Osteoarthritis-related fibrosis is associated with both elevated pyridinoline cross-link formation and lysyl hydroxylase 2b expression

Osteoarthritis and Cartilage

Volumn 21, Issue 1, 2013, Pages 157-164

  Remst, D F G ^a   Blaney Davidson, E N ^a   Vitters, E L ^a   Blom, A B ^a   Stoop, R ^b   Snabel, J M ^b   Bank, R A ^c   Van den Berg, W B ^a   Van der Kraan, P M ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b TNO   (Netherlands)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Fibrosis; Lysyl hydroxylase 2b; Osteoarthritis; Synovium; TGF

Indexed keywords

ADENOVIRUS VECTOR; CLOSTRIDIOPEPTIDASE A; COLLAGEN ALPHA1 CHAIN; COLLAGEN TYPE 1; CONNECTIVE TISSUE GROWTH FACTOR; MESSENGER RNA; PROCOLLAGEN LYSINE 2 OXOGLUTARATE 5 DIOXYGENASE; PROCOLLAGEN LYSINE 2 OXOGLUTARATE 5 DIOXYGENASE 2B; PYRIDINOLINE; TISSUE INHIBITOR OF METALLOPROTEINASE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CROSS LINKING; FIBROSIS; GENE EXPRESSION; GENETIC ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOLOGY; IMMUNOHISTOCHEMISTRY; KNEE OSTEOARTHRITIS; MALE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA ISOLATION;

AMINO ACIDS; ANIMALS; ARTHRITIS, EXPERIMENTAL; CHROMATOGRAPHY, LIQUID; COLLAGEN; CONNECTIVE TISSUE GROWTH FACTOR; EXTRACELLULAR MATRIX; FIBROSIS; GENE EXPRESSION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, INBRED C57BL; OSTEOARTHRITIS, KNEE; PROCOLLAGEN-LYSINE, 2-OXOGLUTARATE 5-DIOXYGENASE; RNA STABILITY; STIFLE; SYNOVIAL MEMBRANE; TRANSFORMING GROWTH FACTOR BETA;

EID: 84871924381     PISSN: 10634584     EISSN: 15229653     Source Type: Journal    
DOI: 10.1016/j.joca.2012.10.002     Document Type: Article

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