Hydroxycamptothecin liposomes inhibit collagen secretion and induce fibroblast apoptosis in a postlaminectomy rabbit model

European Journal of Orthopaedic Surgery and Traumatology

Volumn 23, Issue SUPPL. 1, 2013, Pages

  Zhu, Liang ^a,b   Ni, Bin ^b   Liu, Jun ^c   Yang, Jun ^b   Guo, Qunfeng ^b   Zhou, Wei ^d  

^a SHANGHAI FIRST PEOPLE S HOSPITAL   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c NANJING MEDICAL UNIVERSITY   (China)

^d NANJING TECH UNIVERSITY   (China)

Author keywords

Fibroblasts; Fibrosis; Hydroxycamptothecin; Laminectomy; Liposomes

Indexed keywords

CAMPTOTHECIN DERIVATIVE; COLLAGEN; HYDROXYCAMPTOTHECIN; HYDROXYPROLINE; LIPOSOME; UNCLASSIFIED DRUG; CAMPTOTHECIN; HYDROXYCAMPTOTHECINUM; DRUG DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL COUNT; CONTROLLED STUDY; DRUG EFFICACY; DRUG RESPONSE; DURA MATER; EPIDURAL FIBROSIS; FIBROBLAST; FIBROSIS; HISTOLOGY; LAMINECTOMY; MALE; NERVE ROOT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; ANALOGS AND DERIVATIVES; ANIMAL; DISEASE MODEL; DRUG DELIVERY SYSTEM; DRUG EFFECTS; EPIDURAL SPACE; METABOLISM; PATHOLOGY; POSTOPERATIVE COMPLICATIONS; PROCEDURES; RABBIT; SCAR; SECRETION (PROCESS); SECRETORY PATHWAY; TISSUE ADHESIONS; DRUG EFFECT; METHODOLOGY; POSTOPERATIVE COMPLICATION; TISSUE ADHESION;

ANIMALS; CAMPTOTHECIN; CICATRIX; COLLAGEN; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; EPIDURAL SPACE; FIBROBLASTS; LAMINECTOMY; LIPOSOMES; MAGNETIC RESONANCE IMAGING; MALE; POSTOPERATIVE COMPLICATIONS; RABBITS; SECRETORY PATHWAY; TISSUE ADHESIONS;

EID: 84894067534     PISSN: 16338065     EISSN: 14321068     Source Type: Journal    
DOI: 10.1007/s00590-012-0971-6     Document Type: Article

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