-
1
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
-
Ferlay J, Shin HR, Bray F et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J. Cancer 127, 2893-2917 (2010).
-
(2010)
Int J. Cancer
, vol.127
, pp. 2893-2917
-
-
Ferlay, J.1
Shin, H.R.2
Bray, F.3
-
2
-
-
34548457234
-
The IASLC Lung Cancer Staging Project: Proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours
-
Goldstraw P, Crowley J, Chansky K et al. The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours. J. Thorac. Oncol. 2, 706-714 (2007).
-
(2007)
J. Thorac. Oncol.
, vol.2
, pp. 706-714
-
-
Goldstraw, P.1
Crowley, J.2
Chansky, K.3
-
3
-
-
49049089802
-
Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced stage non-small cell lung cancer
-
Scagliotti G, Parikh P, Von Pawel J et al. Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced stage non-small cell lung cancer. J. Clin. Oncol. 26, 3543-3551 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 3543-3551
-
-
Scagliotti, G.1
Parikh, P.2
Von Pawel, J.3
-
4
-
-
69949186250
-
Screening for epidermal growth factor receptor mutations in lung cancer
-
Rosell R, Moran T, Queralt C et al. Screening for epidermal growth factor receptor mutations in lung cancer. N. Engl. J. Med. 361, 958-967 (2009).
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 958-967
-
-
Rosell, R.1
Moran, T.2
Queralt, C.3
-
5
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'Day SJ, McDermott DF et al. Improved survival with ipilimumab in patients with metastatic melanoma. N. Engl. J. Med. 363, 711-723 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
-
6
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
Kantoff PW, Higano CS, Shore ND et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N. Engl. J. Med. 363, 411-422 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
-
7
-
-
45549092607
-
Cancer immunology
-
Finn OJ. Cancer immunology. N. Engl. J. Med. 358, 2704-2715 (2008).
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 2704-2715
-
-
Finn, O.J.1
-
8
-
-
0032546352
-
Dendritic cells and the control of immunity
-
Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 392, 245-252 (1998).
-
(1998)
Nature
, vol.392
, pp. 245-252
-
-
Banchereau, J.1
Steinman, R.M.2
-
9
-
-
77957114732
-
Targeting the immune system in non-small cell lung cancer: Bridging the gap between promising concept and therapeutic reality
-
Kelly RJ, Gulley JL, Giaccone G. Targeting the immune system in non-small cell lung cancer: bridging the gap between promising concept and therapeutic reality. Clin. Lung Cancer 11, 228-237 (2010).
-
(2010)
Clin. Lung Cancer
, vol.11
, pp. 228-237
-
-
Kelly, R.J.1
Gulley, J.L.2
Giaccone, G.3
-
12
-
-
55949083407
-
Anti-cytotoxic T-lymphocyte antigen-4 antibody: The first in an emerging class of immunomodulatory antibodies for cancer treatment
-
Fong L, Small EJ. Anti-cytotoxic T-lymphocyte antigen-4 antibody: the first in an emerging class of immunomodulatory antibodies for cancer treatment. J. Clin. Oncol. 26, 5275-5283 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 5275-5283
-
-
Fong, L.1
Small, E.J.2
-
13
-
-
0036623140
-
Immune escape of tumors: Apoptosis resistance and tumor counterattack
-
Igney FH, Krammer PH. Immune escape of tumors: apoptosis resistance and tumor counterattack. J. Leukoc. Biol. 71, 907-920 (2002).
-
(2002)
J. Leukoc. Biol.
, vol.71
, pp. 907-920
-
-
Igney, F.H.1
Krammer, P.H.2
-
14
-
-
31444439350
-
Concurrent infiltration by CD8+ T cells and CD4+ T cells is a favourable prognostic factor in non-small cell lung carcinoma
-
Hiraoka K, Miyamoto M, Cho Y et al. Concurrent infiltration by CD8+ T cells and CD4+ T cells is a favourable prognostic factor in non-small cell lung carcinoma. Br. J. Cancer (2006).
-
(2006)
Br. J. Cancer
-
-
Hiraoka, K.1
Miyamoto, M.2
Cho, Y.3
-
15
-
-
52649163840
-
Prognostic effect of epithelial and stromal lymphocyte infiltration in non-small cell lung cancer
-
Al-Shibli KI, Donnem T, Al-Saad S et al. Prognostic effect of epithelial and stromal lymphocyte infiltration in non-small cell lung cancer. Clin. Cancer Res. 14, 5220-5227 (2008).
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 5220-5227
-
-
Al-Shibli, K.I.1
Donnem, T.2
Al-Saad, S.3
-
16
-
-
53149083361
-
Predominant infiltration of macrophages and CD8+ T cells in cancer nests is a significant predictor of survival in stage IV non-small cell lung cancer
-
Kawai O, Ishii G, Kubota K et al. Predominant infiltration of macrophages and CD8+ T cells in cancer nests is a significant predictor of survival in stage IV non-small cell lung cancer. Cancer 113, 1387-1395 (2008).
-
(2008)
Cancer
, vol.113
, pp. 1387-1395
-
-
Kawai, O.1
Ishii, G.2
Kubota, K.3
-
17
-
-
33845590308
-
Tumor infiltrating Foxp3+ regulatory T-cells are associated with recurrence in pathologic stage I NSCLC patients
-
Petersen RP, Campa MJ, Sperlazza J et al. Tumor infiltrating Foxp3+ regulatory T-cells are associated with recurrence in pathologic stage I NSCLC patients. Cancer 107, 2866-2872 (2006).
-
(2006)
Cancer
, vol.107
, pp. 2866-2872
-
-
Petersen, R.P.1
Campa, M.J.2
Sperlazza, J.3
-
18
-
-
77951877847
-
Tumor-infiltrating Foxp3+ regulatory T cells are correlated with cyclooxygenase-2 expression and are associated with recurrence in resected non-small cell lung cancer
-
Shimizu K, Nakata M, Hirami Y et al. Tumor-infiltrating Foxp3+ regulatory T cells are correlated with cyclooxygenase-2 expression and are associated with recurrence in resected non-small cell lung cancer. J. Thorac. Oncol. 5, 585-590 (2010).
-
(2010)
J. Thorac. Oncol.
, vol.5
, pp. 585-590
-
-
Shimizu, K.1
Nakata, M.2
Hirami, Y.3
-
19
-
-
65349116059
-
Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): An open-label randomized Phase III trial
-
Pirker R, Pereira JR, Szczesna A et al. Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomized Phase III trial. Lancet 373, 1525-1531 (2009).
-
(2009)
Lancet
, vol.373
, pp. 1525-1531
-
-
Pirker, R.1
Pereira, J.R.2
Szczesna, A.3
-
20
-
-
84861731964
-
Vaccination therapy for non-small cell lung cancer: Review of agents in Phase III development
-
Decoster L, Wauters I, Vansteenkiste J. Vaccination therapy for non-small cell lung cancer: review of agents in Phase III development. Ann. Oncol. 23, 1387-1393 (2012).
-
(2012)
Ann. Oncol.
, vol.23
, pp. 1387-1393
-
-
Decoster, L.1
Wauters, I.2
Vansteenkiste, J.3
-
21
-
-
0029099362
-
Identification of MAGE-1 and MAGE-4 proteins in spermatogonia and primary spermatocytes of testis
-
Takahashi K, Shichijo S, Noguchi M et al. Identification of MAGE-1 and MAGE-4 proteins in spermatogonia and primary spermatocytes of testis. Cancer Res. 55, 3478-3482 (1995).
-
(1995)
Cancer Res.
, vol.55
, pp. 3478-3482
-
-
Takahashi, K.1
Shichijo, S.2
Noguchi, M.3
-
22
-
-
28144457350
-
Cancer-testis genes are coordinately expressed and are markers of poor outcome in non-small cell lung cancer
-
Gure AO, Chua R, Williamson B et al. Cancer-testis genes are coordinately expressed and are markers of poor outcome in non-small cell lung cancer. Clin. Cancer Res. 11, 8055-8062 (2005).
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 8055-8062
-
-
Gure, A.O.1
Chua, R.2
Williamson, B.3
-
23
-
-
0347364737
-
Melanoma associated antigen (MAGE)-A3 expression in stages I and II non-small cell lung cancer: Results of a multi-center study
-
Sienel W, Varwerk C, Linder A et al. Melanoma associated antigen (MAGE)-A3 expression in stages I and II non-small cell lung cancer: results of a multi-center study. Eur. J. Cardiothorac. Surg. 25, 131-134 (2004).
-
(2004)
Eur. J. Cardiothorac. Surg.
, vol.25
, pp. 131-134
-
-
Sienel, W.1
Varwerk, C.2
Linder, A.3
-
24
-
-
84880755387
-
Adjuvant MAGE-A3 immunotherapy in resected non-small cell lung cancer: Phase II randomized study results
-
Vansteenkiste J, Zielinski M, Linder A et al. Adjuvant MAGE-A3 immunotherapy in resected non-small cell lung cancer: Phase II randomized study results. J. Clin. Oncol. 31, 2396-2403 (2013).
-
(2013)
J. Clin. Oncol.
, vol.31
, pp. 2396-2403
-
-
Vansteenkiste, J.1
Zielinski, M.2
Linder, A.3
-
25
-
-
84880720167
-
Predictive gene signature in MAGEA3 antigen-specific cancer immunotherapy
-
Ulloa-Montoya F, Louahed J, Dizier B et al. Predictive gene signature in MAGEA3 antigen-specific cancer immunotherapy. J. Clin. Oncol. 31, 2388-2395 (2013).
-
(2013)
J. Clin. Oncol.
, vol.31
, pp. 2388-2395
-
-
Ulloa-Montoya, F.1
Louahed, J.2
Dizier, B.3
-
26
-
-
17844390172
-
Epidermal growth factor receptor mutations, small-molecule kinase inhibitors, and non-small cell lung cancer: Current knowledge and future directions
-
Pao W, Miller VA. Epidermal growth factor receptor mutations, small-molecule kinase inhibitors, and non-small cell lung cancer: current knowledge and future directions. J. Clin. Oncol. 23, 2556-2568 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 2556-2568
-
-
Pao, W.1
Miller, V.A.2
-
27
-
-
0031775979
-
A novel cancer vaccine composed of human-recombinant epidermal growth factor linked to a carrier protein: Report of a pilot clinical trial
-
Gonzalez G, Crombet T, Catala M et al. A novel cancer vaccine composed of human-recombinant epidermal growth factor linked to a carrier protein: report of a pilot clinical trial. Ann. Oncol. 9, 431-435 (1998).
-
(1998)
Ann. Oncol.
, vol.9
, pp. 431-435
-
-
Gonzalez, G.1
Crombet, T.2
Catala, M.3
-
28
-
-
41149159650
-
Phase II randomized controlled trial of an epidermal growth factor vaccine in advanced non-small cell lung cancer
-
Neninger Vinageras E, De La Torre A, Osorio Rodriguez M et al. Phase II randomized controlled trial of an epidermal growth factor vaccine in advanced non-small cell lung cancer. J. Clin. Oncol. 26, 1452-1458 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 1452-1458
-
-
Neninger Vinageras, E.1
De La Torre, A.2
Osorio Rodriguez, M.3
-
29
-
-
77649229271
-
Clinical development and perspectives of CIMAvax EGF, Cuban vaccine for non-small cell lung cancer therapy
-
Rodriguez PC, Rodriguez G, Gonzalez G et al. Clinical development and perspectives of CIMAvax EGF, Cuban vaccine for non-small cell lung cancer therapy. MEDICC Rev. 12, 17-23 (2010).
-
(2010)
MEDICC Rev.
, vol.12
, pp. 17-23
-
-
Rodriguez, P.C.1
Rodriguez, G.2
Gonzalez, G.3
-
30
-
-
1142286444
-
MUC1 immunobiology: From discovery to clinical applications
-
Vlad AM, Kettel JC, Alajez NM et al. MUC1 immunobiology: from discovery to clinical applications. Adv. Immunol. 82, 249-293 (2004).
-
(2004)
Adv. Immunol.
, vol.82
, pp. 249-293
-
-
Vlad, A.M.1
Kettel, J.C.2
Alajez, N.M.3
-
31
-
-
34547661985
-
L-BLP25: A peptide vaccine strategy in non-small cell lung cancer
-
Sangha R, Butts C. L-BLP25: a peptide vaccine strategy in non-small cell lung cancer. Clin. Cancer Res. 13, 4652s-4654s (2007).
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 4652s-4654s
-
-
Sangha, R.1
Butts, C.2
-
32
-
-
33748055445
-
MUC1 oncoprotein blocks nuclear targeting of c-Abl in the apoptotic response to DNA damage
-
Raina D, Ahmad R, Kumar S et al. MUC1 oncoprotein blocks nuclear targeting of c-Abl in the apoptotic response to DNA damage. EMBO J. 25, 3774-3783 (2006).
-
(2006)
EMBO J.
, vol.25
, pp. 3774-3783
-
-
Raina, D.1
Ahmad, R.2
Kumar, S.3
-
33
-
-
0041850346
-
Human DF3/MUC1 carcinoma-associated protein functions as an oncogene
-
Li Y, Liu D, Chen D et al. Human DF3/MUC1 carcinoma-associated protein functions as an oncogene. Oncogene 22, 6107-6110 (2003).
-
(2003)
Oncogene
, vol.22
, pp. 6107-6110
-
-
Li, Y.1
Liu, D.2
Chen, D.3
-
34
-
-
0042818006
-
Human MUC1 carcinoma antigen regulates intracellular oxidant levels and the apoptotic response to oxidative stress
-
Yin L, Li Y, Ren J et al. Human MUC1 carcinoma antigen regulates intracellular oxidant levels and the apoptotic response to oxidative stress. J. Biol. Chem. 278, 35458-35464 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 35458-35464
-
-
Yin, L.1
Li, Y.2
Ren, J.3
-
35
-
-
50349090322
-
A Phase II study of Tg4010 (Mva-Muc1-Il2) in association with chemotherapy in patients with stage III/IV non-small cell lung cancer
-
Ramlau R, Quoix E, Rolski J et al. A Phase II study of Tg4010 (Mva-Muc1-Il2) in association with chemotherapy in patients with stage III/IV non-small cell lung cancer. J. Thorac. Oncol. 3, 735-744 (2008).
-
(2008)
J. Thorac. Oncol.
, vol.3
, pp. 735-744
-
-
Ramlau, R.1
Quoix, E.2
Rolski, J.3
-
36
-
-
0031914321
-
Cancer-associated MUC1 mucin inhibits human T-cell proliferation, which is reversible by IL-2
-
Agrawal B, Krantz MJ, Reddish MA et al. Cancer-associated MUC1 mucin inhibits human T-cell proliferation, which is reversible by IL-2. Nat. Med. 4, 43-49 (1998).
-
(1998)
Nat. Med.
, vol.4
, pp. 43-49
-
-
Agrawal, B.1
Krantz, M.J.2
Reddish, M.A.3
-
37
-
-
81255127285
-
Therapeutic vaccination with TG4010 and first-line chemotherapy in advanced non-small cell lung cancer: A controlled Phase 2B trial
-
Quoix E, Ramlau R, Westeel V et al. Therapeutic vaccination with TG4010 and first-line chemotherapy in advanced non-small cell lung cancer: a controlled Phase 2B trial. Lancet Oncol. 12, 1125-1133 (2011).
-
(2011)
Lancet Oncol.
, vol.12
, pp. 1125-1133
-
-
Quoix, E.1
Ramlau, R.2
Westeel, V.3
-
39
-
-
27244449289
-
Randomized Phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non-small cell lung cancer
-
Butts C, Murray N, Maksymiuk A et al. Randomized Phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non-small cell lung cancer. J. Clin. Oncol. 23, 6674-6681 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 6674-6681
-
-
Butts, C.1
Murray, N.2
Maksymiuk, A.3
-
40
-
-
0032979212
-
Long survival of patients with small cell lung cancer after adjuvant treatment with the anti-idiotypic antibody BEC2 plus Bacillus Calmette-Guerin
-
Grant SC, Kris MG, Houghton AN et al. Long survival of patients with small cell lung cancer after adjuvant treatment with the anti-idiotypic antibody BEC2 plus Bacillus Calmette-Guerin. Clin. Cancer Res. 5, 1319-1323 (1999).
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 1319-1323
-
-
Grant, S.C.1
Kris, M.G.2
Houghton, A.N.3
-
41
-
-
27244446896
-
Phase III study of adjuvant vaccination with Bec2/Bacille Calmette-Guerin in responding patients with limited-disease small cell lung cancer (EORTC 08971-08971B; Silva study)
-
Giaccone G, Debruyne C, Felip E et al. Phase III study of adjuvant vaccination with Bec2/Bacille Calmette-Guerin in responding patients with limited-disease small cell lung cancer (EORTC 08971-08971B; Silva study). J. Clin. Oncol. 23, 6854-6864 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 6854-6864
-
-
Giaccone, G.1
Debruyne, C.2
Felip, E.3
-
42
-
-
0034844959
-
N-glycolylneuraminic acid in human tumours
-
Malykh YN, Schauer R, Shaw L. N-glycolylneuraminic acid in human tumours. Biochimie 83, 623-634 (2001).
-
(2001)
Biochimie
, vol.83
, pp. 623-634
-
-
Malykh, Y.N.1
Schauer, R.2
Shaw, L.3
-
43
-
-
84884586196
-
Racotumomab: An anti-idiotype vaccine related to N-glycolyl-containing gangliosides - Preclinical and clinical data
-
Vazquez AM, Hernandez AM, Macias A et al. Racotumomab: an anti-idiotype vaccine related to N-glycolyl-containing gangliosides - preclinical and clinical data. Front. Oncol. 2, 150 (2012).
-
(2012)
Front. Oncol.
, vol.2
, pp. 150
-
-
Vazquez, A.M.1
Hernandez, A.M.2
Macias, A.3
-
44
-
-
67349136455
-
Anti-ganglioside anti-idiotypic monoclonal antibody-based cancer vaccine induces apoptosis and antiangiogenic effect in a metastatic lung carcinoma
-
Diaz Y, Gonzalez A, Lopez A et al. Anti-ganglioside anti-idiotypic monoclonal antibody-based cancer vaccine induces apoptosis and antiangiogenic effect in a metastatic lung carcinoma. Cancer Immunol. Immunother. 58, 1117-1128 (2009).
-
(2009)
Cancer Immunol. Immunother.
, vol.58
, pp. 1117-1128
-
-
Diaz, Y.1
Gonzalez, A.2
Lopez, A.3
-
45
-
-
34247330975
-
Active immunotherapy with 1E10 anti-idiotype vaccine in patients with small cell lung cancer: Report of a Phase I trial
-
Neninger E, Diaz RM, De La Torre A et al. Active immunotherapy with 1E10 anti-idiotype vaccine in patients with small cell lung cancer: report of a Phase I trial. Cancer Biol. Ther. 6, 145-150 (2007).
-
(2007)
Cancer Biol. Ther.
, vol.6
, pp. 145-150
-
-
Neninger, E.1
Diaz, R.M.2
De La Torre, A.3
-
46
-
-
42549128373
-
1E10 anti-idiotype vaccine in non-small cell lung cancer: Experience in stage IIIb/IV patients
-
Alfonso S, Diaz RM, De La Torre A et al. 1E10 anti-idiotype vaccine in non-small cell lung cancer: experience in stage IIIb/IV patients. Cancer Biol. Ther. 6, 1847-1852 (2007).
-
(2007)
Cancer Biol. Ther.
, vol.6
, pp. 1847-1852
-
-
Alfonso, S.1
Diaz, R.M.2
De La Torre, A.3
-
47
-
-
10744229445
-
Granulocyte-macrophage colony-stimulating factor gene-modified autologous tumor vaccines in non-small cell lung cancer
-
Nemunaitis J, Sterman D, Jablons D et al. Granulocyte-macrophage colony-stimulating factor gene-modified autologous tumor vaccines in non-small cell lung cancer. J. Natl. Cancer Inst. 96, 326-331 (2004).
-
(2004)
J. Natl. Cancer Inst.
, vol.96
, pp. 326-331
-
-
Nemunaitis, J.1
Sterman, D.2
Jablons, D.3
-
48
-
-
33750586798
-
Phase II study of belagenpumatucel-L, a transforming growth factor β-2 antisense gene-modified allogeneic tumor cell vaccine in non-small cell lung cancer
-
Nemunaitis J, Dillman RO, Schwarzenberger PO et al. Phase II study of belagenpumatucel-L, a transforming growth factor β-2 antisense gene-modified allogeneic tumor cell vaccine in non-small cell lung cancer. J. Clin. Oncol. 24, 4721-4730 (2006).
-
(2006)
J. Clin. Oncol.
, vol.24
, pp. 4721-4730
-
-
Nemunaitis, J.1
Dillman, R.O.2
Schwarzenberger, P.O.3
-
49
-
-
77958590905
-
Correlation of immune responses and survival in a Phase II study of belagenpumatucel-L in non-small cell lung cancer
-
Abstract 3013
-
Fakhrai H, Tong A, Nemunaitis J et al. Correlation of immune responses and survival in a Phase II study of belagenpumatucel-L in non-small cell lung cancer. J. Clin. Oncol. 17, Abstract 3013 (2011).
-
(2011)
J. Clin. Oncol.
, vol.17
-
-
Fakhrai, H.1
Tong, A.2
Nemunaitis, J.3
-
50
-
-
0027949292
-
A placebo-controlled randomized double-blind study of adjuvant intrapleural BCG in patients with resected T1N0, T1N1, or T2N0 squamous cell carcinoma, adenocarcinoma, or large cell carcinoma of the lung. LCSG Protocol 771
-
Gail MH. A placebo-controlled randomized double-blind study of adjuvant intrapleural BCG in patients with resected T1N0, T1N1, or T2N0 squamous cell carcinoma, adenocarcinoma, or large cell carcinoma of the lung. LCSG Protocol 771. Chest 106, 287S-292S (1994).
-
(1994)
Chest
, vol.106
, pp. 287S-292S
-
-
Gail, M.H.1
-
51
-
-
0027995441
-
Surgical adjuvant therapy for stage II and stage III adenocarcinoma and large cell undifferentiated carcinoma
-
Holmes EC. Surgical adjuvant therapy for stage II and stage III adenocarcinoma and large cell undifferentiated carcinoma. Chest 106, 293S-296S (1994).
-
(1994)
Chest
, vol.106
, pp. 293S-296S
-
-
Holmes, E.C.1
-
52
-
-
0026653868
-
Interleukin-2 and interferon-α in the treatment of patients with advanced non-small cell lung cancer
-
Jansen RL, Slingerland R, Goey SH et al. Interleukin-2 and interferon-α in the treatment of patients with advanced non-small cell lung cancer. J. Immunother. 12, 70-73 (1992).
-
(1992)
J. Immunother.
, vol.12
, pp. 70-73
-
-
Jansen, R.L.1
Slingerland, R.2
Goey, S.H.3
-
53
-
-
79960110662
-
Randomized Phase III trial of paclitaxel/carboplatin with or without PF-3512676 (toll-like receptor 9 agonist) as first-line treatment for advanced non-small cell lung cancer
-
Hirsh V, Paz-Ares L, Boyer M et al. Randomized Phase III trial of paclitaxel/carboplatin with or without PF-3512676 (toll-like receptor 9 agonist) as first-line treatment for advanced non-small cell lung cancer. J. Clin. Oncol. 29, 2667-2674 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 2667-2674
-
-
Hirsh, V.1
Paz-Ares, L.2
Boyer, M.3
-
54
-
-
84855184648
-
A Phase III randomized study of gemcitabine and cisplatin with or without PF-3512676 (TLR9 agonist) as first-line treatment of advanced non-small cell lung cancer
-
Manegold C, Van Zandwijk N, Szczesna A et al. A Phase III randomized study of gemcitabine and cisplatin with or without PF-3512676 (TLR9 agonist) as first-line treatment of advanced non-small cell lung cancer. Ann. Oncol. 23, 72-77 (2012).
-
(2012)
Ann. Oncol.
, vol.23
, pp. 72-77
-
-
Manegold, C.1
Van Zandwijk, N.2
Szczesna, A.3
-
55
-
-
80755143443
-
Randomized, double-blind, placebo-controlled Phase II study of single-agent oral Talactoferrin in patients with locally advanced or metastatic non-small cell lung cancer that progressed after chemotherapy
-
Parikh PM, Vaid A, Advani SH et al. Randomized, double-blind, placebo-controlled Phase II study of single-agent oral Talactoferrin in patients with locally advanced or metastatic non-small cell lung cancer that progressed after chemotherapy. J. Clin. Oncol. 29, 4129-4136 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 4129-4136
-
-
Parikh, P.M.1
Vaid, A.2
Advani, S.H.3
-
56
-
-
79958111407
-
A randomized, double-blind, placebo-controlled, Phase II study of oral Talactoferrin in combination with carboplatin and paclitaxel in previously untreated locally advanced or metastatic non-small cell lung cancer
-
Digumarti R, Wang Y, Raman G et al. A randomized, double-blind, placebo-controlled, Phase II study of oral Talactoferrin in combination with carboplatin and paclitaxel in previously untreated locally advanced or metastatic non-small cell lung cancer. J. Thorac. Oncol. 6, 1098-1103 (2011).
-
(2011)
J. Thorac. Oncol.
, vol.6
, pp. 1098-1103
-
-
Digumarti, R.1
Wang, Y.2
Raman, G.3
-
57
-
-
84929848842
-
FORTIS-M, a randomized, double-blind, placebo-controlled Phase 3 study of oral Talactoferrin alfa with best supportive care in patients with advanced non-small cell lung cancer following two or more prior regimens-by the FORTIS-M study group
-
Ramalingam SS, Crawford J, Chang A et al. FORTIS-M, a randomized, double-blind, placebo-controlled Phase 3 study of oral Talactoferrin alfa with best supportive care in patients with advanced non-small cell lung cancer following two or more prior regimens-by the FORTIS-M study group. Ann. Oncol. 23(Suppl. 9), 2347 (2013).
-
(2013)
Ann. Oncol.
, vol.23
, pp. 2347
-
-
Ramalingam, S.S.1
Crawford, J.2
Chang, A.3
-
58
-
-
51349165526
-
CTLA4 blockade expands FoxP3+ regulatory and activated effector CD4+ T cells in a dose-dependent fashion
-
Kavanagh B, O'Brien S, Lee D et al. CTLA4 blockade expands FoxP3+ regulatory and activated effector CD4+ T cells in a dose-dependent fashion. Blood 112, 1175-1183 (2008).
-
(2008)
Blood
, vol.112
, pp. 1175-1183
-
-
Kavanagh, B.1
O'Brien, S.2
Lee, D.3
-
59
-
-
28244492012
-
Analysis of the cellular mechanism of antitumor responses and autoimmunity in patients treated with CTLA-4 blockade
-
Maker AV, Attia P, Rosenberg SA. Analysis of the cellular mechanism of antitumor responses and autoimmunity in patients treated with CTLA-4 blockade. J. Immunol. 175, 7746-7754 (2005).
-
(2005)
J. Immunol.
, vol.175
, pp. 7746-7754
-
-
Maker, A.V.1
Attia, P.2
Rosenberg, S.A.3
-
60
-
-
73149092567
-
Guidelines for the evaluation of immune therapy activity in solid tumors: Immune-related response criteria
-
Wolchok JD, Hoos A, O'Day S et al. Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria. Clin. Cancer Res. 15, 7412-7420 (2009).
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 7412-7420
-
-
Wolchok, J.D.1
Hoos, A.2
O'Day, S.3
-
61
-
-
84863911486
-
Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small cell lung cancer: Results from a randomized, double-blind, multicenter Phase II study
-
Lynch TJ, Bondarenko I, Luft A et al. Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small cell lung cancer: results from a randomized, double-blind, multicenter Phase II study. J. Clin. Oncol. 30, 2046-2055 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
, pp. 2046-2055
-
-
Lynch, T.J.1
Bondarenko, I.2
Luft, A.3
-
62
-
-
84871532643
-
Ipilimumab in combination with paclitaxel and carboplatin as first-line therapy in extensive-disease small cell lung cancer: Results from a randomized, double-blind, multicenter Phase 2 trial
-
Reck M, Bondarenko I, Luft A et al. Ipilimumab in combination with paclitaxel and carboplatin as first-line therapy in extensive-disease small cell lung cancer: results from a randomized, double-blind, multicenter Phase 2 trial. Ann. Oncol. 24, 75-83 (2013).
-
(2013)
Ann. Oncol.
, vol.24
, pp. 75-83
-
-
Reck, M.1
Bondarenko, I.2
Luft, A.3
-
64
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat. Rev. Cancer 12, 252-264 (2012).
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 252-264
-
-
Pardoll, D.M.1
-
65
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N. Engl. J. Med. 366, 2443-2454 (2012).
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
-
66
-
-
82155168544
-
A prospective Phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma
-
Hamid O, Schmidt H, Nissan A et al. A prospective Phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma. J. Transl. Med. 9, 204-209 (2011).
-
(2011)
J. Transl. Med.
, vol.9
, pp. 204-209
-
-
Hamid, O.1
Schmidt, H.2
Nissan, A.3
-
67
-
-
84929910389
-
Clinical activity and safety of anti-programmed death (PD-1) (BMS-936558/MDX-1106/ONO-4538) in patients (pts) with advanced non-small cell lung cancer (NSCLC)
-
Abstract 1237
-
Gettinger S, Antonia SJ, Spigel D et al. Clinical activity and safety of anti-programmed death (PD-1) (BMS-936558/MDX-1106/ONO-4538) in patients (pts) with advanced non-small cell lung cancer (NSCLC). Ann. Oncol. 23(Suppl. 9), Abstract 1237 (2013).
-
(2013)
Ann. Oncol.
, vol.23
-
-
Gettinger, S.1
Antonia, S.J.2
Spigel, D.3
-
68
-
-
84880710451
-
Nivolumab (anti-PD-1; BMS-936558; ONO-4538) in patients with advanced solid tumors: Survival and long-term safety in a Phase I trial
-
Abstract 3002
-
Topalian SL, Sznol M, Brahmer JR et al. Nivolumab (anti-PD-1; BMS-936558; ONO-4538) in patients with advanced solid tumors: survival and long-term safety in a Phase I trial. J. Clin. Oncol. 31, Abstract 3002 (2013).
-
(2013)
J. Clin. Oncol.
, vol.31
-
-
Topalian, S.L.1
Sznol, M.2
Brahmer, J.R.3
-
69
-
-
84877138564
-
Novel mechanism of synergistic effects of conventional chemotherapy and immune therapy of cancer
-
Ramakrishnan R, Gabrilovich DI. Novel mechanism of synergistic effects of conventional chemotherapy and immune therapy of cancer. Cancer Immunol. Immunother. 62, 405-410 (2013).
-
(2013)
Cancer Immunol. Immunother.
, vol.62
, pp. 405-410
-
-
Ramakrishnan, R.1
Gabrilovich, D.I.2
-
70
-
-
84875039618
-
Combining radiotherapy and cancer immunotherapy: A paradigm shift
-
Formenti SC, Demaria S. Combining radiotherapy and cancer immunotherapy: a paradigm shift. J. Natl. Cancer Inst. 105, 256-265 (2013).
-
(2013)
J. Natl. Cancer Inst.
, vol.105
, pp. 256-265
-
-
Formenti, S.C.1
Demaria, S.2
-
71
-
-
79957709717
-
Vaccines for the treatment of non-small cell lung cancer: Investigational approaches and clinical experience
-
Mellstedt H, Vansteenkiste J, Thatcher N. Vaccines for the treatment of non-small cell lung cancer: Investigational approaches and clinical experience. Lung Cancer 73, 11-17 (2011).
-
(2011)
Lung Cancer
, vol.73
, pp. 11-17
-
-
Mellstedt, H.1
Vansteenkiste, J.2
Thatcher, N.3
-
86
-
-
84929881353
-
-
Study of Nivolumab (BMS-936558) in Combination With Gemcitabine/Cisplatin, Pemetrexed/Cisplatin, Carboplatin/Paclitaxel, Bevacizumab Maintenance, Erlotinib, Ipilimumab or as Monotherapy in First-Line or in Switch Maintenance in Subjects With Stage IIIB/IV Non-small Cell Lung Cancer (NSCLC) (CheckMate 012). http://clinicaltrials.gov/ct2/show/NCT01454102?term=NCT01454102&rank=1
-
Study of Nivolumab (BMS-936558) in Combination with Gemcitabine/Cisplatin, Pemetrexed/Cisplatin, Carboplatin/Paclitaxel, Bevacizumab Maintenance, Erlotinib, Ipilimumab or as Monotherapy in First-Line or in Switch Maintenance in Subjects with Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) (CheckMate 012)
-
-
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