Stem cell profiling in head and neck cancer reveals an Oct-4 expressing subpopulation with properties of chemoresistance

Oral Oncology

Volumn 50, Issue 3, 2014, Pages 155-162

  Reers, Stefan ^a   Pfannerstill, Ann Christin ^a   Maushagen, Regina ^a   Pries, Ralph ^a   Wollenberg, Barbara ^a  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

Author keywords

Cancer stem cells; CD44; GATA4; Goosecoid; Head and neck cancer; HNF 3 FoxA2; HNSCC; Oct 4; Oct 4A; Otx2; PDX 1 IPF1; Sox17; Stem cell profiling

Indexed keywords

ANTINEOPLASTIC AGENT; OCTAMER TRANSCRIPTION FACTOR 4;

APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CANCER RESISTANCE; CANCER STEM CELL; CELL PROLIFERATION; CELL SUBPOPULATION; CONTROLLED STUDY; FLOW CYTOMETRY; GROWTH INHIBITION; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MICROARRAY; SOLID TUMOR; STEM CELL;

CANCER STEM CELLS; CD44; GATA4; GOOSECOID; HEAD AND NECK CANCER; HNF-3SS/FOXA2; HNSCC; OCT-4; OCT-4A; OTX2; PDX-1/IPF1; SOX17; STEM CELL PROFILING;

CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; COLORIMETRY; FLOW CYTOMETRY; HEAD AND NECK NEOPLASMS; HUMANS; NEOPLASTIC STEM CELLS; OCTAMER TRANSCRIPTION FACTOR-3; PROTEIN ARRAY ANALYSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 84893749400     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2013.12.006     Document Type: Article

References (49)

1. D. Luce et al. Alcohol and tobacco consumption in cancer of the mouth, pharynx, and larynx: a study of 316 female patients Laryngoscope 98 3 1988 313 316
2. S.P. Leong et al. Clinical patterns of metastasis Cancer Metastasis Rev 25 2 2006 221 232
3. W.G. Douglas et al. Development of head and neck squamous cell carcinoma is associated with altered cytokine responsiveness Mol Cancer Res 2 10 2004 585 593
4. R. Pries et al. Secretion of tumor-promoting and immune suppressive cytokines by cell lines of head and neck squamous cell carcinoma In Vivo 20 1 2006 45 48
5. S. Reers et al. Cytokine changes in response to radio-/chemotherapeutic treatment in head and neck cancer Anticancer Res 33 6 2013 2481 2489
6. J.E. Visvader, and G.J. Lindeman Cancer stem cells in solid tumours: accumulating evidence and unresolved questions Nat Rev Cancer 8 10 2008 755 768
7. K. Greenow, and A.R. Clarke Controlling the stem cell compartment and regeneration in vivo: the role of pluripotency pathways Physiol Rev 92 1 2012 75 99
8. C. Chen et al. Evidence for epithelial-mesenchymal transition in cancer stem cells of head and neck squamous cell carcinoma PLoS One 6 1 2011 e16466
9. D. Bonnet, and J.E. Dick Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell Nat Med 3 7 1997 730 737
10. T. Lapidot et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice Nature 367 6464 1994 645 648
11. T. Schatton, N.Y. Frank, and M.H. Frank Identification and targeting of cancer stem cells Bioessays 31 10 2009 1038 1049
12. M. Wang et al. Isolation and characterization of tumorigenic extrahepatic cholangiocarcinoma cells with stem cell-like properties Int J Cancer 128 1 2011 72 81
13. S.K. Singh et al. Identification of a cancer stem cell in human brain tumors Cancer Res 63 18 2003 5821 5828
14. M. Al-Hajj et al. Prospective identification of tumorigenic breast cancer cells Proc Natl Acad Sci USA 100 7 2003 3983 3988
15. L. Ricci-Vitiani et al. Colon cancer stem cells Gut 57 4 2008 538 548
16. D. Huang et al. Isolation and identification of cancer stem-like cells in esophageal carcinoma cell lines Stem Cells Dev 18 3 2009 465 473
17. A. Suetsugu et al. Characterization of CD133+ hepatocellular carcinoma cells as cancer stem/progenitor cells Biochem Biophys Res Commun 351 4 2006 820 824
18. A. Eramo et al. Identification and expansion of the tumorigenic lung cancer stem cell population Cell Death Differ 15 3 2008 504 514
19. C. Li et al. Identification of pancreatic cancer stem cells Cancer Res 67 3 2007 1030 1037
20. S. Takaishi et al. Identification of gastric cancer stem cells using the cell surface marker CD44 Stem Cells 27 5 2009 1006 1020
21. L. Patrawala et al. Hierarchical organization of prostate cancer cells in xenograft tumors: the CD44+alpha2beta1+ cell population is enriched in tumor-initiating cells Cancer Res 67 14 2007 6796 6805
22. M.E. Prince et al. Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma Proc Natl Acad Sci USA 104 3 2007 973 978
23. A. Okamoto et al. Expansion and characterization of cancer stem-like cells in squamous cell carcinoma of the head and neck Oral Oncol 45 7 2009 633 639
24. T. Kawano et al. Expression of E-cadherin, and CD44s and CD44v6 and its association with prognosis in head and neck cancer Auris Nasus Larynx 31 1 2004 35 41
25. R. Pries et al. Potential stem cell marker CD44 is constitutively expressed in permanent cell lines of head and neck cancer In Vivo 22 1 2008 89 92
26. K. Okamoto et al. A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells Cell 60 3 1990 461 472
27. M.H. Rosner et al. A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo Nature 345 6277 1990 686 692
28. J.B. Kim et al. Oct4-induced pluripotency in adult neural stem cells Cell 136 3 2009 411 419
29. J. Yu et al. Induced pluripotent stem cell lines derived from human somatic cells Science 318 5858 2007 1917 1920
30. S. Gidekel et al. Oct-3/4 is a dose-dependent oncogenic fate determinant Cancer Cell 4 5 2003 361 370
31. L. Hu, C. McArthur, and R.B. Jaffe Ovarian cancer stem-like side-population cells are tumourigenic and chemoresistant Br J Cancer 102 8 2010 1276 1283
32. G. Cauffman et al. POU5F1 isoforms show different expression patterns in human embryonic stem cells and preimplantation embryos Stem Cells 24 12 2006 2685 2691
33. J. Lee et al. The human OCT-4 isoforms differ in their ability to confer self-renewal J Biol Chem 281 44 2006 33554 33565
34. V. Kotoula, S.I. Papamichos, and A.F. Lambropoulos Revisiting OCT4 expression in peripheral blood mononuclear cells Stem Cells 26 1 2008 290 291
35. S.H. Chiou et al. Positive correlations of Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma Clin Cancer Res 14 13 2008 4085 4095
36. K.L. Brown, A. Maiti, and P. Johnson Role of sulfation in CD44-mediated hyaluronan binding induced by inflammatory mediators in human CD14(+) peripheral blood monocytes J Immunol 167 9 2001 5367 5374
37. R.S. Desai et al. Immunohistochemical expression of CD34 for characterization and quantification of mucosal vasculature and its probable role in malignant transformation of atrophic epithelium in oral submucous fibrosis Oral Oncol 46 7 2010 553 558
38. X.D. Wei et al. In vivo investigation of CD133 as a putative marker of cancer stem cells in Hep-2 cell line Head Neck 31 1 2009 94 101
39. E.J. Franzmann et al. Salivary soluble CD44: a potential molecular marker for head and neck cancer Cancer Epidemiol Biomarkers Prev 14 3 2005 735 739
40. N.M. Ravindranath, and C. Shuler Expression of complement restriction factors (CD46, CD55 & CD59) in head and neck squamous cell carcinomas J Oral Pathol Med 35 9 2006 560 567
41. A. Bengochea et al. Common dysregulation of Wnt/Frizzled receptor elements in human hepatocellular carcinoma Br J Cancer 99 1 2008 143 150
42. T.C. Camilli, and A.T. Weeraratna Striking the target in Wnt-y conditions: intervening in Wnt signaling during cancer progression Biochem Pharmacol 80 5 2010 702 711
43. C.F. Sala et al. Identification, gene structure, and expression of human frizzled-3 (FZD3) Biochem Biophys Res Commun 273 1 2000 27 34
44. Z.Y. Zeng et al. Gene expression profiling of nasopharyngeal carcinoma reveals the abnormally regulated Wnt signaling pathway Hum Pathol 38 1 2007 120 133
45. K. Melchior et al. The WNT receptor FZD7 contributes to self-renewal signaling of human embryonic stem cells Biol Chem 389 7 2008 897 903
46. K. Ueno et al. Frizzled-7 as a potential therapeutic target in colorectal cancer Neoplasia 10 7 2008 697 705
47. M. Mandal et al. Epithelial to mesenchymal transition in head and neck squamous carcinoma: association of Src activation with E-cadherin down-regulation, vimentin expression, and aggressive tumor features Cancer 112 9 2008 2088 2100
48. Y. Guo et al. Oct-4 is critical for survival/antiapoptosis of murine embryonic stem cells subjected to stress: effects associated with Stat3/survivin Stem Cells 26 1 2008 30 34
49. T. Hu et al. Octamer 4 small interfering RNA results in cancer stem cell-like cell apoptosis Cancer Res 68 16 2008 6533 6540