Neural correlates of treatment outcome in major depression

International Journal of Neuropsychopharmacology

Volumn 14, Issue 4, 2011, Pages 521-534

  Lisiecka, Danuta ^a   Meisenzahl, Eva ^b   Scheuerecker, Johanna ^b   Schoepf, Veronica ^c   Whitty, Peter ^a   Chaney, Aisling ^a   Moeller, Hans Juergen ^b   Wiesmann, Martin ^c   Frodl, Thomas ^a,b  

^a ADELAIDE AND MEATH HOSPITAL   (Ireland)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

Antidepressant medications; biomarkers; fMRI; functional connectivity; major depression; treatment response

Indexed keywords

MIRTAZAPINE; VENLAFAXINE;

ANGULAR GYRUS; ARTICLE; CAUDATE NUCLEUS; CEREBELLUM; CINGULATE GYRUS; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; MAJOR DEPRESSION; MALE; MOTOR CORTEX; NERVE CELL; ORBITAL CORTEX; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TASK PERFORMANCE; THALAMUS; TREATMENT OUTCOME; TREATMENT RESPONSE;

ADULT; AFFECT; ANTIDEPRESSIVE AGENTS; BIOLOGICAL MARKERS; CEREBRAL CORTEX; CYCLOHEXANOLS; DEPRESSIVE DISORDER, MAJOR; FACE; FEMALE; FRONTAL LOBE; HUMANS; MALE; MIANSERIN; MIDDLE AGED; NERVE NET; PSYCHIATRIC STATUS RATING SCALES; TREATMENT OUTCOME; YOUNG ADULT;

EID: 79960279021     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S1461145710001513     Document Type: Article

References (78)

1. Alexopoulos G, Murphy C, Gunning-Dixon F, Kalayam B, et al. (2007). Event-related potentials in an emotional go/no-go task and remission of geriatric depression. Neuroreport 18, 217-221.
2. Anand A, Li Y, Wang Y, Wu J, et al. (2005). Antidepressant effect on connectivity of the mood-regulating circuit : an FMRI study. Neuropsychopharmacology 30, 1334-1344. (Pubitemid 40848087)
3. Anand A, Li Y, Wang Y, Gardner K, et al. (2007). Reciprocal effects of antidepressant treatment on activity and connectivity of the mood regulating circuit : an FMRI study. Journal of Neuropsychiatry and Clinical Neurosciences 19, 274-282. (Pubitemid 47293900)
4. Andreescu C, Butters M, Lenze E, Venkatraman V, et al. (2009). fMRI activation in late-life anxious depression: a potential biomarker. International Journal of Geriatric Psychiatry 24, 820-828.
5. Benjamini Y, Hochberg Y (1995). Controlling the false discovery rate - a practical and powerful approach to multiple testing. Journal of the Royal Statistical Society Series B (Statistical Methodology) 57, 289-300.
6. Biver F, Goldman S, Delvenne V, Luxen A, et al. (1994). Frontal and parietal metabolic disturbances in unipolar depression. Biological Psychiatry 36, 381-388. (Pubitemid 24305945)
7. Biver F, Wikler D, Lotstra F, Damhaut P, et al. (1997). Serotonin 5-HT2 receptor imaging in major depression: focal changes in orbito-insular cortex. British Journal of Psychiatry 171, 444-448. (Pubitemid 27475842)
8. Blackburn I, Bishop S, Glen A, Whalley L, et al. (1981). The efficacy of cognitive therapy in depression: a treatment trial using cognitive therapy and pharmacotherapy, each alone and in combination. British Journal of Psychiatry 139, 181-189. (Pubitemid 11044088)
9. Bokde A, Lopez-Bayo P, Meindl T, Pechler S, et al. (2006). Functional connectivity of the fusiform gyrus during a face-matching task in subjects with mild cognitive impairment. Brain 129, 1113-1124.
10. Bremner J (2002). Structural changes in the brain in depression and relationship to symptom recurrence. CNS Spectrums 7, 129-130, 135-129.
11. Caetano S, Hatch J, Brambilla P, Sassi R, et al. (2004). Anatomical MRI study of hippocampus and amygdala in patients with current and remitted major depression. Psychiatry Research 132, 141-147. (Pubitemid 39643011)
12. Canli T, Cooney R, Goldin P, Shah M, et al. (2005). Amygdala reactivity to emotional faces predicts improvement in major depression. Neuroreport 16, 1267-1270. (Pubitemid 41225193)
13. Chen C, Suckling J, Ooi C, Fu C, et al. (2008). Functional coupling of the amygdala in depressed patients treated with antidepressant medication. Neuropsychopharmacology 33, 1909-1918. (Pubitemid 351832606)
14. Christensen M, Lundbye-Jensen J, Petersen N, Geertsen S, et al. (2007). Watching your foot move - an fMRI study of visuomotor interactions during foot movement. Cerebral Cortex 17, 1906-1917. (Pubitemid 47216509)
15. Damasio A (1996). The somatic marker hypothesis and the possible functions of the prefrontal cortex. Philosophical Transactions of the Royal Society of London, Series B: Biological Sciences 351, 1413-1420. (Pubitemid 127738807)
16. Davidson R, Irwin W, Anderle M, Kalin N (2003). The neural substrates of affective processing in depressed patients treated with venlafaxine. American Journal of Psychiatry 160, 64-75. (Pubitemid 36042428)
17. Davidson R, Pizzagalli D, Nitschke J, Putnam K (2002). Depression: perspectives from affective neuroscience. Annual Review of Psychology 53, 545-574.
18. Dichter G, Felder J, Petty C, Bizzell J, et al. (2009). The effects of psychotherapy on neural responses to rewards in major depression. Biological Psychiatry 66, 886-897.
19. Drevets W (1998). Functional neuroimaging studies of depression: the anatomy of melancholia. Annual Review of Medicine 49, 341-361. (Pubitemid 28197459)
20. Drevets W (2001). Neuroimaging and neuropathological studies of depression: implications for the cognitiveemotional features of mood disorders. Current Opinion in Neurobiology 11, 240-249. (Pubitemid 32289413)
21. Drevets W(2007). Orbitofrontal cortex function and structure in depression. Annals of the New York Academy of Sciences 1121, 499-527.
22. Drevets W, Price J, Simpson JJ, Todd R, et al. (1997). Subgenual prefrontal cortex abnormalities in mood disorders. Nature 386, 824-827. (Pubitemid 27181254)
23. Drevets W, Raichle M (1992). Neuroanatomical circuits in depression: implications for treatment mechanisms. Psychopharmacology Bulletin 28, 261-274.
24. Drevets W, Savitz J, Trimble M (2008). The subgenual anterior cingulate cortex in mood disorders. CNS Spectrums 13, 663-681.
25. Elliott R, Sahakian B, Matthews K, Bannerjea A, et al. (1997). Effects of methylphenidate on spatial working memory and planning in healthy young adults. Psychopharmacology (Berlin) 131, 196-206. (Pubitemid 27261609)
26. Epstein J, Pan H, Kocsis J, Yang Y, et al. (2006). Lack of ventral striatal response to positive stimuli in depressed vs. normal subjects. American Journal of Psychiatry 163, 1784-1790. (Pubitemid 44522488)
27. Fitzgerald P, Laird A, Maller J, Daskalakis Z (2008). A metaanalytic study of changes in brain activation in depression. Human Brain Mapping 29, 683-695. (Pubitemid 351794123)
28. Friston K, Tononi G, Reeke GJ, Sporns O, et al. (1994). Value-dependent selection in the brain : simulation in a synthetic neural model. Neuroscience 59, 229-243. (Pubitemid 24098785)
29. Frodl T, Bokde A, Scheuerecker J, Lisiecka D, et al. (2010). Functional connectivity bias of the orbitofrontal cortex in drug-free patients with major depression. Biological Psychiatry 67, 161-167.
30. Frodl T, Scheuerecker J, Albrecht J, Kleemann A, et al. (2009). Neuronal correlates of emotional processing in patients with major depression. World Journal of Biological Psychiatry 10, 202-208.
31. Fu C, Williams S, Brammer M, Suckling J, et al. (2007). Neural responses to happy facial expressions in major depression following antidepressant treatment. American Journal of Psychiatry 164, 599-607. (Pubitemid 46650191)
32. Fu C, Williams S, Cleare A, Brammer M, et al. (2004). Attenuation of the neural response to sad faces in major depression by antidepressant treatment: a prospective, event-related functional magnetic resonance imaging study. Archives of General Psychiatry 61, 877-889. (Pubitemid 39181077)
33. Greicius M, Flores B, Menon V, Glover G, et al. (2007). Resting-state functional connectivity in major depression: abnormally increased contributions from subgenual cingulate cortex and thalamus. Biological Psychiatry 62, 429-437. (Pubitemid 47284017)
34. Grimm S, Beck J, Schuepbach D, Hell D, et al. (2008). Imbalance between left and right dorsolateral prefrontal cortex in major depression is linked to negative emotional judgment: an fMRI study in severe major depressive disorder. Biological Psychiatry 63, 369-376.
35. Gur R, McGrath C, Chan R, Schroeder L, et al. (2002). An fMRI study of facial emotion processing in patients with schizophrenia. American Journal of Psychiatry 159, 1992-1999. (Pubitemid 35423857)
36. Hariri A, Tessitore A, Mattay V, Fera F, et al. (2002). The amygdala response to emotional stimuli : a comparison of faces and scenes. Neuroimage 17, 317-323.
37. Indovina I, Sanes J (2001). Combined visual attention and finger movement effects on human brain representations. Experimental Brain Research 140, 265-279. (Pubitemid 32835331)
38. Keedwell P, Andrew C, Williams S, Brammer M, et al. (2005). A double dissociation of ventromedial prefrontal cortical responses to sad and happy stimuli in depressed and healthy individuals. Biological Psychiatry 58, 495-503. (Pubitemid 41393612)
39. Kim J, Horwitz B (2008). Investigating the neural basis for fMRI-based functional connectivity in a blocked design: application to interregional correlations and psychophysiological interactions. Magnetic Resonance Imaging 26, 583-593.
40. Konarski J, Kennedy S, Segal Z, Lau M, et al. (2009). Predictors of nonresponse to cognitive behavioural therapy or venlafaxine using glucose metabolism in major depressive disorder. Journal of Psychiatry and Neuroscience 34, 175-180.
41. Kringelbach M, Rolls E (2004). The functional neuroanatomy of the human orbitofrontal cortex : evidence from neuroimaging and neuropsychology. Progress in Neurobiology 72, 341-372. (Pubitemid 38626161)
42. Lemogne C, le Bastard G, Mayberg H, Volle E, et al. (2009). In search of the depressive self : extended medial prefrontal network during self-referential processing in major depression. Social Cognitive and Affective Neuroscience 4, 305-312.
43. Lotrich F, Pollock B (2005). Aging and clinical pharmacology: implications for antidepressants. Journal of Clinical Pharmacology 45, 1106-1122. (Pubitemid 41361911)
44. Manji H, Drevets W, Charney D (2001). The cellular neurobiology of depression. Nature Medicine 7, 541-547. (Pubitemid 32448319)
45. Mayberg H (1997). Limbic-cortical dysregulation: a proposed model of depression. Journal of Neuropsychiatry and Clinical Neuroscience 9, 471-481. (Pubitemid 27363950)
46. Mayberg H (2003). Modulating dysfunctional limbic-cortical circuits in depression: towards development of brainbased algorithms for diagnosis and optimised treatment. British Medical Bulletin 65, 193-207. (Pubitemid 36406467)
47. Mayberg H (2007). Defining the neural circuitry of depression: toward a new nosology with therapeutic implications. Biological Psychiatry 61, 729-730. (Pubitemid 46343724)
48. McGrady A, Yonker R, Tan S, Fine T, et al. (1981). The effect of biofeedback-assisted relaxation training on blood pressure and selected biochemical parameters in patients with essential hypertension. Biofeedback and Self Regulation 6, 343-353.
49. Meyer-Lindenberg A, Mervis C, Sarpal D, Koch P, et al. (2005). Functional, structural, and metabolic abnormalities of the hippocampal formation in Williams syndrome. Journal of Clinical Investigations 115, 1888-1895. (Pubitemid 40979728)
50. Mills N, Delbello M, Adler C, Strakowski S (2005). MRI analysis of cerebellar vermal abnormalities in bipolar disorder. American Journal of Psychiatry 162, 1530-1532. (Pubitemid 41105570)
51. Mitterschiffthaler M, Kumari V, Malhi G, Brown R, et al. (2003). Neural response to pleasant stimuli in anhedonia: an fMRI study. Neuroreport 14, 177-182. (Pubitemid 36308405)
52. Nestler E, Barrot M, DiLeone R, Eisch A, et al. (2002a). Neurobiology of depression. Neuron 34, 13-25. (Pubitemid 34270695)
53. Nestler E, Gould E, Manji H, Buncan M, et al. (2002b). Preclinical models: status of basic research in depression. Biological Psychiatry 52, 503-528. (Pubitemid 35284020)
54. Nitschke M, Kleinschmidt A, Wessel K, Frahm J (1996). Somatotopic motor representation in the human anterior cerebellum. A high-resolution functional MRI study. Brain 119, 1023-1029.
55. Peng J, Liu J, Nie B, Li Y, et al. (in press). Cerebral and cerebellar gray matter reduction in first-episode patients with major depressive disorder : a voxel-based morphometry study. European Journal of Radiology.
56. Pesso A (2004). Memory and consciousness: in the minds eye, in the minds body. Psychoterapie 9, 260-266.
57. Rajkowska G (2000). Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells. Biological Psychiatry 48, 766-777.
58. Ramnani N, Behrens T, Penny W, Matthews P (2004). New approaches for exploring anatomical and functional connectivity in the human brain. Biological Psychiatry 56, 613-619. (Pubitemid 39446841)
59. Ramnani N, Miall R (2003). Instructed delay activity in the human prefrontal cortex is modulated by monetary reward expectation. Cerebral Cortex 13, 318-327. (Pubitemid 36236678)
60. Robertson B, Wang L, Diaz M, Aiello M, et al. (2007). Effect of bupropion extended release on negative emotion processing in major depressive disorder : a pilot functional magnetic resonance imaging study. Journal of Clinical Psychiatry 68, 261-267. (Pubitemid 46362648)
61. Rogers M, Kasai K, Koji M, Fukuda R, et al. (2004). Executive and prefrontal dysfunction in unipolar depression: a review of neuropsychological and imaging evidence. Neuroscience Research 50, 1-11. (Pubitemid 39024296)
62. Salvadore G, Cornwell B, Colon-Rosario V, Coppola R, et al. (2009). Increased anterior cingulate cortical activity in response to fearful faces : a neurophysiological biomarker that predicts rapid antidepressant response to ketamine. Biological Psychiatry 65, 289-295.
63. Schaefer H, Putnam K, Benca R, Davidson R (2006). Event-related functional magnetic resonance imaging measures of neural activity to positive social stimuli in pre- and post-treatment depression. Biological Psychiatry 60, 974-986. (Pubitemid 44584208)
64. Schmahmann J (2000). The role of the cerebellum in affect and psychosis. Journal of Neurolinguistics 13, 189-214.
65. Schmahmann J (2004). Disorders of the cerebellum: ataxia, dysmetria of thought, and the cerebellar cognitive affective syndrome. Journal of Neuropsychiatry and Clinical Neuroscience 16, 367-378. (Pubitemid 39244566)
66. Seminowicz D, Mayberg H, McIntosh A, Goldapple K, et al. (2004). Limbic-frontal circuitry in major depression: a path modeling metanalysis. Neuroimage 22, 409-418. (Pubitemid 38515850)
67. Sheline Y, Barch D, Donnelly J, Ollinger J, et al. (2001). Increased amygdala response to masked emotional faces in depressed subjects resolves with antidepressant treatment: an fMRI study. Biological Psychiatry 50, 651-658. (Pubitemid 33043767)
68. Sheline Y, Mittler B, Mintun M (2002). The hippocampus and depression. European Psychiatry 17 (Suppl. 3), 300-305. (Pubitemid 34839392)
69. Sheline Y, Price J, Yan Z, Mintun M (2010). Resting-state functional MRI in depression unmasks increased connectivity between networks via the dorsal nexus. Proceedings of the National Academy of Sciences USA 107, 11020-11025.
70. Siegfried K, OConnolly M (1986). Cognitive and psychomotor effects of different antidepressants in the treatment of old age depression. International Clinical Psychopharmacology 1, 231-243.
71. Steele J, Meyer M, Ebmeier K (2004). Neural predictive error signal correlates with depressive illness severity in a game paradigm. Neuroimage 23, 269-280. (Pubitemid 39119457)
72. Sullivan P, Neale M, Kendler K (2000). Genetic epidemiology of major depression: review and metaanalysis. American Journal of Psychiatry 157, 1552-1562.
73. Townsend J, Eberhart N, Bookheimer S, Eisenberger N, et al. (2010). fMRI activation in the amygdala and the orbitofrontal cortex in unmedicated subjects with major depressive disorder. Psychiatry Research 183, 209-217.
74. Tremblay L, Naranjo C, Graham S, Herrmann N, et al. (2005). Functional neuroanatomical substrates of altered reward processing in major depressive disorder revealed by a dopaminergic probe. Archives of General Psychiatry 62, 1228-1236. (Pubitemid 41586922)
75. Wagner G, Sinsel E, Sobanski T, Kohler S, et al. (2006). Cortical inefficiency in patients with unipolar depression: an event-related FMRI study with the Stroop task. Biological Psychiatry 59, 958-965.
76. Wagner G, Koch K, Schachtzabel C, Reichenbach J, et al. (2008). Enhanced rostral anterior cingulate cortex activation during cognitive control is related to orbitofrontal volume reduction in unipolar depression. Journal of Psychiatry and Neuroscience 33, 199-208. (Pubitemid 351692419)
77. Wolf U, Rapoport M, Schweizer T (2009). Evaluating the affective component of the cerebellar cognitive affective syndrome. Journal of Neuropsychiatry and Clinical Neuroscience 21, 245-253.
78. Zhou Y, Yu C, Zheng H, Liu Y, et al. (2010). Increased neural resources recruitment in the intrinsic organization in major depression. Journal of Affective Disorders 121, 220-230.