Continuous cadmium exposure from weaning to maturity induces downregulation of ovarian follicle development-related SCF/c-kit gene expression and the corresponding changes of DNA methylation/microRNA pattern

Toxicology Letters

Volumn 225, Issue 3, 2014, Pages 367-377

  Weng, Shaozheng ^a   Wang, Wenxiang ^a   Li, Yuchen ^a   Li, Hong ^b   Lu, Xiaoli ^a   Xiao, Shihua ^a   Wu, Tingting ^a   Xie, Meimei ^a   Zhang, Wenchang ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

^b Department of Dermatology   (China)

Author keywords

C Kit; Cadmium; DNA methylation; Follicle; MicroRNA; Stem cell factor

Indexed keywords

BISULFITE; CADMIUM; CADMIUM CHLORIDE; DNA; MICRORNA; MICRORNA 221; MICRORNA 222; STEM CELL FACTOR; STEM CELL FACTOR RECEPTOR;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA METHYLATION; DOWN REGULATION; FEEDING; FEMALE; GENE EXPRESSION; MATURITY; NICK END LABELING; NONHUMAN; OVARY FOLLICLE DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; TRANSMISSION ELECTRON MICROSCOPY; WEANING; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; DRUG EFFECTS; GENETICS; METABOLISM; OVARY FOLLICLE; RANDOMIZATION; TOXICITY; ULTRASTRUCTURE; WISTAR RAT;

ANIMALS; APOPTOSIS; CADMIUM CHLORIDE; DNA METHYLATION; DOWN-REGULATION; FEMALE; IN SITU NICK-END LABELING; MICRORNAS; MICROSCOPY, ELECTRON, TRANSMISSION; OVARIAN FOLLICLE; PROTO-ONCOGENE PROTEINS C-KIT; RANDOM ALLOCATION; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; STEM CELL FACTOR;

EID: 84893684118     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2014.01.012     Document Type: Article

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