudnall G, et al. Diabetes Care 2013 36 5 1088 1094 10.2337/dc12-1871 23359362
57. Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. Look ARG, Wing RR, Bolin P, Brancati FL, Bray GA, Clark JM, Coday M, Crow RS, Curtis JM, Egan CM, et al. New Engl J Med 2013 369 2 145 154 23796131
58. Circulating brain-derived neurotrophic factor concentration is downregulated by intralipid/heparin infusion or high-fat meal in young healthy male subjects. Karczewska-Kupczewska M, Kowalska I, Nikolajuk A, Adamska A, Zielinska M, Kaminska N, Otziomek E, Gorska M, Straczkowski M, Diabetes Care 2012 35 2 358 362 10.2337/dc11-1295 22210566
59. Plasma BDNF levels vary in relation to body weight in females. Pillai A, Bruno D, Sarreal AS, Hernando RT, Saint-Louis LA, Nierenberg J, Ginsberg SD, Pomara N, Mehta PD, Zetterberg H, et al. PloS One 2012 7 7 39358 10.1371/journal.pone.0039358 22768299
60. Critical role of brain-derived neurotrophic factor in mood disorders. Hashimoto K, Shimizu E, Iyo M, Brain Res Rev 2004 45 2 104 114 10.1016/j.brainresrev.2004.02.003 15145621 (Pubitemid 38625738)
61. Brain-derived neurotrophic factor as a biomarker for mood disorders: an historical overview and future directions. Hashimoto K, Psychiatr Clin Neurosci 2010 64 4 341 357 10.1111/j.1440-1819.2010.02113.x
62. Brain-derived neurotrophic factor predicts mortality risk in older women. Krabbe KS, Mortensen EL, Avlund K, Pedersen AN, Pedersen BK, Jorgensen T, Bruunsgaard H, J Am Geriatr Soc 2009 57 8 1447 1452 10.1111/j.1532-5415.2009. 02345.x 19515111