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Volumn 36, Issue 3, 2014, Pages 228-240

Preconditioning and post-treatment with cobalt chloride in rat model of perinatal hypoxic-ischemic encephalopathy

Author keywords

Cobalt chloride; Hypoxia inducible factor 1 ; Hypoxic ischemic encephalopathy; Neuroprotection; Postconditioning; Preconditioning

Indexed keywords

COBALT CHLORIDE; HYPOXIA-INDUCIBLE FACTOR-1Α; HYPOXIC-ISCHEMIC ENCEPHALOPATHY; NEUROPROTECTION; POSTCONDITIONING; PRECONDITIONING;

EID: 84893857107     PISSN: 03877604     EISSN: 18727131     Source Type: Journal    
DOI: 10.1016/j.braindev.2013.04.007     Document Type: Article
Times cited : (22)

References (44)
  • 1
    • 77954177555 scopus 로고    scopus 로고
    • Preconditioning and postinsult therapies for perinatal hypoxic-ischemic injury at term
    • Sanders R.D., Manning H.J., Robertson N.J., Ma D., Edwards A.D., Hagberg H., et al. Preconditioning and postinsult therapies for perinatal hypoxic-ischemic injury at term. Anesthesiology 2010, 113:233-249.
    • (2010) Anesthesiology , vol.113 , pp. 233-249
    • Sanders, R.D.1    Manning, H.J.2    Robertson, N.J.3    Ma, D.4    Edwards, A.D.5    Hagberg, H.6
  • 2
    • 59749100272 scopus 로고    scopus 로고
    • Prodeath or prosurvival: two facets of hypoxia inducible factor-1 in perinatal brain injury
    • Chen W., Ostrowski R.P., Obenaus A., Zhang J.H. Prodeath or prosurvival: two facets of hypoxia inducible factor-1 in perinatal brain injury. Exp Neurol 2009, 216:7-15.
    • (2009) Exp Neurol , vol.216 , pp. 7-15
    • Chen, W.1    Ostrowski, R.P.2    Obenaus, A.3    Zhang, J.H.4
  • 3
    • 62549102923 scopus 로고    scopus 로고
    • Preconditioning and tolerance against cerebral ischaemia: from experimental strategies to clinical use
    • Dirnagl U., Becker K., Meisel A. Preconditioning and tolerance against cerebral ischaemia: from experimental strategies to clinical use. Lancet Neurol 2009, 8:398-412.
    • (2009) Lancet Neurol , vol.8 , pp. 398-412
    • Dirnagl, U.1    Becker, K.2    Meisel, A.3
  • 4
    • 34249688691 scopus 로고    scopus 로고
    • HIF-1alpha induced-VEGF overexpression in bone marrow stem cells protects cardiomyocytes against ischemia
    • Dai Y., Xu M., Wang Y., Pasha Z., Li T., Ashraf M. HIF-1alpha induced-VEGF overexpression in bone marrow stem cells protects cardiomyocytes against ischemia. J Mol Cell Cardiol 2007, 42:1036-1044.
    • (2007) J Mol Cell Cardiol , vol.42 , pp. 1036-1044
    • Dai, Y.1    Xu, M.2    Wang, Y.3    Pasha, Z.4    Li, T.5    Ashraf, M.6
  • 5
    • 31344431801 scopus 로고    scopus 로고
    • Understanding hypoxia-induced gene expression in early development: in vitro and in vivo analysis of hypoxia-inducible factor 1-regulated zebra fish insulin-like growth factor binding protein 1 gene expression
    • Kajimura S., Aida K., Duan C. Understanding hypoxia-induced gene expression in early development: in vitro and in vivo analysis of hypoxia-inducible factor 1-regulated zebra fish insulin-like growth factor binding protein 1 gene expression. Mol Cell Biol 2006, 26:1142-1155.
    • (2006) Mol Cell Biol , vol.26 , pp. 1142-1155
    • Kajimura, S.1    Aida, K.2    Duan, C.3
  • 6
    • 27744556130 scopus 로고    scopus 로고
    • Heme oxygenase-1-dependent and -independent regulation of angiogenic genes expression: effect of cobalt protoporphyrin and cobalt chloride on VEGF and IL-8 synthesis in human microvascular endothelial cells
    • Loboda A., Jazwa A., Wegiel B., Jozkowicz A., Dulak J. Heme oxygenase-1-dependent and -independent regulation of angiogenic genes expression: effect of cobalt protoporphyrin and cobalt chloride on VEGF and IL-8 synthesis in human microvascular endothelial cells. Cell Mol Biol 2005, 51:347-355.
    • (2005) Cell Mol Biol , vol.51 , pp. 347-355
    • Loboda, A.1    Jazwa, A.2    Wegiel, B.3    Jozkowicz, A.4    Dulak, J.5
  • 7
    • 9344262366 scopus 로고    scopus 로고
    • Cobalt chloride induces delayed cardiac preconditioning in mice through selective activation of HIF-1alpha and AP-1 and iNOS signaling
    • Xi L., Taher M., Yin C., Salloum F., Kukreja R.C. Cobalt chloride induces delayed cardiac preconditioning in mice through selective activation of HIF-1alpha and AP-1 and iNOS signaling. Am J Physiol Heart Circ Physiol 2004, 287:H2369-H2375.
    • (2004) Am J Physiol Heart Circ Physiol , vol.287
    • Xi, L.1    Taher, M.2    Yin, C.3    Salloum, F.4    Kukreja, R.C.5
  • 9
    • 0037041012 scopus 로고    scopus 로고
    • Identification and functional analysis of the rat caspase-3 gene promoter
    • Liu W., Wang G., Yakovlev A.G. Identification and functional analysis of the rat caspase-3 gene promoter. J Biol Chem 2002, 277:8273-8278.
    • (2002) J Biol Chem , vol.277 , pp. 8273-8278
    • Liu, W.1    Wang, G.2    Yakovlev, A.G.3
  • 11
    • 49349109477 scopus 로고    scopus 로고
    • HIF-1alpha inhibition ameliorates neonatal brain injury in a rat pup hypoxic-ischemic model
    • Chen W., Jadhav V., Tang J., Zhang J.H. HIF-1alpha inhibition ameliorates neonatal brain injury in a rat pup hypoxic-ischemic model. Neurobiol Dis 2008, 31:433-441.
    • (2008) Neurobiol Dis , vol.31 , pp. 433-441
    • Chen, W.1    Jadhav, V.2    Tang, J.3    Zhang, J.H.4
  • 12
    • 75149157036 scopus 로고    scopus 로고
    • Hypoxia and angiogenesis: regulation of hypoxia-inducible factors via novel binding factors
    • Chen L., Endler A., Shibasaki F. Hypoxia and angiogenesis: regulation of hypoxia-inducible factors via novel binding factors. Exp Mol Med 2009, 41:849-857.
    • (2009) Exp Mol Med , vol.41 , pp. 849-857
    • Chen, L.1    Endler, A.2    Shibasaki, F.3
  • 13
    • 33746917467 scopus 로고    scopus 로고
    • Synergistic effects of CoCl(2) and ROCK inhibition on mesenchymal stem cell differentiation into neuron-like cells
    • Pacary E., Legros H., Valable S., Duchatelle P., Lecocq M., Petit E., et al. Synergistic effects of CoCl(2) and ROCK inhibition on mesenchymal stem cell differentiation into neuron-like cells. J Cell Sci 2006, 119:2667-2678.
    • (2006) J Cell Sci , vol.119 , pp. 2667-2678
    • Pacary, E.1    Legros, H.2    Valable, S.3    Duchatelle, P.4    Lecocq, M.5    Petit, E.6
  • 14
    • 0033839757 scopus 로고    scopus 로고
    • Role of hypoxia-inducible factor-1 in hypoxia-induced ischemic tolerance in neonatal rat brain
    • Bergeron M., Gidday J.M., Yu A.Y., Semenza G.L., Ferriero D.M., Sharp F.R. Role of hypoxia-inducible factor-1 in hypoxia-induced ischemic tolerance in neonatal rat brain. Ann Neurol 2000, 48:285-296.
    • (2000) Ann Neurol , vol.48 , pp. 285-296
    • Bergeron, M.1    Gidday, J.M.2    Yu, A.Y.3    Semenza, G.L.4    Ferriero, D.M.5    Sharp, F.R.6
  • 16
    • 0019366919 scopus 로고
    • The influence of immaturity on hypoxic-ischemic brain damage in the rat
    • Rice J.E., Vannucci R.C., Brierley J.B. The influence of immaturity on hypoxic-ischemic brain damage in the rat. Ann Neurol 1981, 9:131-141.
    • (1981) Ann Neurol , vol.9 , pp. 131-141
    • Rice, J.E.1    Vannucci, R.C.2    Brierley, J.B.3
  • 17
    • 0142149237 scopus 로고    scopus 로고
    • Effect of hyperbaric oxygen on apoptosis in neonatal hypoxia-ischemia rat model
    • Calvert J.W., Zhou C., Nanda A., Zhang J.H. Effect of hyperbaric oxygen on apoptosis in neonatal hypoxia-ischemia rat model. J Appl Physiol 2003, 95:2072-2080.
    • (2003) J Appl Physiol , vol.95 , pp. 2072-2080
    • Calvert, J.W.1    Zhou, C.2    Nanda, A.3    Zhang, J.H.4
  • 18
    • 2542622162 scopus 로고    scopus 로고
    • Search strategies used by APP transgenic mice during navigation in the Morris water maze
    • Janus C. Search strategies used by APP transgenic mice during navigation in the Morris water maze. Learn Mem 2004, 11:337-346.
    • (2004) Learn Mem , vol.11 , pp. 337-346
    • Janus, C.1
  • 19
    • 70449627018 scopus 로고    scopus 로고
    • The role and regulation of hypoxia-inducible factor-1alpha expression in brain development and neonatal hypoxic-ischemic brain injury
    • Fan X., Heijnen C.J., van der Kooij M.A., Groenendaal F., van Bel F. The role and regulation of hypoxia-inducible factor-1alpha expression in brain development and neonatal hypoxic-ischemic brain injury. Brain Res Rev 2009, 62:99-108.
    • (2009) Brain Res Rev , vol.62 , pp. 99-108
    • Fan, X.1    Heijnen, C.J.2    van der Kooij, M.A.3    Groenendaal, F.4    van Bel, F.5
  • 20
    • 0030876019 scopus 로고    scopus 로고
    • Hypoxia-ischemia, but not hypoxia alone, induces the expression of heme oxygenase-1 (HSP32) in newborn rat brain
    • Bergeron M., Ferriero D.M., Vreman H.J., Stevenson D.K., Sharp F.R. Hypoxia-ischemia, but not hypoxia alone, induces the expression of heme oxygenase-1 (HSP32) in newborn rat brain. J Cereb Blood Flow Metab 1997, 17:647-658.
    • (1997) J Cereb Blood Flow Metab , vol.17 , pp. 647-658
    • Bergeron, M.1    Ferriero, D.M.2    Vreman, H.J.3    Stevenson, D.K.4    Sharp, F.R.5
  • 21
    • 33748444603 scopus 로고    scopus 로고
    • Oxygen treatment after experimental hypoxia-ischemia in neonatal rats alters the expression of HIF-1alpha and its downstream target genes
    • Calvert J.W., Cahill J., Yamaguchi-Okada M., Zhang J.H. Oxygen treatment after experimental hypoxia-ischemia in neonatal rats alters the expression of HIF-1alpha and its downstream target genes. J Appl Physiol 2006, 101:853-865.
    • (2006) J Appl Physiol , vol.101 , pp. 853-865
    • Calvert, J.W.1    Cahill, J.2    Yamaguchi-Okada, M.3    Zhang, J.H.4
  • 23
    • 0347479363 scopus 로고    scopus 로고
    • Regulation of hypoxia-inducible factor 1alpha and induction of vascular endothelial growth factor in a rat neonatal stroke model
    • Mu D., Jiang X., Sheldon R.A., Fox C.K., Hamrick S.E., Vexler Z.S., et al. Regulation of hypoxia-inducible factor 1alpha and induction of vascular endothelial growth factor in a rat neonatal stroke model. Neurobiol Dis 2003, 14:524-534.
    • (2003) Neurobiol Dis , vol.14 , pp. 524-534
    • Mu, D.1    Jiang, X.2    Sheldon, R.A.3    Fox, C.K.4    Hamrick, S.E.5    Vexler, Z.S.6
  • 24
    • 4944246547 scopus 로고    scopus 로고
    • The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis
    • Greijer A.E., van der Wall E. The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis. J Clin Pathol 2004, 57:1009-1014.
    • (2004) J Clin Pathol , vol.57 , pp. 1009-1014
    • Greijer, A.E.1    van der Wall, E.2
  • 26
    • 0035418621 scopus 로고    scopus 로고
    • Constitutive expression of hypoxia-inducible factor-1alpha renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation
    • Akakura N., Kobayashi M., Horiuchi I., Suzuki A., Wang J., Chen J., et al. Constitutive expression of hypoxia-inducible factor-1alpha renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation. Cancer Res 2001, 61:6548-6554.
    • (2001) Cancer Res , vol.61 , pp. 6548-6554
    • Akakura, N.1    Kobayashi, M.2    Horiuchi, I.3    Suzuki, A.4    Wang, J.5    Chen, J.6
  • 27
    • 34249886312 scopus 로고    scopus 로고
    • HIF-1alpha activation by a redox-sensitive pathway mediates cyanide-induced BNIP3 upregulation and mitochondrial-dependent cell death
    • Zhang L., Li L., Liu H., Prabhakaran K., Zhang X., Borowitz J.L., et al. HIF-1alpha activation by a redox-sensitive pathway mediates cyanide-induced BNIP3 upregulation and mitochondrial-dependent cell death. Free Radic Biol Med 2007, 43:117-127.
    • (2007) Free Radic Biol Med , vol.43 , pp. 117-127
    • Zhang, L.1    Li, L.2    Liu, H.3    Prabhakaran, K.4    Zhang, X.5    Borowitz, J.L.6
  • 28
    • 34447517344 scopus 로고    scopus 로고
    • Hypoxic preconditioning protects human brain endothelium from ischemic apoptosis by Akt-dependent survivin activation
    • Zhang Y., Park T.S., Gidday J.M. Hypoxic preconditioning protects human brain endothelium from ischemic apoptosis by Akt-dependent survivin activation. Am J Physiol Heart Circ Physiol 2007, 292:H2573-H2581.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Zhang, Y.1    Park, T.S.2    Gidday, J.M.3
  • 29
    • 38449121857 scopus 로고    scopus 로고
    • Hypoxia-Inducible Factor (HIF)-1 regulatory pathway and its potential for therapeutic intervention in malignancy and ischemia
    • Ziello J.E., Jovin I.S., Huang Y. Hypoxia-Inducible Factor (HIF)-1 regulatory pathway and its potential for therapeutic intervention in malignancy and ischemia. Yale J Biol Med 2007, 80:51-60.
    • (2007) Yale J Biol Med , vol.80 , pp. 51-60
    • Ziello, J.E.1    Jovin, I.S.2    Huang, Y.3
  • 30
    • 33750342490 scopus 로고    scopus 로고
    • Induced angiogenesis under cerebral ischemia by cyclooxygenase 2 and hypoxia-inducible factor naked DNA in a rat indirect-bypass model
    • Anan M., Abe T., Matsuda T., Ishii K., Kamida T., Fujiki M., et al. Induced angiogenesis under cerebral ischemia by cyclooxygenase 2 and hypoxia-inducible factor naked DNA in a rat indirect-bypass model. Neurosci Lett 2006, 409:118-123.
    • (2006) Neurosci Lett , vol.409 , pp. 118-123
    • Anan, M.1    Abe, T.2    Matsuda, T.3    Ishii, K.4    Kamida, T.5    Fujiki, M.6
  • 31
    • 67649920916 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 alpha has a key role in hypoxic preconditioning
    • Taie S., Ono J., Iwanaga Y., Tomita S., Asaga T., Chujo K., et al. Hypoxia-inducible factor-1 alpha has a key role in hypoxic preconditioning. J Clin Neurosci 2009, 16:1056-1060.
    • (2009) J Clin Neurosci , vol.16 , pp. 1056-1060
    • Taie, S.1    Ono, J.2    Iwanaga, Y.3    Tomita, S.4    Asaga, T.5    Chujo, K.6
  • 32
    • 0036211764 scopus 로고    scopus 로고
    • Normobaric hypoxia induces tolerance to focal permanent cerebral ischemia in association with an increased expression of hypoxia-inducible factor-1 and its target genes, erythropoietin and VEGF, in the adult mouse brain
    • Bernaudin M., Nedelec A.S., Divoux D., MacKenzie E.T., Petit E., Schumann-Bard P. Normobaric hypoxia induces tolerance to focal permanent cerebral ischemia in association with an increased expression of hypoxia-inducible factor-1 and its target genes, erythropoietin and VEGF, in the adult mouse brain. J Cereb Blood Flow Metab 2002, 22:393-403.
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 393-403
    • Bernaudin, M.1    Nedelec, A.S.2    Divoux, D.3    MacKenzie, E.T.4    Petit, E.5    Schumann-Bard, P.6
  • 33
    • 12844266701 scopus 로고    scopus 로고
    • Hypoxic preconditioning confers long-term reduction of brain injury and improvement of neurological ability in immature rats
    • Gustavsson M., Anderson M.F., Mallard C., Hagberg H. Hypoxic preconditioning confers long-term reduction of brain injury and improvement of neurological ability in immature rats. Pediatr Res 2005, 57:305-309.
    • (2005) Pediatr Res , vol.57 , pp. 305-309
    • Gustavsson, M.1    Anderson, M.F.2    Mallard, C.3    Hagberg, H.4
  • 34
    • 34147109855 scopus 로고    scopus 로고
    • Global gene expression in the developing rat brain after hypoxic preconditioning: involvement of apoptotic mechanisms?
    • Gustavsson M., Wilson M.A., Mallard C., Rousset C., Johnston M.V., Hagberg H. Global gene expression in the developing rat brain after hypoxic preconditioning: involvement of apoptotic mechanisms?. Pediatr Res 2007, 61:444-450.
    • (2007) Pediatr Res , vol.61 , pp. 444-450
    • Gustavsson, M.1    Wilson, M.A.2    Mallard, C.3    Rousset, C.4    Johnston, M.V.5    Hagberg, H.6
  • 35
    • 0034840276 scopus 로고    scopus 로고
    • Hypoxic preconditioning induces changes in HIF-1 target genes in neonatal rat brain
    • Jones N.M., Bergeron M. Hypoxic preconditioning induces changes in HIF-1 target genes in neonatal rat brain. J Cereb Blood Flow Metab 2001, 21:1105-1114.
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 1105-1114
    • Jones, N.M.1    Bergeron, M.2
  • 36
    • 45849134574 scopus 로고    scopus 로고
    • Long-term functional and protective actions of preconditioning with hypoxia, cobalt chloride, and desferrioxamine against hypoxic-ischemic injury in neonatal rats
    • Jones N.M., Kardashyan L., Callaway J.K., Lee E.M., Beart P.M. Long-term functional and protective actions of preconditioning with hypoxia, cobalt chloride, and desferrioxamine against hypoxic-ischemic injury in neonatal rats. Pediatr Res 2008, 63:620-624.
    • (2008) Pediatr Res , vol.63 , pp. 620-624
    • Jones, N.M.1    Kardashyan, L.2    Callaway, J.K.3    Lee, E.M.4    Beart, P.M.5
  • 37
    • 38549149924 scopus 로고    scopus 로고
    • In vivo and in vitro characterization of a novel neuroprotective strategy for stroke: ischemic postconditioning
    • Pignataro G., Meller R., Inoue K., Ordonez A.N., Ashley M.D., Xiong Z., et al. In vivo and in vitro characterization of a novel neuroprotective strategy for stroke: ischemic postconditioning. J Cereb Blood Flow Metab 2008, 28:232-241.
    • (2008) J Cereb Blood Flow Metab , vol.28 , pp. 232-241
    • Pignataro, G.1    Meller, R.2    Inoue, K.3    Ordonez, A.N.4    Ashley, M.D.5    Xiong, Z.6
  • 38
    • 57549115569 scopus 로고    scopus 로고
    • Delayed postconditioning protects against focal ischemic brain injury in rats
    • Ren C., Gao X., Niu G., Yan Z., Chen X., Zhao H. Delayed postconditioning protects against focal ischemic brain injury in rats. PLoS One 2008, 3:e3851.
    • (2008) PLoS One , vol.3
    • Ren, C.1    Gao, X.2    Niu, G.3    Yan, Z.4    Chen, X.5    Zhao, H.6
  • 39
    • 33845527528 scopus 로고    scopus 로고
    • Delayed postconditioning initiates additive mechanism necessary for survival of selectively vulnerable neurons after transient ischemia in rat brain
    • Burda J., Danielisova V., Nemethova M., Gottlieb M., Matiasova M., Domorakova I., et al. Delayed postconditioning initiates additive mechanism necessary for survival of selectively vulnerable neurons after transient ischemia in rat brain. Cell Mol Neurobiol 2006, 26:1141-1151.
    • (2006) Cell Mol Neurobiol , vol.26 , pp. 1141-1151
    • Burda, J.1    Danielisova, V.2    Nemethova, M.3    Gottlieb, M.4    Matiasova, M.5    Domorakova, I.6
  • 40
    • 70349656301 scopus 로고    scopus 로고
    • Delayed hypoxic postconditioning protects against cerebral ischemia in the mouse
    • Leconte C., Tixier E., Freret T., Toutain J., Saulnier R., Boulouard M., et al. Delayed hypoxic postconditioning protects against cerebral ischemia in the mouse. Stroke 2009, 40:3349-3355.
    • (2009) Stroke , vol.40 , pp. 3349-3355
    • Leconte, C.1    Tixier, E.2    Freret, T.3    Toutain, J.4    Saulnier, R.5    Boulouard, M.6
  • 41
    • 34250711706 scopus 로고    scopus 로고
    • Role of transcription factors in mediating post-ischemic cerebral inflammation and brain damage
    • Yi J.H., Park S.W., Kapadia R., Vemuganti R. Role of transcription factors in mediating post-ischemic cerebral inflammation and brain damage. Neurochem Int 2007, 50:1014-1027.
    • (2007) Neurochem Int , vol.50 , pp. 1014-1027
    • Yi, J.H.1    Park, S.W.2    Kapadia, R.3    Vemuganti, R.4
  • 42
    • 17644415372 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase and cyclooxygenase-2 mRNA in brain damage induced by lipopolysaccharide and intermittent hypoxia-ischemia in neonatal rats
    • Yang L., Sameshima H., Yamaguchi M., Ikenoue T. Expression of inducible nitric oxide synthase and cyclooxygenase-2 mRNA in brain damage induced by lipopolysaccharide and intermittent hypoxia-ischemia in neonatal rats. J Obstet Gynaecol Res 2005, 31:185-191.
    • (2005) J Obstet Gynaecol Res , vol.31 , pp. 185-191
    • Yang, L.1    Sameshima, H.2    Yamaguchi, M.3    Ikenoue, T.4
  • 43
    • 0034131137 scopus 로고    scopus 로고
    • Immature brain injury via peroxynitrite production induced by inducible nitric oxide synthase after hypoxia-ischemia in rats
    • Ikeno S., Nagata N., Yoshida S., Takahashi H., Kigawa J., Terakawa N. Immature brain injury via peroxynitrite production induced by inducible nitric oxide synthase after hypoxia-ischemia in rats. J Obstet Gynaecol Res 2000, 26:227-234.
    • (2000) J Obstet Gynaecol Res , vol.26 , pp. 227-234
    • Ikeno, S.1    Nagata, N.2    Yoshida, S.3    Takahashi, H.4    Kigawa, J.5    Terakawa, N.6
  • 44
    • 10644287654 scopus 로고    scopus 로고
    • Nitric oxide, hypoxia and brain inflammation
    • Mander P., Brown G.C. Nitric oxide, hypoxia and brain inflammation. Biochem Soc Trans 2004, 32:1068-1069.
    • (2004) Biochem Soc Trans , vol.32 , pp. 1068-1069
    • Mander, P.1    Brown, G.C.2


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