Cellular bioenergetics changes in magnocellular neurons may affect copeptin expression in the late phase of sepsis

Journal of Neuroimmunology

Volumn 267, Issue 1-2, 2014, Pages 28-34

  Oliveira Pelegrin, Gabriela R ^a   Basso, Paulo J ^a   Rocha, Maria José A ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Apoptosis; Hypoxia induced factor 1 ; Interleukin 1 ; Nitric oxide synthase; Oxidative stress; Supraoptic nucleus

Indexed keywords

ARGIPRESSIN; BIOLOGICAL MARKER; COPEPTIN; CYTOCHROME C; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 1BETA; LIPOCORTIN 5;

ANIMAL CELL; ARTICLE; BIOENERGY; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MAGNOCELLULAR NERVE CELL; MALE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SEPSIS;

APOPTOSIS; HYPOXIA-INDUCED FACTOR-1Α; INTERLEUKIN-1Β; NITRIC OXIDE SYNTHASE; OXIDATIVE STRESS; SUPRAOPTIC NUCLEUS;

ANIMALS; ANNEXIN A5; ARGININE VASOPRESSIN; CECUM; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; GENE EXPRESSION REGULATION; GLYCOPEPTIDES; HYPOTHALAMUS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MALE; NEURONS; NITRIC OXIDE SYNTHASE TYPE II; OPTIC CHIASM; RATS; RATS, WISTAR; RECEPTORS, INTERLEUKIN-1 TYPE I; RNA, MESSENGER; SEPSIS; STATISTICS, NONPARAMETRIC; TIME FACTORS;

EID: 84893686455     PISSN: 01655728     EISSN: 18728421     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2013.12.006     Document Type: Article

References (44)

1. Athayde L.A., Oliveira-Pelegrin G.R., Nomizo A., Faccioli L.H., Rocha M.J. Blocking central leukotrienes synthesis affects vasopressin release during sepsis. Neuroscience 2009, 160:829-836.
2. Barat C., Simpson L., Breslow E. Properties of human vasopressin precursor constructs: inefficient monomer folding in the absence of copeptin as a potential contributor to diabetes insipidus. Biochemistry 2004, 43:8191-8203.
3. Berg R.M., Moller K., Bailey D.M. Neuro-oxidative-nitrosative stress in sepsis. J. Cereb. Blood Flow Metab. 2011, 31:1532-1544.
4. Bruick R.K. Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:9082-9087.
5. Bustin S.A., Benes V., Garson J.A., Hellemans J., Huggett J., Kubista M., Mueller R., Nolan T., Pfaffl M.W., Shipley G.L., Vandesompele J., Wittwer C.T. The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin. Chem. 2009, 55:611-622.
6. Chavez J.C., Agani F., Pichiule P., LaManna J.C. Expression of hypoxia-inducible factor-1alpha in the brain of rats during chronic hypoxia. J. Appl. Physiol. 2000, 89:1937-1942.
7. Correa P.B., Pancoto J.A., de Oliveira-Pelegrin G.R., Carnio E.C., Rocha M.J. Participation of iNOS-derived NO in hypothalamic activation and vasopressin release during polymicrobial sepsis. J. Neuroimmunol. 2007, 183:17-25.
8. Erusalimsky J.D., Moncada S. Nitric oxide and mitochondrial signaling: from physiology to pathophysiology. Arterioscler. Thromb. Vasc. Biol. 2007, 27:2524-2531.
9. Green D.R. Apoptotic pathways: paper wraps stone blunts scissors. Cell 2000, 102:1-4.
10. Guix F.X., Uribesalgo I., Coma M., Munoz F.J. The physiology and pathophysiology of nitric oxide in the brain. Prog. Neurobiol. 2005, 76:126-152.
11. Holmes C.L., Patel B.M., Russell J.A., Walley K.R. Physiology of vasopressin relevant to management of septic shock. Chest 2001, 120:989-1002.
12. Kiang J.G., Tsen K.T. Biology of hypoxia. Chin. J. Physiol. 2006, 49:223-233.
13. Landry D.W., Levin H.R., Gallant E.M., Ashton R.C., Seo S., D'Alessandro D., Oz M.C., Oliver J.A. Vasopressin deficiency contributes to the vasodilation of septic shock. Circulation 1997, 95:1122-1125.
14. Lee J.H., Chan Y.H., Lai O.F., Puthucheary J. Vasopressin and copeptin levels in children with sepsis and septic shock. Intensive Care Med. 2013, 39:747-753.
15. Mander P., Brown G.C. Nitric oxide, hypoxia and brain inflammation. Biochem. Soc. Trans. 2004, 32:1068-1069.
16. Mander P., Borutaite V., Moncada S., Brown G.C. Nitric oxide from inflammatory-activated glia synergizes with hypoxia to induce neuronal death. J. Neurosci. Res. 2005, 79:208-215.
17. Martins T.F., Sorgi C.A., Faccioli L.H., Rocha M.J. Leukotriene synthesis inhibitor decreases vasopressin release in the early phase of sepsis. J. Neuroimmunol. 2011, 238:52-57.
18. Mignotte B., Vayssiere J.L. Mitochondria and apoptosis. Eur. J. Biochem. 1998, 252:1-15.
19. Morgenthaler N.G., Muller B., Struck J., Bergmann A., Redl H., Christ-Crain M. Copeptin, a stable peptide of the arginine vasopressin precursor, is elevated in hemorrhagic and septic shock. Shock 2007, 28:219-226.
20. Morgenthaler N.G., Struck J., Jochberger S., Dunser M.W. Copeptin: clinical use of a new biomarker. Trends Endocrinol. Metab. 2008, 19:43-49.
21. Nemzek J.A., Xiao H.Y., Minard A.E., Bolgos G.L., Remick D.G. Humane endpoints in shock research. Shock 2004, 21:17-25.
22. Oliveira-Pelegrin G.R., Ravanelli M.I., Branco L.G., Rocha M.J. Thermoregulation and vasopressin secretion during polymicrobial sepsis. Neuroimmunomodulation 2009, 16:45-53.
23. Oliveira-Pelegrin G.R., Aguila F.A., Basso P.J., Rocha M.J. Role of central NO-cGMP pathway in vasopressin and oxytocin gene expression during sepsis. Peptides 2010, 31:1847-1852.
24. Oliveira-Pelegrin G.R., de Azevedo S.V., Yao S.T., Murphy D., Rocha M.J. Central NOS inhibition differentially affects vasopressin gene expression in hypothalamic nuclei in septic rats. J. Neuroimmunol. 2010, 227:80-86.
25. Oliveira-Pelegrin G.R., Basso P.J., Soares A.S., Martinez M.R., Riester K.D., Rocha M.J. Cleaved caspase-3 expression in hypothalamic magnocellular neurons may affect vasopressin secretion during experimental polymicrobial sepsis. J. Neuroimmunol. 2013, 258:10-16.
26. Palkovits M. Isolated removal of hypothalamic or other brain nuclei of the rat. Brain Res. 1973, 59:449-450.
27. Pancoto J.A., Correa P.B., Oliveira-Pelegrin G.R., Rocha M.J. Autonomic dysfunction in experimental sepsis induced by cecal ligation and puncture. Auton. Neurosci. 2008, 138:57-63.
28. Peinnequin A., Mouret C., Birot O., Alonso A., Mathieu J., Clarencon D., Agay D., Chancerelle Y., Multon E. Rat pro-inflammatory cytokine and cytokine related mRNA quantification by real-time polymerase chain reaction using SYBR green. BMC Immunol. 2004, 5:3.
29. Pfaffl M.W., Horgan G.W., Dempfle L. Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res. 2002, 30:e36.
30. Rivest S., Lacroix S., Vallieres L., Nadeau S., Zhang J., Laflamme N. How the blood talks to the brain parenchyma and the paraventricular nucleus of the hypothalamus during systemic inflammatory and infectious stimuli. Proc. Soc. Exp. Biol. Med. 2000, 223:22-38.
31. Seligman R., Papassotiriou J., Morgenthaler N.G., Meisner M., Teixeira P.J. Copeptin, a novel prognostic biomarker in ventilator-associated pneumonia. Crit. Care 2008, 12:R11.
32. Sharp F.R., Bernaudin M. HIF1 and oxygen sensing in the brain. Nat. Rev. Neurosci. 2004, 5:437-448.
33. Sharshar T., Carlier R., Blanchard A., Feydy A., Gray F., Paillard M., Raphael J.C., Gajdos P., Annane D. Depletion of neurohypophyseal content of vasopressin in septic shock. Crit. Care Med. 2002, 30:497-500.
34. Sharshar T., Blanchard A., Paillard M., Raphael J.C., Gajdos P., Annane D. Circulating vasopressin levels in septic shock. Crit. Care Med. 2003, 31:1752-1758.
35. Sharshar T., Gray F., Lorin de la Grandmaison G., Hopkinson N.S., Ross E., Dorandeu A., Orlikowski D., Raphael J.C., Gajdos P., Annane D. Apoptosis of neurons in cardiovascular autonomic centres triggered by inducible nitric oxide synthase after death from septic shock. Lancet 2003, 362:1799-1805.
36. Sola S., Morgado A.L., Rodrigues C.M. Death receptors and mitochondria: two prime triggers of neural apoptosis and differentiation. Biochim. Biophys. Acta 2013, 1830:2160-2166.
37. Sonneville R., Guidoux C., Barrett L., Viltart O., Mattot V., Polito A., Siami S., de la Grandmaison G.L., Blanchard A., Singer M., Annane D., Gray F., Brouland J.P., Sharshar T. Vasopressin synthesis by the magnocellular neurons is different in the supraoptic nucleus and in the paraventricular nucleus in human and experimental septic shock. Brain Pathol. 2010, 20:613-622.
38. Struck J., Morgenthaler N.G., Bergmann A. Copeptin, a stable peptide derived from the vasopressin precursor, is elevated in serum of sepsis patients. Peptides 2005, 26:2500-2504.
39. Swanson L.W. Brain Maps: Structure of the Rat Brain 1998, Elsevier Science, Amsterdam.
40. Tam Z.Y., Cai Y.H., Gunawan R. Elucidating cytochrome C release from mitochondria: insights from an in silico three-dimensional model. Biophys. J. 2010, 99:3155-3163.
41. van Engeland M., Nieland L.J., Ramaekers F.C., Schutte B., Reutelingsperger C.P. Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure. Cytometry 1998, 31:1-9.
42. Wong M.L., Bongiorno P.B., al-Shekhlee A., Esposito A., Khatri P., Licinio J. IL-1 beta, IL-1 receptor type I and iNOS gene expression in rat brain vasculature and perivascular areas. Neuroreport 1996, 7:2445-2448.
43. Wong M.L., Rettori V., al-Shekhlee A., Bongiorno P.B., Canteros G., McCann S.M., Gold P.W., Licinio J. Inducible nitric oxide synthase gene expression in the brain during systemic inflammation. Nat. Med. 1996, 2:581-584.
44. Wong M.L., Bongiorno P.B., Rettori V., McCann S.M., Licinio J. Interleukin (IL) 1beta, IL-1 receptor antagonist, IL-10, and IL-13 gene expression in the central nervous system and anterior pituitary during systemic inflammation: pathophysiological implications. Proc. Natl. Acad. Sci. U. S. A. 1997, 94:227-232.