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Volumn 14, Issue 1, 2014, Pages

The effect of CD14 and TLR4 gene polimorphisms on asthma phenotypes in adult Turkish asthma patients: A genetic study

Author keywords

Asthma; Atopy; CD14; Eosinophil; Gen polymorphism; TLR4; Total IgE

Indexed keywords

CD14 ANTIGEN; IMMUNOGLOBULIN E; TOLL LIKE RECEPTOR 4;

EID: 84893705966     PISSN: None     EISSN: 14712466     Source Type: Journal    
DOI: 10.1186/1471-2466-14-20     Document Type: Article
Times cited : (19)

References (44)
  • 2
    • 0024417450 scopus 로고
    • Hay fever, hygiene, and householdsize
    • 10.1136/bmj.299.6710.1259, 1838109, 2513902
    • Strachan DP. Hay fever, hygiene, and householdsize. BMJ 1989, 299(6710):1259-1260. 10.1136/bmj.299.6710.1259, 1838109, 2513902.
    • (1989) BMJ , vol.299 , Issue.6710 , pp. 1259-1260
    • Strachan, D.P.1
  • 4
    • 0030666222 scopus 로고    scopus 로고
    • Innate immunity: the virtues of a nonclonal system of recognition
    • 10.1016/S0092-8674(00)80412-2, 9363937
    • Medzhitov R, Janeway CA. Innate immunity: the virtues of a nonclonal system of recognition. Cell 1997, 91(3):295-298. 10.1016/S0092-8674(00)80412-2, 9363937.
    • (1997) Cell , vol.91 , Issue.3 , pp. 295-298
    • Medzhitov, R.1    Janeway, C.A.2
  • 5
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • 10.1038/32588, 9521319
    • Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998, 392(6673):245-252. 10.1038/32588, 9521319.
    • (1998) Nature , vol.392 , Issue.6673 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 6
    • 0033913407 scopus 로고    scopus 로고
    • Molecular events of bacterial-induced maturation of dendritic cells
    • 10.1023/A:1006629328178, 10941823
    • Rescigno M, Granucci F, Ricciardi-Castagnoli P. Molecular events of bacterial-induced maturation of dendritic cells. J Clin Immunol 2000, 20(3):161-166. 10.1023/A:1006629328178, 10941823.
    • (2000) J Clin Immunol , vol.20 , Issue.3 , pp. 161-166
    • Rescigno, M.1    Granucci, F.2    Ricciardi-Castagnoli, P.3
  • 7
    • 42149153395 scopus 로고    scopus 로고
    • Toll-like receptors and CD14 genes polymorphisms and susceptibility to asthma in Tunisian children
    • 10.1111/j.1399-0039.2008.01011.x, 18312481
    • Lachheb J, Dhifallah IB, Chelbi H, Hamzaoui K, Hamzaoui A. Toll-like receptors and CD14 genes polymorphisms and susceptibility to asthma in Tunisian children. Tissue Antigens 2008, 71(5):417-25. 10.1111/j.1399-0039.2008.01011.x, 18312481.
    • (2008) Tissue Antigens , vol.71 , Issue.5 , pp. 417-425
    • Lachheb, J.1    Dhifallah, I.B.2    Chelbi, H.3    Hamzaoui, K.4    Hamzaoui, A.5
  • 8
    • 84859882630 scopus 로고    scopus 로고
    • Toll-like receptor 2 and Toll-like receptor 4 polymorphisms and susceptibility to asthma and allergic rhinitis: a case-control analysis
    • Hussein YM, Awad HA, Shalaby SM, Ali AS, Alzahrani SS. Toll-like receptor 2 and Toll-like receptor 4 polymorphisms and susceptibility to asthma and allergic rhinitis: a case-control analysis. Cell Immunol 2012, 274(1-2):34-38.
    • (2012) Cell Immunol , vol.274 , Issue.1-2 , pp. 34-38
    • Hussein, Y.M.1    Awad, H.A.2    Shalaby, S.M.3    Ali, A.S.4    Alzahrani, S.S.5
  • 9
    • 63349099534 scopus 로고    scopus 로고
    • Epidemiological Study on the Genetics and Environment of Asthma, Bronchial Hyperresponsiveness, and Atopy (EGEA) Cooperative Group: CD14 and toll-like receptor gene polymorphisms, country living, and asthma in adults
    • 10.1164/rccm.200810-1533OC, 19096003
    • Smit LA, Siroux V, Bouzigon E, Oryszczyn MP, Lathrop M, Demenais F, Kauffmann F. Epidemiological Study on the Genetics and Environment of Asthma, Bronchial Hyperresponsiveness, and Atopy (EGEA) Cooperative Group: CD14 and toll-like receptor gene polymorphisms, country living, and asthma in adults. Am J Respir Crit Care Med 2009, 179(5):363-8. 10.1164/rccm.200810-1533OC, 19096003.
    • (2009) Am J Respir Crit Care Med , vol.179 , Issue.5 , pp. 363-368
    • Smit, L.A.1    Siroux, V.2    Bouzigon, E.3    Oryszczyn, M.P.4    Lathrop, M.5    Demenais, F.6    Kauffmann, F.7
  • 10
    • 57149107350 scopus 로고    scopus 로고
    • Gene-specific control of the TLR-induced inflammatory response
    • 10.1016/j.clim.2008.08.015, 3252731, 18964303
    • Foster SL, Medzhitov R. Gene-specific control of the TLR-induced inflammatory response. Clin Immunol 2009, 130(1):7-15. 10.1016/j.clim.2008.08.015, 3252731, 18964303.
    • (2009) Clin Immunol , vol.130 , Issue.1 , pp. 7-15
    • Foster, S.L.1    Medzhitov, R.2
  • 12
    • 0033129061 scopus 로고    scopus 로고
    • A polymorphism in the 5' flanking region of the CD14 gene is associated with circulating soluble CD14 levels and with total serum Immunoglobulin E
    • 10.1165/ajrcmb.20.5.3494, 10226067
    • Baldini M, Lohman IC, Halonen M, Erickson RP, Holt PG, Martinez FD. A polymorphism in the 5' flanking region of the CD14 gene is associated with circulating soluble CD14 levels and with total serum Immunoglobulin E. Am J Respir Cell Mol Biol 1999, 20(5):976-983. 10.1165/ajrcmb.20.5.3494, 10226067.
    • (1999) Am J Respir Cell Mol Biol , vol.20 , Issue.5 , pp. 976-983
    • Baldini, M.1    Lohman, I.C.2    Halonen, M.3    Erickson, R.P.4    Holt, P.G.5    Martinez, F.D.6
  • 13
    • 27844508633 scopus 로고    scopus 로고
    • The effect of polymorphisms at the CD14 promoter and the TLR4 gene on asthma phenotypes in Turkish children with asthma
    • 10.1111/j.1398-9995.2005.00874.x, 16266379
    • Saçkesen C, Karaaslan C, Keskin O, Tokol N, Tahan F, Civelek E, Soyer OU, Adalioglu G, Tuncer A, Birben E, Oner C, Kalayci O. The effect of polymorphisms at the CD14 promoter and the TLR4 gene on asthma phenotypes in Turkish children with asthma. Allergy 2005, 60(12):1485-1492. 10.1111/j.1398-9995.2005.00874.x, 16266379.
    • (2005) Allergy , vol.60 , Issue.12 , pp. 1485-1492
    • Saçkesen, C.1    Karaaslan, C.2    Keskin, O.3    Tokol, N.4    Tahan, F.5    Civelek, E.6    Soyer, O.U.7    Adalioglu, G.8    Tuncer, A.9    Birben, E.10    Oner, C.11    Kalayci, O.12
  • 15
    • 79960073243 scopus 로고    scopus 로고
    • Association of CD14-260 (-159) C > T and asthma: a systematic review and meta-analysis
    • doi:10.1186/1471-2350-12-93, 3148550, 21745379
    • Zhao L, Bracken MB. Association of CD14-260 (-159) C > T and asthma: a systematic review and meta-analysis. BMC Med Genet 2011, 12:93. doi:10.1186/1471-2350-12-93, 3148550, 21745379.
    • (2011) BMC Med Genet , vol.12 , pp. 93
    • Zhao, L.1    Bracken, M.B.2
  • 16
    • 73449086493 scopus 로고    scopus 로고
    • Global Initiative for Asthma (GINA)
    • Global Initiative for Asthma (GINA) Global strategy for asthma management and prevention 2012, http://www.ginasthma.org, Global Initiative for Asthma (GINA).
    • (2012) Global strategy for asthma management and prevention
  • 18
    • 0028230946 scopus 로고
    • Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations
    • 10.1126/science.8178175, 8178175
    • Marsh DG, Neely JD, Breazeale DR, Ghosh B, Freidhoff LR, Ehrlich-Kautzky E, Schou C, Krishnaswamy G, Beaty TH. Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations. Science 1994, 264(5162):1152-1156. 10.1126/science.8178175, 8178175.
    • (1994) Science , vol.264 , Issue.5162 , pp. 1152-1156
    • Marsh, D.G.1    Neely, J.D.2    Breazeale, D.R.3    Ghosh, B.4    Freidhoff, L.R.5    Ehrlich-Kautzky, E.6    Schou, C.7    Krishnaswamy, G.8    Beaty, T.H.9
  • 19
    • 0035889904 scopus 로고    scopus 로고
    • A common single nucleotide polymorphism in the CD14 promoter decreases the affinity of Sp protein binding and enhances transcriptional activity
    • LeVan TD, Bloom JW, Bailey TJ, Karp CL, Halonen M, Martinez FD, et al. A common single nucleotide polymorphism in the CD14 promoter decreases the affinity of Sp protein binding and enhances transcriptional activity. J Immunol 2001, 167:5838-5844.
    • (2001) J Immunol , vol.167 , pp. 5838-5844
    • LeVan, T.D.1    Bloom, J.W.2    Bailey, T.J.3    Karp, C.L.4    Halonen, M.5    Martinez, F.D.6
  • 20
    • 2342622087 scopus 로고    scopus 로고
    • A promoter polymorphism in the CD14 gene is associated with elevated levels of soluble CD14 but not with IgE or atopic diseases
    • 10.1111/j.1398-9995.2004.00439.x, 15080833
    • Kabesch M, Hasemann K, Schickinger V, Tzotcheva I, Bohnert A, Carr D, et al. A promoter polymorphism in the CD14 gene is associated with elevated levels of soluble CD14 but not with IgE or atopic diseases. Allergy 2004, 59:520-525. 10.1111/j.1398-9995.2004.00439.x, 15080833.
    • (2004) Allergy , vol.59 , pp. 520-525
    • Kabesch, M.1    Hasemann, K.2    Schickinger, V.3    Tzotcheva, I.4    Bohnert, A.5    Carr, D.6
  • 23
    • 33751289924 scopus 로고    scopus 로고
    • Polymorphisms of the CD14 gene and atopic phenotypes in Czech patients with IgE mediated allergy
    • 10.1007/s10038-006-0050-0, 17003960
    • Bucková D, Hollá LI, Znojil V, Vasků A. Polymorphisms of the CD14 gene and atopic phenotypes in Czech patients with IgE mediated allergy. J Hum Genet 2006, 51(11):977-983. 10.1007/s10038-006-0050-0, 17003960.
    • (2006) J Hum Genet , vol.51 , Issue.11 , pp. 977-983
    • Bucková, D.1    Hollá, L.I.2    Znojil, V.3    Vasků, A.4
  • 24
    • 31544450586 scopus 로고    scopus 로고
    • Association of CD14 promoter polymorphisms and soluble CD14 levels in mite allergen sensitization of children in Taiwan
    • 10.1007/s10038-005-0323-z, 16292464
    • Tan CY, Chen YL, Wu LS, Liu CF, Chang WT, Wang JY. Association of CD14 promoter polymorphisms and soluble CD14 levels in mite allergen sensitization of children in Taiwan. J Hum Genet 2006, 51(1):59-67. 10.1007/s10038-005-0323-z, 16292464.
    • (2006) J Hum Genet , vol.51 , Issue.1 , pp. 59-67
    • Tan, C.Y.1    Chen, Y.L.2    Wu, L.S.3    Liu, C.F.4    Chang, W.T.5    Wang, J.Y.6
  • 25
    • 34447126839 scopus 로고    scopus 로고
    • CD14, endotoxin, and asthma risk: actions and interactions
    • 10.1513/pats.200702-035AW, 2647622, 17607003
    • Martinez FD. CD14, endotoxin, and asthma risk: actions and interactions. Proc Am Thorac Soc 2007, 4(3):221-225. 10.1513/pats.200702-035AW, 2647622, 17607003.
    • (2007) Proc Am Thorac Soc , vol.4 , Issue.3 , pp. 221-225
    • Martinez, F.D.1
  • 26
    • 33747143424 scopus 로고    scopus 로고
    • Endotoxin exposure, CD14, and allergic disease: an interaction between genes and the environment
    • 10.1164/rccm.200509-1380OC, 16614348
    • Simpson A, John SL, Jury F, Niven R, Woodcock A, Ollier WE, Custovic A. Endotoxin exposure, CD14, and allergic disease: an interaction between genes and the environment. Am J Respir Crit Care Med 2006, 174(4):386-392. 10.1164/rccm.200509-1380OC, 16614348.
    • (2006) Am J Respir Crit Care Med , vol.174 , Issue.4 , pp. 386-392
    • Simpson, A.1    John, S.L.2    Jury, F.3    Niven, R.4    Woodcock, A.5    Ollier, W.E.6    Custovic, A.7
  • 27
    • 33749342010 scopus 로고    scopus 로고
    • Gene-environment interactions with CD14 C-260 T and their relationship to total serum IgE levels in adults
    • 10.1016/j.jaci.2006.07.007, 17030237
    • Williams LK, McPhee RA, Ownby DR, Peterson EL, James M, Zoratti EM, Johnson CC. Gene-environment interactions with CD14 C-260 T and their relationship to total serum IgE levels in adults. J Allergy Clin Immunol 2006, 118(4):851-857. 10.1016/j.jaci.2006.07.007, 17030237.
    • (2006) J Allergy Clin Immunol , vol.118 , Issue.4 , pp. 851-857
    • Williams, L.K.1    McPhee, R.A.2    Ownby, D.R.3    Peterson, E.L.4    James, M.5    Zoratti, E.M.6    Johnson, C.C.7
  • 28
    • 0037329595 scopus 로고    scopus 로고
    • Learning from discrepancies: CD14 polymorphisms, atopy and the endotoxin switch
    • 10.1046/j.1365-2222.2003.01606.x, 12580903
    • Vercelli D. Learning from discrepancies: CD14 polymorphisms, atopy and the endotoxin switch. Clin Exp Allergy 2003, 33(2):153-155. 10.1046/j.1365-2222.2003.01606.x, 12580903.
    • (2003) Clin Exp Allergy , vol.33 , Issue.2 , pp. 153-155
    • Vercelli, D.1
  • 29
    • 75749084014 scopus 로고    scopus 로고
    • Association of the CD14 gene polymorphism C-159 T with allergic rhinitis
    • doi:10.2500/ajra.2010.24.3411
    • Han D, She W, Zhang L. Association of the CD14 gene polymorphism C-159 T with allergic rhinitis. Am J Rhinol Allergy 2010, 24(1):e1-3. doi:10.2500/ajra.2010.24.3411.
    • (2010) Am J Rhinol Allergy , vol.24 , Issue.1
    • Han, D.1    She, W.2    Zhang, L.3
  • 30
    • 8744248232 scopus 로고    scopus 로고
    • Suggestive evidence of association of C-159 T functional polymorphism of the CD14 gene with atopic asthma in northern and northwestern Indian populations
    • 10.1007/s00251-004-0721-y, 15378299
    • Sharma M, Batra J, Mabalirajan U, Goswami S, Ganguly D, Lahkar B, Bhatia NK, Kumar A, Ghosh B. Suggestive evidence of association of C-159 T functional polymorphism of the CD14 gene with atopic asthma in northern and northwestern Indian populations. Immunogenetics 2004, 56(7):544-547. 10.1007/s00251-004-0721-y, 15378299.
    • (2004) Immunogenetics , vol.56 , Issue.7 , pp. 544-547
    • Sharma, M.1    Batra, J.2    Mabalirajan, U.3    Goswami, S.4    Ganguly, D.5    Lahkar, B.6    Bhatia, N.K.7    Kumar, A.8    Ghosh, B.9
  • 31
    • 0242362649 scopus 로고    scopus 로고
    • Promoter polymorphisms of the CD14 gene are not associated with bronchial asthma in Caucasian children
    • 10.1046/j.1365-2370.2003.00414.x, 14641542
    • Heinzmann A, Dietrich H, Jerkic SP, Kurz T, Deichmann KA. Promoter polymorphisms of the CD14 gene are not associated with bronchial asthma in Caucasian children. Eur J Immunogenet 2003, 30(5):345-348. 10.1046/j.1365-2370.2003.00414.x, 14641542.
    • (2003) Eur J Immunogenet , vol.30 , Issue.5 , pp. 345-348
    • Heinzmann, A.1    Dietrich, H.2    Jerkic, S.P.3    Kurz, T.4    Deichmann, K.A.5
  • 32
    • 33645079412 scopus 로고    scopus 로고
    • CD14 promoter polymorphisms have no functional significance and are not associated with atopic phenotypes
    • 10.1097/01.fpc.0000197466.14340.0f, 16538169
    • Liang XH, Cheung W, Heng CK, Liu JJ, Li CW, Lim B, de Wang Y. CD14 promoter polymorphisms have no functional significance and are not associated with atopic phenotypes. Pharmacogenet Genomics 2006, 16(4):229-236. 10.1097/01.fpc.0000197466.14340.0f, 16538169.
    • (2006) Pharmacogenet Genomics , vol.16 , Issue.4 , pp. 229-236
    • Liang, X.H.1    Cheung, W.2    Heng, C.K.3    Liu, J.J.4    Li, C.W.5    Lim, B.6    de Wang, Y.7
  • 33
    • 0037326378 scopus 로고    scopus 로고
    • German multicenter allergy study group. Evaluation of the CD14 C-159 T polymorphism in the German multicenter allergy study cohort
    • 10.1046/j.1365-2222.2003.01549.x, 12580907
    • Sengler C, Haider A, Sommerfeld C, Lau S, Baldini M, Martinez F, Wahn U, Nickel R. German multicenter allergy study group. Evaluation of the CD14 C-159 T polymorphism in the German multicenter allergy study cohort. Clin Exp Allergy 2003, 33(2):166-169. 10.1046/j.1365-2222.2003.01549.x, 12580907.
    • (2003) Clin Exp Allergy , vol.33 , Issue.2 , pp. 166-169
    • Sengler, C.1    Haider, A.2    Sommerfeld, C.3    Lau, S.4    Baldini, M.5    Martinez, F.6    Wahn, U.7    Nickel, R.8
  • 36
    • 33749174130 scopus 로고    scopus 로고
    • The effect of CD14-C159T genotypes on the cytokine response to endotoxin by peripheral blood mononuclear cells from asthmatic children
    • 10.1016/S1081-1206(10)60796-X, 17042137
    • Keskin O, Birben E, Sackesen C, Soyer OU, Alyamac Ȩ Karaaslan C, Tokol N, Ercan H, Kalayci O. The effect of CD14-C159T genotypes on the cytokine response to endotoxin by peripheral blood mononuclear cells from asthmatic children. Ann Allergy Asthma Immunol 2006, 97(3):321-328. 10.1016/S1081-1206(10)60796-X, 17042137.
    • (2006) Ann Allergy Asthma Immunol , vol.97 , Issue.3 , pp. 321-328
    • Keskin, O.1    Birben, E.2    Sackesen, C.3    Soyer, O.U.4    Alyamac Ȩ Karaaslan, C.5    Tokol, N.6    Ercan, H.7    Kalayci, O.8
  • 37
    • 20444500048 scopus 로고    scopus 로고
    • Evaluation of CD14/-260 polymorphism and house dust endotoxin exposure in the Barbados asthma genetics study
    • 10.1016/j.jaci.2005.03.001, 15940135
    • Zambelli-Weiner A, Ehrlich E, Stockton ML, Grant AV, Zhang S, Levett PN, Beaty TH, Barnes KC. Evaluation of CD14/-260 polymorphism and house dust endotoxin exposure in the Barbados asthma genetics study. J Allergy Clin Immunol 2005, 115(6):1203-1209. 10.1016/j.jaci.2005.03.001, 15940135.
    • (2005) J Allergy Clin Immunol , vol.115 , Issue.6 , pp. 1203-1209
    • Zambelli-Weiner, A.1    Ehrlich, E.2    Stockton, M.L.3    Grant, A.V.4    Zhang, S.5    Levett, P.N.6    Beaty, T.H.7    Barnes, K.C.8
  • 40
    • 84864466880 scopus 로고    scopus 로고
    • Toll-like receptor gene polymorphisms are associated with allergic rhinitis: a case control study
    • 3459792, 22857391
    • Nilsson D, Andiappan AK, Halldén C, De Yun W, Säll T, Tim CF, Cardell LO. Toll-like receptor gene polymorphisms are associated with allergic rhinitis: a case control study. BMC Med Genet 2012, 13:66. 3459792, 22857391.
    • (2012) BMC Med Genet , vol.13 , pp. 66
    • Nilsson, D.1    Andiappan, A.K.2    Halldén, C.3    De Yun, W.4    Säll, T.5    Tim, C.F.6    Cardell, L.O.7
  • 41
    • 80051707475 scopus 로고    scopus 로고
    • Polymorphisms in toll-like receptor 4 gene are associated with asthma severity but not susceptibility in a Chinese Han population
    • Zhang Q, Qian FH, Zhou LF, Wei GZ, Jin GF, Bai JL, Yin KS. Polymorphisms in toll-like receptor 4 gene are associated with asthma severity but not susceptibility in a Chinese Han population. J Investig Allergol Clin Immunol 2011, 21(5):370-377.
    • (2011) J Investig Allergol Clin Immunol , vol.21 , Issue.5 , pp. 370-377
    • Zhang, Q.1    Qian, F.H.2    Zhou, L.F.3    Wei, G.Z.4    Jin, G.F.5    Bai, J.L.6    Yin, K.S.7


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