Emodin can induce K562 cells to erythroid differentiation and improve the expression of globin genes

Molecular and Cellular Biochemistry

Volumn 382, Issue 1-2, 2013, Pages 127-136

  Ma, Yan Ni ^a   Chen, Ming Tai ^a   Wu, Zhi Kui ^b   Zhao, Hua Lu ^a   Yu, Hai Chuan ^a   Yu, Jia ^a   Zhang, Jun Wu ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^b INSTITUTE OF CHINESE MATERIA MEDICA   (China)

Author keywords

Emodin; Erythroid differentiation; Globin; K562 cells

Indexed keywords

CD71 ANTIGEN; EMODIN; GLOBIN; GLYCOPHORIN A; HEMOGLOBIN ALPHA CHAIN; HEMOGLOBIN EPSILON CHAIN; HEMOGLOBIN GAMMA CHAIN; MESSENGER RNA; MICRORNA; MICRORNA 221; MICRORNA 222; PROTEIN; PROTEIN ALAS2; STEM CELL FACTOR RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CELL STRAIN K 562; CHINESE MEDICINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ERYTHROID CELL; ERYTHROPOIESIS; GENE EXPRESSION; HUMAN; HUMAN CELL; PROTEIN EXPRESSION;

CELL DIFFERENTIATION; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; EMODIN; ERYTHROID CELLS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, LEUKEMIC; GLOBINS; HEMOGLOBINS; HUMANS; K562 CELLS; NEOPLASM PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS; RNA, MESSENGER;

EID: 84884669903     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-013-1726-3     Document Type: Article

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