A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation

Oncotarget

Volumn 5, Issue 1, 2014, Pages 131-139

  Munkley, Jennifer ^a   Rajan, Prabhakar ^b,c   Lafferty, Nicholas P ^a   Dalgliesh, Caroline ^a   Jackson, Robert M ^a   Robson, Craig N ^a   Leung, Hing Y ^b,c   Elliott, David J ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Androgen; MRNA isoform; mTOR; Prostate cancer; TSC2

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; RHEB PROTEIN; TUBERIN; ISOPROTEIN; MESSENGER RNA; MTOR PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; CANCER CELL CULTURE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE S PHASE; CELL FRACTIONATION; CELL PROLIFERATION; CELL STRAIN HEK293; CELL STRAIN LNCAP; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; PROMOTER REGION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TSC2 GENE; TUMOR SUPPRESSOR GENE; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL GROWTH; GENE SILENCING; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; HEK293 CELL LINE; METABOLISM; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

CELL GROWTH PROCESSES; CELL LINE, TUMOR; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HUMANS; PROTEIN ISOFORMS; RECEPTORS, ANDROGEN; RNA, MESSENGER; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS;

EID: 84893862066     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.1405     Document Type: Article

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