Too Sweet for Autophagy: Hexokinase Inhibition of mTORC1 Activates Autophagy

Molecular Cell

Volumn 53, Issue 4, 2014, Pages 517-518

  Kundu, Mondira ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; AUTOPHAGY; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCOSE; HEXOKINASE; MULTIPROTEIN COMPLEXES; MYOCYTES, CARDIAC; TOR SERINE-THREONINE KINASES;

EID: 84894038895     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.02.009     Document Type: Short Survey

References (10)

1. Bar-Peled L., Schweitzer L.D., Zoncu R., Sabatini D.M. Cell 2012, 150:1196-1208.
2. Dibble C.C., Manning B.D. Nat. Cell Biol. 2013, 15:555-564.
3. Efeyan A., Zoncu R., Chang S., Gumper I., Snitkin H., Wolfson R.L., Kirak O., Sabatini D.D., Sabatini D.M. Nature 2013, 493:679-683.
4. Haller J.F., Krawczyk S.A., Gostilovitch L., Corkey B.E., Zoeller R.A. Biochim. Biophys. Acta 2011, 1812:1393-1402.
5. Hariharan N., Ikeda Y., Hong C., Alcendor R.R., Usui S., Gao S., Maejima Y., Sadoshima J. PLoS ONE 2013, 8:e51632.
6. Inoki K., Kim J., Guan K.L. Annu. Rev. Pharmacol. Toxicol. 2012, 52:381-400.
7. Kim J., Kundu M., Viollet B., Guan K.L. Nat. Cell Biol. 2011, 13:132-141.
8. Morita M., Gravel S.P., Chénard V., Sikström K., Zheng L., Alain T., Gandin V., Avizonis D., Arguello M., Zakaria C., et al. Cell Metab. 2013, 18:698-711.
9. Roberts D.J., Tan-Sah V.P., Ding E.Y., Smith J.M., Miyamoto S. Mol. Cell 2014, 53:521-533. this issue.
10. Sen S., Kundu B.K., Wu H.C., Hashmi S.S., Guthrie P., Locke L.W., Roy R.J., Matherne G.P., Berr S.S., Terwelp M., et al. J Am Heart Assoc 2013, 2:e004796.