In vitro Gd-DTPA relaxometry studies in oxygenated venous human blood and aqueous solution at 3 and 7T

Contrast Media and Molecular Imaging

Volumn 9, Issue 2, 2014, Pages 169-176

  Kalavagunta, Chaitanya ^a   Michaeli, Shalom ^a   Metzger, Gregory J ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Aqueous solution; Arterial blood; Gd DTPA; Oxygenation; Relaxivity; Relaxometry; T1; T2*

Indexed keywords

AQUEOUS SOLUTION; ARTERIAL BLOOD; GD-DTPA; OXYGENATION; RELAXIVITY; RELAXOMETRY; T1; T2*;

CONTRAST MEDIA; GADOLINIUM DTPA; HUMANS; MAGNETIC FIELDS; MAGNETIC RESONANCE IMAGING; OXYGEN;

EID: 84893871717     PISSN: 15554309     EISSN: 15554317     Source Type: Journal    
DOI: 10.1002/cmmi.1568     Document Type: Article

References (18)

1. Parker GJ, Roberts C, Macdonald A, Buonaccorsi GA, Cheung S, Buckley DL, Jackson A, Watson Y, Davies K, Jayson GC. Experimentally-derived functional form for a population-averaged high-temporal-resolution arterial input function for dynamic contrast-enhanced MRI. Magn Reson Med 2006; 56(5): 993-1000.
2. 2* effects on DCE-MRI of the prostate at 7T. Proc Int Soc Mag Reson Med 2009; 17: 4369.
3. Umutlu L, Maderwald S, Kinner S, Kraff O, Bitz AK, Orzada S, Johst S, Wrede K, Forsting M, Ladd ME, Lauenstein TC, Quick HH. First-pass contrast-enhanced renal MRA at 7 Tesla: initial results. Eur Radiol 2013; 23(4): 1059-1066.
4. Zhang H, Xie Y. Efficiency of paramagnetic relaxation enhancement in off-resonance rotating frame. J Magn Reson 2006; 181(2): 212-222.
5. Rinck PA. Magnetic Resonance in Medicine: The Basic Textbook of the European Magnetic Resonance Forum. Wiley-Blackwell: Chichester, 2001.
6. Trulock E. Clinical Methods: The History, Physical, and Laboratory Examinations, Walker HKHW and Hurst JW (eds), 3rd edn. Butterworths: Boston, MA, 1990.
7. Scott PV, Horton JN, Mapleson WW. Leakage of oxygen from blood and water samples stored in plastic and glass syringes. Br Med J 1971; 3(5773): 512-516.
8. 2, and chemical-shift imaging. Magn Reson Med 1990; 13(1): 77-89.
9. Barth M, Moser E. Proton NMR relaxation times of human blood samples at 1.5T and implications for functional MRI. Cell Mol Biol 1997; 43(5): 783-791.
10. 2* estimation. Magn Reson Med 1998; 39(5): 685-690.
11. 2* relaxivities of human whole blood to ProHance, Vasovist, and deoxyhemoglobin. Magn Reson Med 2008; 60(6): 1313-1320.
12. Thulborn KR, Waterton JC, Matthews PM, Radda GK. Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field. Biochim Biophys Acta 1982; 714(2): 265-270.
13. Li X, Springer CS Jr, Jerosch-Herold M. First-pass dynamic contrast-enhanced MRI with extravasating contrast reagent: evidence for human myocardial capillary recruitment in adenosine-induced hyperemia. NMR Biomede 2009; 22(2): 148-157.
14. 1 relaxation time in vitro. Acad Radiol 2003; 10(8): 854-860.
15. 2 measurements of the MR imaging contrast agents Gd-DTPA and Gd-DTPA BMA at 1.5T. Eur Radiol 1997; 7(2): 264-274.
16. Rohrer M, Bauer H, Mintorovitch J, Requardt M, Weinmann H-J. Comparison of magnetic properties of MRI contrast media solutions at different magnetic field strengths. Invest Radiol 2005; 40(11): 715-724.
17. Rozijn T, van der Sanden B, Heerschap A, Creyghton J, Bovee W. Determination of in vivo rat muscle Gd-DTPA relaxivity at 6.3 T. Magn Reson Mater Phys Biol Med 1999; 9(1): 65-71.
18. Tan CX. Dynamic water proton relaxation in human venous blood following double Gd-DTPA administrations at 1.5 T correlated with intra-vascular contribution in BOLD fMRI. Proc Int Soc Mag Reson Med 1999; 7: 1191.