HNRNPA1 regulates HMGCR alternative splicing and modulates cellular cholesterol metabolism

Human Molecular Genetics

Volumn 23, Issue 2, 2014, Pages 319-332

  Yu, Chi Yi ^a   Theusch, Elizabeth ^a   Lo, Kathleen ^a   Mangravite, Lara M ^b   Naidoo, Devesh ^a   Kutilova, Mariya ^a   Medina, Marisa W ^a  

^a CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^b SAGE BIONETWORKS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; SIMVASTATIN; STEROL; UNCLASSIFIED DRUG;

ALLELE; ALTERNATIVE RNA SPLICING; ARTICLE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL METABOLISM; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; ENZYME ACTIVITY; EXON; FOLLOW UP; GENE EXPRESSION; HEPATOCELLULAR CARCINOMA CELL LINE; HUMAN; HUMAN CELL; LIVER CELL; LYMPHOBLASTOID CELL LINE; PLASMA; PRIORITY JOURNAL; RNA SPLICING; SIGNAL TRANSDUCTION;

ALLELES; ALTERNATIVE SPLICING; APOLIPOPROTEINS B; CELL LINE, TUMOR; CHOLESTEROL, LDL; EXONS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC VARIATION; HEP G2 CELLS; HEPATOCYTES; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN GROUP A-B; HUMANS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN BINDING; RNA STABILITY;

EID: 84894056238     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt422     Document Type: Article

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