The role of rs2237781 within GRM8 in eating behavior

Brain and Behavior

Volumn 3, Issue 5, 2013, Pages 495-502

  Gast, Marie Therese ^a   Tönjes, Anke ^a   Keller, Maria ^a   Horstmann, Annette ^a,b   Steinle, Nanette ^c,d   Scholz, Markus ^a   Müller, Ines ^a   Villringer, Arno ^a,b   Stumvoll, Michael ^a   Kovacs, Peter ^a   Böttcher, Yvonne ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b MAX PLANCK INSTITUTE FOR HUMAN COGNITIVE AND BRAIN SCIENCES   (Germany)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d BALTIMORE VA MEDICAL CENTER   (United States)

Author keywords

Addiction; Alcohol intake; Food intake; Human eating behavior; Smoking behavior

Indexed keywords

ARTICLE; CONTROLLED STUDY; FEEDING BEHAVIOR; GENE; GENE FREQUENCY; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCATION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPING TECHNIQUE; GERMANY; GLUTAMATE RECEPTOR METABOTROPIC 8 GENE; HUMAN; HUNGER; OUTCOME ASSESSMENT; PRIORITY JOURNAL; SCORING SYSTEM;

EID: 84893466835     PISSN: None     EISSN: 21623279     Source Type: Journal    
DOI: 10.1002/brb3.151     Document Type: Article

References (34)

1. ADA. 2010. ADA: standards of medical care in diabetes-2010. Diabetes Care 33:S11-S61.
2. Amin, N., C. M. van Duijn, and Y. S. Aulchenko 2007. A genomic background based method for association analysis in related individuals PLoS One 2:e1274.
3. Böttcher, Y., H. Unbehauen, N. Kloting, K. Ruschke, A. Korner, D. Schleinitz, et al. 2009. Adipose tissue expression and genetic variants of the bone morphogenetic protein receptor 1A gene (BMPR1A) are associated with human obesity. Diabetes 58:2119-2128.
4. Chen, A. C., Y. Tang, M. Rangaswamy, J. C. Wang, L. Almasy, T. Foroud, et al. 2009. Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B:359-368.
5. Cone, R. 2006. Studies on the physiological functions of the melanocortin system. Endocr. Rev. 27:736-749.
6. Dotson, C. D., L. Zhang, H. Xu, Y. K. Shin, S. Vigues, S. H. Ott, et al. 2008, Bitter taste receptors influence glucose homeostasis. PLoS One 3:e3974.
7. Dotson, C. D., H. L. Shaw, B. D. Mitchell, S. D. Munger, and N. I. Steinle 2010a. Variation in the gene TAS2R38 is associated with the eating behavior disinhibition in Old Order Amish women. Appetite 54:93-99.
8. Dotson, C. D., S. Vigues, N. I. Steinle, and S. D. Munger 2010b. T1R and T2R receptors: the modulation of incretin hormones and potential targets for the treatment of type 2 diabetes mellitus. Curr. Opin. Investig. Drugs 11:447-454.
9. Elia, J., J. T. Glessner, K. Wang, N. Takahashi, C. J. Shtir, D. Hadley, et al. 2011. Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder. Nat. Genet. 44:78-84.
10. Filbey, F. M., U. S. Myers, and S. Dewitt 2012. Reward circuit function in high BMI individuals with compulsive overeating: similarities with addiction. Neuroimage 63:1800-1806.
11. Gallant, A. R., A. Tremblay, L. Perusse, C. Bouchard, J.-P. Despres, and V. Drapeau 2010. The three-factor eating questionnaire and BMI in adolescents: results from the Quebec family study. Br. J. Nutr. 104:1074-1079
12. Grimm, E. R., and N. I. Steinle 2011. Genetics of eating behavior: established and emerging concepts. Nutr. Rev. 69:52-60.
13. Higgins, S. E., L. E. Ellestad, N. Trakooljul, F. McCarthy, J. Saliba, L. A. Cogburn, et al. 2010. Transcriptional and pathway analysis in the hypothalamus of newly hatched chicks during fasting and delayed feeding. BMC. Genomics 11:162.
14. Hsueh, W. C., B. D. Mitchell, R. Aburomia, T. Pollin, H. Sakul, E. M. Gelder, et al. 2000. Diabetes in the Old Order Amish: characterization and heritability analysis of the Amish Family Diabetes Study. Diabetes Care 23:595-601.
15. Johnson, P. M., and P. J. Kenny 2010. Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats. Nat. Neurosci. 13:635-641.
16. Kelley, A. E., C. A. Schiltz, and C. F. Landry 2005. Neural systems recruited by drug- and food-related cues: studies of gene activation in corticolimbic regions. Physiol. Behav. 86:11-14.
17. Li, H., Y. Li, J. Shao, R. Li, Y. Qin, C. Xie, et al. 2008. The association analysis of RELN and GRM8 genes with autistic spectrum disorder in Chinese Han population. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B:194-200.
18. Pandit, R., J. G. Mercer, J. Overduin, S. E. la Fleur, and R. A., Adan 2012. Dietary factors affect food reward and motivation to eat. Obes. Facts 5:221-242.
19. Pudel, V. and J. Westenhöfer 1989. Fragebogen zum Eßverhalten (FEV) Handanweisung. Hogrefe, Göttingen.
20. Rampersaud, E., C. M. Damcott, M. Fu, H. Shen, P. McArdle, X. Shi, et al. 2007. Identification of novel candidate genes for type 2 diabetes from a genome-wide association scan in the Old Order Amish: evidence for replication from diabetes-related quantitative traits and from independent populations. Diabetes 56:3053-3062.
21. Rangaswamy, M., and B. Porjesz 2008. Uncovering genes for cognitive (dys)function and predisposition for alcoholism spectrum disorders: a review of human brain oscillations as effective endophenotypes. Brain Res. 1235:153-171.
22. Robinson, T. E., and K. C. Berridge 2000. The psychology and neurobiology of addiction: an incentive-sensitization view. Addiction 95(Suppl. 2):S91-S117.
23. Stanley, B. G., V. L. Willett 3rd, H. W. Donias, L. H. Ha, and L.C. Spears 1993. The lateral hypothalamus: a primary site mediating excitatory amino acid-elicited eating. Brain Res. 630:41-49.
24. Steinle, N. I., W. C. Hsueh, S. Snitker, T. I. Pollin, H. Sakul, P. L. St Jean, et al. 2002. Eating behavior in the Old Order Amish: heritability analysis and a genome-wide linkage analysis. Am. J. Clin. Nutr. 75:1098-1106.
25. Stunkard, A. J., and S. Messick 1985. The three-factor eating questionnaire to measure dietary restraint, disinhibition and hunger. J. Psychosom. Res. 29:71-83.
26. Takaki, H., R. Kikuta, H. Shibata, H. Ninomiya, N. Tashiro, and Y. Fukumaki 2004. Positive associations of polymorphisms in the metabotropic glutamate receptor type 8 gene (GRM8) with schizophrenia. Am. J. Med. Genet. B Neuropsychiatr. Genet. 128B:6-14.
27. Terracciano, A., T. Tanaka, A. R. Sutin, S. Sanna, B. Deiana, S. Lai, et al. 2010. Genome-wide association scan of trait depression. Biol. Psychiatry 68:811-817.
28. Umberg, E. N., R. I. Shader, L. K. Hsu, and D. J. Greenblatt 2012. From disordered eating to addiction: the "food drug" in bulimia nervosa. J. Clin. Psychopharmacol. 32:376-389.
29. Veeramah, K. R., A. Tönjes, P. Kovacs, A. Gross, D. Wegmann, P. Geary, et al. 2011. Genetic variation in the Sorbs of eastern Germany in the context of broader European genetic diversity. Eur. J. Hum. Genet. 19:995-1001.
30. Vink, J. M., A. B. Smit, E. J. de Geus, P. Sullivan, G. Willemsen, J. J. Hottenga, et al. 2009. Genome-wide association study of smoking initiation and current smoking. Am. J. Hum. Genet. 84:367-379.
31. Volkow, N. D., and R. A. Wise 2005. How can drug addiction help us understand obesity? Nat. Neurosci. 8:555-560.
32. Volkow, N. D., G. J. Wang, J. S. Fowler, and F. Telang 2008. Overlapping neuronal circuits in addiction and obesity: evidence of systems pathology. Philos. Trans. R. Soc. Lond. B Biol. Sci. 363:3191-3200.
33. Volkow, N. D., G. J. Wang, J. S. Fowler, D. Tomasi, and R. Baler 2011. Food and drug reward: overlapping circuits in human obesity and addiction. Curr. Top. Behav. Neurosci. 11:1-24.
34. Volkow, N. D., G. J. Wang, D. Tomasi, and R. D. Baler 2013. Obesity and addiction: neurobiological overlaps. Obes. Rev. 14:2-18. doi: 10.1111/j.1467-789X.2012.01031.x.