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Volumn 61, Issue , 2014, Pages 125-131

Microgravity control of autophagy modulates osteoclastogenesis

Author keywords

Autophagy; Microgravity; NASA; Osteoclast; Rotary cell culture system (RCCS)

Indexed keywords

AUTOPHAGY PROTEIN 5; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOKINE; GROWTH FACTOR; MEMBRANE PROTEIN; MESSENGER RNA; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN ATG16L; PROTEIN LC3; UNCLASSIFIED DRUG;

EID: 84893491250     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2014.01.004     Document Type: Article
Times cited : (82)

References (46)
  • 1
    • 0032896021 scopus 로고    scopus 로고
    • The effect of microgravity on morphology and gene expression of osteoblasts in vitro
    • Carmeliet G., Bouillon R. The effect of microgravity on morphology and gene expression of osteoblasts in vitro. FASEB J 1999, 13(Suppl.):S129-S134.
    • (1999) FASEB J , vol.13 , Issue.SUPPL.
    • Carmeliet, G.1    Bouillon, R.2
  • 2
    • 84879091707 scopus 로고    scopus 로고
    • Spaceflight-induced bone loss: is there an osteoporosis risk?
    • Sibonga J.D. Spaceflight-induced bone loss: is there an osteoporosis risk?. Curr Osteoporos Rep 2013, 11:92-98.
    • (2013) Curr Osteoporos Rep , vol.11 , pp. 92-98
    • Sibonga, J.D.1
  • 3
    • 0034043763 scopus 로고    scopus 로고
    • Bone loss during simulated weightlessness: a biomechanical and mineralization study in the rat model
    • Garber M.A., McDowell D.L., Hutton W.C. Bone loss during simulated weightlessness: a biomechanical and mineralization study in the rat model. Aviat Space Environ Med 2000, 71:586-592.
    • (2000) Aviat Space Environ Med , vol.71 , pp. 586-592
    • Garber, M.A.1    McDowell, D.L.2    Hutton, W.C.3
  • 4
    • 33746440607 scopus 로고    scopus 로고
    • Adaptation of the proximal femur to skeletal reloading after long-duration spaceflight
    • Lang T.F., Leblanc A.D., Evans H.J., Lu Y. Adaptation of the proximal femur to skeletal reloading after long-duration spaceflight. J Bone Miner Res 2006, 21:1224-1230.
    • (2006) J Bone Miner Res , vol.21 , pp. 1224-1230
    • Lang, T.F.1    Leblanc, A.D.2    Evans, H.J.3    Lu, Y.4
  • 5
    • 26944463908 scopus 로고    scopus 로고
    • Exercise and pharmacological countermeasures for bone loss during long-duration space flight
    • Cavanagh P.R., Licata A.A., Rice A.J. Exercise and pharmacological countermeasures for bone loss during long-duration space flight. Gravit Space Biol Bull 2005, 18:39-58.
    • (2005) Gravit Space Biol Bull , vol.18 , pp. 39-58
    • Cavanagh, P.R.1    Licata, A.A.2    Rice, A.J.3
  • 6
    • 13544261700 scopus 로고    scopus 로고
    • Regulatory mechanisms operative in osteoclasts
    • Reddy S.V. Regulatory mechanisms operative in osteoclasts. Crit Rev Eukaryot Gene Expr 2004, 14:255-270.
    • (2004) Crit Rev Eukaryot Gene Expr , vol.14 , pp. 255-270
    • Reddy, S.V.1
  • 7
    • 68849101656 scopus 로고    scopus 로고
    • Microgravity during spaceflight directly affects in vitro osteoclastogenesis and bone resorption
    • Tamma R., Colaianni G., Camerino C., Di Benedetto A., Greco G., Strippoli M., et al. Microgravity during spaceflight directly affects in vitro osteoclastogenesis and bone resorption. FASEB J 2009, 23:2549-2554.
    • (2009) FASEB J , vol.23 , pp. 2549-2554
    • Tamma, R.1    Colaianni, G.2    Camerino, C.3    Di Benedetto, A.4    Greco, G.5    Strippoli, M.6
  • 8
    • 0036203846 scopus 로고    scopus 로고
    • Vector-averaged gravity regulates gene expression of receptor activator of NF-kappaB (RANK) ligand and osteoprotegerin in bone marrow stromal cells via cyclic AMP/protein kinase A pathway
    • Kanematsu M., Yoshimura K., Takaoki M., Sato A. Vector-averaged gravity regulates gene expression of receptor activator of NF-kappaB (RANK) ligand and osteoprotegerin in bone marrow stromal cells via cyclic AMP/protein kinase A pathway. Bone 2002, 30:553-558.
    • (2002) Bone , vol.30 , pp. 553-558
    • Kanematsu, M.1    Yoshimura, K.2    Takaoki, M.3    Sato, A.4
  • 9
    • 0028954087 scopus 로고
    • Decreased mineralization and increased calcium release in isolated fetal mouse long bones under near weightlessness
    • Van Loon J.J., Bervoets D.J., Burger E.H., Dieudonne S.C., Hagen J.W., Semeins C.M., et al. Decreased mineralization and increased calcium release in isolated fetal mouse long bones under near weightlessness. J Bone Miner Res 1995, 10:550-557.
    • (1995) J Bone Miner Res , vol.10 , pp. 550-557
    • Van Loon, J.J.1    Bervoets, D.J.2    Burger, E.H.3    Dieudonne, S.C.4    Hagen, J.W.5    Semeins, C.M.6
  • 10
    • 0029929359 scopus 로고    scopus 로고
    • Effects of microgravity on osteoblast growth activation
    • Hughes-Fulford M., Lewis M.L. Effects of microgravity on osteoblast growth activation. Exp Cell Res 1996, 224:103-109.
    • (1996) Exp Cell Res , vol.224 , pp. 103-109
    • Hughes-Fulford, M.1    Lewis, M.L.2
  • 11
    • 0036194567 scopus 로고    scopus 로고
    • Characterization of the osteoblast-like cell phenotype under microgravity conditions in the NASA-approved Rotating Wall Vessel bioreactor (RWV)
    • Rucci N., Migliaccio S., Zani B.M., Taranta A., Teti A. Characterization of the osteoblast-like cell phenotype under microgravity conditions in the NASA-approved Rotating Wall Vessel bioreactor (RWV). J Cell Biochem 2002, 85:167-179.
    • (2002) J Cell Biochem , vol.85 , pp. 167-179
    • Rucci, N.1    Migliaccio, S.2    Zani, B.M.3    Taranta, A.4    Teti, A.5
  • 12
    • 0031914550 scopus 로고    scopus 로고
    • Bone formation and resorption biological markers in cosmonauts during and after a 180-day space flight (Euromir 95)
    • Caillot-Augusseau A., Lafage-Proust M.H., Soler C., Pernod J., Dubois F., Alexandre C. Bone formation and resorption biological markers in cosmonauts during and after a 180-day space flight (Euromir 95). Clin Chem 1998, 44:578-585.
    • (1998) Clin Chem , vol.44 , pp. 578-585
    • Caillot-Augusseau, A.1    Lafage-Proust, M.H.2    Soler, C.3    Pernod, J.4    Dubois, F.5    Alexandre, C.6
  • 13
    • 0032243373 scopus 로고    scopus 로고
    • Changes in the numbers of osteoclasts in newts under conditions of microgravity
    • Berezovska O.P., Rodionova N.V., Grigoryan E.N., Mitashov V.I. Changes in the numbers of osteoclasts in newts under conditions of microgravity. Adv Space Res 1998, 21:1059-1063.
    • (1998) Adv Space Res , vol.21 , pp. 1059-1063
    • Berezovska, O.P.1    Rodionova, N.V.2    Grigoryan, E.N.3    Mitashov, V.I.4
  • 14
    • 82455212740 scopus 로고    scopus 로고
    • Deterioration of bone quality in the tibia and fibula in growing mice during skeletal unloading: gender-related differences
    • Ko C.Y., Seo D.H., Kim H.S. Deterioration of bone quality in the tibia and fibula in growing mice during skeletal unloading: gender-related differences. J Biomech Eng 2011, 133:111003.
    • (2011) J Biomech Eng , vol.133 , pp. 111003
    • Ko, C.Y.1    Seo, D.H.2    Kim, H.S.3
  • 15
    • 84455191881 scopus 로고    scopus 로고
    • Pyruvate dehydrogenase kinase 4 induces bone loss at unloading by promoting osteoclastogenesis
    • Wang Y., Liu W., Masuyama R., Fukuyama R., Ito M., Zhang Q., et al. Pyruvate dehydrogenase kinase 4 induces bone loss at unloading by promoting osteoclastogenesis. Bone 2012, 50:409-419.
    • (2012) Bone , vol.50 , pp. 409-419
    • Wang, Y.1    Liu, W.2    Masuyama, R.3    Fukuyama, R.4    Ito, M.5    Zhang, Q.6
  • 18
    • 34848886914 scopus 로고    scopus 로고
    • Autophagosome formation: core machinery and adaptations
    • Xie Z., Klionsky D.J. Autophagosome formation: core machinery and adaptations. Nat Cell Biol 2007, 9:1102-1109.
    • (2007) Nat Cell Biol , vol.9 , pp. 1102-1109
    • Xie, Z.1    Klionsky, D.J.2
  • 19
    • 78650448754 scopus 로고    scopus 로고
    • Chemical modulators of autophagy as biological probes and potential therapeutics
    • Fleming A., Noda T., Yoshimori T., Rubinsztein D.C. Chemical modulators of autophagy as biological probes and potential therapeutics. Nat Chem Biol 2011, 7:9-17.
    • (2011) Nat Chem Biol , vol.7 , pp. 9-17
    • Fleming, A.1    Noda, T.2    Yoshimori, T.3    Rubinsztein, D.C.4
  • 20
    • 33750284176 scopus 로고    scopus 로고
    • Autophagy in cancer: good, bad, or both?
    • Hippert M.M., O'Toole P.S., Thorburn A. Autophagy in cancer: good, bad, or both?. Cancer Res 2006, 66:9349-9351.
    • (2006) Cancer Res , vol.66 , pp. 9349-9351
    • Hippert, M.M.1    O'Toole, P.S.2    Thorburn, A.3
  • 21
    • 83455173649 scopus 로고    scopus 로고
    • Autophagy proteins regulate the secretory component of osteoclastic bone resorption
    • DeSelm C.J., Miller B.C., Zou W., Beatty W.L., van Meel E., Takahata Y., et al. Autophagy proteins regulate the secretory component of osteoclastic bone resorption. Dev Cell 2011, 21:966-974.
    • (2011) Dev Cell , vol.21 , pp. 966-974
    • DeSelm, C.J.1    Miller, B.C.2    Zou, W.3    Beatty, W.L.4    van Meel, E.5    Takahata, Y.6
  • 22
    • 80755172329 scopus 로고    scopus 로고
    • Autophagic factors cut to the bone
    • Gelman A., Elazar Z. Autophagic factors cut to the bone. Dev Cell 2011, 21:808-810.
    • (2011) Dev Cell , vol.21 , pp. 808-810
    • Gelman, A.1    Elazar, Z.2
  • 23
    • 83455245194 scopus 로고    scopus 로고
    • Osteoclast precursor differentiation by MCPIP via oxidative stress, endoplasmic reticulum stress, and autophagy
    • Wang K., Niu J., Kim H., Kolattukudy P.E. Osteoclast precursor differentiation by MCPIP via oxidative stress, endoplasmic reticulum stress, and autophagy. J Mol Cell Biol 2011, 3:360-368.
    • (2011) J Mol Cell Biol , vol.3 , pp. 360-368
    • Wang, K.1    Niu, J.2    Kim, H.3    Kolattukudy, P.E.4
  • 24
    • 2042548006 scopus 로고    scopus 로고
    • Modeled microgravity inhibits osteogenic differentiation of human mesenchymal stem cells and increases adipogenesis
    • Zayzafoon M., Gathings W.E., McDonald J.M. Modeled microgravity inhibits osteogenic differentiation of human mesenchymal stem cells and increases adipogenesis. Endocrinology 2004, 145:2421-2432.
    • (2004) Endocrinology , vol.145 , pp. 2421-2432
    • Zayzafoon, M.1    Gathings, W.E.2    McDonald, J.M.3
  • 25
    • 0034970719 scopus 로고    scopus 로고
    • Simulated microgravity impairs respiratory burst activity in human promyelocytic cells
    • Hughes J.H., Long J.P. Simulated microgravity impairs respiratory burst activity in human promyelocytic cells. In Vitro Cell Dev Biol Anim 2001, 37:209-215.
    • (2001) In Vitro Cell Dev Biol Anim , vol.37 , pp. 209-215
    • Hughes, J.H.1    Long, J.P.2
  • 26
    • 36749023524 scopus 로고    scopus 로고
    • Transgenic mice with OIP-1/hSca overexpression targeted to the osteoclast lineage develop an osteopetrosis bone phenotype
    • Shanmugarajan S., Irie K., Musselwhite C., Key L.L., Ries W.L., Reddy S.V. Transgenic mice with OIP-1/hSca overexpression targeted to the osteoclast lineage develop an osteopetrosis bone phenotype. J Pathol 2007, 213:420-428.
    • (2007) J Pathol , vol.213 , pp. 420-428
    • Shanmugarajan, S.1    Irie, K.2    Musselwhite, C.3    Key, L.L.4    Ries, W.L.5    Reddy, S.V.6
  • 27
    • 69449094082 scopus 로고    scopus 로고
    • A novel function of CXCL13 to stimulate RANK ligand expression in oral squamous cell carcinoma cells
    • Yuvaraj S., Griffin A.C., Sundaram K., Kirkwood K.L., Norris J.S., Reddy S.V. A novel function of CXCL13 to stimulate RANK ligand expression in oral squamous cell carcinoma cells. Mol Cancer Res 2009, 7:1399-1407.
    • (2009) Mol Cancer Res , vol.7 , pp. 1399-1407
    • Yuvaraj, S.1    Griffin, A.C.2    Sundaram, K.3    Kirkwood, K.L.4    Norris, J.S.5    Reddy, S.V.6
  • 28
    • 80052589570 scopus 로고    scopus 로고
    • Autophagy regulates hypoxia-induced osteoclastogenesis through the HIF-1alpha/BNIP3 signaling pathway
    • Zhao Y., Chen G., Zhang W., Xu N., Zhu J.Y., Jia J., et al. Autophagy regulates hypoxia-induced osteoclastogenesis through the HIF-1alpha/BNIP3 signaling pathway. J Cell Physiol 2012, 227:639-648.
    • (2012) J Cell Physiol , vol.227 , pp. 639-648
    • Zhao, Y.1    Chen, G.2    Zhang, W.3    Xu, N.4    Zhu, J.Y.5    Jia, J.6
  • 29
    • 0034329418 scopus 로고    scopus 로고
    • LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
    • Kabeya Y., Mizushima N., Ueno T., Yamamoto A., Kirisako T., Noda T., et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000, 19:5720-5728.
    • (2000) EMBO J , vol.19 , pp. 5720-5728
    • Kabeya, Y.1    Mizushima, N.2    Ueno, T.3    Yamamoto, A.4    Kirisako, T.5    Noda, T.6
  • 30
    • 43949143804 scopus 로고    scopus 로고
    • The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy
    • Fujita N., Itoh T., Omori H., Fukuda M., Noda T., Yoshimori T. The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol Biol Cell 2008, 19:2092-2100.
    • (2008) Mol Biol Cell , vol.19 , pp. 2092-2100
    • Fujita, N.1    Itoh, T.2    Omori, H.3    Fukuda, M.4    Noda, T.5    Yoshimori, T.6
  • 32
    • 50249137038 scopus 로고    scopus 로고
    • Induction of macroautophagy by exogenously introduced calcium
    • Gao W., Ding W.X., Stolz D.B., Yin X.M. Induction of macroautophagy by exogenously introduced calcium. Autophagy 2008, 4:754-761.
    • (2008) Autophagy , vol.4 , pp. 754-761
    • Gao, W.1    Ding, W.X.2    Stolz, D.B.3    Yin, X.M.4
  • 35
    • 84883030202 scopus 로고    scopus 로고
    • Autophagy: A key pathway of TNF-induced inflammatory bone loss
    • Lin N.Y., Stefanica A., Distler J.H. Autophagy: A key pathway of TNF-induced inflammatory bone loss. Autophagy 2013, 9.
    • (2013) Autophagy , vol.9
    • Lin, N.Y.1    Stefanica, A.2    Distler, J.H.3
  • 36
    • 78549251353 scopus 로고    scopus 로고
    • Functional interaction between sequestosome-1/p62 and autophagy-linked FYVE-containing protein WDFY3 in human osteoclasts
    • Hocking L.J., Mellis D.J., McCabe P.S., Helfrich M.H., Rogers M.J. Functional interaction between sequestosome-1/p62 and autophagy-linked FYVE-containing protein WDFY3 in human osteoclasts. Biochem Biophys Res Commun 2010, 402:543-548.
    • (2010) Biochem Biophys Res Commun , vol.402 , pp. 543-548
    • Hocking, L.J.1    Mellis, D.J.2    McCabe, P.S.3    Helfrich, M.H.4    Rogers, M.J.5
  • 37
    • 84862784197 scopus 로고    scopus 로고
    • AQP9: a novel target for bone loss induced by microgravity
    • Bu G., Shuang F., Wu Y., Ren D., Hou S. AQP9: a novel target for bone loss induced by microgravity. Biochem Biophys Res Commun 2012, 419:774-778.
    • (2012) Biochem Biophys Res Commun , vol.419 , pp. 774-778
    • Bu, G.1    Shuang, F.2    Wu, Y.3    Ren, D.4    Hou, S.5
  • 38
    • 33845539490 scopus 로고    scopus 로고
    • Regulation of osteoclast differentiation and function by the CaMK-CREB pathway
    • Sato K., Suematsu A., Nakashima T., Takemoto-Kimura S., Aoki K., Morishita Y., et al. Regulation of osteoclast differentiation and function by the CaMK-CREB pathway. Nat Med 2006, 12:1410-1416.
    • (2006) Nat Med , vol.12 , pp. 1410-1416
    • Sato, K.1    Suematsu, A.2    Nakashima, T.3    Takemoto-Kimura, S.4    Aoki, K.5    Morishita, Y.6
  • 39
    • 84873199749 scopus 로고    scopus 로고
    • Space flight calcium: implications for astronaut health, spacecraft operations, and Earth
    • Smith S.M., McCoy T., Gazda D., Morgan J.L., Heer M., Zwart S.R. Space flight calcium: implications for astronaut health, spacecraft operations, and Earth. Nutrients 2012, 4:2047-2068.
    • (2012) Nutrients , vol.4 , pp. 2047-2068
    • Smith, S.M.1    McCoy, T.2    Gazda, D.3    Morgan, J.L.4    Heer, M.5    Zwart, S.R.6
  • 40
    • 0035413609 scopus 로고    scopus 로고
    • Structure and regulation of calcium/calmodulin-dependent protein kinases
    • Soderling T.R., Stull J.T. Structure and regulation of calcium/calmodulin-dependent protein kinases. Chem Rev 2001, 101:2341-2352.
    • (2001) Chem Rev , vol.101 , pp. 2341-2352
    • Soderling, T.R.1    Stull, J.T.2
  • 42
    • 84886819890 scopus 로고    scopus 로고
    • Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation
    • Liu F., Fang F., Yuan H., Yang D., Chen Y., Williams L., et al. Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation. J Bone Miner Res 2013, 28:2414-2430.
    • (2013) J Bone Miner Res , vol.28 , pp. 2414-2430
    • Liu, F.1    Fang, F.2    Yuan, H.3    Yang, D.4    Chen, Y.5    Williams, L.6
  • 43
    • 84879065741 scopus 로고    scopus 로고
    • Suppression of autophagy in osteocytes mimics skeletal aging
    • Onal M., Piemontese M., Xiong J., Wang Y., Han L., Ye S., et al. Suppression of autophagy in osteocytes mimics skeletal aging. J Biol Chem 2013, 288:17432-17440.
    • (2013) J Biol Chem , vol.288 , pp. 17432-17440
    • Onal, M.1    Piemontese, M.2    Xiong, J.3    Wang, Y.4    Han, L.5    Ye, S.6
  • 44
    • 85027934628 scopus 로고    scopus 로고
    • Ionizing Radiation and Bone Loss: Space Exploration and Clinical Therapy Applications
    • Willey J.S., Lloyd S.A., Nelson G.A., Bateman T.A. Ionizing Radiation and Bone Loss: Space Exploration and Clinical Therapy Applications. Clin Rev Bone Miner Metab 2011, 9:54-62.
    • (2011) Clin Rev Bone Miner Metab , vol.9 , pp. 54-62
    • Willey, J.S.1    Lloyd, S.A.2    Nelson, G.A.3    Bateman, T.A.4
  • 45
    • 84865614567 scopus 로고    scopus 로고
    • Effect of proton irradiation followed by hindlimb unloading on bone in mature mice: a model of long-duration spaceflight
    • Lloyd S.A., Bandstra E.R., Willey J.S., Riffle S.E., Tirado-Lee L., Nelson G.A., et al. Effect of proton irradiation followed by hindlimb unloading on bone in mature mice: a model of long-duration spaceflight. Bone 2012, 51:756-764.
    • (2012) Bone , vol.51 , pp. 756-764
    • Lloyd, S.A.1    Bandstra, E.R.2    Willey, J.S.3    Riffle, S.E.4    Tirado-Lee, L.5    Nelson, G.A.6
  • 46
    • 84887445881 scopus 로고    scopus 로고
    • Autophagy prevents irradiation injury and maintains stemness through decreasing ROS generation in mesenchymal stem cells
    • Hou J., Han Z.P., Jing Y.Y., Yang X., Zhang S.S., Sun K., et al. Autophagy prevents irradiation injury and maintains stemness through decreasing ROS generation in mesenchymal stem cells. Cell Death Dis 2013, 4:e844.
    • (2013) Cell Death Dis , vol.4
    • Hou, J.1    Han, Z.P.2    Jing, Y.Y.3    Yang, X.4    Zhang, S.S.5    Sun, K.6


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