메뉴 건너뛰기




Volumn 15, Issue 11, 2013, Pages

Mechanistic insights from animal models of psoriasis and psoriatic arthritis

Author keywords

Animal models; Dactylitis; Enthesitis; Geneticmutations; IL 17; IL 22; IL 23; Psoriasis; Psoriatic arthritis; Rheumatoid arthritis; Spondyloarthritis

Indexed keywords

ANIMAL; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, PSORIATIC; ARTHRITIS, RHEUMATOID; DISEASE MODEL; GENETICS; MOUSE; MUTATION; PSORIASIS; SPONDYLARTHRITIS; EXPERIMENTAL ARTHRITIS; PSORIATIC ARTHRITIS; REVIEW; RHEUMATOID ARTHRITIS;

EID: 84893778801     PISSN: 15233774     EISSN: 15346307     Source Type: Journal    
DOI: 10.1007/s11926-013-0377-4     Document Type: Article
Times cited : (18)

References (39)
  • 1
    • 58149336900 scopus 로고    scopus 로고
    • The prevalence of previously diagnosed and undiagnosed psoriasis in US adults: Results from NHANES 2003-2004
    • Kurd SK, Gelfand JM. The prevalence of previously diagnosed and undiagnosed psoriasis in US adults: results from NHANES 2003-2004. J Am Acad Dermatol. 2009;60(2):218-24
    • (2009) J Am Acad Dermatol , vol.60 , Issue.2 , pp. 218-224
    • Kurd, S.K.1    Gelfand, J.M.2
  • 3
    • 70349775684 scopus 로고    scopus 로고
    • The prevalence of psoriatic arthritis in people with psoriasis
    • Ibrahim G, Waxman R, Helliwell PS. The prevalence of psoriatic arthritis in people with psoriasis. Arthritis Rheum. 2009;61(10): 1373-8
    • (2009) Arthritis Rheum , vol.61 , Issue.10 , pp. 1373-1378
    • Ibrahim, G.1    Waxman, R.2    Helliwell, P.S.3
  • 5
    • 0002808542 scopus 로고
    • Ara nomenclature and classification of arthritis and rheumatism (tentative)
    • Blumberg BS et al. Ara nomenclature and classification of arthritis and rheumatism (tentative). Arthritis Rheum. 1964;7:93-7
    • (1964) Arthritis Rheum , vol.7 , pp. 93-97
    • Blumberg, B.S.1
  • 6
    • 84864856809 scopus 로고    scopus 로고
    • What have genome-wide studies told us about psoriatic arthritis?
    • Bluett J, Barton A. What have genome-wide studies told us about psoriatic arthritis? Curr Rheumatol Rep. 2012;14(4):364-8
    • (2012) Curr Rheumatol Rep , vol.14 , Issue.4 , pp. 364-368
    • Bluett, J.1    Barton, A.2
  • 7
    • 73349120009 scopus 로고    scopus 로고
    • A strong heritability of psoriatic arthritis over four generations-The reykjavik psoriatic arthritis study
    • Karason A, Love TJ, Gudbjornsson B. A strong heritability of psoriatic arthritis over four generations-the Reykjavik Psoriatic Arthritis Study. Rheumatology (Oxford). 2009;48(11):1424-8
    • (2009) Rheumatology (Oxford) , vol.48 , Issue.11 , pp. 1424-1428
    • Karason, A.1    Love, T.J.2    Gudbjornsson, B.3
  • 8
    • 33750388473 scopus 로고    scopus 로고
    • Animal models of psoriasis and psoriatic arthritis: An update
    • DOI 10.1007/s11926-006-0063-x
    • Conrad C, Nestle FO. Animal models of psoriasis and psoriatic arthritis: an update. Curr Rheumatol Rep. 2006;8(5):342-7 (Pubitemid 44638826)
    • (2006) Current Rheumatology Reports , vol.8 , Issue.5 , pp. 342-347
    • Conrad, C.1    Nestle, F.O.2
  • 9
    • 0018830639 scopus 로고
    • Immunisation against heterologous type II collagen induces arthritis in mice
    • Courtenay JS et al. Immunisation against heterologous type II collagen induces arthritis in mice. Nature. 1980;283(5748):666-8 (Pubitemid 10099994)
    • (1980) Nature , vol.283 , Issue.5748 , pp. 666-668
    • Courtenay, J.S.1    Dallman, M.J.2    Dayan, A.D.3
  • 11
    • 0029320267 scopus 로고
    • High prevalence of colorectal cancer in HLA-B27 transgenic F344 rats with chronic inflammatory bowel disease
    • Hammer RE et al. High prevalence of colorectal cancer in HLA-B27 transgenic F344 rats with chronic inflammatory bowel disease. JInvestig Med. 1995;43(3):262-8
    • (1995) JInvestig Med , vol.43 , Issue.3 , pp. 262-268
    • Hammer, R.E.1
  • 12
    • 0029083655 scopus 로고
    • Spontaneous inflammatory arthritis in HLA-B27 transgenic mice lacking beta 2-microglobulin: A model of human spondyloarthropathies
    • Khare SD, Luthra HS, David CS. Spontaneous inflammatory arthritis in HLA-B27 transgenic mice lacking beta 2-microglobulin: a model of human spondyloarthropathies. J Exp Med. 1995;182(4):1153-8
    • (1995) J Exp Med , vol.182 , Issue.4 , pp. 1153-1158
    • Khare, S.D.1    Luthra, H.S.2    David, C.S.3
  • 13
    • 78049350350 scopus 로고    scopus 로고
    • Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis
    • This genome-wide study revealed an association of Ps and PsA with TRAF3IP2. This may prompt further investigation to find biomarkers that enable prognostication in patients with Ps who may be at risk of PsA
    • Huffmeier U et al. Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis. Nat Genet. 2010;42(11):996-9. This genome-wide study revealed an association of Ps and PsA with TRAF3IP2. This may prompt further investigation to find biomarkers that enable prognostication in patients with Ps who may be at risk of PsA
    • (2010) Nat Genet , vol.42 , Issue.11 , pp. 996-999
    • Huffmeier, U.1
  • 14
    • 84858664948 scopus 로고    scopus 로고
    • Beta-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice
    • This study effectively revealed that the microbial environment towhich animals and possibly humans are exposed can have dramatic effect on inflammation and development of a disease phenotype- notably SpA
    • Ruutu M et al. beta-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice. Arthritis Rheum. 2012;64(7):2211-3 22. This study effectively revealed that the microbial environment towhich animals and possibly humans are exposed can have dramatic effect on inflammation and development of a disease phenotype- notably SpA
    • (2012) Arthritis Rheum , vol.64 , Issue.7 , pp. 2211-2222
    • Ruutu, M.1
  • 15
    • 84871214659 scopus 로고    scopus 로고
    • The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90
    • This study revealed that a loss of function mutation in Act1 and chaperone protein hsp90, which results in absence of IL-17, was still associated with the development of inflammatory skin lesions that were driven by IL-22, implicating this cytokine as a potential therapeutic target
    • Wang C et al. The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90. Nat Immunol. 2013;14(1):72-81. This study revealed that a loss of function mutation in Act1 and chaperone protein hsp90, which results in absence of IL-17, was still associated with the development of inflammatory skin lesions that were driven by IL-22, implicating this cytokine as a potential therapeutic target
    • (2013) Nat Immunol , vol.14 , Issue.1 , pp. 72-81
    • Wang, C.1
  • 17
    • 79960492398 scopus 로고    scopus 로고
    • IL-23 is critical for induction of arthritis, osteoclast formation, and maintenance of bone mass
    • Introduction of minicircle DNA, a novel technique, for study of spondyloarthritis in animals. Affirms the role of IL-23 in the initiation and perpetuation of disease
    • Adamopoulos IE et al. IL-23 is critical for induction of arthritis, osteoclast formation, and maintenance of bone mass. J Immunol. 2011;187(2):951-9. Introduction of minicircle DNA, a novel technique, for study of spondyloarthritis in animals. Affirms the role of IL-23 in the initiation and perpetuation of disease
    • (2011) J Immunol , vol.187 , Issue.2 , pp. 951-959
    • Adamopoulos, I.E.1
  • 19
    • 3042845742 scopus 로고    scopus 로고
    • Suprabasal expression of human amphiregulin in the epidermis of transgenic mice induces a severe, early-onset, psoriasis-like skin pathology: Expression of amphiregulin in the basal epidermis is also associated with synovitis
    • DOI 10.1111/j.0906-6705.2004.00183.x
    • Cook PWet al. Suprabasal expression of human amphiregulin in the epidermis of transgenic mice induces a severe, early-onset, psoriasislikeskin pathology: expression of amphiregulin in the basal epidermisis also associated with synovitis. Exp Dermatol. 2004;13(6):347-56 (Pubitemid 38868207)
    • (2004) Experimental Dermatology , vol.13 , Issue.6 , pp. 347-356
    • Cook, P.W.1    Brown, J.R.2    Cornell, K.A.3    Pittelkow, M.R.4
  • 20
    • 78049347495 scopus 로고    scopus 로고
    • A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
    • Genetic Analysis of
    • Genetic Analysis of Psoriasis, C et al. A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet. 2010;42(11):985-90
    • (2010) Nat Genet , vol.42 , Issue.11 , pp. 985-990
    • Psoriasis, C.1
  • 21
    • 85013702372 scopus 로고    scopus 로고
    • Psoriatic and reactive arthritis: A companion to rheumatology
    • 1st ed
    • Ritchlin CT, FitzGerald O. Psoriatic and reactive arthritis: a companion to rheumatology. 1st ed. Philadelphia:Mosby Elsevier; 2007. p. 16. 236 p
    • (2007) Mosby Philadelphia:Elsevier
    • Ritchlin, C.T.1    Fitzgerald, O.2
  • 22
    • 33846955735 scopus 로고    scopus 로고
    • Why are some species more commonly afflicted by arthritis than others? A comparative study of spondyloarthropathy in primates and carnivores
    • Nunn CL, Rothschild B, Gittleman JL. Why are some species more commonly afflicted by arthritis than others? A comparative study of spondyloarthropathy in primates and carnivores. J Evol Biol.2007;20(2):460-70
    • (2007) J Evol Biol , vol.20 , Issue.2 , pp. 460-470
    • Nunn, C.L.1    Rothschild, B.2    Gittleman, J.L.3
  • 23
    • 78649857725 scopus 로고    scopus 로고
    • Psoriasis: What we have learned from mouse models
    • Wagner EF et al. Psoriasis: what we have learned from mouse models. Nat Rev Rheumatol. 2010;6(12):704-14
    • (2010) Nat Rev Rheumatol , vol.6 , Issue.12 , pp. 704-714
    • Wagner, E.F.1
  • 24
    • 84879502194 scopus 로고    scopus 로고
    • Imaging in psoriatic arthritis
    • Anandarajah A. Imaging in psoriatic arthritis. Clin Rev Allergy Immunol. 2013;44(2):157-65
    • (2013) Clin Rev Allergy Immunol , vol.44 , Issue.2 , pp. 157-165
    • Anandarajah, A.1
  • 26
    • 79959808736 scopus 로고    scopus 로고
    • Animal models for arthritis: Innovative tools for prevention and treatment
    • Kollias G et al. Animal models for arthritis: innovative tools for prevention and treatment. Ann Rheum Dis. 2011;70(8):1357-62
    • (2011) Ann Rheum Dis , vol.70 , Issue.8 , pp. 1357-1362
    • Kollias, G.1
  • 28
    • 0042232230 scopus 로고    scopus 로고
    • The TNF-α transgenic mouse model of inflammatory arthritis
    • DOI 10.1007/s00281-003-0125-3
    • Li P, Schwarz EM. The TNF-alpha transgenic mouse model of inflammatory arthritis. Springer Semin Immunopathol. 2003;25(1):19-33 (Pubitemid 37000036)
    • (2003) Springer Seminars in Immunopathology , vol.25 , Issue.1 , pp. 19-33
    • Li, P.1    Schwarz, E.M.2
  • 30
    • 59149106117 scopus 로고    scopus 로고
    • Genome-wide scan reveals association of psoriasis with IL-23 and NF- kappaB pathways
    • Nair RP et al.Genome-wide scan reveals association of psoriasis with IL-23 and NF- kappaB pathways. Nat Genet. 2009;41(2):199-204
    • (2009) Nat Genet , vol.41 , Issue.2 , pp. 199-204
    • Nair, R.P.1
  • 31
    • 73249153202 scopus 로고    scopus 로고
    • From HLA-B27 to spondyloarthritis: A journey through the ER
    • Colbert RA et al. From HLA-B27 to spondyloarthritis: a journey through the ER. Immunol Rev. 2010;233(1):181-202
    • (2010) Immunol Rev , vol.233 , Issue.1 , pp. 181-202
    • Colbert, R.A.1
  • 32
    • 84863697312 scopus 로고    scopus 로고
    • IL-23 induces spondyloarthropathy by acting on ROR-gammat+ CD3+CD4-CD8- entheseal resident T cells
    • This study also used the minicircle DNA technique and effectively revealed IL-23-induced inflammation is related to bone erosion whereas IL-22 ma have a role in new bone formation
    • Sherlock JP et al. IL-23 induces spondyloarthropathy by acting on ROR-gammat+ CD3+CD4-CD8- entheseal resident T cells. NatMed. 2012;18(7):1069-76. This study also used the minicircle DNA technique and effectively revealed IL-23-induced inflammation is related to bone erosion whereas IL-22 ma have a role in new bone formation
    • (2012) NatMed , vol.18 , Issue.7 , pp. 1069-7076
    • Sherlock, J.P.1
  • 33
    • 84863669568 scopus 로고    scopus 로고
    • Primed for inflammation: Enthesis-resident T cells
    • Lories RJ,McInnes IB. Primed for inflammation: enthesis-resident T cells. Nat Med. 2012;18(7):1018-9
    • (2012) Nat Med , vol.18 , Issue.7 , pp. 1018-1019
    • Lories, R.J.1    McInnes, I.B.2
  • 34
    • 78049343768 scopus 로고    scopus 로고
    • Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2
    • Ellinghaus E et al. Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2. Nat Genet. 2010;42(11):991-5
    • (2010) Nat Genet , vol.42 , Issue.11 , pp. 991-995
    • Ellinghaus, E.1
  • 35
    • 0036746118 scopus 로고    scopus 로고
    • Mice lacking endogenous major histocompatibility complex class 2 develop arthritis resembling psoriatic arthritis at an advanced age
    • Bardos T et al. Mice lacking endogenous major histocompatibility complex class II develop arthritis resembling psoriatic arthritis at an advanced age. Arthritis Rheum. 2002;46(9):2465-75
    • (2002) Arthritis Rheum , vol.46 , Issue.9 , pp. 2465-2475
    • Bardos, T.1
  • 36
    • 1942532044 scopus 로고    scopus 로고
    • Ankylosing enthesitis, dactylitis, and onychoperiostitis in male DBA/1 mice: A model of psoriatic arthritis
    • DOI 10.1136/ard.2003.013599
    • Lories RJ et al. Ankylosing enthesitis, dactylitis, and onychoperiostitis in male DBA/1 mice: a model of psoriatic arthritis. Ann Rheum Dis. 2004;63(5):595-8 (Pubitemid 38530208)
    • (2004) Annals of the Rheumatic Diseases , vol.63 , Issue.5 , pp. 595-598
    • Lories, R.J.U.1    Matthys, P.2    De Vlam, K.3    Derese, I.4    Luyten, F.P.5
  • 37
    • 84857990743 scopus 로고    scopus 로고
    • Inhibition of inflammation but not ankylosis by glucocorticoids in mice: Further evidence for the entheseal stress hypothesis
    • Model that provides an explanation for the uncoupling of bone homeostasis seen in spondyloarthritides as evidenced by the inability of glucocorticoids to prevent new bone formation after abrogating inflammatory response. Lends redence to the "entheseal stress " hypothesis
    • Braem K et al. Inhibition of inflammation but not ankylosis by glucocorticoids in mice: further evidence for the entheseal stress hypothesis. Arthritis Res Ther. 2012;14(2):R59. Model that provides an explanation for the uncoupling of bone homeostasis seen in spondyloarthritides as evidenced by the inability of glucocorticoids to prevent new bone formation after abrogating inflammatory response. Lends redence to the "entheseal stress " hypothesis
    • (2012) Arthritis Res Ther , vol.14 , Issue.2
    • Braem, K.1
  • 38
    • 84872106992 scopus 로고    scopus 로고
    • Spontaneous arthritis and ankylosis in male DBA/1 mice: Further evidence for a role of behavioral factors in stress-induced arthritis
    • Braem K, Carter S, Lories RJ. Spontaneous arthritis and ankylosis in male DBA/1 mice: further evidence for a role of behavioral factors in " stress-induced arthritis ". Biol Proced Online. 2012;14(1):10
    • (2012) Biol Proced Online , vol.14 , Issue.1 , pp. 10
    • Braem, K.1    Carter, S.2    Lories, R.J.3
  • 39
    • 84883134297 scopus 로고    scopus 로고
    • Efficacy and safety of ustekinumab in patients with active psoriatic arthritis: 1 year results of the phase 3, multicentre, double-blind, placebo-controlled PSUMMIT 1 trial
    • McInnes IB, et al. Efficacy and safety of ustekinumab in patients with active psoriatic arthritis: 1 year results of the phase 3, multicentre, double-blind, placebo-controlled PSUMMIT 1 trial. Lancet. 2013
    • (2013) Lancet
    • McInnes, I.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.