First-pass dynamic contrast-enhanced MRI with extravasating contrast reagent: Evidence for human myocardial capillary recruitment in adenosine-induced hyperemia

NMR in Biomedicine

Volumn 22, Issue 2, 2009, Pages 148-157

  Li, Xin ^a   Springer Jr , Charles S ^a   Jerosch Herold, Michael ^b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Contrast reagent; Equilibrium water exchange; Flow; Myocardial perfusion; Permeation

Indexed keywords

CAPILLARY BLOOD; CONTRAST REAGENT; DYNAMIC CONTRAST ENHANCED MRI; EQUILIBRIUM WATER EXCHANGE; FLOW; GD-DTPA; INTRACELLULAR WATER; INTRAVASCULAR; MODEL ANALYSIS; MYOCARDIAL PERFUSION; NOISY DATA; PERMEABILITY COEFFICIENTS; PSEUDO-FIRST-ORDER RATE CONSTANT; SENSITIVE PARAMETER; SURFACE AREA; VOLUME FLOW; WATER EXCHANGE;

EMPLOYMENT; GADOLINIUM; WINDOWS;

RATE CONSTANTS;

ADENOSINE; GADOLINIUM PENTETATE; CONTRAST MEDIUM; DIAGNOSTIC AGENT;

ADULT; AGED; ANALYTICAL PARAMETERS; ARTICLE; BLOOD VOLUME; BLOOD VOLUME FRACTION; CAPILLARY FLOW; CAPILLARY PERMEABILITY; CONTRAST ENHANCEMENT; CONTROLLED STUDY; CORONARY ARTERY DILATATION; DIFFUSION COEFFICIENT; DRUG ABSORPTION; DRUG DISTRIBUTION; DRUG PENETRATION; EQUILIBRIUM CONSTANT; FLOW KINETICS; HEART MUSCLE BLOOD FLOW; HEART MUSCLE CAPILLARY; HUMAN; HUMAN EXPERIMENT; HYDRODYNAMICS; HYPEREMIA; MATHEMATICAL ANALYSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PERMEABILITY COEFFICIENT SURFACE AREA PRODUCT; PRIORITY JOURNAL; BIOLOGICAL MODEL; CLINICAL TRIAL; COMPUTER ASSISTED DIAGNOSIS; COMPUTER SIMULATION; CONTRAST MEDIUM EXTRAVASATION; CONTROLLED CLINICAL TRIAL; FEMALE; HEART; HEART MUSCLE; HISTOLOGY; MALE; METABOLISM; METHODOLOGY; MIDDLE AGED; RANDOMIZED CONTROLLED TRIAL; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

ADENOSINE; AGED; AGED, 80 AND OVER; CAPILLARY PERMEABILITY; COMPUTER SIMULATION; CONTRAST MEDIA; EXTRAVASATION OF DIAGNOSTIC AND THERAPEUTIC MATERIALS; FEMALE; GADOLINIUM DTPA; HEART; HUMANS; HYPEREMIA; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MALE; MIDDLE AGED; MODELS, CARDIOVASCULAR; MYOCARDIUM; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 64549160331     PISSN: 09523480     EISSN: 10991492     Source Type: Journal    
DOI: 10.1002/nbm.1293     Document Type: Article

References (44)

1. Al-Saadi N, Nagel E, Gross M, Bornstedt A, Schnackenburg B, Klein C, Klimek W, Oswald H, Fleck E. Noninvasive detection of myocardial ischemia from perfusion reserve based on cardiovascular magnetic resonance. Circulation 2000; 101(12): 1379-1383.
2. Kahler E, Waller C, Rommel E, Hiller KH, Voll S, Broich A, Hu K, Schnackerz KD, Bauer WR, Ertl G, Haase A. Quantitative regional blood volume studies in rat myocardium in vivo. Magn Reson Med 1998; 40(4): 517-525.
3. Bjomerud A, Bjerner T, Johansson LO, Ahlstrom HK. Assessment of myocardial blood volume and water exchange: theoretical considerations and in vivo results. Magn Reson Med 2003; 49(5): 828-837.
4. Judd RM, Reeder SB, May-Newman K. Effects of water exchange on the measurement of myocardial perfusion using paramagnetic contrast agents. Magn Reson Med 1999; 41(2): 334-342.
5. Patel PP, Koppenhafer SL, Scholz TD. Measurement of kinetic perfusion parameters of gadoteridol in intact myocardium: effects of ischemia/ reperfusion and coronary vasodilation. Magnetic Resonance Imaging 1995; 13(6): 799-806.
6. Diesbourg LD, Prato FS, Wisenberg G, Drost DJ, Marshall TP, Carroll SE, O'Neill B. Quantification of myocardial blood flow and extracellular volumes using a bolus injection of Gd-DTPA: kinetic modeling in canine ischemic disease. Magn Reson Med 1992; 23(2): 239-253.
7. Bellamy DD, Pereira RS, McKenzie CA, Prato FS, Drost DJ, Sykes J, Wisenberg G. Gd-DTPA bolus tracking in the myocardium using T1 fast acquisition relaxation mapping (T1 FARM). Magn Reson Med 2001; 46(3): 555-564.
8. Wang L, Jerosch-Herold M, Jacobs DR Jr, Shahar E, Folsom AR. Coronary risk factors and myocardial perfusion in asymptomatic adults: the Multi-Ethnic Study of Atherosclerosis (MESA). J. Am Coll Cardiol 2006; 47(3): 565-572.
9. Li X, Rooney WD, Springer CS. A unified magnetic resonance imaging pharmacokinetic theory: intravascular and extracellular contrast reagents. Magn Reson Med 2005; 54(6): 1351-1359. [Erratum: Magn Reson Med 2006; 55:1217.]
10. Jerosch-Herold M, Swingen C, Seethamraju RT. Myocardial blood flow quantification with MRI by model-independent deconvolution. Med Phys 2002; 29(5): 886-897.
11. Kroll K, Wilke N, Jerosch-Herold M, Wang Y, Zhang Y, Bache RJ, Bassingthwaighte JB. Modeling regional myocardial flows from residue functions of an intravascular indicator. Am J Physiol 1996; 271 (4 Pt 2): H1643-H1655.
12. Zierler KL. Theoretical basis of indicator-dilution methods for measuring flow and volume. Circ Res 1962; 10: 393-407.
13. Wang L, Jerosch-Herold M, Jacobs DR Jr, Shahar E, Detrano R, Folsom AR. Coronary artery calcification and myocardial perfusion in asymptomatic adults: the MESA (Multi-Ethnic Study of Atherosclerosis). J. Am Coll Cardiol 2006; 48(5): 1018-1026.
14. Jerosch-Herold M, Wilke N, Stillman AE, Wilson RF. Magnetic resonance quantification of themyocardial perfusion reserve with a Fermi function model for constrained deconvolution. Med Phys 1998; 25(1): 73-84.
15. Tofts PS, Brix G, Buckley DL, Evelhoch JL, Henderson E, Knopp MV, Larsson HB, Lee TY, Mayr NA, Parker GJ, Port RE, Taylor J, Weisskoff RM. Estimating kinetic parameters from dynamic contrast-enhanced T(1)-weighted MRI of a diffusable tracer: standardized quantities and symbols. J. Magn Reson Imaging 1999; 10(3): 223-232.
16. Bevington PR. Data Reduction and Error Analysis for the Physical Sciences. McGraw-Hill: New York, 1969.
17. Renkin EM. Transport of potassium-42 from blood to tissue in isolated mammalian skeletal muscles. Am J Physiol 1959; 197: 1205-1210.
18. Crone C. The permeability of capillaries in various organs as determined by use of the 'indicator diffusion' method. Acta Physiol Scand 1963; 58: 292-305.
19. Yankeelov TE, Rooney WD, Li X, Springer CS. Variation of the relaxo-graphic "shutter-speed" for transcytolemmalwater exchange affects the CR bolus-tracking curve shape. Magn Reson Med 2003; 50(6): 1151-1169.
20. Li X, Springer CS, Jerosch-Herold M. Parametric aspects of first pass DCE MRI myocardial studies. Proceedings of the 14th Annual Meeting ISMRM, Seattle, USA. 2006; 1165.
21. Li X, Rooney WD, Springer CS. Intercompartmental Water Exchange Effects in DCE MRI. Proceedings of the 14th Annual Meeting ISMRM, Seattle, USA. 2006; 1530.
22. Li X, Rooney WD, Springer CS. Quantitative aspects of measuring contrast reagent extravasation in the healthy human brain. Proceedings of the 14th Annual Meeting ISMRM, Seattle, USA. 2006; 2650.
23. Möhlenkamp S, Lerman LO, Lerman A, Behrenbeck TR, Katusic ZS, Sheedy PF. 2nd, Ritman EL. Minimally invasive evaluation of coronary microvascular function by electron beam computed tomography. Circulation 2000; 102(19): 2411-2416.
24. Fritz-Hansen T, Larsson HB, Rostrup E, Sondergaard L, Ring P, Henrikson O. Quantification of myocardial perfusion at rest and during dipyridamole infusion in humans. Proceedings of the 3rd Annual Meeting ISMRM, Nice, France. 1995; 21.
25. Cullen JH, Horsfield MA, Reek CR, Cherryman GR, Barnett DB, Samani NJ. A myocardial perfusion reserve index in humans using first-pass contrast-enhanced magnetic resonance imaging. J. Am Coll Cardiol 1999; 33(5): 1386-1394.
26. Li X, Kohama SG, Hobbs TR, Rooney WD, Jerosch-Herold M, Springer CS. 3T MRI detection of contrast reagent extravasation in the normal primate brain. Proceedings of the 15th Annual Meeting ISMRM, Berlin, Germany. 2007; 1434.
27. Rooney WD, Telang F, Springer CS. Quantitative 4T determination of normal human brain vascular properties suggests CR transport across BBB. Proceedings of the 10th Annual Meeting ISMRM, Honolulu, HI, USA. 2002; 1314.
28. Möhlenkamp S, Lerman LO, Bajzer Z, Lund PE, Ritman EL. Quantification of myocardial microcirculatory function with X-ray CT. Ann N Y Acad Sci 2002; 972: 307-316.
29. Donahue KM, Weisskoff RM, Burstein D. Water diffusion and exchange as they influence contrast enhancement. J. Magn Reson Imaging 1997; 7(1): 102-110.
30. Tofts PS. Modeling tracer kinetics in dynamic Gd-DTPA MR imaging. J. Magn Reson Imaging 1997; 7(1): 91-101.
31. Wiart M, Carme S, Mai W, Larsson HB, Neyran B, Canet-Soulas E. In vivo quantification of regional myocardial blood flow: validity of the fast-exchange approximation for intravascular T1 contrast agent and long inversion time. Magn Reson Med 2006; 56(2): 340-347.
32. Donahue KM, Burstein D, Manning WJ, Gray ML. Studies of Gd-DTPA relaxivity and proton exchange rates in tissue. Magn Reson Med 1994; 32(1): 66-76.
33. Wacker CM, Wiesmann F, Bock M, Jakob P, Sandstede JJ, Lehning A, Ertl G, Schad LR, Haase A, Bauer WR. Determination of regional blood volume and intra-extracapillary water exchange in human myocardium using Feruglose: first clinical results in patients with coronary artery disease. Magn Reson Med 2002; 47(5): 1013-1016.
34. Larsson HB, Rosenbaum S, Fritz-Hansen T. Quantification of the effect of water exchange in dynamic contrast MRI perfusion measurements in the brain and heart. Magn Reson Med 2001; 46(2): 272-281.
35. Springer C, Rooney WD, Li X. The effects of equilibrium transcytolemmal water exchange on the determination of contrast reagent concentration in vivo. Magn Reson Med 2002; 47: 422-424.
36. Rose CP, Goresky CA, Bach GG. The capillary and sarcolemmal barriers in the heart. An exploration of labeled water permeability. Circ Res 1977; 41(4): 515-533.
37. Abbott NJ, Chugani DC, Zaharchuk G, Rosen BR, Lo EH. Delivery of imaging agents into brain. Adv Drug Deliv Rev 1999; 37(1-3): 253-277.
38. 2O relaxography of the perfused rat heart. Proceedings of the 14th Annual Meeting ISMRM, Seattle, USA. 2006; 1176.
39. Neyran B, Janier MF, Casali C, Revel D, Canet Soulas EP. Mapping myocardial perfusion with an intravascular MR contrast agent: robustness of deconvolution methods at various blood flows. Magn Reson Med 2002; 48(1): 166-179.
40. Kraitchman DL, Chin BB, Heldman AW, Solaiyappan M, Bluemke DA. MRI detection of myocardial perfusion defects due to coronary artery stenosis with MS-325. J. Magn Reson Imaging 2002; 15(2): 149-158.
41. Jerosch-Herold M, Wilke N, Wang Y, Gong GR, Mansoor AM, Huang H, Gurchumelidze S, Stillman AE. Direct comparison of an intravascular and an extracellular contrast agent for quantification of myocardial perfusion. Cardiac MRI Group. Int J Card Imaging 1999; 15(6): 453-464.
42. Crystal GJ, Downey HF, Bashour FA. Small vessel and total coronary blood volume during intracoronary adenosine. Am J Physiol 1981; 241: H194-H201.
43. Caldwell JH, Martin GV, Raymond GM, Bassingthwaighte JB. Regional myocardial flow and capillary permeability-surface area products are nearly proportional. Am J Physiol 1994; 267: H654-H666.
44. Kellen MR, Bassingthwaighte JB. Transient transcapillary exchange of water driven by osmotic forces in the heart. Am J Physiol 2003; 285(3): H1317-H1331.