Bioavailability of hydrochlorothiazide from pellets, made by extrusion/spheronisation, containing polyethylene glycol 400 as a dissolution enhancer

Pharmaceutical Research

Volumn 14, Issue 11, 1997, Pages 1644-1646

  Vervaet, Chris ^a   Remon, Jean Paul ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Cyclodextrins; HCT; Hydroflumethiazide

Indexed keywords

HYDROCHLOROTHIAZIDE; MACROGOL 400; MICROCRYSTALLINE CELLULOSE;

ADULT; ARTICLE; CONTROLLED STUDY; DISSOLUTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG MANUFACTURE; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TABLET FORMULATION; ULTRAVIOLET SPECTROPHOTOMETRY;

ADJUVANTS, PHARMACEUTIC; ADMINISTRATION, ORAL; ADULT; BIOLOGICAL AVAILABILITY; CROSS-OVER STUDIES; DRUG COMPOUNDING; DRUG IMPLANTS; HUMANS; HYDROCHLOROTHIAZIDE; MALE; MIDDLE AGED; POLYETHYLENE GLYCOLS; RANDOM ALLOCATION; SOLUBILITY;

EID: 0031469675     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012151006742     Document Type: Article

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