-
2
-
-
34247161833
-
Cyclosporine and tacrolimus for the treatment of rheumatoid arthritis
-
DOI 10.1097/BOR.0b013e328099af80, PII 0000228120070500000003
-
Kitahara K, Kawai S (2007) Cyclosporine and tacrolimus for the treatment of rheumatoid arthritis. Curr Opin Rheumatol 19: 238-245. (Pubitemid 46597460)
-
(2007)
Current Opinion in Rheumatology
, vol.19
, Issue.3
, pp. 238-245
-
-
Kitahara, K.1
Kawai, S.2
-
3
-
-
0028292007
-
Cyclosporine in severe ulcerative colitis refractory to steroid therapy
-
DOI 10.1056/NEJM199406303302601
-
Lichtiger S, Present DH, Kornbluth A, Gelernt I, Bauer J, et al. (1994) Cyclosporine in severe ulcerative colitis refractory to steroid therapy. N Engl J Med 330: 1841-1845. (Pubitemid 24188135)
-
(1994)
New England Journal of Medicine
, vol.330
, Issue.26
, pp. 1841-1845
-
-
Lichtiger, S.1
Present, D.H.2
Kornbluth, A.3
Gelernt, I.4
Bauer, J.5
Galler, G.6
Michelassi, F.7
Hanauer, S.8
-
4
-
-
0028197044
-
Efficacy of cyclosporine in treatment of fistula of Crohn's disease
-
Present DH, Lichtiger S (1994) Efficacy of cyclosporine in treatment of fistula of Crohn's disease. Dig Dis Sci 39: 374-380. (Pubitemid 24073614)
-
(1994)
Digestive Diseases and Sciences
, vol.39
, Issue.2
, pp. 374-380
-
-
Present, D.H.1
Lichtiger, S.2
-
5
-
-
70349083694
-
Calcium signaling in cells of the immune and hematopoietic systems
-
Rao A, Hogan PG (2009) Calcium signaling in cells of the immune and hematopoietic systems. Immunol Rev 231: 5-9.
-
(2009)
Immunol Rev
, vol.231
, pp. 5-9
-
-
Rao, A.1
Hogan, P.G.2
-
6
-
-
34548233165
-
Calcium signalling in lymphocyte activation and disease
-
Feske S (2007) Calcium signalling in lymphocyte activation and disease. Nat Rev Immunol 7: 690-702.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 690-702
-
-
Feske, S.1
-
7
-
-
77950377028
-
Molecular basis of calcium signaling in lymphocytes: STIM and ORAI
-
Hogan PG, Lewis RS, Rao A (2010) Molecular basis of calcium signaling in lymphocytes: STIM and ORAI. Annu Rev Immunol 28: 491-533.
-
(2010)
Annu Rev Immunol
, vol.28
, pp. 491-533
-
-
Hogan, P.G.1
Lewis, R.S.2
Rao, A.3
-
8
-
-
33947243452
-
The molecular choreography of a store-operated calcium channel
-
Lewis RS (2007) The molecular choreography of a store-operated calcium channel. Nature 446: 284-287.
-
(2007)
Nature
, vol.446
, pp. 284-287
-
-
Lewis, R.S.1
-
9
-
-
33646576875
-
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function
-
Feske S, Gwack Y, Prakriya M, Srikanth S, Puppel SH, et al. (2006) A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature 441: 179-185.
-
(2006)
Nature
, vol.441
, pp. 179-185
-
-
Feske, S.1
Gwack, Y.2
Prakriya, M.3
Srikanth, S.4
Puppel, S.H.5
-
10
-
-
71449095831
-
ORAI1 deficiency and lack of store-operated Ca2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia
-
McCarl CA, Picard C, Khalil S, Kawasaki T, Rother J, et al. (2009) ORAI1 deficiency and lack of store-operated Ca2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia. J Allergy Clin Immunol 124: 1311-1318 e1317.
-
(2009)
J Allergy Clin Immunol
, vol.124
-
-
McCarl, C.A.1
Picard, C.2
Khalil, S.3
Kawasaki, T.4
Rother, J.5
-
11
-
-
0029794222
-
Severe combined immunodeficiency due to defective binding of the nuclear factor of activated T cells in T lymphocytes of two male siblings
-
Feske S, Muller JM, Graf D, Kroczek RA, Drager R, et al. (1996) Severe combined immunodeficiency due to defective binding of the nuclear factor of activated T cells in T lymphocytes of two male siblings. Eur J Immunol 26: 2119-2126. (Pubitemid 26297511)
-
(1996)
European Journal of Immunology
, vol.26
, Issue.9
, pp. 2119-2126
-
-
Feske, S.1
Muller, J.M.2
Graf, D.3
Kroczek, R.A.4
Drager, R.5
Niemeyer, C.6
Baeuerle, P.A.7
Peter, H.-H.8
Schlesier, M.9
-
12
-
-
0028589615
-
The calcium current activated by T cell receptor and store depletion in human lymphocytes is absent in a primary immunodeficiency
-
Partiseti M, Le Deist F, Hivroz C, Fischer A, Korn H, et al. (1994) The calcium current activated by T cell receptor and store depletion in human lymphocytes is absent in a primary immunodeficiency. J Biol Chem 269: 32327-32335.
-
(1994)
J Biol Chem
, vol.269
, pp. 32327-32335
-
-
Partiseti, M.1
Le Deist, F.2
Hivroz, C.3
Fischer, A.4
Korn, H.5
-
13
-
-
0028938578
-
A primary T-cell immunodeficiency associated with defective transmembrane calcium influx
-
Le Deist F, Hivroz C, Partiseti M, Thomas C, Buc HA, et al. (1995) A primary T-cell immunodeficiency associated with defective transmembrane calcium influx. Blood 85: 1053-1062.
-
(1995)
Blood
, vol.85
, pp. 1053-1062
-
-
Le Deist, F.1
Hivroz, C.2
Partiseti, M.3
Thomas, C.4
Buc, H.A.5
-
14
-
-
50249165416
-
Hair loss and defective T- and B-cell function in mice lacking ORAI1
-
Gwack Y, Srikanth S, Oh-Hora M, Hogan PG, Lamperti ED, et al. (2008) Hair loss and defective T- and B-cell function in mice lacking ORAI1. Mol Cell Biol 28: 5209-5222.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5209-5222
-
-
Gwack, Y.1
Srikanth, S.2
Oh-Hora, M.3
Hogan, P.G.4
Lamperti, E.D.5
-
15
-
-
78650653524
-
Store-operated Ca2+ entry through ORAI1 is critical for T cell-mediated autoimmunity and allograft rejection
-
McCarl CA, Khalil S, Ma J, Oh-hora M, Yamashita M, et al. (2010) Store-operated Ca2+ entry through ORAI1 is critical for T cell-mediated autoimmunity and allograft rejection. J Immunol 185: 5845-5858.
-
(2010)
J Immunol
, vol.185
, pp. 5845-5858
-
-
McCarl, C.A.1
Khalil, S.2
Ma, J.3
Oh-hora, M.4
Yamashita, M.5
-
16
-
-
33748548406
-
2+ entry: Local activation of CRAC channels by STIM1 at ER-plasma membrane junctions
-
DOI 10.1083/jcb.200604015
-
Luik RM, Wu MM, Buchanan J, Lewis RS (2006) The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER-plasma membrane junctions. J Cell Biol 174: 815-825. (Pubitemid 44373731)
-
(2006)
Journal of Cell Biology
, vol.174
, Issue.6
, pp. 815-825
-
-
Luik, R.M.1
Wu, M.M.2
Buchanan, J.3
Lewis, R.S.4
-
17
-
-
33748569838
-
2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane
-
DOI 10.1083/jcb.200604014
-
Wu MM, Buchanan J, Luik RM, Lewis RS (2006) Ca2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane. J Cell Biol 174: 803-813. (Pubitemid 44373730)
-
(2006)
Journal of Cell Biology
, vol.174
, Issue.6
, pp. 803-813
-
-
Wu, M.M.1
Buchanan, J.2
Luik, R.M.3
Lewis, R.S.4
-
18
-
-
84870655957
-
Crystal structure of the calcium release-activated calcium channel Orai
-
Hou X, Pedi L, Diver MM, Long SB (2012) Crystal structure of the calcium release-activated calcium channel Orai. Science 338: 1308-1313.
-
(2012)
Science
, vol.338
, pp. 1308-1313
-
-
Hou, X.1
Pedi, L.2
Diver, M.M.3
Long, S.B.4
-
19
-
-
61349137530
-
STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1
-
Park CY, Hoover PJ, Mullins FM, Bachhawat P, Covington ED, et al. (2009) STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1. Cell 136: 876-890.
-
(2009)
Cell
, vol.136
, pp. 876-890
-
-
Park, C.Y.1
Hoover, P.J.2
Mullins, F.M.3
Bachhawat, P.4
Covington, E.D.5
-
20
-
-
0242521406
-
2+/calcineurin signalling in cells of the immune system
-
DOI 10.1016/j.bbrc.2003.09.174
-
Feske S, Okamura H, Hogan PG, Rao A (2003) Ca2+/calcineurin signalling in cells of the immune system. Biochem Biophys Res Commun 311: 1117-1132. (Pubitemid 37393435)
-
(2003)
Biochemical and Biophysical Research Communications
, vol.311
, Issue.4
, pp. 1117-1132
-
-
Feske, S.1
Okamura, H.2
Hogan, P.G.3
Rao, A.4
-
21
-
-
0141483523
-
Transcriptional regulation by calcium, calcineurin, and NFAT
-
DOI 10.1101/gad.1102703
-
Hogan PG, Chen L, Nardone J, Rao A (2003) Transcriptional regulation by calcium, calcineurin, and NFAT. Genes Dev 17: 2205-2232. (Pubitemid 37128637)
-
(2003)
Genes and Development
, vol.17
, Issue.18
, pp. 2205-2232
-
-
Hogan, P.G.1
Chen, L.2
Nardone, J.3
Rao, A.4
-
22
-
-
65649088588
-
STIM1 mutation associated with a syndrome of immunodeficiency and autoimmunity
-
Picard C, McCarl CA, Papolos A, Khalil S, Luthy K, et al. (2009) STIM1 mutation associated with a syndrome of immunodeficiency and autoimmunity. N Engl J Med 360: 1971-1980.
-
(2009)
N Engl J Med
, vol.360
, pp. 1971-1980
-
-
Picard, C.1
McCarl, C.A.2
Papolos, A.3
Khalil, S.4
Luthy, K.5
-
23
-
-
33747643506
-
Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1
-
DOI 10.1074/jbc.M604589200
-
Mercer JC, Dehaven WI, Smyth JT, Wedel B, Boyles RR, et al. (2006) Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1. J Biol Chem 281: 24979-24990. (Pubitemid 44274268)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.34
, pp. 24979-24990
-
-
Mercer, J.C.1
DeHaven, W.I.2
Smyth, J.T.3
Wedel, B.4
Boyles, R.R.5
Bird, G.S.6
Putney Jr., J.W.7
-
24
-
-
27144549916
-
Generation of functional ion-channel tools by E3 targeting
-
DOI 10.1038/nbt1148, PII N1148
-
Xu SZ, Zeng F, Lei M, Li J, Gao B, et al. (2005) Generation of functional ion-channel tools by E3 targeting. Nat Biotechnol 23: 1289-1293. (Pubitemid 41486857)
-
(2005)
Nature Biotechnology
, vol.23
, Issue.10
, pp. 1289-1293
-
-
Xu, S.-Z.1
Zeng, F.2
Lei, M.3
Li, J.4
Gao, B.5
Xiong, C.6
Sivaprasadarao, A.7
Beech, D.J.8
-
25
-
-
34547636154
-
Monoclonal antibody blockade of the human Eag1 potassium channel function exerts antitumor activity
-
DOI 10.1158/0008-5472.CAN-07-0107
-
Gomez-Varela D, Zwick-Wallasch E, Knotgen H, Sanchez A, Hettmann T, et al. (2007) Monoclonal antibody blockade of the human Eag1 potassium channel function exerts antitumor activity. Cancer Res 67: 7343-7349. (Pubitemid 47206564)
-
(2007)
Cancer Research
, vol.67
, Issue.15
, pp. 7343-7349
-
-
Gomez-Varela, D.1
Zwick-Wallasch, E.2
Knotgen, H.3
Sanchez, A.4
Hettmann, T.5
Ossipov, D.6
Weseloh, R.7
Contreras-Jurado, C.8
Rothe, M.9
Stuhmer, W.10
Pardo, L.A.11
-
26
-
-
84860489733
-
The antibody targeting the E314 peptide of human Kv1.3 pore region serves as a novel, potent and specific channel blocker
-
Yang XF, Yang Y, Lian YT, Wang ZH, Li XW, et al. (2012) The antibody targeting the E314 peptide of human Kv1.3 pore region serves as a novel, potent and specific channel blocker. PLoS One 7: e36379.
-
(2012)
PLoS One
, vol.7
-
-
Yang, X.F.1
Yang, Y.2
Lian, Y.T.3
Wang, Z.H.4
Li, X.W.5
-
27
-
-
84876524918
-
Generation and characterization of fully human monoclonal antibodies against human Orai1 for autoimmune disease
-
Lin FF, Elliott R, Colombero A, Gaida K, Kelley L, et al. (2013) Generation and characterization of fully human monoclonal antibodies against human Orai1 for autoimmune disease. J Pharmacol Exp Ther 345: 225-238.
-
(2013)
J Pharmacol Exp Ther
, vol.345
, pp. 225-238
-
-
Lin, F.F.1
Elliott, R.2
Colombero, A.3
Gaida, K.4
Kelley, L.5
-
28
-
-
0035932519
-
Cytokine pathways and joint inflamation in rheumatoid arthritis
-
DOI 10.1056/NEJM200103223441207
-
Choy EH, Panayi GS (2001) Cytokine pathways and joint inflammation in rheumatoid arthritis. N Engl J Med 344: 907-916. (Pubitemid 32224400)
-
(2001)
New England Journal of Medicine
, vol.344
, Issue.12
, pp. 907-916
-
-
Choy, E.H.S.1
Panayi, G.S.2
-
29
-
-
67649580473
-
Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice
-
Ito R, Katano I, Kawai K, Hirata H, Ogura T, et al. (2009) Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice. Transplantation 87: 1654-1658.
-
(2009)
Transplantation
, vol.87
, pp. 1654-1658
-
-
Ito, R.1
Katano, I.2
Kawai, K.3
Hirata, H.4
Ogura, T.5
-
30
-
-
84893494839
-
Human T cells depend on functional calcineurin, TNFa and CD80/CD86 for expansion and activation in mice
-
In press
-
Sondergaard H, Kvist P, Haase C (In press) Human T cells depend on functional calcineurin, TNFa and CD80/CD86 for expansion and activation in mice. Clinical and Experimental Immunology.
-
Clinical and Experimental Immunology
-
-
Sondergaard, H.1
Kvist, P.2
Haase, C.3
-
31
-
-
70349162817
-
The functional network of ion channels in T lymphocytes
-
Cahalan MD, Chandy KG (2009) The functional network of ion channels in T lymphocytes. Immunol Rev 231: 59-87.
-
(2009)
Immunol Rev
, vol.231
, pp. 59-87
-
-
Cahalan, M.D.1
Chandy, K.G.2
-
32
-
-
33748655172
-
Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai
-
DOI 10.1038/nature05108, PII NATURE05108
-
Yeromin AV, Zhang SL, Jiang W, Yu Y, Safrina O, et al. (2006) Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai. Nature 443: 226-229. (Pubitemid 44387612)
-
(2006)
Nature
, vol.443
, Issue.7108
, pp. 226-229
-
-
Yeromin, A.V.1
Zhang, S.L.2
Jiang, W.3
Yu, Y.4
Safrina, O.5
Cahalan, M.D.6
-
33
-
-
33748669602
-
Orai1 is an essential pore subunit of the CRAC channel
-
DOI 10.1038/nature05122, PII NATURE05122
-
Prakriya M, Feske S, Gwack Y, Srikanth S, Rao A, et al. (2006) Orai1 is an essential pore subunit of the CRAC channel. Nature 443: 230-233. (Pubitemid 44387613)
-
(2006)
Nature
, vol.443
, Issue.7108
, pp. 230-233
-
-
Prakriya, M.1
Feske, S.2
Gwack, Y.3
Srikanth, S.4
Rao, A.5
Hogan, P.G.6
-
35
-
-
57849148942
-
Calcium signaling in immune cells
-
Vig M, Kinet JP (2009) Calcium signaling in immune cells. Nat Immunol 10: 21-27.
-
(2009)
Nat Immunol
, vol.10
, pp. 21-27
-
-
Vig, M.1
Kinet, J.P.2
-
36
-
-
77449102708
-
Orai1 regulates intracellular calcium, arrest, and shape polarization during neutrophil recruitment in shear flow
-
Schaff UY, Dixit N, Procyk E, Yamayoshi I, Tse T, et al. (2010) Orai1 regulates intracellular calcium, arrest, and shape polarization during neutrophil recruitment in shear flow. Blood 115: 657-666.
-
(2010)
Blood
, vol.115
, pp. 657-666
-
-
Schaff, U.Y.1
Dixit, N.2
Procyk, E.3
Yamayoshi, I.4
Tse, T.5
|