Ex vivo acidic preconditioning enhances bone marrow ckit+ cell therapeutic potential via increased CXCR4 expression

European Heart Journal

Volumn 34, Issue 26, 2013, Pages 2007-2016

  Cencioni, Chiara ^a   Melchionna, Roberta ^b   Straino, Stefania ^b   Romani, Marta ^b   Cappuzzello, Claudia ^a   Annese, Valentina ^b   Wu, Joseph C ^d   Pompilio, Giulio ^a   Santoni, Angela ^c   Gaetano, Carlo ^b   Napolitano, Monica ^b   Capogrossi, Maurizio C ^b  

^a CENTRO CARDIOLOGICO MONZINO   (Italy)

^b LABORATORIO DI PATOLOGIA VASCOLARE   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cell migration; Cell therapy; Chemokines; Hindlimb ischaemia; Preconditioning

Indexed keywords

CALCIUM ION; CHEMOKINE RECEPTOR CXCR4; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; MESSENGER RNA; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; STROMAL CELL DERIVED FACTOR 1; 1,2-BIS(2-AMINOPHENOXY)ETHANE N,N,N',N'-TETRAACETIC ACID ACETOXYMETHYL ESTER; CHELATING AGENT; CXCL12 PROTEIN, MOUSE; EGTAZIC ACID; HIF1A PROTEIN, MOUSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NITRIC OXIDE DONOR; STEM CELL FACTOR RECEPTOR; 1,2 BIS(2 AMINOPHENOXY)ETHANE N,N,N',N' TETRAACETIC ACID ACETOXYMETHYL ESTER; CHEMOKINE; DRUG DERIVATIVE;

ACIDIC PRECONDITIONING; ACIDIFICATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIOLE; ARTICLE; BLOOD FLOW; BONE MARROW C KIT; CALCIUM MOBILIZATION; CELL ADHESION; CELL DEATH; CELL DIFFERENTIATION; CELL ISOLATION; CELL MIGRATION; CELL PROLIFERATION; CELL REGENERATION; CHEMOTAXIS; CONTROLLED STUDY; ENDOTHELIAL PROGENITOR CELL; EX VIVO STUDY; FUNCTION TEST KIT; HEART MUSCLE ISCHEMIA; HINDLIMB; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; ISCHEMIC PRECONDITIONING; LEG ISCHEMIA; MALE; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CYTOLOGY; ENDOTHELIUM CELL; ISCHEMIA; METABOLISM; PHYSIOLOGY; PROCEDURES; REGENERATION; VASCULARIZATION; CELL THERAPY; HINDLIMB ISCHAEMIA; METHODOLOGY; PRECONDITIONING;

ANIMALS; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CHELATING AGENTS; CHEMOKINE CXCL12; EGTAZIC ACID; ENDOTHELIAL CELLS; HINDLIMB; HYDROGEN-ION CONCENTRATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; ISCHEMIA; ISCHEMIC PRECONDITIONING; MALE; MICE; NITRIC OXIDE DONORS; PROTO-ONCOGENE PROTEINS C-KIT; RECEPTORS, CXCR4; REGENERATION;

CELL MIGRATION; CELL THERAPY; CHEMOKINES; HINDLIMB ISCHAEMIA; PRECONDITIONING;

EID: 84893481302     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehr219     Document Type: Article

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