메뉴 건너뛰기




Volumn 472, Issue 2, 2014, Pages 396-404

Osteogenic gene expression correlates with development of heterotopic ossification in war wounds

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; CARTILAGE OLIGOMERIC MATRIX PROTEIN; COL11A1 PROTEIN; COL2A1 PROTEIN; COLL10A1; COLLAGEN TYPE 10; COLLAGEN TYPE 11; COLLAGEN TYPE 2; CSF2 PROTEIN; CSF3 PROTEIN; GELATINASE B; MESSENGER RNA; NEUTROPHIL COLLAGENASE; OSTEOGENIN; SMAD1 PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN A;

EID: 84893645277     PISSN: 0009921X     EISSN: 15281132     Source Type: Journal    
DOI: 10.1007/s11999-013-3325-8     Document Type: Article
Times cited : (64)

References (53)
  • 1
    • 51449105459 scopus 로고    scopus 로고
    • Biological basis of bone formation, remodeling, and repair - Part I: Biochemical signaling molecules
    • 1:CAS:528:DC%2BD1cXhtFWlurzL 18665803 10.1089/ten.teb.2008.0082
    • Allori RC, Sailon AM, Warren SM. Biological basis of bone formation, remodeling, and repair - part I: biochemical signaling molecules. Tissue Eng Part B Rev. 2008;14:259-273.
    • (2008) Tissue Eng Part B Rev. , vol.14 , pp. 259-273
    • Allori, R.C.1    Sailon, A.M.2    Warren, S.M.3
  • 3
    • 0015754154 scopus 로고
    • Ectopic ossification following total hip replacement. Incidence and a method of classification
    • 1:STN:280:DyaE2M7hsVylsA%3D%3D 4217797
    • Brooker AF, Bowerman JW, Robinson RA, Riley LHJ. Ectopic ossification following total hip replacement. Incidence and a method of classification. J Bone Joint Surg Am. 1973;55:1629-1632.
    • (1973) J Bone Joint Surg Am. , vol.55 , pp. 1629-1632
    • Brooker, A.F.1    Bowerman, J.W.2    Robinson, R.A.3    Riley, L.H.J.4
  • 4
    • 0042170047 scopus 로고    scopus 로고
    • Heterotopic ossification prophylaxis with indomethacin increases the risk of long-bone nonunion
    • 1:STN:280:DC%2BD3szlvFanug%3D%3D 12892193
    • Burd TA, Hughes MS, Anglen JO. Heterotopic ossification prophylaxis with indomethacin increases the risk of long-bone nonunion. J Bone Joint Surg Br. 2003;85:700-705.
    • (2003) J Bone Joint Surg Br. , vol.85 , pp. 700-705
    • Burd, T.A.1    Hughes, M.S.2    Anglen, J.O.3
  • 5
    • 0345305374 scopus 로고    scopus 로고
    • Angiogenesis and bone repair
    • 1:CAS:528:DC%2BD3sXptlCltbo%3D 14643161 10.1016/S1359-6446(03)02866-6
    • Carano RA, Filvaroff EH. Angiogenesis and bone repair. Drug Discov Today. 2003;8:980-989.
    • (2003) Drug Discov Today. , vol.8 , pp. 980-989
    • Carano, R.A.1    Filvaroff, E.H.2
  • 6
    • 0036137896 scopus 로고    scopus 로고
    • Macrophage cell lines produce osteoinductive signals that include bone morphogenetic protein-2
    • 1:CAS:528:DC%2BD38XktFeqsg%3D%3D 11792561 10.1016/S8756-3282(01)00638-X
    • Champagne CM, Takebe J, Offenbacher S, Cooper LF. Macrophage cell lines produce osteoinductive signals that include bone morphogenetic protein-2. Bone. 2002;30:26-31.
    • (2002) Bone. , vol.30 , pp. 26-31
    • Champagne, C.M.1    Takebe, J.2    Offenbacher, S.3    Cooper, L.F.4
  • 7
    • 12744274538 scopus 로고    scopus 로고
    • Heterotopic ossification in traumatic brain injury
    • 15668564 10.1097/01.PHM.0000151939.59660.B1
    • Chan KT. Heterotopic ossification in traumatic brain injury. Am J Phys Med Rehabil. 2005;84:145-146.
    • (2005) Am J Phys Med Rehabil. , vol.84 , pp. 145-146
    • Chan, K.T.1
  • 8
    • 42749086937 scopus 로고    scopus 로고
    • Heterotopic ossification after the Outerbridge-Kashiwagi procedure in the elbow
    • 10.1016/j.jse.2007.06.018
    • Chandrasenan J, Dias R, Lunn PG. Heterotopic ossification after the Outerbridge-Kashiwagi procedure in the elbow. J Shoulder Elbow Surg. 2008;17:15-17.
    • (2008) J Shoulder Elbow Surg. , vol.17 , pp. 15-17
    • Chandrasenan, J.1    Dias, R.2    Lunn, P.G.3
  • 9
    • 12344291865 scopus 로고    scopus 로고
    • Bone morphogenetic proteins
    • 1:CAS:528:DC%2BD2MXhtFWrsQ%3D%3D 15621726 10.1080/08977190412331279890
    • Chen D, zhao M, Mundy GR. Bone morphogenetic proteins. Growth Factors. 2004;22:233-241.
    • (2004) Growth Factors. , vol.22 , pp. 233-241
    • Chen, D.1    Zhao, M.2    Mundy, G.R.3
  • 10
    • 79961069198 scopus 로고    scopus 로고
    • Heterotopic ossification in complex orthopaedic combat wounds: Quantification and characterization of osteogenic precursor cell activity in traumatized muscle
    • 21776549
    • Davis TA, O'Brien FP, Anam K, Grijalva S, Potter BK, Elster EA. Heterotopic ossification in complex orthopaedic combat wounds: quantification and characterization of osteogenic precursor cell activity in traumatized muscle. J Bone Joint Surg Am. 2011;93:1122-1131.
    • (2011) J Bone Joint Surg Am. , vol.93 , pp. 1122-1131
    • Davis, T.A.1    O'Brien, F.P.2    Anam, K.3    Grijalva, S.4    Potter, B.K.5    Elster, E.A.6
  • 11
    • 20844450082 scopus 로고    scopus 로고
    • Fibrodysplasia ossificans progressiva (FOP), a disorder of ectopic osteogenesis, misregulates cell surface expression and trafficking of bmpria
    • 15940369 10.1359/JBMR.050305
    • de la Pena LS, Billings PC, Fiori JL, Ahn J, Kaplan FS, Shore EM. Fibrodysplasia ossificans progressiva (FOP), a disorder of ectopic osteogenesis, misregulates cell surface expression and trafficking of bmpria. J Bone Miner Res. 2005;20:1168-1176.
    • (2005) J Bone Miner Res. , vol.20 , pp. 1168-1176
    • De La Pena, L.S.1    Billings, P.C.2    Fiori, J.L.3    Ahn, J.4    Kaplan, F.S.5    Shore, E.M.6
  • 12
    • 0034457236 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factors and their receptors during osteoblast differentiation
    • 1:CAS:528:DC%2BD3cXlt1WnsrY%3D 10803575
    • Deckers MM, Karperien M, van der Bent C, Yamashita T, Papapoulos SE, Lowik CW. Expression of vascular endothelial growth factors and their receptors during osteoblast differentiation. Endocrinology. 2000;141:1667-1674.
    • (2000) Endocrinology. , vol.141 , pp. 1667-1674
    • Deckers, M.M.1    Karperien, M.2    Van Der Bent, C.3    Yamashita, T.4    Papapoulos, S.E.5    Lowik, C.W.6
  • 14
  • 17
    • 77951927951 scopus 로고    scopus 로고
    • Heterotopic ossification in wartime wounds
    • 20371008
    • Forsberg JA, Potter BK. Heterotopic ossification in wartime wounds. J Surg Orthop Adv. 2010;19:54-61.
    • (2010) J Surg Orthop Adv. , vol.19 , pp. 54-61
    • Forsberg, J.A.1    Potter, B.K.2
  • 18
    • 38849093307 scopus 로고    scopus 로고
    • A unique case of fibrodysplasia ossificans progressiva with an ACVR1 mutation, g356d, other than the common mutation (r206 h)
    • 10.1002/ajmg.a.32151
    • Furuya H, Ikezoe K, Wang L, Ohyagi Y, Motomura K, Fujii N, Kira J, Fukumaki Y. A unique case of fibrodysplasia ossificans progressiva with an ACVR1 mutation, g356d, other than the common mutation (r206 h). Am J Med Genet A. 2008;146:459-463.
    • (2008) Am J Med Genet A. , vol.146 , pp. 459-463
    • Furuya, H.1    Ikezoe, K.2    Wang, L.3    Ohyagi, Y.4    Motomura, K.5    Fujii, N.6    Kira, J.7    Fukumaki, Y.8
  • 20
    • 34548457296 scopus 로고    scopus 로고
    • Functional modeling of th EACVR1 (r206 h) mutation in fop
    • 17572636 10.1097/BLO.0b013e318126c049
    • Groppe JC, Shore EM, Kaplan FS. Functional modeling of th EACVR1 (r206 h) mutation in fop. Clin Orthop Relat Res. 2007;462:87-92.
    • (2007) Clin Orthop Relat Res. , vol.462 , pp. 87-92
    • Groppe, J.C.1    Shore, E.M.2    Kaplan, F.S.3
  • 23
    • 33748958488 scopus 로고    scopus 로고
    • Immunolocalization of vascular endothelial growth factor on intramuscular ectopic osteoinduction by bone morphogenetic protein-2
    • 1:CAS:528:DC%2BD28XhtVajsb7M 16857215 10.1016/j.lfs.2006.06.033
    • Kakudo N, Kusumoto K, Wang YB, Iguchi Y, Ogawa Y. Immunolocalization of vascular endothelial growth factor on intramuscular ectopic osteoinduction by bone morphogenetic protein-2. Life Sci. 2006;79:1847-1855.
    • (2006) Life Sci. , vol.79 , pp. 1847-1855
    • Kakudo, N.1    Kusumoto, K.2    Wang, Y.B.3    Iguchi, Y.4    Ogawa, Y.5
  • 24
    • 4644264945 scopus 로고    scopus 로고
    • Transgenic mice overexpressing BMP4 develop a fibrodysplasia ossificans progressiva (FOP)-like phenotype
    • 1:CAS:528:DC%2BD2cXptFSmtrg%3D 15466378 10.1016/S0002-9440(10)63372-X
    • Kan L, Hu M, Gomes WA, Kesler JA. Transgenic mice overexpressing BMP4 develop a fibrodysplasia ossificans progressiva (FOP)-like phenotype. Am J Pathol. 2004;165:1107-1115.
    • (2004) Am J Pathol. , vol.165 , pp. 1107-1115
    • Kan, L.1    Hu, M.2    Gomes, W.A.3    Kesler, J.A.4
  • 27
    • 0030768406 scopus 로고    scopus 로고
    • Comparison of human osteoblasts and osteogenic cells from heterotopic bone
    • 9308541 10.1097/00003086-199709000-00026
    • Kaysinger KK, Ramp WK, Lang GJ, Gruber HE. Comparison of human osteoblasts and osteogenic cells from heterotopic bone. Clin Orthop Relat Res. 1997;342:181-191.
    • (1997) Clin Orthop Relat Res. , vol.342 , pp. 181-191
    • Kaysinger, K.K.1    Ramp, W.K.2    Lang, G.J.3    Gruber, H.E.4
  • 28
    • 61549132911 scopus 로고    scopus 로고
    • Effect of local sequential VEGF and BMP-2 delivery on ectopic and orthotopic bone regeneration
    • 1:CAS:528:DC%2BD1MXjtFams7o%3D 19232714 10.1016/j.biomaterials.2009.01. 031
    • Kempen DH, Lu L, Heijink A, Hefferan TE, Creemers LB, Maran A, Yaszemski MJ, Dhert WJ. Effect of local sequential VEGF and BMP-2 delivery on ectopic and orthotopic bone regeneration. Biomaterials. 2009;30:2816-2825.
    • (2009) Biomaterials. , vol.30 , pp. 2816-2825
    • Kempen, D.H.1    Lu, L.2    Heijink, A.3    Hefferan, T.E.4    Creemers, L.B.5    Maran, A.6    Yaszemski, M.J.7    Dhert, W.J.8
  • 29
    • 49349087501 scopus 로고    scopus 로고
    • The expression of molecular mediators in the idiopathic cutaneous calcification and ossification
    • 18422975 10.1111/j.1600-0560.2007.00904.x
    • Kim SY, Choi HY, Myung KB, Choi YW. The expression of molecular mediators in the idiopathic cutaneous calcification and ossification. J Cutan Pathol. 2008;35:826-831.
    • (2008) J Cutan Pathol. , vol.35 , pp. 826-831
    • Kim, S.Y.1    Choi, H.Y.2    Myung, K.B.3    Choi, Y.W.4
  • 30
    • 0029039195 scopus 로고
    • Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia
    • 1:CAS:528:DyaK2MXmtV2hsr4%3D 7768934 10.1074/jbc.270.22.13333
    • Levy AP, Levy NS, Wegner S, Goldberg MA. Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia. J Biol Chem. 1995;270:13333-13340.
    • (1995) J Biol Chem. , vol.270 , pp. 13333-13340
    • Levy, A.P.1    Levy, N.S.2    Wegner, S.3    Goldberg, M.A.4
  • 31
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative pcr and the 2(-delta delta c[t]) method
    • 1:CAS:528:DC%2BD38XhtFelt7s%3D 11846609 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative pcr and the 2(-delta delta c[t]) method. Methods. 2001;25:402-408.
    • (2001) Methods. , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 33
    • 0027230099 scopus 로고
    • A 24-base-pair sequence 3′ to the human erythropoetin gene contains a hypoxia-responsive transcriptional enhancer
    • 1:CAS:528:DyaK3sXktVansb4%3D 8387202 10.1073/pnas.90.9.3928
    • Madan A, Curtin PT. A 24-base-pair sequence 3′ to the human erythropoetin gene contains a hypoxia-responsive transcriptional enhancer. Proc Natl Acad Sci USA. 1993;90:3928-3932.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3928-3932
    • Madan, A.1    Curtin, P.T.2
  • 34
    • 0028252324 scopus 로고
    • Prophylactic indomethacin for the prevention of heterotopic ossification after acetabular fracture surgery in high-risk patients
    • 1:STN:280:DyaK2c3itleqsg%3D%3D 8169692 10.1097/00005131-199402000-00008
    • Moed BR, Karges DE. Prophylactic indomethacin for the prevention of heterotopic ossification after acetabular fracture surgery in high-risk patients. J Orthop Trauma. 1994;8:34-39.
    • (1994) J Orthop Trauma. , vol.8 , pp. 34-39
    • Moed, B.R.1    Karges, D.E.2
  • 35
    • 0027354523 scopus 로고
    • Functional outcome following surgical excision of heterotopic ossification in patients with traumatic brain injury
    • 1:STN:280:DyaK3s7mtl2ntQ%3D%3D 8433193 10.1097/00005131-199302000-00003
    • Moore TJ. Functional outcome following surgical excision of heterotopic ossification in patients with traumatic brain injury. J Orthop Trauma. 1993;7:11-14.
    • (1993) J Orthop Trauma. , vol.7 , pp. 11-14
    • Moore, T.J.1
  • 36
    • 0142147985 scopus 로고    scopus 로고
    • Temporal and spatial expression profiles of bmp receptors and noggin during BMP-2-induced ectopic bone formation
    • 1:CAS:528:DC%2BD3sXosFynsrY%3D 14584896 10.1359/jbmr.2003.18.10.1854
    • Nakamura Y, Wakitani S, Nakayama J, Wakabayashi S, Horiuchi H, Takaoka K. Temporal and spatial expression profiles of bmp receptors and noggin during BMP-2-induced ectopic bone formation. J Bone Miner Res. 2003;18:1854-1862.
    • (2003) J Bone Miner Res. , vol.18 , pp. 1854-1862
    • Nakamura, Y.1    Wakitani, S.2    Nakayama, J.3    Wakabayashi, S.4    Horiuchi, H.5    Takaoka, K.6
  • 39
    • 33847634913 scopus 로고    scopus 로고
    • Heterotopic ossification following traumatic and combat-related amputations. Prevalence, risk factors, and preliminary results of excision
    • 17332095 10.2106/JBJS.F.00412
    • Potter BK, Burns TC, Lacap AP, Granville RR, Gajewski DA. Heterotopic ossification following traumatic and combat-related amputations. Prevalence, risk factors, and preliminary results of excision. J Bone Joint Surg Am. 2007;89:476-486.
    • (2007) J Bone Joint Surg Am. , vol.89 , pp. 476-486
    • Potter, B.K.1    Burns, T.C.2    Lacap, A.P.3    Granville, R.R.4    Gajewski, D.A.5
  • 40
    • 0029004190 scopus 로고
    • Biosynthesis and characterization of type x olalgen in human fetal epiphyseal growth plate cartilage
    • 1:STN:280:DyaK28%2FhtVCmtg%3D%3D 7584316 10.1016/S1063-4584(05)80043-3
    • Reginato AM, Sanz-Rodriguez C, Jimenez SA. Biosynthesis and characterization of type x olalgen in human fetal epiphyseal growth plate cartilage. Osteoarthritis Cartilage. 1995;3:105-116.
    • (1995) Osteoarthritis Cartilage. , vol.3 , pp. 105-116
    • Reginato, A.M.1    Sanz-Rodriguez, C.2    Jimenez, S.A.3
  • 41
    • 0024780923 scopus 로고
    • Monokines produced by macrophages stimulate the growth of osteoblasts
    • 1:STN:280:DyaK3c3gtVCjsA%3D%3D 2630169 10.3109/03008208909002416
    • Rifas L, Cheng SL, Shen V, Peck WA. Monokines produced by macrophages stimulate the growth of osteoblasts. Connect Tissue Res. 1989;23:163-178.
    • (1989) Connect Tissue Res. , vol.23 , pp. 163-178
    • Rifas, L.1    Cheng, S.L.2    Shen, V.3    Peck, W.A.4
  • 42
    • 52949105668 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 (BMP-2) and vascular endotheslial growth factor (VEGF) transfection to human periosteal cells enhances osteoblastic differentiation and bone formation
    • 1:CAS:528:DC%2BD1cXht1amtr%2FM 18776714 10.1254/jphs.08036FP
    • Samee M, Kasugai S, Kondo H, Ohya K, Shimokawa H, Kuroda S. Bone morphogenetic protein-2 (BMP-2) and vascular endotheslial growth factor (VEGF) transfection to human periosteal cells enhances osteoblastic differentiation and bone formation. J Pharmacol Sci. 2008;108:18-31.
    • (2008) J Pharmacol Sci. , vol.108 , pp. 18-31
    • Samee, M.1    Kasugai, S.2    Kondo, H.3    Ohya, K.4    Shimokawa, H.5    Kuroda, S.6
  • 43
    • 0024247039 scopus 로고
    • Localization of the expression of types I, III, and IV collagen, TGF-beta 1 and c-FOS genes in developing human calvarial bones
    • 1:CAS:528:DyaL1MXlt1Sh 3053296 10.1016/0012-1606(88)90438-1
    • Sandberg M, Autio-Harmainen H, Vuorio E. Localization of the expression of types I, III, and IV collagen, TGF-beta 1 and c-FOS genes in developing human calvarial bones. Dev Biol. 1988;130:324-334.
    • (1988) Dev Biol. , vol.130 , pp. 324-334
    • Sandberg, M.1    Autio-Harmainen, H.2    Vuorio, E.3
  • 44
    • 0025952992 scopus 로고
    • Heterotopic ossification: Clinical and celluar aspects
    • 1:STN:280:DyaK38%2FjsVegug%3D%3D 1933586 10.1007/BF02556120
    • Sawyer JR, Myers MA, Rosier RN, Puzas JE. Heterotopic ossification: clinical and celluar aspects. Calcif Tissue Int. 1991;49:208-215.
    • (1991) Calcif Tissue Int. , vol.49 , pp. 208-215
    • Sawyer, J.R.1    Myers, M.A.2    Rosier, R.N.3    Puzas, J.E.4
  • 46
    • 0029746491 scopus 로고    scopus 로고
    • Overexpression of an osteogenic morphogen in fibrodysplasia ossificans progressiva
    • 1:CAS:528:DyaK28Xlslymtro%3D 8678932 10.1056/NEJM199608223350804
    • Shafritz AB, Shore EM, Gannon FH, Zasloff MA, Taub R, Muenke M, Kaplan FS. Overexpression of an osteogenic morphogen in fibrodysplasia ossificans progressiva. N Engl J Med. 1996;335:555-561.
    • (1996) N Engl J Med. , vol.335 , pp. 555-561
    • Shafritz, A.B.1    Shore, E.M.2    Gannon, F.H.3    Zasloff, M.A.4    Taub, R.5    Muenke, M.6    Kaplan, F.S.7
  • 47
    • 0033532057 scopus 로고    scopus 로고
    • SMAD1 interacts with homeobox DNA-binding proteins in bone morphogenetic protein signaling
    • 1:CAS:528:DyaK1MXjtFOrsbk%3D 10224145 10.1074/jbc.274.19.13711
    • Shi X, Yang X, Chen D, Chang Z, Cao X. SMAD1 interacts with homeobox DNA-binding proteins in bone morphogenetic protein signaling. J Biol Chem. 1999;274:13711-13717.
    • (1999) J Biol Chem. , vol.274 , pp. 13711-13717
    • Shi, X.1    Yang, X.2    Chen, D.3    Chang, Z.4    Cao, X.5
  • 48
    • 0034100664 scopus 로고    scopus 로고
    • Osteogenic induction in hereditary disorders of heterotopic ossification
    • 10818990 10.1097/00003086-200005000-00028
    • Shore EM, Glaser DL, Gannon FH. Osteogenic induction in hereditary disorders of heterotopic ossification. Clin Orthop Relat Res. 2000;374:303-316.
    • (2000) Clin Orthop Relat Res. , vol.374 , pp. 303-316
    • Shore, E.M.1    Glaser, D.L.2    Gannon, F.H.3
  • 49
    • 34748873143 scopus 로고    scopus 로고
    • Symptomatic heterotopic ossification after very severe traumatic brain injury in 114 patients: Incidence and risk factors
    • 17572418 10.1016/j.injury.2007.03.019
    • Simonsen LL, Sonne-Holm S, Krasheninnikoff M, Engberg AW. Symptomatic heterotopic ossification after very severe traumatic brain injury in 114 patients: incidence and risk factors. Injury. 2007;38:1146-1150.
    • (2007) Injury. , vol.38 , pp. 1146-1150
    • Simonsen, L.L.1    Sonne-Holm, S.2    Krasheninnikoff, M.3    Engberg, A.W.4
  • 50
    • 68049138991 scopus 로고    scopus 로고
    • The role of hypoxia-inducible factor in osteogenesis and chondrogenesis
    • 1:CAS:528:DC%2BD1MXlt1Kmt7s%3D 19308769 10.1080/14653240902824765
    • Sun X, Wei Y. The role of hypoxia-inducible factor in osteogenesis and chondrogenesis. Cytotherapy. 2009;11:261-267.
    • (2009) Cytotherapy. , vol.11 , pp. 261-267
    • Sun, X.1    Wei, Y.2
  • 51
    • 0033587653 scopus 로고    scopus 로고
    • Osteogenic protein-1 increases gene expression of vascualr endotheslial growth factor in primary cultures of fetal rat calvaria cells
    • 1:CAS:528:DyaK1MXjs1Sgs7Y%3D 10459859 10.1016/S0303-7207(99)00076-3
    • Yeh LC, Lee JC. Osteogenic protein-1 increases gene expression of vascualr endotheslial growth factor in primary cultures of fetal rat calvaria cells. Mol Cell Endocrinol. 1999;153:113-124.
    • (1999) Mol Cell Endocrinol. , vol.153 , pp. 113-124
    • Yeh, L.C.1    Lee, J.C.2
  • 52
    • 0036133515 scopus 로고    scopus 로고
    • Antiangiogenic treatment delays chondrocyte maturation and bone formation during limb skeletogenesis
    • 1:CAS:528:DC%2BD38XktFyitw%3D%3D 11771670 10.1359/jbmr.2002.17.1.56
    • Yin M, Gentili C, Koyama E, Zasloff MA, Pacifici M. Antiangiogenic treatment delays chondrocyte maturation and bone formation during limb skeletogenesis. J Bone Miner Res. 2002;17:56-65.
    • (2002) J Bone Miner Res. , vol.17 , pp. 56-65
    • Yin, M.1    Gentili, C.2    Koyama, E.3    Zasloff, M.A.4    Pacifici, M.5
  • 53
    • 70349124214 scopus 로고    scopus 로고
    • Sustained BMP signaling in osteoblasts stimulates bone formation by promoting angiogenesis and osteoblast differentiation
    • 1:CAS:528:DC%2BD1MXosFCkt78%3D 19257813 10.1359/jbmr.090204
    • Zhang F, Qiu T, Wu X, Wan C, Shi W, Wang YB, Chen J, Wan M, Clemens TL, Cao X. Sustained BMP signaling in osteoblasts stimulates bone formation by promoting angiogenesis and osteoblast differentiation. J Bone Miner Res. 2009;24:1224-1233.
    • (2009) J Bone Miner Res. , vol.24 , pp. 1224-1233
    • Zhang, F.1    Qiu, T.2    Wu, X.3    Wan, C.4    Shi, W.5    Wang, Y.B.6    Chen, J.7    Wan, M.8    Clemens, T.L.9    Cao, X.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.