All-trans retinoic acid (ATRA) induces miR-23a expression, decreases CTSC expression and granzyme B activity leading to impaired NK cell cytotoxicity

International Journal of Biochemistry and Cell Biology

Volumn 49, Issue 1, 2014, Pages 42-52

  Sanchez Martínez, Diego ^a   Krzywinska, Ewelina ^b   Rathore, Moeez G ^b   Saumet, Anne ^b   Cornillon, Amelie ^b   Lopez Royuela, Nuria ^b   Martínez Lostao, Luis ^a   Ramirez Labrada, Ariel ^a   Lu, Zhao Yang ^b   Rossi, Jean François ^b   Fernández Orth, Dietmar ^c   Escorza, Sergio ^c   Anel, Alberto ^a   Lecellier, Charles Henri ^d,f   Pardo, Julian ^a   Villalba, Martin ^b,e  

^a UNIVERSITY OF ZARAGOZA   (Spain)

^b INSERM   (France)

^c Progenika Biopharma SA   (Spain)

^d CNRS   (France)

^e MONTPELLIER UNIVERSITY HOSPITAL   (France)

^f UNIV MONTPELLIER   (France)

Author keywords

Cathepsin C; miR 23a; miRNA; NK cells; Transcriptomics

Indexed keywords

DIPEPTIDYL PEPTIDASE I; GRANZYME B; INTERLEUKIN 2; MICRORNA; MICRORNA 23A; RETINOIC ACID; UNCLASSIFIED DRUG; CTSC PROTEIN, MOUSE; GRANZYME; MIRN23 MICRORNA, HUMAN; MIRN23B MICRORNA, MOUSE; TRANSCRIPTOME;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVATION; CELL PROLIFERATION; CELL STIMULATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE RESPONSE; CYTOTOXICITY ASSAY; ENZYME ACTIVITY; EX VIVO STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NATURAL KILLER CELL; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; RNA ANALYSIS; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL LINE; CLUSTER ANALYSIS; CYTOTOXICITY; DNA MICROARRAY; DRUG EFFECTS; GENETICS; IMMUNOLOGY; JURKAT CELL LINE; K562 CELL LINE; METABOLISM; PRINCIPAL COMPONENT ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CATHEPSIN C; CELL LINE; CELLS, CULTURED; CLUSTER ANALYSIS; CYTOTOXICITY, IMMUNOLOGIC; FEMALE; GRANZYMES; HUMANS; INTERLEUKIN-2; JURKAT CELLS; K562 CELLS; KILLER CELLS, NATURAL; MICE, INBRED C57BL; MICRORNAS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PRINCIPAL COMPONENT ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTOME; TRETINOIN;

EID: 84893476736     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2014.01.003     Document Type: Article

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