Pharmacotherapy at the end-of-life

Age and Ageing

Volumn 40, Issue 4, 2011, Pages 419-422

  O'mahony, Denis ^a   O'connor, Marie N ^a  

^a University College Cork and INFANT Centre   (Ireland)

Author keywords

Elderly; End of life; Pharmacotherapy

Indexed keywords

DRUG CLASSIFICATION; DRUG USE; DRUG UTILIZATION; GERIATRIC ASSESSMENT; HUMAN; NOTE; PATIENT IDENTIFICATION; POLYPHARMACY; PRIORITY JOURNAL; TERMINAL CARE; TREATMENT WITHDRAWAL;

AGED; AGED, 80 AND OVER; AGING; DRUG THERAPY; EVIDENCE-BASED MEDICINE; FRAIL ELDERLY; HUMANS; INAPPROPRIATE PRESCRIBING; LIFE EXPECTANCY; PALLIATIVE CARE; PATIENT SELECTION; POLYPHARMACY; PRACTICE GUIDELINES AS TOPIC; RISK ASSESSMENT; SECONDARY PREVENTION;

EID: 79959551986     PISSN: 00020729     EISSN: 14682834     Source Type: Journal    
DOI: 10.1093/ageing/afr059     Document Type: Note

References (17)

1. Cherubini A, Del Signore S, Ouslander J, Semla T, Michel JP. Fighting against age discrimination in clinical trials. J Am Geriatr Soc 2010; 58: 1791-7.
2. Holmes HM, Hayley DC, Alexander CG, Sachs GA. Reconsidering medication appropriateness for patients late in life. Arch Intern Med 2006; 166: 605-9.
3. Routledge PA, O'Mahony MS, Woodhouse KW. Adverse drug reactions in elderly patients. Br J Clin Pharmacol 2004; 57: 121-6.
4. Hanlon JT, Pieper CF, Hajjar ER, Sloane RJ, Lindblad CI, Ruby CM et al. Incidence and predictors of all and preventable adverse drug reactions in frail elderly persons after hospital stay. J Gerontol A Biol Sci Med Sci 2006; 61: 511-5.
5. Hughes CM. Medication non-adherence in the elderly: how big is the problem? Drugs Aging 2004; 21: 793-811.
6. Medication Use Review: www.npa.co.uk/information-service.
7. Fick DM, Cooper JW, Wade WE, Waller JL, Maclean JR, Beers MH. Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. Arch Intern Med 2003; 163: 2716-24.
8. Onder G, Landi F, Liperoti R, Fialova D, Gambassi G, Bernabei R. Impact of inappropriate drug use among hospitalized older adults. Eur J Clin Pharmacol 2005; 61: 453-9.
9. Laroche ML, Charmes JP, Nouaille Y, Picard N, Merle L. Is inappropriate medication use a major cause of adverse drug reactions in the elderly? Br J Clin Pharmacol 2007; 63: 177-86.
10. Gallagher P, Ryan C, Byrne S, Kennedy J, O'Mahony D. STOPP (Screening Tool of Older Person's Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment). Consensus validation. Int J Clin Pharmacol Ther 2008; 46: 72-83.
11. Gallagher P, O'Mahony D. STOPP (Screening Tool of Older Persons' potentially inappropriate Prescriptions): application to acutely ill elderly patients and comparison with Beers' criteria (original article). Age Ageing 2008; 37: 673-9.
12. Blass DM, Black BS, Phillips H, Finucane T, Baker A, Loreck D et al. Medication use in nursing home residents with advanced dementia. Int J Geriatr Psychiatry 2008; 23: 490-6.
13. Merle L, Laroche ML, Dantoine T, Charmes JP. Predicting and preventing adverse drug reactions in the very old. Drugs Aging 2005; 22: 375-92.
14. Onder G, Petrovic M, Tangiisuran B, Meinardi MC, Markito-Notenboom WP, Somers A et al. Development and validation of a score to assess risk of adverse drug reactions among in-hospital patients 65years or older: the GerontoNet ADR risk score. Arch Intern Med 2010; 170: 1142-8.
15. Garfinkel D, Zur-Gil S, Ben-Israel J. The war against polypharmacy: a new cost-effective geriatric-palliative approach for improving drug therapy in disabled elderly people. Isr Med Assoc J 2007; 9: 430-4.
16. Garfinkel D, Mangin D. Feasibility study of a systematic approach for discontinuation of multiple medications in older adults: addressing polypharmacy. Arch Intern Med 2010; 170: 1648-1654.
17. Telson L, Barry M. Recent developments in pharmacoeconomic evaluation in Ireland. Expert Rev Pharmacoecon Outcomes Res 2010; 10: 221-224.