Hypertension promotes islet morphological changes with vascular injury on pre-diabetic status in SHRsp rats

Clinical and Experimental Hypertension

Volumn 36, Issue 3, 2014, Pages 159-164

  Satoh, Minoru ^a   Nagasu, Hajime ^a   Haruna, Yoshisuke ^a   Ihoriya, Chieko ^a   Kadoya, Hiroyuki ^a   Sasaki, Tamaki ^a   Kashihara, Naoki ^a  

^a KAWASAKI MEDICAL SCHOOL   (Japan)

Author keywords

Angiotensin II receptor blocker; Diabetes mellitus; Endothelial injury; Epithelial to mesenchymal transition; Islet fibrosis

Indexed keywords

HYDRALAZINE; INSULIN; IRBESARTAN; ANTIHYPERTENSIVE AGENT; BIPHENYL DERIVATIVE; TETRAZOLE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; BLOOD VESSEL INJURY; CELL INFILTRATION; CONTROLLED STUDY; CYSTIC FIBROSIS; EPITHELIAL MESENCHYMAL TRANSITION; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE; HISTOPATHOLOGY; HYPERTENSION; IMPAIRED GLUCOSE TOLERANCE; LIPID DIET; MACROPHAGE; MALE; NONHUMAN; PANCREAS; PANCREAS ISLET; RAT; STRAIN DIFFERENCE; STROKE PRONE SPONTANEOUSLY HYPERTENSIVE RAT; WISTAR KYOTO RAT; ANIMAL; CHEMICALLY INDUCED; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPONTANEOUSLY HYPERTENSIVE RAT;

ANIMALS; ANTIHYPERTENSIVE AGENTS; BIPHENYL COMPOUNDS; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; HYDRALAZINE; HYPERTENSION; ISLETS OF LANGERHANS; MALE; PREDIABETIC STATE; RATS, INBRED SHR; TETRAZOLES; VASCULAR SYSTEM INJURIES;

EID: 84894088198     PISSN: 10641963     EISSN: 15256006     Source Type: Journal    
DOI: 10.3109/10641963.2013.804539     Document Type: Article

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