Identification of the Minimum Effective Dose for Normally Distributed Endpoints Using a Model Selection Approach

Statistics in Biopharmaceutical Research

Volumn 6, Issue 1, 2014, Pages 55-66

  Kuiper, Rebecca M ^a   Gerhard, Daniel ^b   Hothorn, Ludwig A ^b  

^a UTRECHT UNIVERSITY   (Netherlands)

^b LEIBNIZ UNIVERSITY HANNOVER   (Germany)

Author keywords

Analysis of variance; GORIC; LOAEL; MED; Optimal dose; Order restrictions

Indexed keywords

ANALYSIS OF VARIANCE; ARTICLE; COMPUTER PROGRAM; CRITERION RELATED VALIDITY; DOSE CALCULATION; DOSE RESPONSE; DUNNETT TEST; GENERALIZED ORDER RESTRICTED INFORMATION CRITERION; MINIMUM EFFECTIVE DOSE; MODEL SELECTION APPROACH; NULL HYPOTHESIS; PHARMACOLOGICAL PARAMETERS; RISK ASSESSMENT; SAMPLE SIZE; SIMULATION; STATISTICAL ANALYSIS; STATISTICAL CONCEPTS; STATISTICAL SIGNIFICANCE; WILLIAMS TEST;

EID: 84893947561     PISSN: None     EISSN: 19466315     Source Type: Journal    
DOI: 10.1080/19466315.2013.847384     Document Type: Article

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