The effect of CD14-C159T genotypes on the cytokine response to endotoxin by peripheral blood mononuclear cells from asthmatic children

Annals of Allergy, Asthma and Immunology

Volumn 97, Issue 3, 2006, Pages 321-328

  Keskin, Özlem ^a   Birben, Esra ^a   Saçkesen, Cansin ^a   Soyer, Özge U ^a   Alyamaç, Evrim ^a   Karaaslan, Çaǧatay ^a   Tokol, Nihan ^a   Ercan, Hülya ^a   Kalayci, Omer ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; CD159T ANTIGEN; CONCANAMYCIN A; CYTOKINE; ENDOTOXIN; GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 4; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ANALYSIS OF COVARIANCE; ARTICLE; ASTHMA; CD159T GENE; CHILD; CLINICAL ARTICLE; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE; GENE LOCUS; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; INFLAMMATORY CELL; LYMPHOCYTE ACTIVATION; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DETERMINATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUPERNATANT;

EID: 33749174130     PISSN: 10811206     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1081-1206(10)60796-X     Document Type: Article

References (42)

1. von Hertzen LC, Haahtela T. Asthma and atopy-the price of affluence? Allergy. 2004;59:124-137.
2. Strachan DP. Hay fever, hygiene, and household size. BMJ. 1989;299:1259-1260.
3. Martinez FD. Role of viral infections in the inception of asthma and allergies during childhood: could they be protective? Thorax. 1994;49:1189-1191.
4. Holt PG. Environmental factors and primary T-cell sensitisation to inhalant allergens: reappraisal of the role of infections and air pollution. Pediatr Allergy Immunol. 1995;6:1-10.
5. Braun-Fahrländer C. Environmental exposure to endotoxin and other microbial products and the decreased risk of childhood atopy: evaluating developments since April 2002. Curr Opin Allergy Clin Immunol. 2003;3:325-329.
6. Rizzo MC, Naspitz CK, Fernandez-Caldas E, et al. Endotoxin exposure and symptoms in asthmatic children. Pediatr Allergy Immunol. 1997;8:121-126.
7. Michel O. Role of lipopolysaccharide (LPS) in asthma and other pulmonary conditions. J Endotoxin Res. 2003;9:293-300.
8. Michel O, Kips J, Duchateau J, et al. Severity of asthma is related to endotoxin in house dust. Am J Respir Crit Care Med. 1996;154:1641-1646.
9. Brass DM, Savov JD, Whitehead GS, et al. LPS binding protein is important in the airway response to inhaled endotoxin. J Allergy Clin Immunol. 2004;114:586-592.
10. Baldini M, Lohman IC, Halonen M, et al. A Polymorphism in the 5′ flanking region of the CD14 gene is associated with circulating soluble CD14 levels and with total serum immunoglobulin E. Am J Respir Cell Mol Biol. 1999;20:976-983.
11. LeVan TD, Bloom JW, Bailey TJ, et al. A common single nucleotide polymorphism in the CD14 promoter decreases the affinity of Sp protein binding and enhances transcriptional activity. J Immunol. 2001;167:5838-5844.
12. Arbour NC, Lorenz E, Schutte BC, et al. TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat Genet. 2000;25:187-191.
13. Leung TF, Tang NL, Sung YM, et al. The C-159T polymorphism in the CD14 promoter is associated with serum total IgE concentration in atopic Chinese children. Pediatr Allergy Immunol. 2003;14:255-260.
14. Koppelman GH, Reijmerink NE, Colin Stine O, et al. Association of a promoter polymorphism of the CD14 gene and atopy. Am J Respir Crit Care Med. 2001;163:965-969.
15. Saçkesen C, Karaaslan C, Keskin O, et al. The effect of polymorphisms at the CD14 promoter and the TLR4 gene on asthma phenotypes in Turkish children with asthma. Allergy. 2005;60:1485-1492.
16. Edwards-Smith CJ, Jonsson JR, Purdie DM, et al. Interleukin-10 promoter polymorphism predicts initial response of chronic hepatitis C to interferon alfa. Hepatology. 1999;30:526-530.
17. Kalayci O, Birben E, Tinari N, et al. Role of 90K protein in asthma and TH2-type cytokine expression. Ann Allergy Asthma Immunol. 2004;93:485-492.
18. Punnonen J, de Waal Malefyt R, van Vlasselaer P, et al. IL-10 and viral IL-10 prevent IL-4-induced IgE synthesis by inhibiting the accessory cell function of monocytes. J Immunol. 1993;151:1280-1289.
19. Akdis CA, Blesken T, Akdis M, et al. Role of interleukin 10 in specific immunotherapy. J Clin Invest. 1998;102:98-106.
20. Berkman N, John M, Roesems G, et al. Inhibition of macrophage inflammatory protein-1 by interleukin-10: Differential sensitivities in human blood monocytes and alveolar macrophages. J Immunol. 1995;155:4412-4418.
21. Yssel H, De Waal Malefyt R, Roncarolo, MG, et al. IL-10 is produced CD4 T cell clones and peripheral blood T cells. J Immunol. 1992;149:2378-2384.
22. Tomita K, Lim S, Hanazawa T, et al. Attenuated production of intracellular IL-10 and IL-12 in monocytes from patients with severe asthma. Clin Immunol. 2002;102:258-266.
23. Creery D, Angel JB, Aucoin S, et al. Nef protein of human immunodeficiency virus and lipopolysaccharide induce expression of CD14 on human monocytes through differential utilization of interleukin-10. Clin Diagnostic Lab Immunol. 2002;9:1212-1221.
24. Schippers EF, van 't Veer C, van Voorden S, et al. IL-10 and toll-like receptor-4 polymorphisms and the in vivo and ex vivo response to endotoxin. Cytokine. 2005;29:215-228.
25. Gauchat JF, Lebman DA, Coffman RL, et al. Structure and expression of germline epsilon transcripts in human B cells induced by interleukin 4 to switch to IgE production. J Exp Med. 1990;172:463-473.
26. DeKruyff RH, Turner T, Abrams JS, et al. Induction of human IgE synthesis by CD4+ T cell clones: requirement for interleukin 4 and low molecular weight B cell growth factor. J Exp Med. 1989;170:1477-1493.
27. Vercelli D, Jabara HH, Arai K, Geha RS. Induction of human IgE synthesis requires interleukin 4 and T/B cell interactions involving the T cell receptor/CD3 complex and MHC class II antigens. J Exp Med. 1989;169:1295-1307.
28. Gascan H, Gauchat JF, Roncarolo MG, et al. Human B cell clones can be induced to proliferate and to switch to IgE and IgG4 synthesis by interleukin 4 and a signal provided by activated CD4+ T cell clones J Exp Med. 1991;173:747-750.
29. Borish L, Mascali JJ, Dishuck J, et al. Detection of alveolar macrophage-derived IL-1 beta in asthma. Inhibition with corticosteroids. J Immunol. 1992;149:3078-3082.
30. Pujol JL, Cosso B, Daures JP, et al. Interleukin-1 secretion by alveolar macrophages from patients with bronchial asthma. Int Arch Allergy Appl Immunol. 1990;91:207-210.
31. Jansky L, Reymanova P, Kopecky J. Dynamics of cytokine production in human peripheral blood mononuclear cells stimulated by LPS or infected by Borrelia. Physiol Res. 2003;52:593-598.
32. Cavaillon JM, Fitting C, Haeffner-Cavaillon N, et al. Cytokine response by monocytes and macrophages to free and lipoprotein-bound lipopolysaccharide. Infect Immun. 1990;58:2375-2382.
33. De Groote D, Zangerle PF, Gevaert Y, et al. Direct stimulation of cytokines (IL-1 beta, TNF-alpha, IL-6, IL-2, IFN-gamma and GM-CSF) in whole blood I: comparison with isolated PBMC stimulation, Cytokine. 1992;4:239-248.
34. Flegel WA, Wolpl A, Mannel DN, Northoff H. Inhibition of endotoxin-induced activation of human monocytes by human lipoproteins. Infect Immun. 1989;57:2237-2245.
35. Dinarello CA. Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist. Int Rev Immunol. 1998;16:457-499.
36. Heumann D, Glauser MP, Calandra T. Molecular basis of host-pathogen interaction in septic shock. Curr Opin Microbiol. 1998;1:49-55.
37. Haziot A, Ferrero E, Kontgen F, et al. Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice. Immunity. 1996;4:407-414.
38. Gibot S, Cariou A, Drouet L, et al. Association between a genomic polymorphism within the CD14 locus and septic shock susceptibility and mortality rate. Crit Care Med. 2002;30:969-973.
39. Wood LJ, Sehmi R, Gauvreau GM, et al. An inhaled corticosteroid, budesonide, reduces baseline but not allergen-induced increases in bone marrow inflammatory cell progenitors in asthmatic subjects. Am J Respir Crit Care Med. 1999;159:1457-1463.
40. Durham SR, Gould HJ, Thienes CP, et al. Expression of epsilon germ-line gene transcripts and mRNA for the epsilon heavy chain of IgE in nasal B cells and the effects of topical corticosteroid. Eur J Immunol. 1997;27:2899-2906.
41. Ohrui T, Funayama T, Sekizawa K, et al. Effects of inhaled beclomethasone dipropionate on serum IgE levels and clinical symptoms in atopic asthma. Clin Exp Allergy. 1999;29:357-361.
42. Corne J. Do inhaled corticosteroids reduce serum IgE levels? the answer is maybe but how relevant is the question? Clin Exp Allergy. 1999;29:294-297.