Optimizing drug therapy in patients with advanced dementia: A patient-centered approach

European Geriatric Medicine

Volumn 5, Issue 1, 2014, Pages 66-71

  Molist Brunet, N ^a   Sevilla Sanchez D ^b   Amblas Novellas J ^a   Codina Jane C ^b   Gomez Batiste X ^c   McIntosh, J ^d   Espaulella Panicot, J ^a  

^a Hospital de la Santa Creu   (Spain)

^b HOSPITAL GENERAL DE VIC   (Spain)

^c UNIVERSITY OF VIC CENTRAL UNIVERSITY OF CATALONIA   (Spain)

^d HOSPITAL CLÍNIC   (Spain)

Author keywords

Advanced dementia; End of life care; Polypharmacy

Indexed keywords

EID: 84893921805     PISSN: 18787649     EISSN: 18787657     Source Type: Journal    
DOI: 10.1016/j.eurger.2013.10.011     Document Type: Article

References (27)

1. World Health Organization National Institute on Aging, and National Institute of Health Global Health and Aging 2011 http://www.who.int/ageing/ publications/global-health/en/index.html. Accessed May 2013
2. K. Thomas et al. Prognostic Indicator Guidance 4th Ed. The Gold Standards Framework Centre in End of Life Care 2011 13 2012 http://www. goldstandardsframework.org.uk/LibraryofResourcesPresentationsandLinks.html. Accessed December
3. S.L. Mitchell, D.K. Kiely, and M.B. Hamel Dying with advanced dementia in the nursing home Arch Intern Med 164 3 2004 321 326
4. R. Lopez Mongil, J.A. Lopez Trigo, F.J. Castrodeza Sanz, S. Tamames Gomez, T. Leon Colombo Grupo de Trabajo de Atencion Sanitaria en Residencias de Ancianos de la Sociedad Espanola de Geriatria y G [Prevalence of dementia in institutionalized patients. The RESYDEM study] Rev Esp Geriatr Gerontol 44 1 2009 5 11
5. D. Gnjidic, S.N. Hilmer, and F.M. Blyth et al. Polypharmacy cutoff and outcomes: five or more medicines were used to identify community-dwelling older men at risk of different adverse outcomes J Clin Epidemiol 65 9 2012 989 995
6. S. Hall World Health Organization Regional Office for Europe Palliative care for older people: better practices 2011 World Health Organization, Regional Office for Europe Copenhagen, Denmark
7. M. Maltoni, E. Scarpi, and M. Rosati et al. Palliative sedation in end-of-life care and survival: a systematic review J Clin Oncol 30 12 2012 1378 1383
8. A. Qaseem, V. Snow, and P. Shekelle et al. Evidence-based interventions to improve the palliative care of pain, dyspnea, and depression at the end of life: a clinical practice guideline from the American College of Physicians Ann Intern Med 148 2 2008 141 146
9. P. Crome, F. Lally, and A. Cherubini et al. Exclusion of older people from clinical trials: professional views from nine European countries participating in the PREDICT study Drugs Aging 28 8 2011 667 677
10. H.M. Holmes, D.C. Hayley, G.C. Alexander, and G.A. Sachs Reconsidering medication appropriateness for patients late in life Arch Intern Med 166 6 2006 605 609
11. S.L. Mitchell, B.S. Black, and M. Ersek et al. Advanced dementia: state of the art and priorities for the next decade Ann Intern Med 156 1 Pt 1 2012 45 51
12. D. Le Couteur, E. Banks, and D.A.M. Gnjidic Deprescribing Aust Prescr 34 2011 182 185
13. Z.A. Marcum, M.E. Amuan, and J.T. Hanlon et al. Prevalence of unplanned hospitalizations caused by adverse drug reactions in older veterans J Am Geriatr Soc 60 1 2012 34 41
14. K.A. Hartholt, N. van der Velde, and C.W. Looman et al. Adverse drug reactions related hospital admissions in persons aged 60 years and over. The Netherlands, 1981-2007: less rapid increase, different drugs PLoS One 5 11 2010 e13977
15. D. O'Mahony, and M.N. O'Connor Pharmacotherapy at the end-of-life Age Ageing 40 4 2011 419 422
16. G.D. Schiff, W.L. Galanter, J. Duhig, A.E. Lodolce, M.J. Koronkowski, and B.L. Lambert Principles of conservative prescribing Arch Intern Med 171 16 2011 1433 1440
17. A.J. Cruz-Jentoft, B. Boland, and L. Rexach Drug therapy optimization at the end of life Drugs Aging 29 6 2012 511 521
18. D.B. Reuben, and M.E. Tinetti Goal-oriented patient care - an alternative health outcomes paradigm Engl N J Med 366 9 2012 777 779
19. K. Boyd, and S.A. Murray Recognising and managing key transitions in end of life care BMJ 341 2010 c4863
20. D. Garfinkel, S. Zur-Gil, and J. Ben-Israel The war against polypharmacy: a new cost-effective geriatric-palliative approach for improving drug therapy in disabled elderly people Isr Med Assoc J 9 6 2007 430 434
21. D. Garfinkel, and D. Mangin Feasibility study of a systematic approach for discontinuation of multiple medications in older adults: addressing polypharmacy Arch Intern Med 170 18 2010 1648 1654
22. C. Beer, P.I. loh, Y.G. Peng, and K.A.M. Potter A pilot randomized controlled trial of deprescribing Ther Adv Drug Safe 2 2011 37 43
23. E.A. Coleman, and R.A. Berenson Lost in transition: challenges and opportunities for improving the quality of transitional care Ann Intern Med 141 7 2004 533 536
24. G. Martin, and M. Sabbagh Palliative Care for Advanced Alzheimer's and Dementia 2010 Springer Publishing Company New York http://JHU.eblib.com/patron/ FullRecord.aspx?p=667355
25. X. Gómez-Batiste, M. Martínez-Muñoz, C. Blay, J. Amblàs, and L. Vila et al. CXe. Identifyung patients with chronic conditions in need of palliative care in the general population: development of the NECPAL tool and preliminary prevalence rates in Catalonia BMJ Support Palliat Care 2013 10.1136/bmjspcare-2012-000211
26. American Geriatrics Society Beers Criteria Update Expert P. American Geriatrics Society updated Beers Criteria for potentially inappropriate medication use in older, adults J Am Geriatr Soc 60 4 2012 616 631
27. P. Gallagher, C. Ryan, S. Byrne, J. Kennedy, and D. O'Mahony STOPP (Screening Tool of Older Person's Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment). Consensus validation Int J Clin Pharmacol Ther 46 2 2008 72 83