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Volumn 99, Issue 2, 2014, Pages 498-509

Synergistic cooperation between sunitinib and cisplatin promotes apoptotic cell death in human medullary thyroid cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA, MEDULLARY; CELL LINE, TUMOR; CELL PROLIFERATION; CISPLATIN; DRUG SYNERGISM; HUMANS; INDOLES; MICE; PROTEIN KINASE INHIBITORS; PYRROLES; THYROID NEOPLASMS;

EID: 84893789057     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2013-2574     Document Type: Article
Times cited : (21)

References (40)
  • 1
    • 77952877804 scopus 로고    scopus 로고
    • Molecular genetics and phenomics of ret mutations: Impact on prognosis of mtc
    • Frank-Raue K, Rondot S, Raue F. Molecular genetics and phenomics of RET mutations: Impact on prognosis of MTC. Mol Cell Endocrinol. 2010;322:2-7.
    • (2010) Mol Cell Endocrinol. , vol.322 , pp. 2-7
    • Frank-Raue, K.1    Rondot, S.2    Raue, F.3
  • 2
    • 77954219743 scopus 로고    scopus 로고
    • Targeted therapy of thyroid cancer
    • Sherman SI. Targeted therapy of thyroid cancer. Biochem Pharmacol. 2010;80:592-601.
    • (2010) Biochem Pharmacol. , vol.80 , pp. 592-601
    • Sherman, S.I.1
  • 3
    • 84655175698 scopus 로고    scopus 로고
    • Vandetanib in patients with locally advanced or metastatic medullary thyroid cancer: A randomized, double-blind phase iii trial
    • Wells SA Jr, Robinson BG, Gagel RF, et al. Vandetanib in patients with locally advanced or metastatic medullary thyroid cancer: a randomized, double-blind phase III trial. J Clin Oncol. 2012;30: 134-141.
    • (2012) J Clin Oncol. , vol.30 , pp. 134-141
    • Wells Jr., S.A.1    Robinson, B.G.2    Gagel, R.F.3
  • 4
    • 84863890768 scopus 로고    scopus 로고
    • Vandetanib for the treatment of symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease: Us food and drug administration drug approval summary
    • Thornton K, Kim G, Maher VE, et al. Vandetanib for the treatment of symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease: US Food and Drug Administration drug approval summary. Clin Cancer Res. 2012;18:3722-3730.
    • (2012) Clin Cancer Res. , vol.18 , pp. 3722-3730
    • Thornton, K.1    Kim, G.2    Maher, V.E.3
  • 5
    • 84873883043 scopus 로고    scopus 로고
    • Profile of cabozantinib and its potential in the treatment of advanced medullary thyroid cancer
    • Hart CD, De Boer RH. Profile of cabozantinib and its potential in the treatment of advanced medullary thyroid cancer. Onco Targets Ther. 2013;6:1-7.
    • (2013) Onco Targets Ther. , vol.6 , pp. 1-7
    • Hart, C.D.1    De Boer, R.H.2
  • 6
    • 73149115248 scopus 로고    scopus 로고
    • Targeting the ret pathway in thyroid cancer
    • Wells SA Jr, Santoro M. Targeting the RET pathway in thyroid cancer. Clin Cancer Res. 2009;15:7119-7123.
    • (2009) Clin Cancer Res. , vol.15 , pp. 7119-7123
    • Wells Jr., S.A.1    Santoro, M.2
  • 11
    • 33745939304 scopus 로고    scopus 로고
    • Apoptotic cell death induction and angiogenesis inhibition in large established medullary thyroid carcinoma xenografts by ret inhibitor rpi-1
    • Petrangolini G, Cuccuru G, Lanzi C, et al. Apoptotic cell death induction and angiogenesis inhibition in large established medullary thyroid carcinoma xenografts by Ret inhibitor RPI-1. Biochem Pharmacol. 2006;72:405-414.
    • (2006) Biochem Pharmacol. , vol.72 , pp. 405-414
    • Petrangolini, G.1    Cuccuru, G.2    Lanzi, C.3
  • 12
    • 77956114179 scopus 로고    scopus 로고
    • Combination of ret sirna and irinotecan inhibited the growth of medullary thyroid carcinoma tt cells and xenografts via apoptosis
    • Koga K, Hattori Y, Komori M, et al. Combination of RET siRNA and irinotecan inhibited the growth of medullary thyroid carcinoma TT cells and xenografts via apoptosis. Cancer Sci. 2010;101:941-947.
    • (2010) Cancer Sci. , vol.101 , pp. 941-947
    • Koga, K.1    Hattori, Y.2    Komori, M.3
  • 13
    • 79953783589 scopus 로고    scopus 로고
    • Evaluation of systemic targeting of ret oncogene-basedmtcwith tumor-selective peptide-Tagged ad vectors in clinical mouse models
    • Schmidt A, Eipel C, Fürst K, Sommer N, Pahnke J, Pützer BM. Evaluation of systemic targeting of RET oncogene-basedMTCwith tumor-selective peptide-Tagged Ad vectors in clinical mouse models. Gene Ther. 2011;18:418-423.
    • (2011) Gene Ther. , vol.18 , pp. 418-423
    • Schmidt, A.1    Eipel, C.2    Fürst, K.3    Sommer, N.4    Pahnke, J.5    Pützer, B.M.6
  • 14
    • 1442295841 scopus 로고    scopus 로고
    • Apoptosis and dependence receptors: A molecular basis for cellular addiction
    • Bredesen DE, Mehlen P, Rabizadeh S. Apoptosis and dependence receptors: a molecular basis for cellular addiction. Physiol Rev. 2004;84:411-430.
    • (2004) Physiol Rev. , vol.84 , pp. 411-430
    • Bredesen, D.E.1    Mehlen, P.2    Rabizadeh, S.3
  • 15
    • 33746961739 scopus 로고    scopus 로고
    • Mechanisms of disease: Oncogene addiction-A rationale for molecular targeting in cancer therapy
    • Weinstein IB, Joe AK. Mechanisms of disease: oncogene addiction-A rationale for molecular targeting in cancer therapy. Nat Clin Pract Oncol. 2006;3:448-457.
    • (2006) Nat Clin Pract Oncol. , vol.3 , pp. 448-457
    • Weinstein, I.B.1    Joe, A.K.2
  • 16
    • 37249003928 scopus 로고    scopus 로고
    • Oncogene addiction: Setting the stage for molecularly targeted cancer therapy
    • Sharma SV, Settleman J. Oncogene addiction: setting the stage for molecularly targeted cancer therapy. Genes Dev. 2007;21:3214-3231.
    • (2007) Genes Dev. , vol.21 , pp. 3214-3231
    • Sharma, S.V.1    Settleman, J.2
  • 17
    • 4344566311 scopus 로고    scopus 로고
    • Role of men2a-derived ret in maintenance and proliferation of medullary thyroid carcinoma
    • Drosten M, Hilken G, Böckmann M, et al. Role of MEN2A-derived RET in maintenance and proliferation of medullary thyroid carcinoma. J Natl Cancer Inst. 2004;96:1231-1239.
    • (2004) J Natl Cancer Inst. , vol.96 , pp. 1231-1239
    • Drosten, M.1    Hilken, G.2    Böckmann, M.3
  • 18
    • 80051783194 scopus 로고    scopus 로고
    • Interplay between ret and fap-1 regulates cd95-mediated apoptosis in medullary thyroid cancer cells
    • Nicolini V, Cassinelli G, Cuccuru G, et al. Interplay between Ret and Fap-1 regulates CD95-mediated apoptosis in medullary thyroid cancer cells. Biochem Pharmacol. 2011;82:778-788.
    • (2011) Biochem Pharmacol. , vol.82 , pp. 778-788
    • Nicolini, V.1    Cassinelli, G.2    Cuccuru, G.3
  • 19
    • 78049462514 scopus 로고    scopus 로고
    • Phase ii study of daily sunitinib in fdg-pet-positive, iodine-refractory differentiated thyroid cancer and metastatic medullary carcinoma of the thyroid with functional imaging correlation
    • Carr LL, Mankoff DA, Goulart BH, et al. Phase II study of daily sunitinib in FDG-PET-positive, iodine-refractory differentiated thyroid cancer and metastatic medullary carcinoma of the thyroid with functional imaging correlation. Clin Cancer Res. 2010;16:5260-5268.
    • (2010) Clin Cancer Res. , vol.16 , pp. 5260-5268
    • Carr, L.L.1    Mankoff, D.A.2    Goulart, B.H.3
  • 21
    • 0038494539 scopus 로고    scopus 로고
    • Loss of druginduced activation of the cd95 apoptotic pathway in a cisplatinresistant testicular germ cell tumor cell line
    • Spierings DC, de Vries EG, Vellenga E, de Jong S. Loss of druginduced activation of the CD95 apoptotic pathway in a cisplatinresistant testicular germ cell tumor cell line. Cell Death Differ. 2003; 10:808-822.
    • (2003) Cell Death Differ. , vol.10 , pp. 808-822
    • Spierings, D.C.1    De Vries, E.G.2    Vellenga, E.3    De Jong, S.4
  • 22
    • 2442693091 scopus 로고    scopus 로고
    • Cisplatin-induced cd95 redistribution into membrane lipid rafts of ht29 human colon cancer cells
    • Lacour S, Hammann A, Grazide S, et al. Cisplatin-induced CD95 redistribution into membrane lipid rafts of HT29 human colon cancer cells. Cancer Res. 2004;64:3593-3598.
    • (2004) Cancer Res. , vol.64 , pp. 3593-3598
    • Lacour, S.1    Hammann, A.2    Grazide, S.3
  • 24
    • 12244301581 scopus 로고    scopus 로고
    • In vivo antitumor activity of su11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship
    • Mendel DB, Laird AD, Xin X, et al. In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship. Clin Cancer Res. 2003;9:327-337.
    • (2003) Clin Cancer Res. , vol.9 , pp. 327-337
    • Mendel, D.B.1    Laird, A.D.2    Xin, X.3
  • 25
    • 0033883775 scopus 로고    scopus 로고
    • Thyroid carcinoma cells are resistant to fas-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand
    • Mitsiades N, Poulaki V, Tseleni-Balafouta S, Koutras DA, Stamenkovic I. Thyroid carcinoma cells are resistant to FAS-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand. Cancer Res. 2000;60:4122-4129.
    • (2000) Cancer Res. , vol.60 , pp. 4122-4129
    • Mitsiades, N.1    Poulaki, V.2    Tseleni-Balafouta, S.3    Koutras, D.A.4    Stamenkovic, I.5
  • 26
    • 58149086851 scopus 로고    scopus 로고
    • Synthesis, modeling, and ret protein kinase inhibitory activity of 3-And 4-substituted -carbolin-1-ones
    • Cincinelli R, Cassinelli G, Dallavalle S, et al. Synthesis, modeling, and RET protein kinase inhibitory activity of 3-And 4-substituted -carbolin-1-ones. J Med Chem. 2008;51:7777-7787.
    • (2008) J Med Chem. , vol.51 , pp. 7777-7787
    • Cincinelli, R.1    Cassinelli, G.2    Dallavalle, S.3
  • 27
    • 33947504730 scopus 로고    scopus 로고
    • Sunitinib: From rational design to clinical efficacy
    • Chow LQ, Eckhardt SG. Sunitinib: from rational design to clinical efficacy. J Clin Oncol. 2007;25:884-896.
    • (2007) J Clin Oncol. , vol.25 , pp. 884-896
    • Chow, L.Q.1    Eckhardt, S.G.2
  • 28
    • 79960094269 scopus 로고    scopus 로고
    • Mammalian target of rapamycin pathway activation is associated to ret mutation status in medullary thyroid carcinoma
    • Rapa I, Saggiorato E, Giachino D, et al. Mammalian target of rapamycin pathway activation is associated to RET mutation status in medullary thyroid carcinoma. J Clin Endocrinol Metab. 2011;96: 2146-2153.
    • (2011) J Clin Endocrinol Metab. , vol.96 , pp. 2146-2153
    • Rapa, I.1    Saggiorato, E.2    Giachino, D.3
  • 29
    • 76549129820 scopus 로고    scopus 로고
    • Drug combination studies and their synergy quantification using the chou-Talalay method
    • Chou TC. Drug combination studies and their synergy quantification using the Chou-Talalay method. Cancer Res. 2010;70:440-446.
    • (2010) Cancer Res. , vol.70 , pp. 440-446
    • Chou, T.C.1
  • 30
    • 84857366779 scopus 로고    scopus 로고
    • The autophagic paradox in cancer therapy
    • Wu WK, Coffelt SB, Cho CH, et al. The autophagic paradox in cancer therapy. Oncogene. 2012;31:939-953.
    • (2012) Oncogene. , vol.31 , pp. 939-953
    • Wu, W.K.1    Coffelt, S.B.2    Cho, C.H.3
  • 31
    • 84862295360 scopus 로고    scopus 로고
    • Guidelines for the use and interpretation of assays for monitoring autophagy
    • Klionsky DJ, Abdalla FC, Abeliovich H, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012;8:445-544.
    • (2012) Autophagy. , vol.8 , pp. 445-544
    • Klionsky, D.J.1    Abdalla, F.C.2    Abeliovich, H.3
  • 33
    • 82555189379 scopus 로고    scopus 로고
    • Lysosomal sequestration of sunitinib: A novel mechanism of drug resistance
    • Gotink KJ, Broxterman HJ, Labots M, et al. Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance. Clin Cancer Res. 2011;17:7337-7346.
    • (2011) Clin Cancer Res. , vol.17 , pp. 7337-7346
    • Gotink, K.J.1    Broxterman, H.J.2    Labots, M.3
  • 34
    • 69249140641 scopus 로고    scopus 로고
    • Lysosomes as "suicide bags" in cell death: Myth or reality?
    • Turk B, Turk V. Lysosomes as "suicide bags" in cell death: myth or reality? J Biol Chem. 2009;284:21783-21787.
    • (2009) J Biol Chem. , vol.284 , pp. 21783-21787
    • Turk, B.1    Turk, V.2
  • 35
    • 84878347807 scopus 로고    scopus 로고
    • Acquired differential regulation of caspase-8 in cisplatin-resistant non-small-cell lung cancer
    • Paul I, Chacko AD, Stasik I, et al. Acquired differential regulation of caspase-8 in cisplatin-resistant non-small-cell lung cancer. Cell Death Dis. 2012;3:e449.
    • (2012) Cell Death Dis. , vol.3
    • Paul, I.1    Chacko, A.D.2    Stasik, I.3
  • 36
    • 79953328085 scopus 로고    scopus 로고
    • Identification of soluble candidate biomarkers of therapeutic response to sunitinib in medullary thyroid carcinoma in preclinical models
    • Broutin S, Ameur N, Lacroix L, et al. Identification of soluble candidate biomarkers of therapeutic response to sunitinib in medullary thyroid carcinoma in preclinical models. Clin Cancer Res. 2011;17: 2044-2054.
    • (2011) Clin Cancer Res. , vol.17 , pp. 2044-2054
    • Broutin, S.1    Ameur, N.2    Lacroix, L.3
  • 37
    • 84869460494 scopus 로고    scopus 로고
    • Autophagic activation potentiates the antiproliferative effects of tyrosine kinase inhibitors in medullary thyroid cancer
    • Lin CI, Whang EE, Lorch JH, Ruan DT. Autophagic activation potentiates the antiproliferative effects of tyrosine kinase inhibitors in medullary thyroid cancer. Surgery. 2012;152:1142-1149.
    • (2012) Surgery. , vol.152 , pp. 1142-1149
    • Lin, C.I.1    Whang, E.E.2    Lorch, J.H.3    Ruan, D.T.4
  • 38
    • 34548188741 scopus 로고    scopus 로고
    • Self-eating and self-killing: Crosstalk between autophagy and apoptosis
    • Maiuri MC, Zalckvar E, Kimchi A, Kroemer G. Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol. 2007;8:741-752.
    • (2007) Nat Rev Mol Cell Biol. , vol.8 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 39
    • 84861671713 scopus 로고    scopus 로고
    • Lysosomal pathways to cell death and their therapeutic applications
    • Česen MH, Pegan K, Spes A, Turk B. Lysosomal pathways to cell death and their therapeutic applications. Exp Cell Res. 2012;318: 1245-1251.
    • (2012) Exp Cell Res. , vol.318 , pp. 1245-1251
    • Česen, M.H.1    Pegan, K.2    Spes, A.3    Turk, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.