Effect and mechanism of cadmium on the progesterone synthesis of ovaries

Toxicology

Volumn 239, Issue 3, 2007, Pages 204-212

  Zhang, Wenchang ^a   Jia, Haimei ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Cadmium; Granulosa cells; P450 cholesterol side chain cleavage (P450scc); Progesterone; Steroidogenic acute regulatory protein (StAR)

Indexed keywords

CADMIUM; CADMIUM CHLORIDE; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); STEROIDOGENIC ACUTE REGULATORY PROTEIN;

ARTICLE; CONTROLLED STUDY; FEMALE; GRANULOSA CELL; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROGESTERONE RELEASE; PROGESTERONE SYNTHESIS; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; STEROIDOGENESIS;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ANIMALS; CADMIUM CHLORIDE; CELLS, CULTURED; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; FEMALE; GRANULOSA CELLS; INJECTIONS, SUBCUTANEOUS; OVARY; PHOSPHOPROTEINS; PROGESTERONE; PROGESTINS; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

BOVINAE; RATTUS; RATTUS NORVEGICUS;

EID: 34548418172     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2007.07.007     Document Type: Article

References (21)

1. Carcia-Morales P., Saceda M., Kenney N., et al. Effect of cadmium on estrogen receptor levels and estrogen-induced responses in human breast cancer cells. J. Biol. Chem. 269 24 (1994) 16896-16901
2. Clark B.J., Wells J., King S.R., and Stocco D.M. The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR). Biol. Chem. 269 (1994) 28314-28322
3. EPA, Agency EP.Ebdocrine Disruptor Screening Program. Available online: http://www.epa.gov/scipoli/oscpendo/edspoverview/index.htm, 2004.
4. Gang-Sui (Ed.), 2001. The Substructure and Clinical of Placenta Endocrine. p. 2.
5. Hua G., and Hong Tao L. StAR-the steroidogenic acute regulatory protein. Foreign Med.-Endocrinolog. 21 5 (2001) 266-268
6. Henson M.C., and Anderson M.B. The effects of cadmium on placental endocrine function. In: Pandalai S.G. (Ed). Recent Research Developments in Endocrinology (2000), Transworld Research Network, Trivandrum, India 37-47
7. Jolibois L.S., Shi W., George W.J., Henson M.C., and Anderson M.B. Cadmium accumulation and effects on progesterone release by cultured human trophoblast cells. Reprod. Toxicol. 13 (1999) 215-221
8. Kawaia M., Swana K.F., Greena A.E., Edwards D.E., Anderson M.B., and Henson M.C. Placental endocrine disruption induced by cadmium: effects on p450 cholesterol side-chain cleavage and 3β-hydroxysteroid dehydrogenase enzymes in cultured human trophoblasts. Biol. Reprod. 67 (2002) 178-183
9. LaVoie H.A., Singh D., and Hui Y.Y. Concerted regulation of the porcine steroidogenic acute regulatory protein gene promoter activity by follicle-stimulating hormone and insulin-like growth factor I in granulosa cells involves GATA-4 and CCAAT/enhancer binding protein β. Endocrinology 145 7 (2004) 3122-3134
10. Manna P.R., Kero J., Tena-Sempere M., Pakarinen P., Stocco D., and Huhtnniemi I.T. Assessment of mechanisms of thyroid hormone actionin mouse leydig cells: regulation of the steroidogenic acute regulatory protein, steroidogenesis, and luteinizing hormone receptor function. Endocrinology (printed in USA) 142 1 (2001) 319-331
11. Manna P.R., Dyson M.T., and Eubank D.W. Regulation of steroidogenesis and the steroidogenic acute regulatory protein by a member of the cAMP response-element binding protein family. Molec. Endocrinol. 16 1 (2002) 184-199
12. Manna P.R., Huhtaniemi2 I.T., and Stocco1 D.M. Detection of hCG responsive expression of the steroidogenic acute regulatory protein in mouse Leydig cells. Biol. Proced. 6 1 (2004) 83-93
13. Michael C., Hael C., Henson P., and Chedrese J. Endocrine disruption by cadmium, a common environmental toxicant with paradoxical effects on reproduction. Exp. Biol. Med. 229 (2004) 383-392
14. Paksy K., Varga B., Na'ray M., Olayos F., and Folly G. Altered ovarian progesterone secretion induced by cadmium fails to interfere with embryo transport in the oviduct of the rat. Reprod. Toxicol. 6 (1992) 77-83
15. Petrescu A.D., Gallegos A.M., and Okamura Y. Steroidogenic acute regulatory protein binds cholesterol and modulates mitochondrial membrane sterol domain dynamics. Biol. Chem. 276 40 (2001) 36970-36982 5
16. Piasek M., and Laskey J.W. Effects of in vitro cadmium exposure on ovarian steroidogenesis in rats. Appl. Toxicol. 19 (1999) 211-217
17. Piasek M., Blanua M., Kostial K., and Laskey J.W. Placental cadmium and progesterone concentrations in cigarette smokers. Reprod. Toxicol. 15 (2001) 673-681
18. Piasek M., Laskey J.W., Kostial R.K., and Blanusa M. Assessment of steroid disruption using cultures of whole ovary and/or placenta in rat and in human placental tissue. Int. Arch. Occup. Environ. Health 75 Suppl (2002) S36-S44
19. Smida A.D., and Cadmium X.P. Stimulates transcription of the cytochrome P450 side chain cleavage gene in genetically modified stable porcine granulosa cells. Toxicol. Biol. Reprod. 10 (2003) 25-31 1095.103.019000
20. Smida A.D., Valderrama X.P., Agostini M.C., Furlan M.A., and Chedrese J. Cadmium stimulates transcription of the cytochrome P450 side chain cleavage gene in genetically modified stable porcine granulosa cells. Biol. Reprod. 70 (2004) 25-31
21. Yang K., Julan L., and Rubio F. Cadmium reduces 11β-hydroxysteroid dehydrogenase type 2 activity and expression in human placental trophoblast cells. Am. J. Physiol. Endocrinol. Metab. 290 (2006) E135-E142