TGF-ß induces Lysyl hydroxylase 2b in human synovial osteoarthritic fibroblasts through ALK5 signaling

Cell and Tissue Research

Volumn 355, Issue 1, 2014, Pages 163-171

  Remst, Dennis F G ^a   Blaney Davidson, Esmeralda N ^a   Vitters, Elly L ^a   Bank, Ruud A ^b   Van Den Berg, Wim B ^a   Van Der Kraan, Peter M ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Fibrosis; Lysyl hydroxylase 2b; Osteoarthritis; Synovium; TGF

Indexed keywords

2 OXOGLUTARATE 5 DIOXYGENASE 2; ACTIVIN RECEPTOR LIKE KINASE; ACTIVIN RECEPTOR LIKE KINASE 1; ACTIVIN RECEPTOR LIKE KINASE 2; ACTIVIN RECEPTOR LIKE KINASE 4; ACTIVIN RECEPTOR LIKE KINASE 7; BONE MORPHOGENETIC PROTEIN RECEPTOR 1A; BONE MORPHOGENETIC PROTEIN RECEPTOR 1B; CONNECTIVE TISSUE GROWTH FACTOR; DIOXYGENASE; LYSYL HYDROXYLASE 2B; PHOSPHOTRANSFERASE; PROCOLLAGEN; PROCOLLAGEN LYSINE 2 OXOGLUTARATE 5 DIOXYGENASE; SMAD PROTEIN; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD3P PROTEIN; SMAD5 PROTEIN; SMAD8P PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; UNCLASSIFIED DRUG;

ARTICLE; CELL STIMULATION; COL1A1 GENE; CONTROLLED STUDY; CTGF GENE; FIBROBLAST; FIBROSIS; GENE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; KNEE; LH2B GENE; OSTEOARTHRITIS; PLOD1 GENE; PLOD2 GENE; PLOD3 GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

MURINAE;

CELLS, CULTURED; CONNECTIVE TISSUE GROWTH FACTOR; FIBROBLASTS; FIBROSIS; GENE EXPRESSION REGULATION; HUMANS; OSTEOARTHRITIS; PROCOLLAGEN-LYSINE, 2-OXOGLUTARATE 5-DIOXYGENASE; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; SMAD1 PROTEIN; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 84893639707     PISSN: 0302766X     EISSN: 14320878     Source Type: Journal    
DOI: 10.1007/s00441-013-1740-5     Document Type: Article

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