A mechanistic investigation of the C-terminal redox motif of thioredoxin reductase from Plasmodium falciparum

Biochemistry

Volumn 53, Issue 3, 2014, Pages 601-609

  Snider, Gregg W ^a   Dustin, Christopher M ^a   Ruggles, Erik L ^a   Hondal, Robert J ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTROPHILIC ACTIVATION; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATES; PLASMODIUM FALCIPARUM; SITE DIRECTED MUTAGENESIS; SUBSTRATE RECOGNITION; TETRAPEPTIDE SEQUENCE; THIOL-DISULFIDE EXCHANGES; THIOREDOXIN REDUCTASE;

AMIDES; CATALYSIS; CATALYST ACTIVITY; COVALENT BONDS; ENZYME ACTIVITY; HYDROGEN BONDS; MOLECULAR MASS; PROTEINS; REDUCTION; SELENIUM COMPOUNDS; SUBSTRATES; SULFUR COMPOUNDS;

AMINO ACIDS;

CHIMERIC PROTEIN; SELENOCYSTEINE; THIOCTIC ACID; THIOREDOXIN; THIOREDOXIN REDUCTASE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BETA TURN; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CATALYST; CONTROLLED STUDY; ELECTRON TRANSPORT; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME STABILITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; HYDROGEN BOND; MOLECULAR RECOGNITION; MOLECULAR WEIGHT; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN SYNTHESIS; REDUCTION; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; CATALYSIS; CYSTINE; KINETICS; MODELS, CHEMICAL; NADP; ORGANOSELENIUM COMPOUNDS; OXIDATION-REDUCTION; PLASMODIUM FALCIPARUM; SELENOCYSTEINE; SUBSTRATE SPECIFICITY; THIOREDOXIN-DISULFIDE REDUCTASE;

EID: 84893499633     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi400931k     Document Type: Article

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