Magnetic resonance imaging predictors of treatment response in late-life depression

Journal of Geriatric Psychiatry and Neurology

Volumn 27, Issue 1, 2014, Pages 24-32

  Aizenstein, Howard J ^a,b   Khalaf, Alexander ^b   Walker, Sarah E ^b   Andreescu, Carmen ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

late life depression; MR imaging; neuroimaging

Indexed keywords

ARTICLE; BRAIN SIZE; CLINICAL DECISION MAKING; ELECTROCONVULSIVE THERAPY; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; HUMAN; LATE LIFE DEPRESSION; PREFRONTAL CORTEX; PRIORITY JOURNAL; TREATMENT OUTCOME; TREATMENT RESPONSE; WHITE MATTER;

LATE-LIFE DEPRESSION; MR IMAGING; NEUROIMAGING;

ADULT; AGE OF ONSET; AGED; AGED, 80 AND OVER; AGING; ANTIDEPRESSIVE AGENTS; DEPRESSION; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NERVE FIBERS, MYELINATED; PREDICTIVE VALUE OF TESTS; TREATMENT FAILURE; TREATMENT OUTCOME;

EID: 84893618807     PISSN: 08919887     EISSN: 15525708     Source Type: Journal    
DOI: 10.1177/0891988713516541     Document Type: Article

References (62)

1. Casten RJ, Rovner BW, Shmuely Dulitzki Y, Pasternak RE, Pelchat R, Ranen N. Predictors of recovery from major depression among geriatric psychiatry inpatients: the importance of caregivers' beliefs. Int Psychogeriatr. 1999 ; 11 (2). 149-157
2. Garcia Pena C, Wagner FA, Sanchez-Garcia S, et al. Late-life depressive symptoms: prediction models of change. J Affect Disord. 2013 ; 150 (3). 886-894
3. Hinrichsen GA, Hernandez NA. Factors associated with recovery from and relapse into major depressive disorder in the elderly. Am J Psychiatry. 1993 ; 150 (12). 1820-1825
4. Katon W, Unutzer J, Russo J. Major depression: the importance of clinical characteristics and treatment response to prognosis. Dep Anxiety. 2010 ; 27 (1). 19-26
5. Mulsant BH, Houck PR, Gildengers AG, et al. What is the optimal duration of a short-term antidepressant trial when treating geriatric depression?. J Clin Psychopharmacol. 2006 ; 26 (2). 113-120
6. Nelson JC, Delucchi KL, Schneider LS. Moderators of outcome in late-life depression: a patient-level meta-analysis. Am J Psychiatry. 2013 ; 170 (6). 651-659
7. Reynolds CF, Dew MA, Pollock BG, et al. Maintenance treatment of major depression in old age. N Engl J Med. 2006 ; 354 (11). 1130-1138
8. Andreescu C, Reynolds CF. Late-life depression: evidence-based treatment and promising new directions for research and clinical practice. Psychiatr Clin North Am. 2011 ; 34 (2). 335-355
9. Andreescu C, Lenze EJ, Mulsant BH, et al. High worry severity is associated with poorer acute and maintenance efficacy of antidepressants in late-life depression. Depress Anxiety. 2009 ; 26 (3). 266-272
10. Gunning FM, Cheng J, Murphy CF, et al. Anterior cingulate cortical volumes and treatment remission of geriatric depression. Int J Geriatr Psychiatry. 2009 ; 24 (8). 829-836
11. Gunning-Dixon FM, Walton M, Cheng J, et al. MRI signal hyperintensities and treatment remission of geriatric depression. J Affect Disord. 2010 ; 126 (3). 395-401
12. Hickie I, Scott E, Mitchell P, Wilhelm K, Austin MP, Bennett B. Subcortical hyperintensities on magnetic resonance imaging: clinical correlates and prognostic significance in patients with severe depression. Biol Psychiatry. 1995 ; 37 (3). 151-160
13. Shah PJ, Ebmeier KP, Glabus MF, Goodwin GM. Cortical grey matter reductions associated with treatment-resistant chronic unipolar depression. Controlled magnetic resonance imaging study. Br J Psychiatry. 1998 ; 172 (6). 527-532
14. Sheline YI, Barch DM, Donnelly JM, Ollinger JM, Snyder AZ, Mintun MA. Increased amygdala response to masked emotional faces in depressed subjects resolves with antidepressant treatment: an fMRI study. Biol Psychiatry. 2001 ; 50 (9). 651-658
15. Sheline YI, Pieper CF, Barch DM, et al. Support for the vascular depression hypothesis in late-life depression. Arch Gen Psychiatry. 2010 ; 67 (3). 277-286
16. Sneed JR, Culang-Reinlieb ME, Brickman AM, et al. MRI signal hyperintensities and failure to remit following antidepressant treatment. J Affect Disord. 2011 ; 135 (1-3). 315-320
17. Ownby RL. Evidence-based medicine and geriatric psychiatry. Curr Psychiatry Rep. 2004 ; 6 (1). 14-19
18. McGrath CL, Kelley ME, Holtzheimer PE, et al. Toward a neuroimaging treatment selection biomarker for major depressive disorder. JAMA Psychiatry. 2013 ; 70 (8). 821-829
19. Aizenstein HJ, Butters MA, Wu M, et al. Altered functioning of the executive control circuit in late-life depression: episodic and persistent phenomena. Am J Geriatr Psychiatry. 2009 ; 17 (1). 30-42
20. Alexopoulos GS, Hoptman MJ, Kanellopoulos D, Murphy CF, Lim KO, Gunning FM. Functional connectivity in the cognitive control network and the default mode network in late-life depression. J Affect Disord. 2012 ; 139 (1). 56-65
21. Alexopoulos GS, Kiosses DN, Choi SJ, Murphy CF, Lim KO. Frontal white matter microstructure and treatment response of late-life depression: a preliminary study. Am J Psychiatry. 2002 ; 159 (11). 1929-1932
22. Alexopoulos GS, Murphy CF, Gunning-Dixon FM, et al. Microstructural white matter abnormalities and remission of geriatric depression. Am J Psychiatry. 2008 ; 165 (2). 238-244
23. Andreescu C, Tudorascu DL, Butters MA, et al Psychiatry Res. 2013 :
24. Bella R, Pennisi G, Cantone M, et al. Clinical presentation and outcome of geriatric depression in subcortical ischemic vascular disease. Gerontology. 2010 ; 56 (3). 298-302
25. Brassen S, Kalisch R, Weber-Fahr W, Braus DF, Büchel C. Ventromedial prefrontal cortex processing during emotional evaluation in late-life depression: a longitudinal functional magnetic resonance imaging study. Biol Psychiatry. 2008 ; 64 (4). 349-355
26. Chen CH, Ridler K, Suckling J, et al. Brain imaging correlates of depressive symptom severity and predictors of symptom improvement after antidepressant treatment. Biol Psychiatry. 2007 ; 62 (5). 407-414
27. Franco AR, Holtzheimer PE, Kelley ME, Dunlop BW, Craighead WE, Mayberg HS.. Pretreatment resting state fMRI predicts differential response to CBT or medication. Biol Psychiatry. 2011 ; 69 (9). 165
28. Fu CH, Mourao-Miranda J, Costafreda SG, et al. Pattern classification of sad facial processing: toward the development of neurobiological markers in depression. Biol Psychiatry. 2008 ; 63 (7). 656-662
29. Fu CHY, Williams SCR, Brammer MJ, et al. Neural responses to happy facial experessions in major depression following antidepressant treatment. Am J Psychiatry. 2007 ; 164 (4). 599-607
30. Hsieh MH, McQuoid DR, Levy RM, Payne ME, MacFall JR, Steffens DC. Hippocampal volume and antidepressant response in geriatric depression. Int J Geriatr Psychiatry. 2002 ; 17 (6). 519-525
31. Janssen J, Hulshoff Pol HE, Schnack HG, et al. Cerebral volume measurements and subcortical white matter lesions and short-term treatment response in late life depression. Int J Geriatr Psychiatry. 2007 ; 22 (5). 468-474
32. Langenecker SA, Kennedy SE, Guidotti LM, et al. Frontal and limbic activation during inhibitory control predicts treatment response in major depressive disorder. Biol Psychiatry. 2007 ; 62 (11). 1272-1280
33. Lemogne C, Mayberg H, Bergouignan L, et al. Self-referential processing and the prefrontal cortex over the course of depression: a pilot study. J Affect Disord. 2010 ; 124 (1-2). 196-201
34. Lisiecka D, Meisenzahl E, Scheuerecker J, et al. Neural correlates of treatment outcome in major depression. Int J Neuropsychopharmacol. 2011 ; 14 (4). 521-534
35. Lui S, Wu Q, Qiu L, et al. Resting-state functional connectivity in treatment-resistant depression. Am J Psychiatry. 2011 ; 168 (6). 642-648
36. Salloway S, Correia S, Boyle P, et al. MRI subcortical hyperintensities in old and very old depressed outpatients: the important role of age in late-life depression. J Neurol Sci. 2002 ; 203-204: 227-233
37. Simpson S, Baldwin RC, Jackson A, Burns S. Is subcortical disease associated with a poor response to antidepressants? neurological, neuropsychological and neuroradiological findings in late-life depression. Psychological Med. 1998 ; 28 (5). 1015-1026
38. Taylor WD, Kuchibhatla M, Payne ME, et al. Frontal white matter anisotropy and antidepressant remission in late-life depression. PLoS One. 2008 ; 3 (9). e3267
39. Wang L, Krishnan KR, Steffens DC, Potter GG, Dolcos F, McCarthy G. Depressive state- and disease-related alterations in neural responses to affective and executive challenges in geriatric depression. Am J Psychiatry. 2008 ; 165 (7). 863-871
40. Gildengers AG, Houck PR, Mulsant BH, et al. Trajectories of treatment response in late-life depression: psychosocial and clinical correlates. J Clin Psychopharmacol. 2005 ; 25 (4 suppl 1). S8 - S13
41. Harmer CJ, Goodwin GM, Cowen PJ. Why do antidepressants take so long to work? a cognitive neuropsychological model of antidepressant drug action. Br J Psychiatry. 2009 ; 195 (2). 102-108
42. Bigos KL, Pollock BG, Aizenstein HJ, Fisher PM, Bies RR, Hariri AR. Acute 5-HT reuptake blockade potentiates human amygdala reactivity. Neuropsychopharmacology. 2008 ; 33 (13). 3221-3225
43. Rawlings NB, Norbury R, Cowen PJ, Harmer CJ. A single dose of mirtazapine modulates neural responses to emotional faces in healthy people. Psychopharmacology (Berl). 2010 ; 212 (4). 625-634
44. Botteron KC, Carter C, Castellanos FX, et al Consensus Report of the APA Work Group on Neuroimaging Markers of Psychiatric Disorders. Arlington, VA: American Psychiatric Association ; 2012 :
45. Gelenberg AJ, Freeman MP, Markowitz JC, et al Practice Guideline for the treatment of patients with Major Depressive Disorder. Arlington, VA: American Psychiatric Association ; 2010 :
46. Knopman DS, DeKosky ST, Cummings JL, et al. Practice parameter: diagnosis of dementia (an evidence-based review): report of the quality standards subcommittee of the american academy of neurology. Neurology. 2001 ; 56 (9). 1143-1153
47. Rabins PV, Blacker D, Rovner BW, et al. Practice guideline for the treatment of patients with alzheimer's disease and other dementias. Am J Psychiatry. 2007 ; 164 (12). 5-56
48. Albert MS, DeKosky ST, Dickson D, et al. The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the national institute on aging-alzheimer's association workgroups on diagnostic guidelines for alzheimer's disease. Alzheimers Dement. 2011 ; 7 (3). 270-279
49. Jack CR, Albert MS, Knopman DS, et al. Introduction to the recommendations from the national institute on aging-Alzheimer's association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement. 2011 ; 7 (3). 257-262
50. McKhann GM, Knopman DS, Chertkow H, et al. The diagnosis of dementia due to Alzheimer's disease: recommendations from the national institute on aging-Alzheimer's association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement. 2011 ; 7 (3). 263-269
51. Sperling RA, Aisen PS, Beckett LA, et al. Toward defining the preclinical stages of Alzheimer's disease: recommendations from the national institute on aging-Alzheimer's association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement. 2011 ; 7 (3). 280-292
52. Johnson KA, Minoshima S, Bohnen NI, et al. Appropriate use criteria for amyloid PET: a report of the amyloid imaging task force, the society of nuclear medicine and molecular imaging, and the Alzheimer's association. Alzheimers Dement. 2013 ; 9 (1). e-1-16
53. Sexton CE, Allan CL, Masurier ML, et al. Magnetic resonance imaging in late-life depression. Arch Gen Psychiatry. 2013 ; 69 (7). 680-689
54. Vu NQ, Aizenstein HJ. Depression in the elderly: brain correlates, neuropsychological findings, and role of vascular lesion load. Curr Opin Neurol. 2013 ; 26 (6). 656-661
55. Alexopoulos GS, Meyers BS, Young RC, Kakuma T, Silbersweig D, Charlson M. Clinically defined vascular depression. Am J Psychiatry. 1997 ; 154 (4). 562-565
56. Taylor WD, Aizenstein HJ, Alexopoulos GS. The vascular depression hypothesis: mechanisms linking vascular disease with depression. Mol psychiatry. 2013 ; 18 (9). 963-974
57. Hopkins RO, Beck CJ, Burnett DL, Weaver LK, Victoroff J, Bigler ED. Prevalence of white matter hyperintensities in a young healthy population. J Neuroimaging. 2006 ; 16 (3). 243-251
58. Price JL, Drevets WC. Neural circuits underlying the pathophysiology of mood disorders. Trends Cogn Sci. 2012 ; 16 (1). 61-71
59. Mayberg HS. Defining the neural circuitry of depression: Toward a new nosology with therapeutic implications. Biol Psychiatry. 2007 ; 61 (6). 729-730
60. Phillips ML, Drevets WC, Rauch SL, Lane R. Neurobiology of emotion perception II: implications for major psychiatric disorders. Biol Psychiatry. 2003 ; 54 (5). 515-528
61. Aizenstein HJ, Andreescu C. Edelman KL, et al. fMRI correlates of white matter hyperintensities in late-life depression. Am J Psychiatry. 2011 ; 168 (10). 1075-1082
62. Steffens DC, Taylor WD, Krishnan KRR. Progression of subcortical ischemic disease from vascular depression to vascular dementia. Am J Psychiatry. 2003 ; 160 (10). 1751-1756