메뉴 건너뛰기




Volumn 68, Issue 2, 2014, Pages 419-425

Sphingosine Kinase-1 Activation Causes Acquired Resistance Against Sunitinib in Renal Cell Carcinoma Cells

Author keywords

ERK; Renal cell carcinoma; SK1; Sunitinib

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2-(2-AMINO-3-METHOXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; ANTINEOPLASTIC AGENT; FLAVONOID; INDOLE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOTRANSFERASE; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PYRROLE DERIVATIVE; SPHINGOSINE KINASE; SUNITINIB;

EID: 84893955445     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12013-013-9723-4     Document Type: Article
Times cited : (23)

References (35)
  • 1
    • 33846224397 scopus 로고    scopus 로고
    • The follow-up management of non-metastatic renal cell carcinoma: Definition of a surveillance protocol
    • Antonelli, A., et al. (2007). The follow-up management of non-metastatic renal cell carcinoma: Definition of a surveillance protocol. BJU International, 99(2), 296-300.
    • (2007) BJU International , vol.99 , Issue.2 , pp. 296-300
    • Antonelli, A.1
  • 3
    • 34548316976 scopus 로고    scopus 로고
    • Molecular basis for sunitinib efficacy and future clinical development
    • Faivre, S., et al. (2007). Molecular basis for sunitinib efficacy and future clinical development. Nature Reviews. Drug Discovery, 6(9), 734-745.
    • (2007) Nature Reviews. Drug Discovery , vol.6 , Issue.9 , pp. 734-745
    • Faivre, S.1
  • 4
    • 40549129373 scopus 로고    scopus 로고
    • Sunitinib versus interferon-alpha in metastatic renal-cell carcinoma
    • Irani, J. (2007). Sunitinib versus interferon-alpha in metastatic renal-cell carcinoma. Progres en Urologie, 17(5), 996.
    • (2007) Progres En Urologie , vol.17 , Issue.5 , pp. 996
    • Irani, J.1
  • 5
    • 35148857486 scopus 로고    scopus 로고
    • Sunitinib efficacy against advanced renal cell carcinoma
    • Motzer, R. J., et al. (2007). Sunitinib efficacy against advanced renal cell carcinoma. Journal of Urology, 178(5), 1883-1887.
    • (2007) Journal of Urology , vol.178 , Issue.5 , pp. 1883-1887
    • Motzer, R.J.1
  • 6
    • 76249133170 scopus 로고    scopus 로고
    • Interleukin-8 mediates resistance to antiangiogenic agent sunitinib in renal cell carcinoma
    • Huang, D., et al. (2010). Interleukin-8 mediates resistance to antiangiogenic agent sunitinib in renal cell carcinoma. Cancer Research, 70(3), 1063-1071.
    • (2010) Cancer Research , vol.70 , Issue.3 , pp. 1063-1071
    • Huang, D.1
  • 7
    • 0025813503 scopus 로고
    • Cellular adaptation in the origin and development of cancer
    • Farber, E., & Rubin, H. (1991). Cellular adaptation in the origin and development of cancer. Cancer Research, 51(11), 2751-2761.
    • (1991) Cancer Research , vol.51 , Issue.11 , pp. 2751-2761
    • Farber, E.1    Rubin, H.2
  • 8
    • 79953324725 scopus 로고    scopus 로고
    • Sphingosine kinase-1 enhances resistance to apoptosis through activation of PI3 K/Akt/NF-kappaB pathway in human non-small cell lung cancer
    • Song, L., et al. (2011). Sphingosine kinase-1 enhances resistance to apoptosis through activation of PI3 K/Akt/NF-kappaB pathway in human non-small cell lung cancer. Clinical Cancer Research, 17(7), 1839-1849.
    • (2011) Clinical Cancer Research , vol.17 , Issue.7 , pp. 1839-1849
    • Song, L.1
  • 9
    • 79956274055 scopus 로고    scopus 로고
    • Sphingosine kinase 1 overexpression is regulated by signaling through PI3K, AKT2, and mTOR in imatinib-resistant chronic myeloid leukemia cells
    • Marfe, G., et al. (2011). Sphingosine kinase 1 overexpression is regulated by signaling through PI3K, AKT2, and mTOR in imatinib-resistant chronic myeloid leukemia cells. Experimental Hematology, 39(6), 653-665.
    • (2011) Experimental Hematology , vol.39 , Issue.6 , pp. 653-665
    • Marfe, G.1
  • 10
    • 84893978357 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate (S1P) as a novel target in renal cancer (RCC)
    • Washington, DC: Cancer Research
    • Rupal S, B., et al. Sphingosine-1-phosphate (S1P) as a novel target in renal cancer (RCC). in AACR 101st Annual Meeting 2010. 2011. Washington, DC: Cancer Research.
    • (2011) AACR 101st Annual Meeting 2010
    • Rupal, S.B.1
  • 11
    • 67649185566 scopus 로고    scopus 로고
    • Activated Akt prevents antitumor activity of gefitinib in renal cancer cells
    • Kuroda, K., et al. (2009). Activated Akt prevents antitumor activity of gefitinib in renal cancer cells. Urology, 74(1), 209-215.
    • (2009) Urology , vol.74 , Issue.1 , pp. 209-215
    • Kuroda, K.1
  • 12
    • 77958058348 scopus 로고    scopus 로고
    • Synergistic antitumor activity of sorafenib in combination with epidermal growth factor receptor inhibitors in colorectal and lung cancer cells
    • Martinelli, E., et al. (2010). Synergistic antitumor activity of sorafenib in combination with epidermal growth factor receptor inhibitors in colorectal and lung cancer cells. Clinical Cancer Research, 16(20), 4990-5001.
    • (2010) Clinical Cancer Research , vol.16 , Issue.20 , pp. 4990-5001
    • Martinelli, E.1
  • 13
    • 83055198376 scopus 로고    scopus 로고
    • Antitumor activity of sorafenib in human cancer cell lines with acquired resistance to EGFR and VEGFR tyrosine kinase inhibitors
    • Morgillo, F., et al. (2011). Antitumor activity of sorafenib in human cancer cell lines with acquired resistance to EGFR and VEGFR tyrosine kinase inhibitors. PLoS One, 6(12), e28841.
    • (2011) PLoS One , vol.6 , Issue.12
    • Morgillo, F.1
  • 14
    • 79960344288 scopus 로고    scopus 로고
    • Sphingosine kinase 1 pathway is involved in melatonin-induced HIF-1alpha inactivation in hypoxic PC-3 prostate cancer cells
    • Cho, S. Y., et al. (2011). Sphingosine kinase 1 pathway is involved in melatonin-induced HIF-1alpha inactivation in hypoxic PC-3 prostate cancer cells. Journal of Pineal Research, 51(1), 87-93.
    • (2011) Journal of Pineal Research , vol.51 , Issue.1 , pp. 87-93
    • Cho, S.Y.1
  • 15
    • 78650874372 scopus 로고    scopus 로고
    • SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer
    • Abrams, T. J., et al. (2003). SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer. Molecular Cancer Therapeutics, 2(5), 471-478.
    • (2003) Molecular Cancer Therapeutics , vol.2 , Issue.5 , pp. 471-478
    • Abrams, T.J.1
  • 16
    • 33947504730 scopus 로고    scopus 로고
    • Sunitinib: from rational design to clinical efficacy
    • Chow, L. Q., & Eckhardt, S. G. (2007). Sunitinib: from rational design to clinical efficacy. Journal of Clinical Oncology, 25(7), 884-896.
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.7 , pp. 884-896
    • Chow, L.Q.1    Eckhardt, S.G.2
  • 17
    • 0037370498 scopus 로고    scopus 로고
    • A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
    • Rubinson, D. A., et al. (2003). A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nature Genetics, 33(3), 401-406.
    • (2003) Nature Genetics , vol.33 , Issue.3 , pp. 401-406
    • Rubinson, D.A.1
  • 18
    • 84855439199 scopus 로고    scopus 로고
    • Blocking the PI3K/AKT and MEK/ERK signaling pathways can overcome gefitinib-resistance in non-small cell lung cancer cell lines
    • Li, H., et al. (2011). Blocking the PI3K/AKT and MEK/ERK signaling pathways can overcome gefitinib-resistance in non-small cell lung cancer cell lines. Advances in Medical Sciences, 56(2), 275-284.
    • (2011) Advances in Medical Sciences , vol.56 , Issue.2 , pp. 275-284
    • Li, H.1
  • 19
    • 80054037863 scopus 로고    scopus 로고
    • Therapeutic potential of targeting sphingosine kinase 1 in prostate cancer
    • Pchejetski, D., et al. (2011). Therapeutic potential of targeting sphingosine kinase 1 in prostate cancer. Nature Reviews Urology, 8(10), 569-678.
    • (2011) Nature Reviews Urology , vol.8 , Issue.10 , pp. 569-678
    • Pchejetski, D.1
  • 20
    • 76249126867 scopus 로고    scopus 로고
    • Sunitinib acts primarily on tumor endothelium rather than tumor cells to inhibit the growth of renal cell carcinoma
    • Huang, D., et al. (2010). Sunitinib acts primarily on tumor endothelium rather than tumor cells to inhibit the growth of renal cell carcinoma. Cancer Research, 70(3), 1053-1062.
    • (2010) Cancer Research , vol.70 , Issue.3 , pp. 1053-1062
    • Huang, D.1
  • 21
    • 83755173017 scopus 로고    scopus 로고
    • Imaging guided trials of the angiogenesis inhibitor sunitinib in mouse models predict efficacy in pancreatic neuroendocrine but not ductal carcinoma
    • Olson, P., et al. (2011). Imaging guided trials of the angiogenesis inhibitor sunitinib in mouse models predict efficacy in pancreatic neuroendocrine but not ductal carcinoma. Proceedings of the National Academy of Sciences of the United States of America, 108(49), E1275-E1284.
    • (2011) Proceedings of the National Academy of Sciences of the United States of America , vol.108 , Issue.49
    • Olson, P.1
  • 22
    • 79952280877 scopus 로고    scopus 로고
    • Sunitinib and other targeted therapies for renal cell carcinoma
    • Powles, T., et al. (2011). Sunitinib and other targeted therapies for renal cell carcinoma. British Journal of Cancer, 104(5), 741-745.
    • (2011) British Journal of Cancer , vol.104 , Issue.5 , pp. 741-745
    • Powles, T.1
  • 23
    • 12244301581 scopus 로고    scopus 로고
    • In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship
    • Mendel, D. B., et al. (2003). In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship. Clinical Cancer Research, 9(1), 327-337.
    • (2003) Clinical Cancer Research , vol.9 , Issue.1 , pp. 327-337
    • Mendel, D.B.1
  • 24
    • 0041672482 scopus 로고    scopus 로고
    • SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models
    • Schueneman, A. J., et al. (2003). SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models. Cancer Research, 63(14), 4009-4016.
    • (2003) Cancer Research , vol.63 , Issue.14 , pp. 4009-4016
    • Schueneman, A.J.1
  • 25
    • 79956076053 scopus 로고    scopus 로고
    • Sunitinib suppresses tumor growth and metastases in a highly metastatic mouse mammary cancer model
    • Tanaka, Y., et al. (2011). Sunitinib suppresses tumor growth and metastases in a highly metastatic mouse mammary cancer model. Anticancer Research, 31(4), 1225-1234.
    • (2011) Anticancer Research , vol.31 , Issue.4 , pp. 1225-1234
    • Tanaka, Y.1
  • 26
    • 33750611016 scopus 로고    scopus 로고
    • The activity of sunitinib against gastrointestinal stromal tumor seems to be distinct from its antiangiogenic effects
    • Seandel, M., et al. (2006). The activity of sunitinib against gastrointestinal stromal tumor seems to be distinct from its antiangiogenic effects. Clinical Cancer Research, 12(20 Pt 1), 6203-6204.
    • (2006) Clinical Cancer Research , vol.12 , Issue.20 Pt 1 , pp. 6203-6204
    • Seandel, M.1
  • 27
    • 38449097166 scopus 로고    scopus 로고
    • Antiangiogenic and anti-invasive effects of sunitinib on experimental human glioblastoma
    • de Bouard, S., et al. (2007). Antiangiogenic and anti-invasive effects of sunitinib on experimental human glioblastoma. Neuro-Oncology, 9(4), 412-423.
    • (2007) Neuro-Oncology , vol.9 , Issue.4 , pp. 412-423
    • de Bouard, S.1
  • 28
    • 65549129226 scopus 로고    scopus 로고
    • Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells
    • Xin, H., et al. (2009). Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells. Cancer Research, 69(6), 2506-2513.
    • (2009) Cancer Research , vol.69 , Issue.6 , pp. 2506-2513
    • Xin, H.1
  • 29
    • 7944220649 scopus 로고    scopus 로고
    • Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2
    • Oliner, J., et al. (2004). Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2. Cancer Cell, 6(5), 507-516.
    • (2004) Cancer Cell , vol.6 , Issue.5 , pp. 507-516
    • Oliner, J.1
  • 30
    • 17444373925 scopus 로고    scopus 로고
    • Inhibition of angiogenic activity of renal carcinoma by an antisense oligonucleotide targeting fibroblast growth factor-2
    • Cenni, E. (2005). Inhibition of angiogenic activity of renal carcinoma by an antisense oligonucleotide targeting fibroblast growth factor-2. Anticancer Research, 25(2A), 1109-1113.
    • (2005) Anticancer Research , vol.25 , Issue.2 A , pp. 1109-1113
    • Cenni, E.1
  • 31
    • 47949099628 scopus 로고    scopus 로고
    • Modes of resistance to anti-angiogenic therapy
    • Bergers, G., & Hanahan, D. (2008). Modes of resistance to anti-angiogenic therapy. Nature Reviews Cancer, 8(8), 592-603.
    • (2008) Nature Reviews Cancer , vol.8 , Issue.8 , pp. 592-603
    • Bergers, G.1    Hanahan, D.2
  • 32
    • 77953671696 scopus 로고    scopus 로고
    • Activation of sphingosine kinase-1 in cancer: implications for therapeutic targeting
    • Cuvillier, O., et al. (2010). Activation of sphingosine kinase-1 in cancer: implications for therapeutic targeting. Current Molecular Pharmacology, 3(2), 53-65.
    • (2010) Current Molecular Pharmacology , vol.3 , Issue.2 , pp. 53-65
    • Cuvillier, O.1
  • 33
    • 77953966511 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate and cancer
    • Pyne, N. J., & Pyne, S. (2010). Sphingosine 1-phosphate and cancer. Nature Reviews Cancer, 10(7), 489-503.
    • (2010) Nature Reviews Cancer , vol.10 , Issue.7 , pp. 489-503
    • Pyne, N.J.1    Pyne, S.2
  • 34
    • 70349669267 scopus 로고    scopus 로고
    • Interaction of the multikinase inhibitors sorafenib and sunitinib with solute carriers and ATP-binding cassette transporters
    • Hu, S., et al. (2009). Interaction of the multikinase inhibitors sorafenib and sunitinib with solute carriers and ATP-binding cassette transporters. Clinical Cancer Research, 15(19), 6062-6069.
    • (2009) Clinical Cancer Research , vol.15 , Issue.19 , pp. 6062-6069
    • Hu, S.1
  • 35
    • 59649129538 scopus 로고    scopus 로고
    • Sunitinib (Sutent, SU11248), a small-molecule receptor tyrosine kinase inhibitor, blocks function of the ATP-binding cassette (ABC) transporters P-glycoprotein (ABCB1) and ABCG2
    • Shukla, S., et al. (2009). Sunitinib (Sutent, SU11248), a small-molecule receptor tyrosine kinase inhibitor, blocks function of the ATP-binding cassette (ABC) transporters P-glycoprotein (ABCB1) and ABCG2. Drug Metabolism and Disposition, 37(2), 359-365.
    • (2009) Drug Metabolism and Disposition , vol.37 , Issue.2 , pp. 359-365
    • Shukla, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.